Modification of host cell apoptosis by viral and bacterial pathogens

International Journal of Medical Microbiology

Volumn 291, Issue 3, 2001, Pages 197-207

  Müller, Anne ^a   Rudel, Thomas ^a  

^a Abteilung Molekulare Biologie   (Germany)

Author keywords

Bcl 2; Caspase; Death receptor; Mitochondria; v FLIP; v IAP

Indexed keywords

EID: 0034878044     PISSN: 14384221     EISSN: None     Source Type: Journal    
DOI: 10.1078/1438-4221-00125     Document Type: Article

References (91)

1. The tranquilizing injection of Yersinia proteins: A pathogen's strategy to resist host defense
2. An African swine fever virus Bcl-2 homolog, 5-HL, suppresses apoptotic cell death
3. Death receptors: Signaling and modulation
4. Bik, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins
5. Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins
6. The Rel/NF-kappa B family directly activates expression of the apoptosis inhibitor Bcl-x(L)
7. Adenovirus E1B 19-kDa death suppressor protein interacts with Bax but not with Bad
8. Salmonella spp. are cytotoxic for cultured macrophages
9. A bacterial invasin induces macrophage apoptosis by binding directly to ICE
10. Functional complementation of the adenovirus E1B 19-kilodalton protein with Bcl-2 in the inhibition of apoptosis in infected cells
11. Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NFκB control
12. The iap genes - Unique arbitrators of cell death
13. Prevention of apoptosis by a baculovirus gene during infection of insect cells
14. NF-kappa B-dependent inhibition of apoptosis is essential for host cell survival during Rickettsia rickettsii infection
15. Host cell death due to enteropathogenic Escherichia coli has features of apoptosis
16. The vacuolating toxin from Helicobacter pylori forms hexameric pores in lipid bilayers at low pH
17. Persistent Chlamydia trachomatis infections resist apoptotic stimuli
18. Antiapoptotic activity of the herpesvirus saimiri-encoded Bcl-2 homolog: Stabilization of mitochondria and inhibition of caspase-3-like activity
19. IAP family proteins - Suppressors of apoptosis
20. IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases
21. X-linked IAP is a direct inhibitor of cell-death proteases
22. DIABLO promotes apoptosis by removing MIHA/XIAP from processed caspase 9
23. M11L: A novel mitochondria-localized protein of myxoma virus that blocks apoptosis of infected leukocytes
24. Inhibition of apoptosis in Chlamydia-infected cells: Blockade of mitochondrial cytochrome c release and caspase activation
25. Cloning of a bcl-2 homologue by interaction with adenovirus E1B
26. The N-terminal 34 kDa fragment of Helicobacter pylori vacuolating cytotoxin targets mitochondria and induces cytochrome c release
27. Chlamydia pneumoniae inhibits apoptosis in human peripheral blood mononuclear cells through induction of IL-10
28. Induction of apoptosis by Chlamydia psittaci and Chlamydia trachomatis infection in tissue culture cells
29. Mitochondria and apoptosis
30. Anti- and pro-apoptotic activities of baculovirus and Drosophila IAPs in an insect cell line
31. Anti-apoptotic potential of insect cellular and viral IAPs in mammalian cells
32. Epstein-Barr virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death
33. The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1
34. Shigella-induced apoptosis is dependent on caspase-1 which binds to IpaB
35. The BIR motifs mediate dominant interference and oligomerization of inhibitor of apoptosis Op-IAP
36. A splice-isoform of vesicle-associated membrane protein-1 (VAMP-1) contains a mitochondrial targeting signal
37. Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein R and Bcl-2
38. The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore
39. Protective role of Raf-1 in Salmonella-induced macrophage apoptosis
40. Salmonella-induced caspase-2 activation in macrophages: A novel mechanism in pathogen-mediated apoptosis
41. FLIP prevents apoptosis induced by death receptors but not by perforin/granzyme B, chemotherapeutic drugs, and gamma irradiation
42. Targeting of an enteropathogenic Escherichia coli (EPEC) effector protein to host mitochondria
43. The pro-apoptotic proteins, Bid and Bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol
44. Herpesvirus saimiri transforms human T-cell clones to stable growth without inducing resistance to apoptosis
45. The proto-oncogene Bcl-2 and its role in regulating apoptosis
46. Chlamydia pneumoniae
47. Caspase inhibitor P35 and inhibitor of apoptosis Op-IAP block in vivo proteolytic activation of an effector caspase at different steps
48. Neisseria meningitidis porin PorB interacts with mitochondria and protects cells from apoptosis
49. Anti-apoptotic strategies of lymphotropic viruses
50. Baculovirus regulation of apoptosis
51. Yersinia enterocolitica induces apoptosis in macrophages by a process requiring functional type III secretion and translocation mechanisms and involving YopP, presumably acting as an effector protein
52. Salmonella exploits caspase-1 to colonize Peyer's patches in a murine typhoid model
53. Yersinia-induced apoptosis in vivo aids in the establishment of a systemic infection of mice
54. Yersinia signals macrophages to undergo apoptosis and YopJ is necessary for this cell death
55. Salmonella typhimurium invasion induces apoptosis in infected macrophages
56. Targeting of the pro-apoptotic VDAC-like porin (PorB) of Neisseria gonorrhoeae to mitochondria of infected cells
57. Neisserial porin (PorB) causes rapid calcium influx in target cells and induces apoptosis by the activation of cysteine proteases
58. FLICE, a novel FADD-homologous ICE/CED-3-1ike protease, is recruited to the CD95 (Fas/Apo-1) death-inducing signaling complex
59. An African swine fever virus gene with similarity to the proto-oncogene bcl-2 and the Epstein-Barr virus gene BHRF1
60. African swine fever virus IAP homologue inhibits caspase activation and promotes cell survival in mammalian cells
61. Apoptosis of epithelial cells and macrophages due to infection with the obligate intracellular pathogen Chlamydia psittaci
62. Inhibition of the mitogen-activated protein kinase kinase superfamily by a Yersinia effector
63. Hepatitis B virus X protein colocalizes to mitochondria with a human voltage-dependent anion channel, HVDAC3, and alters its transmembrane potential
64. Viral inhibition of inflammation: Cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme
65. Double identity for proteins of the Bcl-2 family
66. Yersinia enterocolitica impairs activation of transcription factor NF-kappaB: Involvement in the induction of programmed cell death and in the suppression of the macrophage tumor necrosis factor alpha production
67. Yersinia outer protein P of Yersinia enterocolitica simultaneously blocks the nuclear factor-kappa B pathway and exploits lipopolysaccharide signaling to trigger apoptosis in macrophages
68. Interaction of Yersinia enterocolitica with macrophages leads to macrophage cell death through apoptosis
69. Modulation of Neisseria porin (PorB) by cytosolic ATP/GTP of target cells: Parallels between pathogen accommodation and mitochondrial endosymbiosis
70. Role of interleukin-1 in the pathogenesis of experimental shigellosis
71. The yopJ locus is required for Yersinia-mediated inhibition of NF-kappaB activation and cytokine expression: YopJ contains a eukaryotic SH2-like domain that is essential for its repressive activity
72. A novel viral homologue of Bcl-2 and Ced-9
73. A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis
74. Human immunodeficiency virus type 1 Vpr induces apoptosis following cell cycle arrest
75. Death by a thousand cuts: An ever increasing list of caspase substrates
76. Expression of K13/v-FLIP gene of human herpesvirus 8 and apoptosis in Kaposi's sarcoma spindle cells
77. Formation of anion-selective channels in the cell plasma membrane by the toxin VacA of Helicobacter pylori is required for its biological activity
78. Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors
79. Helicobacter pylori vacuolating toxin forms anion-selective channels in planar lipid bilayers: Possible implications for the mechanism of cellular vacuolation
80. Preservation of mitochondrial structure and function after Bid- or Bax-mediated cytochrome c release
81. NF-kappaB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
82. Fate of the major outer membrane protein P.IA in early and late events of gonococcal infection of epithelial cells
83. An atlas of serpin conformations
84. Inhibition of the Caenorhabditis elegans cell-death protease ced-3 by a ced-3 cleavage site in baculovirus p35 protein
85. Vpr stimulates viral expression and induces cell killing in human immunodeficiency virus type 1-infected dividing Jurkat T cells
86. Target protease specificity of the viral serpin CrmA. Analysis of five caspases
87. Interleukin 1 is released by murine macrophages during apoptosis induced by Shigella flexneri
88. IpaB mediates macrophage apoptosis induced by Shigella flexneri
89. Shigella flexneri induces apoptosis in infected macrophages
90. In vivo apoptosis in Shigella flexneri infections