메뉴 건너뛰기




Volumn 8, Issue 8, 2001, Pages 817-829

Analysis of the prodiginine biosynthesis gene cluster of Streptomyces coelicolor A3(2): New mechanisms for chain initiation and termination in modular multienzymes

Author keywords

Antibiotic; Fatty acid synthase; Modular polyketide synthase; Non ribosomal peptide synthetase; Streptomyces

Indexed keywords

BACTERIAL GENE; BIOCHEMICAL PATHWAY; GENE CLUSTER; GENE FUNCTION; GENE KNOCKOUT; GENETIC ENGINEERING; PRODIGININE; UNDECYLPRODIGININE;

EID: 0034872156     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(01)00054-0     Document Type: Article
Times cited : (169)

References (92)
  • 4
    • 0015117052 scopus 로고
    • Prodigiosin-like pigments from Actinomadura (Nocardia) pelletieri
    • (1971) J. Antibiot. , vol.24 , pp. 636-640
    • Gerber, N.N.1
  • 14
    • 0031003926 scopus 로고    scopus 로고
    • Syntheses via vinyl sulfones. 71. Application of the Grubbs ring-closing metathesis for the construction of a macrocyclic ansa-bridge. Synthesis of the tricyclic core of roseophilin
    • (1997) Tetrahedron Lett. , vol.38 , pp. 2601-2604
    • Kim, S.H.1    Figueroa, I.2    Fuchs, P.L.3
  • 36
    • 0031016476 scopus 로고    scopus 로고
    • bldA dependence of undecylprodigiosin production in Streptomyces coelicolor A3(2) involves a pathway-specific regulatory cascade
    • (1997) J. Bacteriol. , vol.179 , pp. 627-633
    • White, J.1    Bibb, M.J.2
  • 44
    • 0030922782 scopus 로고    scopus 로고
    • The ppGpp synthetase gene (relA) of Streptomyces coelicolor A3(2) plays a conditional role in antibiotic production and morphological differentiation
    • (1997) J. Bacteriol. , vol.179 , pp. 5854-5861
    • Chakraburtty, R.1    Bibb, M.2
  • 49
    • 0026603151 scopus 로고
    • The 8-amino-7-oxopelargonate synthase from Bacillus sphaericus. Purification and preliminary characterization of the cloned enzyme overproduced in Escherichia coli
    • (1992) Biochem. J. , vol.283 , pp. 327-331
    • Ploux, O.1    Marquet, A.2
  • 56
    • 0030731108 scopus 로고    scopus 로고
    • The complete genome sequence of the Gram-positive bacterium Bacillus subtilis
    • (1997) Nature , vol.390 , pp. 249-256
    • Kunst, F.1    Ogasawara, N.2
  • 57
    • 0001747786 scopus 로고    scopus 로고
    • Genetic contributions to understanding polyketide synthases
    • (1997) Chem. Rev. , vol.97 , pp. 2465-2497
    • Hopwood, D.A.1
  • 62
    • 0034711399 scopus 로고    scopus 로고
    • Dissecting the chain length specificity in bacterial aromatic polyketide synthases using chimeric genes
    • (2000) Tetrahedron , vol.56 , pp. 9401-9408
    • Burson, K.K.1    Khosla, C.2
  • 68
    • 0029762312 scopus 로고    scopus 로고
    • afsR is a pleiotropic but conditionally required regulatory gene for antibiotic production in Streptomyces coelicolor A3(2)
    • (1996) Mol. Microbiol. , vol.21 , pp. 385-396
    • Floriano, B.1    Bibb, M.2
  • 72
    • 0033835373 scopus 로고    scopus 로고
    • The biosynthetic gene cluster for the antitumor drug bleomycin from Streptomyces verticillus ATCC15003 supporting functional interactions between nonribosomal peptide synthetases and a polyketide synthase
    • (2000) Chem. Biol. , vol.7 , pp. 623-642
    • Du, L.1    Sanchez, C.2    Chen, M.3    Edwards, D.J.4    Shen, B.5
  • 90
    • 0027459427 scopus 로고
    • Derivatives of pUC18 that have BglII sites flanking a modified multiple cloning site and that retain the ability to identify recombinant clones by visual screening of Escherichia coli colonies
    • (1993) Gene , vol.124 , pp. 133-134
    • Jansen, G.R.1    Bibb, M.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.