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Volumn 73, Issue 5, 2001, Pages 859-871

Murine models for Down syndrome

Author keywords

BAC; Central nervous system; Down syndrome; Hypotonia; Learning; Memory; Mental retardation; Mouse; Transgenic; Trisomic; YAC

Indexed keywords

DNA; GENE PRODUCT; PROTEOME;

EID: 0034837339     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9384(01)00523-6     Document Type: Article
Times cited : (59)

References (100)
  • 6
    • 0026307123 scopus 로고
    • Genesis and systematization of cardiovascular anomalies in murine trisomy 16
    • Epstein CJ, editor. The morphogenesis of Down syndrome. New York: Wiley-Liss
    • (1991) , pp. 203-214
    • Buselmaier, W.1    Bachus, C.2    Sterz, H.3
  • 9
    • 10144231437 scopus 로고    scopus 로고
    • Novel neuritic clusters with accumulations of amyloid precursor protein and amyloid precursor-like protein 2 immunoreactivity in brain regions damaged by thiamine deficiency
    • (1996) Am J Pathol , vol.149 , pp. 1063-1071
    • Calingasan, N.Y.1    Gandy, S.E.2
  • 12
  • 14
    • 0031171578 scopus 로고    scopus 로고
    • A proposed test battery and constellations of specific behavioral paradigms to investigate the behavioral phenotypes of transgenic and knockout mice
    • (1997) Horm Behav , vol.31 , pp. 197-211
    • Crawley, J.1    Paylor, R.2
  • 16
    • 0025663975 scopus 로고
    • Segmental trisomy for murine chromosome 16: A new system for studying Down syndrome
    • Patterson D, Epstein CJ, editors. Molecular genetics of chromosome 21 and Down syndrome. New York: Wiley-Liss
    • (1990) , pp. 263-280
    • Davisson, M.T.1    Schmidt, C.2    Akeson, E.C.3
  • 23
    • 0000521855 scopus 로고
    • The metabolic and molecular basis of inherited disease
    • Scriver CR, Beaudet AL, Sly WS, Valle D, editors. New York: McGraw-Hill
    • (1995) Down syndrome, 7th ed. , vol.1
    • Epstein, C.J.1
  • 26
    • 0001831958 scopus 로고
    • Neurologic abnormalities
    • Pueschel SM, Pueschel JK, editors. Biomedical concerns in persons with Down syndrome. Baltimore (MD): Paul H. Brookes Publishing
    • (1992) , pp. 159-173
    • Flórez, J.1
  • 30
    • 0029940557 scopus 로고    scopus 로고
    • Gene targeting studies of mammalian behavior: Is it the mutation or the background phenotype?
    • (1996) Trends Neurosci , vol.19 , pp. 177-181
    • Gerlai, R.1
  • 31
  • 44
    • 0034639935 scopus 로고    scopus 로고
    • Analysis of mammalian central nervous system gene expression and function using bacterial artificial chromosome-mediated transgenesis
    • (2000) Hum Mol Genet , vol.9 , pp. 937-943
    • Heintz, N.1
  • 53
    • 0030854138 scopus 로고    scopus 로고
    • Animal models in the study of the biological function of genes on HSA21 and their role in the pathophysiology of Down syndrome
    • (1997) Hum Mol Genet , vol.6 , pp. 1713-1727
    • Kola, I.1    Hertzog, P.2
  • 66
    • 0032536811 scopus 로고    scopus 로고
    • Twofold overexpression of human beta-amyloid precursor proteins in transgenic mice does not affect the neuromotor cognitive or neurodegenerative sequelae following experimental brain injury
    • (1998) Comp Neurol , vol.392 , pp. 428-438
    • Murai, H.1    Pierce, J.E.2
  • 67
    • 0030056448 scopus 로고    scopus 로고
    • Application of antisense DNA method for the study of molecular bases of brain function and behavior
    • (1996) Behav Genet , vol.26 , pp. 279-292
    • Ogawa, S.1    Pfaff, D.W.2
  • 75
    • 0003596471 scopus 로고
    • Phenotypic characteristics
    • Pueschel SM, Pueschel JK, editors. Biomedical concerns in persons with Down syndrome. Baltimore (MD): Paul H. Brookes Publishing
    • (1992) , pp. 1-12
    • Pueschel, S.M.1
  • 89
    • 0030915187 scopus 로고    scopus 로고
    • Functional screening of 2 Mb of HSA21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome
    • (1997) Nat Genet , vol.16 , pp. 28-36
    • Smith, D.J.1    Stevens, M.E.2
  • 99
    • 0030842624 scopus 로고    scopus 로고
    • Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome
    • (1997) Nat Biotechnol , vol.15 , pp. 859-865
    • Yang, X.W.1    Model, P.2    Heintz, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.