A critical evaluation of the application of biomarkers in epidemiological studies on diet and health

British Journal of Nutrition

Volumn 86, Issue SUPPL. 1, 2001, Pages

  Wild, C P ^a   Andersson, C ^b   O'Brien, N M ^c   Wilson, L ^d   Woods, J A ^c  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b NATIONAL FOOD ADMINISTRATION   (Sweden)

^c UNIVERSITY COLLEGE CORK   (Ireland)

^d CENTRAL SCIENCE LABORATORY   (United Kingdom)

Author keywords

Biomarkers; Diet and health; Dietary intake; Epidemiological studies

Indexed keywords

BIOLOGICAL MARKER; DAIDZEIN; FOLIC ACID; GENISTEIN; HETEROCYCLIC AMINE; IODINE; PHYTOESTROGEN; VITAMIN D;

ACCURACY; ANALYTICAL PARAMETERS; COLORECTAL CANCER; CORRELATION FUNCTION; DIET; DIETARY INTAKE; DISEASE COURSE; EPIDEMIOLOGICAL DATA; EVALUATION; FACTORIAL ANALYSIS; FOOD COMPOSITION; FOOD CONTAMINATION; HEALTH STATUS; HOMEOSTASIS AND REGULATION; INFORMATION; INFORMATION PROCESSING; MEAT; MEMORY; NEURAL TUBE DEFECT; POPULATION; PROSPECTIVE STUDY; PROSTATE CANCER; REFERENCE VALUE; RELIABILITY; REVIEW; RISK ASSESSMENT; RISK FACTOR; SAMPLE; SELF REPORT; TIME; URINE LEVEL;

EID: 0034814121     PISSN: 00071145     EISSN: None     Source Type: Journal    
DOI: 10.1079/bjn2001338     Document Type: Review

References (138)

1. Dietary lignans and isoflavonoid phytoestrogens, and cancer
2. Phytoestrogens: Epidemiology and a possible role in cancer protection
3. Determination of urinary lignans and phytoestrogen metabolites, potential antiestrogens and anticarcinogens, in urine of women on various habitural diets
4. Excretion of the lignans enterolactone and enterodiol and of equol in omnivorous and vegetarian postmenopausal women and in women with breast cancer
5. Quantitative determination of lignans and isoflavonoids in plasma of omnivorous and vegetarian women by isotope dilution gas-chromatography mass-spectrometry
6. Soybean phytoestrogen intake and cancer risk
7. Urinary excretion of lignans and isoflavonoid phytoestrogens in Japanese men and women consuming traditional Japanese diet
8. Folate metabolism and requirements
9. Polymorphisms of methylenetetrahydrofolate reductase and other enzymes, metabolic significance, risks and impact on folate requirement
10. Dietary intervention study to assess estrogenicity of dietary soy among postmenopausal women
11. Phytoestrogens and breast cancer
12. Qualitative relationship of dietary and plasma carotenoids in human beings
13. A quality assurance program for the measurement of capillary blood cholesterol levels in private paediatric practices The Children's Health Project
14. Biochemical evaluation of iodine status
15. Prostate cancer and prediagnostic levels of serum vitamin D metabolites (Maryland, United States)
16. Low-dose folic acid supplementation decreases plasma homocysteine concentrations, a randomized trial
17. Dietary folate from vegetables and citrus fruit decreases plasma homocysteine concentrations in humans in a dietary controlled trial
18. Iodide excretion before and after revision of goiter prophylaxis (Dutch nutrition surveillance system)
19. Predictors of dietary heterocyclic amine intake in three prospective cohorts
20. Biological effects of a diet of soy protein rich in isoflavones on the menstrual cycle of premenopausal women
21. Usual dietary consumption of soy foods and its correlation with the excretion rate of isoflavonoids in overnight urine samples among Chinese women in Shanghai
22. Iodine
23. Methylene bis (2-chloroaniline) (MbOCA), towards a biological monitoring guidance value
24. Seasonal variation in vitamin D, vitamin D-binding protein and dehydroepiandrosterone. Risk of prostate cancer in black and white men
25. Vitamin D and prostate cancer, a prediagnostic study with stored sera
26. Nutritional attributes of traditional flaxseed in healthy young adults
27. Folic acid in the prevention of neural tube defects
28. Folate intake in Europe, recommended, actual and desired intake
29. External quality assessment scheme in Belgium. Heavy metal analyses
30. Neural tube defects in Jamaica following Hurricane Gilbert
31. Techniques for measuring urinary iodine - An update
32. Effect of sample storage on quantitation of lipoprotein(a) by an enzyme-linked immunosorbent assay
33. Embryonic folate metabolism and mouse neural tube defects
34. High-performance liquid chromatographic assay of isoflavonoids and coumestrol from human urine
35. Saliva-based HIV-antibody testing in Thailand
36. 32P-postlabelling
37. Human metallothionein gene expression determined by quantitative reverse transcription-polymerase chain reaction as a biomarker of cadmium exposure
38. Circulating vitamin D metabolites in relation to subsequent development of prostate cancer
39. Meat, cooking methods and colorectal cancer, a case referent study in Stockholm
40. Quality control of biomarker measurements in epidemiology
41. Mutations in the p53 tumor suppressor gene, clues to cancer etiology and molecular pathogenesis
42. Results of an international round robin for serum and whole-blood folate
43. Geographic patterns of prostate cancer mortality. Evidence for a protective effect of ultraviolet radiation
44. 12
45. Soybean phytoestrogen intake and cancer risk
46. The iodine deficiency disorders, their nature and prevention
47. The use and interpretation of assays for vitamin D and its metabolites
48. Urinary phytoestrogen levels in young women from a multiethnic population
49. Phytoestrogens and human health effects, weighing up the current evidence
50. Bioavailability of iodine
51. Molecular epidemiology of human cancer, contribution of mutation spectra studies of tumour suppressor genes
52. Urinary isoflavonoid phytoestrogen and lignan excretion after consumption of fermented and unfermented soy products
53. Cancer incidence in five continents
54. Association of prostate cancer risk with genetic polymorphisms in vitamin D receptor and androgen receptor
55. Phyto-oestrogens and breast cancer. Authors reply
56. Homocysteine increases as folate decreases in plasma of healthy men during short-term dietary folate and methyl group restriction
57. Biochemical markers of dietary intake
58. Specific 5′-GGGA-3′→5′-GGA-3′ mutation of the Apc gene in rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
59. Urinary isoflavonoid excretion in humans is dose dependent at low to moderate levels of soy-protein consumption
60. Stability of vitamins A, C and E, carotenoids, lipids and testosterone in whole blood stored at 4°C and 24 hours before separation of serum and plasma
61. Plasma and urinary kinetics of the isoflavones daidzein and genistein after a single soy meal in humans
62. Maternal plasma folate and vitamin B12 are independent risk factors for neural tube defects
63. Urinary lignan and isoflavonoid excretion in men and women consuming vegetable and soy diets
64. Effects of cooking time and temperature on the heterocyclic amine content of fried-beef patties
65. Future of dietary exposure assessment
66. Lycopene and myocardial infarction risk in the EURAMIC study
67. Resveratrol, a phytoestrogen found in red wine. A possible explanation for the conundrum of the French paradox?
68. 14C folic acid, with observations on the effect of diphenylhydantoin administration
69. Cloning a novel estrogen receptor expressed in rat prostate and ovary
70. Review. Iodine deficiency disorders and endomic goitre
71. Urinary lignan and isoflavonoid excretion in premenopausal women consuming flaxseed powder
72. Sample collection, processing and storage
73. Rapid metabolic phenotypes for acetyltransferase and cytochrome P4501A2 and putative exposure to food-borne heterocyclic amines increase the risk for colorectal cancer or polyps
74. Cancer risk of heterocyclic amines in cooked foods, an analysis and implications for research
75. Preventing neural tube defects, the importance of periconceptional folic acid supplements
76. Sex and long-term soy diets affect the metabolism and excretion of soy isoflavones in humans
77. Altered time course of urinary daidzein and genistein excretion during chronic soya diet in healthy male subjects
78. Altered kinetics and extent of urinary daidzein and genistein excretion in women during chronic soya exposure
79. Intra- and interindividual variability in systemic exposure in humans to 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline and 2-amino-3,8-dimethylimidazo[4,5-b]pyridine, carcinogens present in cooked beef
80. Vitamin D receptor polymorphisms, circulating vitamin D metabolites and risk of prostate cancer in United States physicians
81. Biological effects of phytoestrogens
82. Phytoestrogen content in foods
83. Associations of plasma carotenoid concentrations and dietary intake of specific carotenoids in samples of two prospective cohort studies using a new carotenoid database
84. Homocysteine metabolism in pregnancies complicated by neural-tube defects
85. Homocysteine and neural tube defects
86. Effects of a soya milk supplement on oxidative DNA damage in men a pilot study
87. Measurement and metabolism of isoflavonoids and lignans in the human male
88. Prevention of neural tube defects. Results of the Medical Research Council vitamin study
89. Human metabolism of mammalian lignan precursors in raw and processed flaxseed
90. Controlled dietary folate affects folate status in nonpregnant women
91. Cancer statistics 1996
92. Molecular epidemiology, insights into cancer susceptibility, risk assessment and prevention
93. The Malmo biological bank
94. Quality control program for storage of biologically banked blood specimens in the Malmo diet and cancer study
95. Feasibility and quality of biological banking of human normal and tumour tissue specimens as sources of DNA for the malmo diet and cancer study
96. Naturally occurring oestrogens in foods - A review
97. Day-to-day and within-day variation in urinary excretion
98. Phytoestrogen content of foods - A compendium of literature values
99. Nutrition and cancer, background and rationale of the European Prospective Investigation into Cancer and Nutrition (EPIC)
100. Identifiability of food components for cancer chemoprevention
101. Periconceptional folate and neural tube defects
102. Isoflavonoid levels in spot urine are associated with frequency of dietary soy intake in a population-based sample of middle-aged and older Chinese in Singapore
103. Phytoestrogens, the biochemistry, physiology, and implications for human health of soy isoflavones
104. Folate chemistry and metabolism
105. Lower levels of urinary 2-amino-3,8-dimethylimidazo[4,5-f]-quinoxaline (MeIQx) in humans with higher CYP1A2 activity
106. The epidemiology of neural tube defects. A review of dietary intake and related factors as etiologic agents
107. Influence of soybean processing, habitual diet, and soy dose on urinary isoflavonoid excretion
108. Further experience of vitamin supplementation for prevention of neural tube defect recurrences
109. Vitamin deficiencies and neural tube defects
110. Possible prevention of neural-tube defects by periconceptional vitamin supplementation
111. Uptake of lycopene and its geometrical isomers is greater from heat-processed than from unprocessed tomato juice in humans
112. Iodine
113. Relative abundance of organochlorine pesticides and polychlorinated biphenyls in adipose tissue and serum of women in Long Island, New York
114. Kinetic modeling of folate metabolism through use of chronic administration of deuterium-labeled folic acid in men
115. Differences between plasma and adipose tissue biomarkers of carotenoids and tocopherols
116. Association of prostate cancer with vitamin D receptor gene polymorphism
117. Potential health benefits of dietary phytoestrogens. A review of the clinical, epidemiological, and mechanistic evidence
118. Iodine status of New Zealand residents as assessed by urinary iodine excretion and thyroid hormones
119. An evaluation of urinary measures of iodine and selenium status
120. Presence of N2-(dG-C8-MelQx) in human tissues
121. Plasma homocysteine, a risk factor for cardiovascular disease, is lowered by physiological doses of folic acid
122. Pharmacokinetics of soybean isoflavones in plasma, urine and feces of men after ingestion of 60 g braked soybean powder (Kinako)
123. Periconceptional folic acid exposure and risk of occurrent neural tube defects
124. Laboratory process specifications for assuring quality in the US National Cholesterol Education Program
125. Carcinogen-DNA and carcinogen-protein adducts in molecular epidemiology, IARC Scientific Publication No. 142
126. Dietary intake of aflatoxins and the level of albumin bound aflatoxin in peripheral blood in The Gambia, West Africa
127. Bioavailability of soybean isoflavones depends upon gut microflora in women
128. Daidzein is a more bioavailable soymilk isoflavone than is genistein in adult women
129. Mutational spectra of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine(phip) at the Chinese hamsters hprt locus
130. Cantonese style salted fish as a cause of nasopharyngeal carcinoma, report of a case-control study in Hong Kong
131. Reliability of serum measurements of lignans and isoflavonoid phytoestrogens over a two-year period
132. Urinary disposition of soybean isoflavones daidzein, genistein and glycitein differs among humans with moderate fecal isoflavone degradation activity