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Volumn 8, Issue 5, 2001, Pages 235-239

Obesity, free fatty acids, and insulin resistance

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID;

EID: 0034813837     PISSN: 10683097     EISSN: None     Source Type: Journal    
DOI: 10.1097/00060793-200110000-00002     Document Type: Review
Times cited : (39)

References (75)
  • 3
    • 0025093498 scopus 로고
    • Inducement by fat feeding of basal hyperglycemia in rats with abnormal beta-cell function: Model for study of etiology and pathogenesis of NIDDM
    • (1990) Diabetes , vol.39 , pp. 226-223
    • Pascoe, W.S.1    Storlien, L.H.2
  • 10
    • 0029084869 scopus 로고
    • Effects of fat on glucose uptake and utilization in patients with non-insulin-dependent diabetes
    • (1995) J Clin Invest , vol.96 , pp. 1261-1268
    • Boden, G.1    Chen, X.2
  • 13
    • 0032829745 scopus 로고    scopus 로고
    • Overnight lowering of free fatty acids with acipimox improves insulin resistance and glucose tolerance in obese diabetic and non-diabetic subjects
    • (1999) Diabetes , vol.48 , pp. 1836-1841
    • Santomauro, A.1    Boden, G.2    Silva, M.3
  • 15
    • 0031014830 scopus 로고    scopus 로고
    • Role of fatty acids in the pathogenesis of insulin resistance and NIDDM
    • (1997) Diabetes , vol.46 , pp. 3-10
    • Boden, G.1
  • 18
    • 0026087478 scopus 로고
    • Influence of dietary fat composition on development of insulin resistance in rats: Relation to muscle triglyceride and ω-3 fatty acids in muscle phospholipid
    • (1991) Diabetes , vol.40 , pp. 280-289
    • Storlien, L.H.1    Jenks, A.B.2    Chisholm, D.J.3
  • 26
    • 0035405847 scopus 로고    scopus 로고
    • Effects of acute changes of plasma FFA on intramuscular fat content and insulin resistance in healthy subjects
    • (2001) Diabetes , vol.50 , pp. 1612-1617
    • Boden, G.1    Lebed, B.2    Schatz, M.3
  • 30
    • 0030219077 scopus 로고    scopus 로고
    • Design of the oxygen and substrate pathways. VI. Structural basis of intra-cellular substrate supply to mitochondria in muscle cell
    • (1996) J Exp Biol , vol.199 , pp. 1689-1697
    • Vock, R.1    Hoppeler, H.2    Claassen, H.3
  • 35
    • 0028267475 scopus 로고
    • Effect of fatty acids and their acyl-CoA esters on protein kinase C activity in fibroblasts: Possible implications in fatty acid oxidation defects
    • (1994) Biochim Biophys Acta , vol.1221 , pp. 66-72
    • Nesher, M.1    Boneh, A.2
  • 36
    • 0027418067 scopus 로고
    • Overexpression of protein kinase C isoenzymes alpha, beta I, gamma and epsilon in cells overexpressing the insulin receptor: Effects on receptor phosphorylation and signaling
    • (1993) J Biol Chem , vol.268 , pp. 6338-6347
    • Chin, J.E.1    Dickens, M.2    Tavare, J.M.3
  • 37
    • 0031465447 scopus 로고    scopus 로고
    • Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen-activated protein kinase
    • (1997) J Biol Chem , vol.272 , pp. 31400-31406
    • DeFea, K.1    Roth, R.A.2
  • 39
    • 0345086474 scopus 로고    scopus 로고
    • Free fatty acid-induced insulin resistance is associated with activation of protein kinase C θ and alterations in the insulin signaling cascade
    • (1999) Diabetes , vol.48 , pp. 1270-1274
    • Griffin, M.E.1    Marcucci, M.J.2    Cline, G.W.3
  • 41
    • 0031046187 scopus 로고    scopus 로고
    • The tissue concentration of UDP-N-acetylgluco-samine modulates the stimulatory effect of insulin on skeletal muscle glucose uptake
    • (1997) J Biol Chem , vol.272 , pp. 4889-4895
    • Hawkins, M.1    Angelov, I.2    Liu, R.3
  • 45
    • 0029948098 scopus 로고    scopus 로고
    • Effect of tumor necrosis factor-alpha on insulin action in cultured rat skeletal muscle cells
    • (1996) Endocrinology , vol.137 , pp. 2441-2446
    • Begum, N.1    Ragolia, L.2
  • 46
    • 0029906375 scopus 로고    scopus 로고
    • Effects of an engineered human anti-TNF-alpha antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM
    • (1996) Diabetes , vol.45 , pp. 881-885
    • Oefi, F.1    Hurel, S.2    Newkirk, J.3
  • 47
    • 0030864185 scopus 로고    scopus 로고
    • Targeted disruption of the tumor necrosis factor-alpha gene: Metabolic consequences in obese and nonobese mice
    • (1997) Diabetes , vol.46 , pp. 1526-1531
    • Ventre, J.1    Doebber, T.2    Wu, M.3
  • 53
    • 0019762341 scopus 로고
    • The effect of insulin on the disposal of intravenous glucose: Results from indirect calorimetry and hepatic and femoral venous catheterization
    • (1981) Diabetes , vol.30 , pp. 1000-1007
    • DeFronzo, R.A.1    Jacot, E.2    Jequier, E.3
  • 57
    • 0027368014 scopus 로고
    • Demonstration of a critical role for free fatty acids in mediating counterregulatory stimulation of gluconeogenesis and suppression of glucose utilization in humans
    • (1993) J Clin Invest , vol.92 , pp. 1617
    • Fanelli, C.1    Calderone, S.2    Epifano, L.3
  • 66
    • 0024995157 scopus 로고
    • A 48-hour lipid infusion in the rat time-dependently inhibits glucose-induced insulin secretion and β-cell oxidation through a process likely coupled to fatty acid oxidation
    • (1990) Endocrinology , vol.127 , pp. 1580-1589
    • Sako, Y.1    Grill, V.E.2
  • 67
    • 0028268936 scopus 로고
    • Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle
    • (1994) J Clin Invest , vol.93 , pp. 870-876
    • Zhou, Y.-P.1    Grill, V.E.2
  • 68
    • 0032030866 scopus 로고    scopus 로고
    • Chronic exposure to free fatty acids reduced pancreatic β cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation
    • (1998) J Clin Invest , vol.101 , pp. 1094-1101
    • Bollheimer, L.C.1    Skelly, R.H.2    Chester, M.W.3
  • 70
    • 0031716376 scopus 로고    scopus 로고
    • Acute lowering of plasma fatty acids lowers basal insulin secretion in diabetic and nondiabetic subjects
    • (1998) Diabetes , vol.47 , pp. 1609-1612
    • Boden, G.1    Chen, X.2    Iqbal, N.3
  • 72
    • 0024160877 scopus 로고
    • Role of insulin resistance in human disease
    • (1988) Diabetes , vol.37 , pp. 1595-1607
    • Reaven, G.M.1
  • 73
    • 0000246182 scopus 로고    scopus 로고
    • Free fatty acids (FFA), a link between obesity and insulin resistance
    • (1998) Front Biosci , vol.3
    • Boden, G.1
  • 74
    • 0034852786 scopus 로고    scopus 로고
    • Free fatty acids - The link between obesity and isulin resistance
    • (2001) Endocr Pract , vol.7 , pp. 44-51
    • Boden, G.1
  • 75
    • 0033009463 scopus 로고    scopus 로고
    • Effects of fatty acids and ketone bodies on basal insulin secretion in type 2 diabetes
    • (1999) Diabetes , vol.48 , pp. 577-583
    • Boden, G.1    Chen, X.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.