Cell apoptosis induced by carcinogenic metals

Molecular and Cellular Biochemistry

Volumn 222, Issue 1-2, 2001, Pages 183-188

  Chen, F ^a   Vallyathan, V ^a   Castranova, V ^a   Shi, X ^a  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

Author keywords

Apoptosis; Carcinogenesis; DNA damage; Metal; ROS

Indexed keywords

ARSENIC; CARCINOGEN; CHROMIUM; DNA; LIPID; METAL; PROTEIN; REACTIVE OXYGEN METABOLITE; VANADIUM;

APOPTOSIS; ARTICLE; CANCER; CELL DEATH; DNA DAMAGE; ENVIRONMENTAL EXPOSURE; HUMAN; INFLAMMATION; LIPID PEROXIDATION; MEDICAL DOCUMENTATION; MOUSE; NONHUMAN; OCCUPATIONAL EXPOSURE; PROTEIN MODIFICATION; REVIEW;

ANIMALS; APOPTOSIS; CARCINOGENS; DNA DAMAGE; HUMANS; METALS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 0034806639     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1017970330982     Document Type: Article

References (53)

1. Mitochondria and apoptosis
2. Death receptors: Signaling and modulation
3. The inhibitors of apoptosis (IAPs) and their emerging role in cancer
4. Bcl-2 family proteins
5. Mitochondrial aging: Open questions
6. Apoptosis. The little devil of death
7. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
8. Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
9. Molecular characterization of mitochondrial apoptosis-inducing factor
10. Apoptosis is the mode of cell death caused by carcinogenic chromium
11. Induction of internucleosomal DNA fragmentation by carcinogenic chromate: Relationship to DNA damage, genotoxicity, and inhibition of macromolecular synthesis
12. Sensitive quantitation of chromium-DNA adducts by inductively coupled plasma mass spectrometry with a direct injection high-efficiency nebulizer
13. Molecular basis for effects of carcinogenic heavy metals on inducible gene expression
14. Antioxidant properties of pyrrolidine dithiocarbamate and its protection against Cr(VI)-induced DNA strand breakage
15. The role of hydroxyl radical as a messenger in Cr (VI)-induced p53 activation
16. Chromium (VI) induces p53-dependent apoptosis in diploid human lung and mouse dermal fibroblasts
17. p53 regulation by post translational modification and nuclear retention in response to diverse stresses
18. Regulation of p53 function and stability by phosphorylation
19. Phosphorylation of the tumor suppressor protein p53 by mitogen-activated protein kinases
20. p53 is phosphorylated in vitro and in vivo by an ultraviolet radiation-induced protein kinase characteristic of the c-Jun kinase, JNK1
21. Participation of MAP kinase p38 and IkappaB kinase in chromium (VI)-induced NF-kappaB and AP-1 activation
22. Redox modulation of p53 conformation and sequence-specific DNA binding in vitro
23. Redox signalling and transition metals in the control of the p53 pathway
24. A model for p53-induced apoptosis
25. Roles for p53 in growth arrest and apoptosis: Putting on the brakes after genotoxic stress
26. ei24, a p53 response gene involved in growth suppression and apoptosis
27. Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
28. The role of superoxide radical in chromium (VI)-generated hydroxyl radical: The Cr(VI) Haber-Weiss cycle
29. Oxidative mechanisms in the toxicity of chromium and cadmium ions
30. Possible roles of nitric oxide and redox cell signaling in metal-induced toxicity and carcinogenesis: A review
31. Apoptosis and p53 induction in human lung fibroblasts exposed to chromium (VI): Effect of ascorbate and tocopherol
32. Global outlook on nutrition and the environment: Meeting the challenges of the next millennium
33. Arsenic mediates cell proliferation and gene expression in the bladder epithelium: Association with activating protein-1 transactivation
34. In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia:As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation alpha/PML proteins
35. Arsenic trioxide-induced apoptosis and differentiation are associated respectively with mitochondrial transmembrane potential collapse and retinoic acid signaling pathways in acute promyelocytic leukemia
36. Arsenite induces apoptosis via a direct effect on the mitochondrial permeability transition pore
37. Arsenic induces apoptosis through a c-Jun NH2-terminal kinase-dependent, p53-independent pathway
38. Arsenite induces apoptosis in Chinese hamster ovary cells by generation of reactive oxygen species
39. Involvement of reactive oxygen species and caspase 3 activation in arsenite-induced apoptosis
40. Inhibition of arsenite-induced apoptosis and AP-1 activity by epigallocatechin-3-gallate and theaflavins
41. Role of reactive oxygen intermediates in activation-induced CD95 (APO-1/Fas) ligand expression
42. Oxidative stress and hypoxia/reoxygenation trigger CD95(APO-1/Fas) ligand expression in microglial cells
43. Reactive oxygen intermediates are involved in the induction of CD95 ligand mRNA expression by cytostatic drugs in hepatoma cells
44. Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization
45. Pyrrolidine dithiocarbamate, a potent inhibitor of nuclear factor kappa B (NF-kappa B) activation, prevents apoptosis in human promyelocytic leukemia HL-60 cells and thymocytes
46. Opposite effect of NF-kB and c-Jun-N-terminal kinase on p53-independent GADD45 induction by arsenite
47. Vanadium
48. Induction of neoplastic progression in Syrian hamster embryo cells treated with protein phosphatase inhibitors
49. The intensity of vanadium (V)-induced cytotoxicity and morphological transformation in BALB/3T3 cells is dependent on glutathione-mediated bioreduction to vanadium (IV)
50. Inhibition of tyrosine phosphatases induces apoptosis independent from the CD95 system
51. Vanadate induces p53 transactivation through hydrogen peroxide and causes apoptosis
52. Sodium vanadate inhibits apoptosis in malignant glioma cells: A role for Akt/PKB
53. Regulation of intestinal tyrosine phosphorylation and programmed cell death by peroxovanadate