Inhibition of arsenite-induced apoptosis and AP-1 activity by epigallocatechin-3-gallate and theaflavins

Journal of Environmental Pathology, Toxicology and Oncology

Volumn 19, Issue 3, 2000, Pages 287-295

  Chen, N Y ^a   Ma, W Y ^a   Yang, C S ^a   Dong, Z ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Apoptosis; Arsenite; MAP kinases; Tea polyphenols

Indexed keywords

ARSENIC TRIOXIDE; EPIGALLOCATECHIN GALLATE; POLYPHENOL DERIVATIVE; SYNAPTOPHYSIN; TRANSCRIPTION FACTOR AP 1;

ANIMAL CELL; APOPTOSIS; ARTICLE; DRUG EFFECT; DRUG SCREENING; ENZYME ACTIVITY; MOUSE; NONHUMAN; PHYTOCHEMISTRY; PHYTOTHERAPY; PRIORITY JOURNAL; TEA;

ANIMALS; ANTIMUTAGENIC AGENTS; ANTIOXIDANTS; APOPTOSIS; ARSENITES; BIFLAVONOIDS; CATECHIN; CELLS, CULTURED; DNA; DRUG INTERACTIONS; FLAVONOIDS; IMIDAZOLES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHENOLS; PHOSPHORYLATION; POLYMERS; PYRIDINES; SKIN; TEA; TERATOGENS; TRANSCRIPTION FACTOR AP-1;

EID: 0033850570     PISSN: 07318898     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Toxic effects of metals
2. Arsenic and cancer
3. The absorption of arsenic and its relation to carcinoma
4. Arsenic can mediate skin neoplasia by chronic stimulation of keratinocyte-derived growth factors
5. Pesticides and cancer
6. Arsenic - New life for an old potion
7. The tumor promoter arsenite stimulates AP-1 activity by inhibiting a JNK phosphatase
8. Differential activation of ERK, JNK/SAPK, and p38/CSBP/RK MAP kinase family members during the cellular response to arsenite
9. The stress inducer arsenite activates mitogen-activated protein kinases extracellular signal regulated kinases 1 and 2 via a MAPK kinase 6/p38-dependent pathway
10. Arsenic targets tubulins to induce apoptosis in myeloid leukemia cells
11. Arsenic induces apoptosis in B-cell leukaemic cell lines in vitro: Activation of caspases and down-regulation of Bcl-2 protein
12. Inhibition of phorbol ester tumor promoter 12-O-tetradecanoylphorbol-13-acetate-caused inflammatory responses in SENCAR mouse skin by black tea polyphenols
13. Inhibition of carcinogenesis by tea
14. Characterization of early pulmonary hyperproliferation and tumor progression and their inhibition by black tea in a 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis model with A/J mice
15. Inhibition of tumor promoter-induced activator protein 1 activation and cell transformation by tea polyphenols, (-)-epigallocatechin gallate, and theaflavins
16. The block of carcinogenesis by vegetable, tea
17. Inhibitory effects of perillyl alcohol on UVB-induced murine skin cancer and AP-1 transactivation
18. Proteinase inhibitors I and II from potatoes specifically block UV-induced activator protein-1 activation through a pathway that is independent of extracellular signal-regulated kinases, c-Jun N-terminal kinases, and p38 kinase
19. Inhibition of activator protein 1 activity and neoplastic transformation by aspirin
20. Inhibition of tumor promoter-induced transformation by retinoids that transrepress AP-1 without transactivating retinoic acid response element
21. Activation of p53 transcriptional activity by 1,10-phenanthroline, a metal chelator, and redox-sensitive compound
22. Translocation of protein kinase C epsilon and protein kinase C delta to membrane is required for ultraviolet B-induced activation of mitogen-activated protein kinases and apoptosis
23. Arsenic induces apoptosis through a c-Jun NH2-terminal kinase-dependent, p53-independent pathway
24. Activation of MAP kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
25. Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II
26. Regulation and function of the JNK subgroup of MAP kinases
27. p38 kinase mediates UV-induced phosphorylation of p53 protein at serine 389
28. Metal carcinogenesis: Mechanistic implications