메뉴 건너뛰기




Volumn 36, Issue 2-3, 2001, Pages 222-229

Sustained delivery of GDNF: Towards a treatment for Parkinson's disease

Author keywords

Animal model; Cell encapsulation; Cell transplantation; Clinical trial; Gene therapy; Glial cell line derived neurotrophic factor; Neurotrophic factor; Parkinson's disease; Viral vectors

Indexed keywords

DOPAMINE; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; RECOMBINANT PROTEIN; VIRUS VECTOR;

EID: 0034750770     PISSN: 01650173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0173(01)00098-4     Document Type: Review
Times cited : (59)

References (60)
  • 1
    • 2442646665 scopus 로고    scopus 로고
    • A double-blind placebo-controlled clinical trial of subcutaneous recombinant human ciliary neurotrophic factor (rHCNTF) in amyotrophic lateral sclerosis
    • (1996) Neurology , vol.46 , Issue.5 , pp. 1244-1249
  • 8
    • 0028104614 scopus 로고
    • Ethical guidelines for the use of human embryonic or fetal tissue for experimental and clinical neurotransplantation and research
    • Network of European CNS Transplantation and Restoration (NECTAR)
    • (1994) J. Neurol. , vol.242 , Issue.1 , pp. 1-13
    • Boer, G.J.1
  • 21
    • 0031678831 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor (GDNF): A drug candidate for the treatment of Parkinson's disease
    • (1998) J. Neurol. , vol.245 , Issue.11 SUPPL. 3
    • Grondin, R.1    Gash, D.M.2
  • 23
    • 0031899172 scopus 로고    scopus 로고
    • Oxidative mechanisms in nigral cell death in Parkinson's disease
    • (1998) Mov. Disord. , vol.13 , Issue.SUPPL. 1 , pp. 24-34
    • Jenner, P.1
  • 26
    • 0033773237 scopus 로고    scopus 로고
    • Preservation of a functional nigrostriatal dopamine pathway by GDNF in the intrastriatal 6-OHDA lesion model depends on the site of administration of the trophic factor
    • (2000) Eur. J. Neurosci. , vol.12 , Issue.11 , pp. 3871-3882
    • Kirik, D.1    Rosenblad, C.2    Bjorklund, A.3
  • 27
    • 0034659835 scopus 로고    scopus 로고
    • Long-term rAAV-mediated gene transfer of GDNF in the rat Parkinson's model: Intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned nigrostriatal system
    • (2000) J. Neurosci. , vol.20 , Issue.12 , pp. 4686-4700
    • Kirik, D.1    Rosenblad, C.2    Bjorklund, A.3    Mandel, R.J.4
  • 37
    • 0031920326 scopus 로고    scopus 로고
    • Update on fetal transplantation: The Swedish experience
    • (1998) Mov. Disord. , vol.13 , Issue.SUPPL. 1 , pp. 83-87
    • Lindvall, O.1
  • 40
    • 0031456051 scopus 로고    scopus 로고
    • Midbrain injection of recombinant adeno-associated virus encoding rat glial cell line-derived neurotrophic factor protects nigral neurons in a progressive 6-hydroxydopamine-induced degeneration model of Parkinson's disease in rats
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , Issue.25 , pp. 14083-14088
    • Mandel, R.J.1    Spratt, S.K.2    Snyder, R.O.3    Leff, S.E.4
  • 48
    • 0033082385 scopus 로고    scopus 로고
    • The GDNF protein family: Gene ablation studies reveal what they really do and how
    • (1999) Neuron , vol.22 , Issue.2 , pp. 201-203
    • Rosenthal, A.1
  • 52
    • 0032457981 scopus 로고    scopus 로고
    • Growth/differentiation factor 5 and glial cell line-derived neurotrophic factor enhance survival and function of dopaminergic grafts in a rat model of Parkinson's disease
    • (1998) Eur. J. Neurosci. , vol.10 , Issue.12 , pp. 3681-3688
    • Sullivan, A.M.1    Pohl, J.2    Blunt, S.B.3
  • 54
    • 0033972740 scopus 로고    scopus 로고
    • Lentiviral vectors: Turning a deadly foe into a therapeutic agent
    • (2000) Gene Ther. , vol.7 , Issue.1 , pp. 20-23
    • Trono, D.1
  • 55
    • 0030915959 scopus 로고    scopus 로고
    • Complementary and overlapping expression of glial cell line-derived neurotrophic factor (GDNF), c-ret proto-oncogene, and GDNF receptor-alpha indicates multiple mechanisms of trophic actions in the adult rat CNS
    • (1997) J. Neurosci. , vol.17 , Issue.10 , pp. 3554-3567
    • Trupp, M.1    Belluardo, N.2    Funakoshi, H.3    Ibanez, C.F.4
  • 58
    • 0028854836 scopus 로고
    • In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons
    • see comments
    • (1995) Nature , vol.373 , Issue.6512 , pp. 341-344
    • Yan, Q.1    Matheson, C.2    Lopez, O.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.