Identification of the protonated oxygenic ligands of ribonucleotide reductase intermediate X by Q-band 1,2H CW and pulsed ENDOR

Journal of the American Chemical Society

Volumn 119, Issue 41, 1997, Pages 9816-9824

  Willems, Jean Paul ^a   Lee, Hong In ^a   Burdi, Doug ^b   Doan, Peter E ^a   Stubbe, Joanne ^b   Hoffman, Brian M ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIGAND; RIBONUCLEOTIDE REDUCTASE;

ARTICLE; CALCULATION; CHEMICAL REACTION; DRUG IDENTIFICATION; ENZYME ANALYSIS; MEASUREMENT; PROTON TRANSPORT;

EID: 0030691770     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9709942     Document Type: Article

References (47)

1. Feig, A. L.; Lippard, S. J. Chem. Rev. 1994, 94, 759-805.
2. Wallar, B. J.; Lipscomb, J. D. Chem. Rev. 1996, 96, 2625-2657.
3. Shiemke, A. K.; Sanders-Loehr, T. M.; Sanders-Loehr, J. J. Am. Chem. Soc. 1986, 108, 2437-2443.
4. Rosenzweig, A. C.; Nordlund, P.; Takahara, P. M.; Frederick, C. A.; Lippard, S. J. Chem. Biol. 1995, 2, 409-418.
5. Logan, D. T.; Su, X.-D.; Åberg, A.; Regnström, K.; Hajdu, J.; Eklund, H.; Nordlund, P. Structure 1996, 4, 1053-1064.
6. Holmes, M. A.; LeTrong, I.; Turley, S.; Sicker, L. C.; Stenkamp, K. E. J. Mol. Biol. 1991, 218, 583-593.
7. Kiu, K. E.; Valentine, A. M.; Wang, D.; Huynh, B. H.; Edmondson, D. E.; Salifoglou, A.; Lippard, S. J. J. Am. Chem. Soc. 1995, 117, 10174-10185.
8. Lee, S.-K.; Nesheim, J. C.; Lipscomb, J. D. J. Biol. Chem. 1993, 268, 21569-21577.
9. Liu, K. E.; Wang, D.; Huynh, B. H.; Edmondson, D. E.; Salifoglou, A.; Lippard, S. J. J. Am. Chem. Soc. 1994, 776, 7465-7466.
10. Liu, K. E.; Valentine, A. M.; Qiu, D.; Edmondson, D. E.; Appelman, E. H.; Spiro, T. G.; Lippard, S. J. J. Am. Chem. Soc. 1995, 117, 4997-4998.
11. Lee, S.-K.; Fox, B. G.; Froland, W. A.; Lipscomb, J. D.; Münck, E. J. Am. Chem. Soc. 1993, 115, 6450-6451.
12. Shu, L.; Nesheim, J. C.; Kauffmann, K.; Münck, E.; Lipscomb, J. D.; Que, L., Jr. Science 1997, 275, 515-518.
13. Atkin, C. L.; Thelander, L.; Reichard, P.; Lang, G. J. Biol Chem. 1973, 248, 7464-7472.
14. Larsson, Å.; Sjöberg, B.-M. EMBO J. 1986, 5, 2037-2040.
15. Bollinger, J. M., Jr.; Edmondson, D. E.; Huynh, B. H.; Filley, J.; Norton, J. R.; Stubbe, J. Science 1991, 253, 292-298.
16. Bollinger, J. M., Jr.; Tong, W. H.; Ravi, N.; Huynh, B. H.; Edmondson, D. E.; Stubbe, J. J. Am. Chem. Soc. 1994, 116, 8015-8023.
17. Tong, W. H. Ph.D. Thesis, Massachusetts Institute of Technology, 1996.
18. Riggs-Gelasco, P.; Shu, L.; Chen, S.; Burdi, D.; Huynh, B. H.; Que, L. J.; Stubbe, J. J. Am. Chem. Soc., submitted.
19. Abragam, A.; Bleaney, B. Electron Paramagnetic Resonance of Transition Ions, 2nd ed.; Clarendon Press: Oxford, 1970.
20. (a) Sturgeon, B. E.; Burdi, D.; Chen, S.; Huynh, B.-H.; Edmondson, D. E.; Stubb, J.; Huffman, B. M. J. Am, Chem. Soc, 1996, 118, 7551-7557.
21. (b) Burdi, D.; Sturgeon, B. E.; Tong, W. H.; Stubbe, J.; Hoffman, B. M. J. Am. Chem. Soc. 1996, 118, 281-282.
22. Ravi, N.; Bollinger, J. M., Jr.; Huynh, B. H.; Edmondson, D. E.; Stubbe, J. J. Am. Chem. Soc. 1994, 116, 8007-8014.
23. Doan, P. E.; Fan, C.; Hoffman, B. M. J. Am. Chem. Soc. 1994 116, 1033-1041.
24. DeRose, V. J.; Liu, K. E.; Lippard, S. J.; Hoffman, B. M. J. Am. chem. Soc. 1996, 118, 121-134.
25. Veselov, A.; Scholes, C. P. Inorg. Chem. 1996, 35, 3702-3705.
26. Salowe, S. P. Ph.D. Thesis, University of Wisconsin, 1987.
27. Thelander, L. J. Biol. Chem. 1973, 248, 4591-4601.
28. Sturgeon, B. E.; Burdi, D.; Chen, S.; Huynh, B.-H.; Edmondson, D. E.; Stubbe, J.; Huffman, B. M. J. Am. Chem. Soc. 1996, 118, 7551-7557.
29. Glasoe, P. K.; Long, F. A. J. Phys. Chem. 1960, 64, 188-190.
30. Werst, M. M.; Davoust, C. E.; Huffman, B. M. J. Am. Chem. Soc. 1991, 113, 1533-1538.
31. Davoust, C. E.; Doan, P. E.; Hoffman, B. M. J. Magn. Reson., A 1996, 779, 38-44.
32. DeRose, V. J.; Huffman, B. M. Methods Enzymol. 1995, 246, 554-589.
33. Gemperle, C.; Schweiger, A. Chem. Rev. 1991, 97, 1481-1505.
34. Davies, E. R. Phys. Lett. 1974, 47A, 1-2.
35. Fan, C.; Doan, P. E.; Davoust, C. E.; Hoffman, B. M. J. Magn. Reson. 1992, 95, 62-72.
36. Mims, W. B. Proc. R. Soc. London 1965, 283, 452-457.
37. Doan, P. E.; Hoffman, B. M. Chem. Phys. Lett. 1997, 269, 208-214.
38. Hoffman, B. M. Acc. Chem. Res. 1991, 24, 164-170.
39. Hoffman, B. M.; DeRose, V. J.; Doan, P. E.; Gurbiel, R. J.; Houseman, A. L. P.; Telser, J. In EMR of Paramagnetic Molecules; Berliner. L. J., Reuben, J., Eds.; Biological Magnetic Resonance 13; Plenum Press: New York, 1993; pp 151-218.
40. Fann, Y.-C.; Ong, J.; Nocek, J. M.; Hoffman, B. M. J. Am. Chem. Soc. 1995, 117, 6109-6116.
41. Fann, Y. C.; Gerber, N. C.; Osmulski, P. A.; Hager, L. P.; Sligar, S.G.; Hoffman, B. M. J. Am. Chem. Soc. 1994, 116, 5989-5990.
42. The relative orientations of the hyperfine and quadrupole tensors for each protonic species depend on the exact orientation of the water, with indistinguishable results for an appreciable range of choices; such details are irrelevant to this report.
43. Hendrich, M. P.; Fox, B. G.; Andersson, K. K.; Debrunner, P. G.; Lipscomb, J. D. J. Biol Chem. 1992, 267, 261-269.
44. Edmonds, D. T. Phys. Lett. 1977, C29, 233-290.
45. True, A. E.; Nelson, M. J.; Venters, R. A.; Orme-Johnson, W. H.; Hoffman, B. M. J. Am. Chem. Soc. 1988, 110, 1935-1943.
46. Note Added in Proof: The problem of a proton dipole-coupled to a dinuclear center has been treated recently by others, (a) Randall, D. W.; Gelasco, A.; Caudle, M. T.; Pecoraro, V. L.; Britt, R. D. J. Am. Chem. Soc. 1997, 119, 4481-4491. (b) Fiege, R.; Zweygart, W.; Bittl, R.; Adir, N.; Renger, G.; Lubitz, W. Photosynthesis Res. 1996, 48, 227-237.
47. Note Added in Proof: The problem of a proton dipole-coupled to a dinuclear center has been treated recently by others, (a) Randall, D. W.; Gelasco, A.; Caudle, M. T.; Pecoraro, V. L.; Britt, R. D. J. Am. Chem. Soc. 1997, 119, 4481-4491. (b) Fiege, R.; Zweygart, W.; Bittl, R.; Adir, N.; Renger, G.; Lubitz, W. Photosynthesis Res. 1996, 48, 227-237.