The activation of p38 and apoptosis by the inhibition of Erk is antagonized by the phosphoinositide 3-kinase/Akt pathway

Journal of Biological Chemistry

Volumn 273, Issue 17, 1998, Pages 10792-10797

  Berra, Edurne ^a   Diaz Meco, María T ^a   Moscat, Jorge ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CROSS LINKING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENETIC TRANSFECTION; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; APOPTOSIS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CASPASE 3; CASPASES; CYSTEINE ENDOPEPTIDASES; ENZYME ACTIVATION; HELA CELLS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION;

EID: 0032562682     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.17.10792     Document Type: Article

References (39)

1. Fanger, G. R., Gerwins, P., Widmann, C., Jarpe, M. B., and Johnson, G. L. (1997) Curr. Opin. Genet. Dev. 7, 67-74
2. Kyriakis, J. M., and Avruch, J. (1996) J. Biol. Chem. 271, 24313-24316
3. Verheij, M., Bose, R., Lin, X. H., Yao, B., Jarvis, W. D., Grant, S., Birrer, M. J., Szabo, E., Zon, L. I., Kyriakis, J. M., Haimovitz-Friedman, A., Fuks, Z., and Kolesnick, R. N. (1996) Nature 380, 75-79
4. Westwick, J. K., Bielawska, A. E., Dbaibo, G., Hannun, Y., and Brenner, D. A. (1995) J. Biol. Chem. 270, 22689-22692
5. Zanke, B. W., Boudreau, K., Rubie, E., Winnet, E., Tibbles, L. A., Zon, L., Kyriakis, J., Liu, F., and Woodgett, J. R. (1996) Curr. Biol. 6, 606-613
6. Yang, X., Khosravi-Far, R., Chang, H. Y., and Baltimore, D. (1997) Cell 89, 1067-1076
7. Xia, Z., Dickens, M., Raingeaud, J., Davis, R. J., and Greenberg, M. E. (1995) Science 270, 126-131
8. Berra, E., Municio, M. M., Sanz, L., Frutos, S., Diaz-Meco, M. T., and Moscat, J. (1997) Mol. Cell. Biol. 17, 4346-4354
9. Yang, D. D., Kuan, C., Whitmarsh, A. J., Rincon, M., Zheng, T. S., Davis, R. J., Rakic, P., and Flavell, R. A. (1997) Nature 389, 865-870
10. Liu, Z., Hsu, H., Goeddel, D. V., and Karin, M. (1996) Cell 87, 565-576
11. Canman, C. E., and Kastan, M. B. (1996) Nature 213-214
12. Gardner, A. M., and Johnson, G. L. (1996) J. Biol. Chem. 271, 14560-14566
13. Parrizas, M., Saltiel, A. R., and LeRoith, D. (1997) J. Biol. Chem. 272, 154-161
14. Yao, R., and Cooper, G. M. (1995) Science 267, 2003-2006
15. Kaufmann-Zeh, A., Rodriguez-Viciana, P., Ulrich, E., Gilbert, C., Coffer, P., Downward, J., and Evan, G. (1997) Nature 385, 544-548
16. Khwaja, A., Rodriguez-Viciana, P., Wennstrom, S., Warne, P. H., and Downward, J. (1997) EMBO J. 15, 2783-2793
17. Kulik, G. A., Klippel, A., and Weber, M. J. (1997) Mol. Cell. Biol. 17, 1595-1606
18. Dudek, H., Datta, S. R., Franke, T. F., Birnbaum, M. J., Yao, R., Cooper, G. M., Segal, R. A., Kaplan, D. R., and Greenber, M. E. (1997) Science 275, 661-665
19. Hemmings, B. A. (1997) Science 275, 628-630
20. Philpott, K. L., McCarthy, M. J., Klippel, A., and Rubin, L. L. (1997) J. Cell Biol. 139, 809-815
21. Diaz-Meco, M. T., Municio, M. M., Frutos, S., Sanchez, P., Lozano, J., Sanz, L., and Moscat, J. (1996) Cell 86, 777-786
22. Hueber, A. O., Zörnig, M., Lyon, D., Suda, T., Nagata, S., and Evan, G. I. (1997) Science 278, 1305-1309
23. Rehemtulla, A., Hamilton, C. A., Chinnaiyan, A. M., and Dixit, V. M. (1997) J. Biol. Chem. 272, 25783-25786
24. Reap, E. A., Roof, K., Maynor, K., Borrero, M., Booker, J., and Cohen, P. L. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 5750-5755
25. Chinnaiyan, A. M., Tepper, C. G., Seldin, M. F., O'Rourke, K., Kischkel, F. C., Hellbardt, S., Krammer, P. H., Peter, M. E., and Dixit, V. M. (1996) J. Biol. Chem. 271, 4961-4965
26. Muzio, M., Chinnaiyan, A. M., Kischkel, F. C., O'Rourke, K., Shevchenko, A., Ni, J., Scaffidi, C., Bretz, J. D., Zhang, M., Gentz, R., Mann, M., Krammer, P. H., Peter, M. E., and Dixit, V. M. (1996) Cell 85, 817-827
27. Hsu, H., Shu, H. B., Pan, M. G., and Goeddel, D. V. (1996) Cell 84, 299-308
28. Cuvillier, O., Pirianov, G., Kleuser, B., Vanek, P. G., Coso, O. A., Gutkind, J. S., and Spiegel, S. (1996) Nature 381, 800-803
29. Sells, S. F., Han, S., Muthukkumar, S., Maddiwar, N., Johnstone, R., Boghaert, E., Gillis, D., Liu, G., Nair, P., Monnig, S., Collini, P., Mattson, M. P., Sukhatme, V. P., Zimmer, S. G., Wood, D. P., McRoberts, J. W., Shi, Y., and Rangnekar, V. M. (1997) Mol. Cell. Biol. 17, 3823-3832
30. Akimoto, K., Takahashi, R., Moriya, S., Nishioka, N., Takayanagi, J., Kimura, K., Fukui, Y., Osada S-I., Mizuno, K., Hirai, S-I., Kazlauskas, A., and Ohno, S. (1996) EMBO J. 15, 788-798
31. Herrera-Velit, P., Knutson, K. L., and Reiner, E. N. (1997) J. Biol. Chem. 272, 16445-16452
32. Mendez, R., Kollmorgen, G., White, M. F., and Rhoads, R. E. (1997) Mol. Cell. Biol. 17, 5184-5192
33. Sontag, E., Sontag, J. M., and Garcia, A. (1997) EMBO J. 16, 5662-5671
34. Datta, S. R., Dudek, H., Tao, X., Masters, S., Fu, H., Gotoh, Y., and Greenberg, M. E. (1997) Cell 91, 231-241
35. Peso, L., Gonzalez-Garcia, M., Page, C., Herrera, R., and Nuñez, G. (1997) Science 278, 687-689
36. Golstein, P. (1997) Science 275, 1081-1082
37. Vaux, D. L. (1997) Cell 90, 389-390
38. Yuan, Z. M., Utsugisawa, T., Huang, Y., Ishiko, T., Nakada, S., Kharbanda, S., Weichselbaum, R., and Kufe, D. (1997) J. Biol. Chem. 272, 23485-23488
39. Cardone, M. H., Salvesen, G. S., Widmann, C., Johnson, G., and Frisch, S. M. (1997) Cell 90, 315-323