Acyl-hydrazide derivatives of a xanthine carboxylic congener (XCC) as selective antagonists at human A(2B) adenosine receptors

Drug Development Research

Volumn 47, Issue 4, 1999, Pages 178-188

  Kim, Yong Chul ^a   Karton, Yishai ^a,b   Ji, Xiao Duo ^a   Melman, Neli ^a   Linden, Joel ^c   Jacobson, Kenneth A ^a,d  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH   (Israel)

^c UNIVERSITY OF VIRGINIA   (United States)

^d NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Adenylyl cyclase; Alkylxanthines; G protein coupled receptors; Purines; Radioligand; Structure activity relationships

Indexed keywords

4 [2 [7 AMINO 2 (2 FURYL) 1,2,4 TRIAZOLO[2,3 A][1,3,5]TRIAZIN 5 YLAMINO]ETHYL]PHENOL; 8 (4 CARBOXYMETHOXYPHENYL) 1,3 DIPROPYLXANTHINE; 8 [4 [(CARBOXYMETHYL)OXY]PHENYL] 1,3 DI(N PROPYL)XANTHINE N,N CITRACONYLHYDRAZIDE; ADENOSINE A2B RECEPTOR; ADENOSINE RECEPTOR BLOCKING AGENT; ENPROFYLLINE; HYDRAZIDE DERIVATIVE; MRS 1595; UNCLASSIFIED DRUG;

ARTICLE; CELL LINE; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LIGAND BINDING; STRUCTURE ACTIVITY RELATION;

EID: 0032871686     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2299(199908)47:4<178::AID-DDR4>3.0.CO;2-L     Document Type: Article

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