메뉴 건너뛰기




Volumn 16, Issue 7, 1997, Pages 1695-1709

Induction of apoptosis by the transcription factor c-Jun

Author keywords

AP 1; Apoptosis; bcl 2; c jun; CED 3 related cysteine proteases; ICE

Indexed keywords

CYSTEINE PROTEINASE; CYSTEINE PROTEINASE INHIBITOR; ESTROGEN RECEPTOR; FODRIN; HYBRID PROTEIN; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 1BETA CONVERTING ENZYME INHIBITOR; LEUCINE ZIPPER PROTEIN; ONCOPROTEIN; PROTEIN BCL 2; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR;

EID: 0030998713     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.7.1695     Document Type: Article
Times cited : (403)

References (118)
  • 1
    • 0027729892 scopus 로고
    • High levels of c-rel expression are associated with programmed cell death in the developing avian embryo and in bone marrow cells in vitro
    • Abbadie,C., Kabrun,N., Bouali,F., Smaradova,J., Stéhelin,D., Vandenbunder,B. and Enrietto,P.J. (1993) High levels of c-rel expression are associated with programmed cell death in the developing avian embryo and in bone marrow cells in vitro. Cell, 75, 899-912.
    • (1993) Cell , vol.75 , pp. 899-912
    • Abbadie, C.1    Kabrun, N.2    Bouali, F.3    Smaradova, J.4    Stéhelin, D.5    Vandenbunder, B.6    Enrietto, P.J.7
  • 2
    • 0025720735 scopus 로고
    • The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation
    • Angel,P. and Karin,M. (1991) The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochim. Biophys. Acta, 1072, 129-157.
    • (1991) Biochim. Biophys. Acta , vol.1072 , pp. 129-157
    • Angel, P.1    Karin, M.2
  • 3
    • 0023355884 scopus 로고
    • 12-O-tetradecanoyl-phorbol-13-acetate induction of the human collagenase gene is mediated by an inducible enhancer element located in the 5′-flanking region
    • Angel,P., Baumann,I., Stein,B., Delius,H., Rahmsdorf,H.J. and Herrlich,P. (1987) 12-O-tetradecanoyl-phorbol-13-acetate induction of the human collagenase gene is mediated by an inducible enhancer element located in the 5′-flanking region. Mol. Cell Biol., 7, 2256-2266.
    • (1987) Mol. Cell Biol. , vol.7 , pp. 2256-2266
    • Angel, P.1    Baumann, I.2    Stein, B.3    Delius, H.4    Rahmsdorf, H.J.5    Herrlich, P.6
  • 4
    • 0028231893 scopus 로고
    • Apoptosis is inversely related to necrosis and determines net growth in tumors bearing constitutively expressed myc, ras and HPV oncogenes
    • Arends,M.J., McGregor,A.H. and Wyllie,A.H. (1994) Apoptosis is inversely related to necrosis and determines net growth in tumors bearing constitutively expressed myc, ras and HPV oncogenes. J. Pathol., 144, 1045-1057.
    • (1994) J. Pathol. , vol.144 , pp. 1045-1057
    • Arends, M.J.1    McGregor, A.H.2    Wyllie, A.H.3
  • 5
    • 0025062215 scopus 로고
    • Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen
    • Berry,M., Metzger,D. and Chambon,P. (1990) Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen. EMBO J., 9, 2811-2818.
    • (1990) EMBO J. , vol.9 , pp. 2811-2818
    • Berry, M.1    Metzger, D.2    Chambon, P.3
  • 6
    • 0026476483 scopus 로고
    • Granulocyte-macrophage colony-stimulating factor/interleukin-3 fusion protein (pIXY 321) enhances high-dose ara-C-induced programmed cell death or apoptosis in human myeloid leukemia cells
    • Bhalla,K., Tang,C., Ibrado,A.M., Grant,S., Tourkina,E., Halladay,C., Hughes,M., Mohoney,M.E. and Huang,Y. (1992) Granulocyte-macrophage colony-stimulating factor/interleukin-3 fusion protein (pIXY 321) enhances high-dose ara-C-induced programmed cell death or apoptosis in human myeloid leukemia cells, Blood, 80, 2883-2890.
    • (1992) Blood , vol.80 , pp. 2883-2890
    • Bhalla, K.1    Tang, C.2    Ibrado, A.M.3    Grant, S.4    Tourkina, E.5    Halladay, C.6    Hughes, M.7    Mohoney, M.E.8    Huang, Y.9
  • 7
    • 0025806587 scopus 로고
    • Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain
    • Binétruy,B., Smeal,T. and Karin,M. (1991) Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain. Nature, 351, 122-127.
    • (1991) Nature , vol.351 , pp. 122-127
    • Binétruy, B.1    Smeal, T.2    Karin, M.3
  • 8
    • 0023572209 scopus 로고
    • Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of the transcription factor AP-1
    • Bohmann,D., Bos,T.J., Admon,A., Nishimura,T., Vogt,P.K. and Tjian,R. (1987) Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of the transcription factor AP-1. Science, 238, 1386-1392.
    • (1987) Science , vol.238 , pp. 1386-1392
    • Bohmann, D.1    Bos, T.J.2    Admon, A.3    Nishimura, T.4    Vogt, P.K.5    Tjian, R.6
  • 9
    • 0025059554 scopus 로고
    • Efficient transformation of chicken embryo fibroblasts by c-Jun requires structural modification in coding and noncoding sequences
    • Bos,T.J., Monteclaro,F.S., Mitsunobu,F., Ball,A.R., Chang,C.H., Nishimura,T. and Vogt,P.K. (1990) Efficient transformation of chicken embryo fibroblasts by c-Jun requires structural modification in coding and noncoding sequences. Genes Dev., 4, 1677-1678.
    • (1990) Genes Dev. , vol.4 , pp. 1677-1678
    • Bos, T.J.1    Monteclaro, F.S.2    Mitsunobu, F.3    Ball, A.R.4    Chang, C.H.5    Nishimura, T.6    Vogt, P.K.7
  • 10
    • 0027055702 scopus 로고
    • Transcription factors JunB and c-Jun are selectively up-regulated and functionally implicated in fibrosarcoma development
    • Bossy-Wetzel.E., Bravo,R. and Hanahan,D. (1992) Transcription factors JunB and c-Jun are selectively up-regulated and functionally implicated in fibrosarcoma development. Genes Dev., 6, 2340-2351.
    • (1992) Genes Dev. , vol.6 , pp. 2340-2351
    • Bossy-WetzelE1    Bravo, R.2    Hanahan, D.3
  • 11
    • 0024503589 scopus 로고
    • Prolonged activation of 711/1 and collagenase genes by tumor necrosis factor-alpha
    • Brenner,D.A., O'Hara,M., Angel,P., Chojkier,M. and Karin,M. (1989) Prolonged activation of 711/1 and collagenase genes by tumor necrosis factor-alpha. Nature, 377, 661-663.
    • (1989) Nature , vol.377 , pp. 661-663
    • Brenner, D.A.1    O'Hara, M.2    Angel, P.3    Chojkier, M.4    Karin, M.5
  • 12
    • 0023805088 scopus 로고
    • Cascade induction of c-fos, c-myc and heat shock 70K transcripts during recession of the rat ventral prostate gland
    • Buttyan,R., Zakeri,Z., Lockshin,R. and Wolgemuth,D. (1988) Cascade induction of c-fos, c-myc and heat shock 70K transcripts during recession of the rat ventral prostate gland. Mol. Endocrinol., 2, 650-657.
    • (1988) Mol. Endocrinol. , vol.2 , pp. 650-657
    • Buttyan, R.1    Zakeri, Z.2    Lockshin, R.3    Wolgemuth, D.4
  • 13
    • 0025147733 scopus 로고
    • Overexpression of avian or mouse c-jun in primary chick embryo fibroblasts confers a partially transformed phenotype
    • Castellazzi,M., Dangy,J.-P., Mechta,F., Hirai,S.-I., Yaniv,M., Samarut,J., Lasschilly,A. and Brun,G. (1990) Overexpression of avian or mouse c-jun in primary chick embryo fibroblasts confers a partially transformed phenotype. Oncogene, 5, 1541-1547.
    • (1990) Oncogene , vol.5 , pp. 1541-1547
    • Castellazzi, M.1    Dangy, J.-P.2    Mechta, F.3    Hirai, S.-I.4    Yaniv, M.5    Samarut, J.6    Lasschilly, A.7    Brun, G.8
  • 14
    • 0026092486 scopus 로고
    • A potential role for c-jun in cell cycle progression through late G1 and S
    • Cater,R., Cosenza,S.C., Pena,A., Lipson,K. and Soprano,D.R. (1991) A potential role for c-jun in cell cycle progression through late G1 and S. Oncogene, 6, 229-235.
    • (1991) Oncogene , vol.6 , pp. 229-235
    • Cater, R.1    Cosenza, S.C.2    Pena, A.3    Lipson, K.4    Soprano, D.R.5
  • 15
    • 0028917923 scopus 로고
    • Bcl-2 blocks degranulation but not fas-based cell-mediated cytotoxicity
    • Chiu,V.K., Walsh,C.M., Lui,C.-C., Reed,J.C. and Clark,W.R. (1995) Bcl-2 blocks degranulation but not fas-based cell-mediated cytotoxicity. J. Immunol., 154, 2023-2032.
    • (1995) J. Immunol. , vol.154 , pp. 2023-2032
    • Chiu, V.K.1    Walsh, C.M.2    Lui, C.-C.3    Reed, J.C.4    Clark, W.R.5
  • 17
    • 0028301094 scopus 로고
    • p53 dependence of early apoptotic and proliferative responses within the mouse intestinal epithelium following γ-irradiation
    • Clarke,A.R., Gledhill,S.I., Hooper,L.M., Bird,C.C. and Wyllie,A.H. (1994) p53 dependence of early apoptotic and proliferative responses within the mouse intestinal epithelium following γ-irradiation. Oncogene, 9, 1767-1773.
    • (1994) Oncogene , vol.9 , pp. 1767-1773
    • Clarke, A.R.1    Gledhill, S.I.2    Hooper, L.M.3    Bird, C.C.4    Wyllie, A.H.5
  • 19
    • 0026645859 scopus 로고
    • Expression and involvement of c-fos and c-jun protooncogenes in programmed cell death induced by growth factor deprivation in lymphoid cell lines
    • Colotta,F., Polentarutti,N., Sironi,M. and Mantovani,A. (1992) Expression and involvement of c-fos and c-jun protooncogenes in programmed cell death induced by growth factor deprivation in lymphoid cell lines. J. Biol. Chem., 267, 18278-18283.
    • (1992) J. Biol. Chem. , vol.267 , pp. 18278-18283
    • Colotta, F.1    Polentarutti, N.2    Sironi, M.3    Mantovani, A.4
  • 21
    • 0028073283 scopus 로고
    • MAPKs: New JNK expands the group
    • Davis,R.J. (1994) MAPKs: new JNK expands the group. Trends Biochem. Sci., 19, 470-473.
    • (1994) Trends Biochem. Sci. , vol.19 , pp. 470-473
    • Davis, R.J.1
  • 22
    • 0031025688 scopus 로고    scopus 로고
    • Expression of the papillomavirus E2 protein in HeLa cells leads to apoptosis
    • Desaintes,C., Demeret,C., Goyat,S., Yaniv,M. and Thierry,F. (1997) Expression of the papillomavirus E2 protein in HeLa cells leads to apoptosis. EMBO J., 16, 504-514.
    • (1997) EMBO J. , vol.16 , pp. 504-514
    • Desaintes, C.1    Demeret, C.2    Goyat, S.3    Yaniv, M.4    Thierry, F.5
  • 23
    • 0026341905 scopus 로고
    • Rapid and preferential activation of the c-jun gene during the mammalian UV response
    • Devary,Y., Gottlieb,R.A., Lau,L.F. and Karin,M. (1991) Rapid and preferential activation of the c-jun gene during the mammalian UV response. Mol Cell. Biol., 11, 2804-2811.
    • (1991) Mol Cell. Biol. , vol.11 , pp. 2804-2811
    • Devary, Y.1    Gottlieb, R.A.2    Lau, L.F.3    Karin, M.4
  • 24
    • 0027483920 scopus 로고
    • Induction of apoptosis in cerebellar granule neurons by low potassium: Inhibition of death by insulin-like growth factor I and cAMP
    • D'Mello,S.R., Galli,C., Ciotti,T. and Calissano,P. (1993) Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP. Proc. Natl Acad. Sci. USA, 90, 10989-10993.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 10989-10993
    • D'Mello, S.R.1    Galli, C.2    Ciotti, T.3    Calissano, P.4
  • 26
    • 0022996750 scopus 로고
    • IL-2 addictions: Withdrawal of growth factor activates a suicide program in dependent T cells
    • Duke,R.C. and Cohen,J.J. (1986) IL-2 addictions: withdrawal of growth factor activates a suicide program in dependent T cells. Lymphokine Res., 5, 289-299.
    • (1986) Lymphokine Res. , vol.5 , pp. 289-299
    • Duke, R.C.1    Cohen, J.J.2
  • 27
    • 0024396222 scopus 로고
    • Chimeras of Myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells
    • Eilers,M., Picard,D., Yamamoto,K.R. and Bishop,J.M. (1989) Chimeras of Myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells. Nature, 340, 66-68.
    • (1989) Nature , vol.340 , pp. 66-68
    • Eilers, M.1    Picard, D.2    Yamamoto, K.R.3    Bishop, J.M.4
  • 28
    • 0026099022 scopus 로고
    • The MYC protein activates transcription of a-prothymosin gene
    • Eilers,M., Schirm,S. and Bishop,J.M. (1991) The MYC protein activates transcription of a-prothymosin gene. EMBO J., 10, 133-141.
    • (1991) EMBO J. , vol.10 , pp. 133-141
    • Eilers, M.1    Schirm, S.2    Bishop, J.M.3
  • 29
    • 0027359827 scopus 로고
    • WAF-1, a potential mediator of p53 tumor suppression
    • El-Deiry,W.S. et al. (1993) WAF-1, a potential mediator of p53 tumor suppression. Cell, 75, 817-825.
    • (1993) Cell , vol.75 , pp. 817-825
    • El-Deiry, W.S.1
  • 31
    • 0027946686 scopus 로고
    • Altered gene expression in neurons during programmed cell death: Identification of c-jun as necessary for neuronal apoptosis
    • Estus,S., Zaks,W.J., Freeman,R.S., Gruda,M., Bravo,R. and Johnson,E.M.,Jr (1994) Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis. J. Cell Biol., 127, 1717-1727.
    • (1994) J. Cell Biol. , vol.127 , pp. 1717-1727
    • Estus, S.1    Zaks, W.J.2    Freeman, R.S.3    Gruda, M.4    Bravo, R.5    Johnson Jr., E.M.6
  • 33
    • 0023159034 scopus 로고
    • Induction and activation of tissue transglutaminase during programmed cell death
    • Fesus,L., Thomazy,V. and Falus,A. (1987) Induction and activation of tissue transglutaminase during programmed cell death. FEBS Lett., 224, 104-108.
    • (1987) FEBS Lett. , vol.224 , pp. 104-108
    • Fesus, L.1    Thomazy, V.2    Falus, A.3
  • 36
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Gavrieli,J., Sherman,Y. and Ben-Sasson,S.A. (1992) Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol., 119, 493-501.
    • (1992) J. Cell Biol. , vol.119 , pp. 493-501
    • Gavrieli, J.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 37
    • 0028109974 scopus 로고
    • Differential regulation of c-fos, fosB, c-jun, junB, bcl-2 and bax expression in rat skin following single or chronic ultraviolet radiation and in vivo modulation by antisense oligonucleotide superfusion
    • Gillardon,F., Eschenfelder,C., Uhlmann,E., Hartschuh,W. and Zimmermann,M. (1994) Differential regulation of c-fos, fosB, c-jun, junB, bcl-2 and bax expression in rat skin following single or chronic ultraviolet radiation and in vivo modulation by antisense oligonucleotide superfusion. Oncogene, 9, 3219-3225.
    • (1994) Oncogene , vol.9 , pp. 3219-3225
    • Gillardon, F.1    Eschenfelder, C.2    Uhlmann, E.3    Hartschuh, W.4    Zimmermann, M.5
  • 38
    • 0028245685 scopus 로고
    • Prolonged expression of c-jun and associated activity of transcription factor AP-1, during apoptosis in human leukaemic cell line
    • Goldstone,S.D. and Lavin,M.F. (1994) Prolonged expression of c-jun and associated activity of transcription factor AP-1, during apoptosis in human leukaemic cell line. Oncogene, 9, 2305-2311.
    • (1994) Oncogene , vol.9 , pp. 2305-2311
    • Goldstone, S.D.1    Lavin, M.F.2
  • 39
    • 0026483348 scopus 로고
    • Studies of the relationship between cell proliferation and cell death. II. Early gene expression during concanavalin A-induced proliferation or dexamethasone-induced apoptosis of rat thymocytes
    • Grasselli,E., de Prati,A.C., Monti,D., Troiano,L., Menegazzi,M., Barbieri,D., Franceschi,C. and Suzuki,H. (1992) Studies of the relationship between cell proliferation and cell death. II. Early gene expression during concanavalin A-induced proliferation or dexamethasone-induced apoptosis of rat thymocytes. Biochem. Biophys. Res. Commun., 188, 1261-1266.
    • (1992) Biochem. Biophys. Res. Commun. , vol.188 , pp. 1261-1266
    • Grasselli, E.1    De Prati, A.C.2    Monti, D.3    Troiano, L.4    Menegazzi, M.5    Barbieri, D.6    Franceschi, C.7    Suzuki, H.8
  • 40
    • 0025878233 scopus 로고
    • Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity
    • Hai,T. and Curran,T. (1991) Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity. Proc. Natl Acad. Sci. USA, 88, 3720-3724.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 3720-3724
    • Hai, T.1    Curran, T.2
  • 43
    • 0029012476 scopus 로고
    • A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death
    • Ham,J., Babij,C., Whitefield,J., Pfarr,C.M., Lallemand,D., Yaniv,M. and Rubin,L.L. (1995) A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death. Neuron, 14, 927-939.
    • (1995) Neuron , vol.14 , pp. 927-939
    • Ham, J.1    Babij, C.2    Whitefield, J.3    Pfarr, C.M.4    Lallemand, D.5    Yaniv, M.6    Rubin, L.L.7
  • 44
    • 0027496935 scopus 로고
    • The p21 cdk-interacting protein Cip-1 is a potent inhibitor of G1 cyclin-dependent kinases
    • Harper,J.W., Adami,G.R., Wei,N., Keyomarsi,K. and Elledge,S.J. (1993) The p21 cdk-interacting protein Cip-1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell, 75, 805-816.
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 45
    • 0026453516 scopus 로고
    • Embryonic stem (ES) cells lacking functional c-jun: Consequences for growth and differentation, AP-1 activity and tumorigenicity
    • Hilberg,F. and Wagner,E.F. (1992) Embryonic stem (ES) cells lacking functional c-jun: consequences for growth and differentation, AP-1 activity and tumorigenicity. Oncogene, 7, 2371-2380.
    • (1992) Oncogene , vol.7 , pp. 2371-2380
    • Hilberg, F.1    Wagner, E.F.2
  • 46
    • 0027242180 scopus 로고
    • C-Jun is essential for normal mouse development and hepatogenesis
    • Hilberg,F., Aguzzi,A., Howells,N. and Wagner,E.F. (1993) c-Jun is essential for normal mouse development and hepatogenesis. Nature, 365, 179-181.
    • (1993) Nature , vol.365 , pp. 179-181
    • Hilberg, F.1    Aguzzi, A.2    Howells, N.3    Wagner, E.F.4
  • 47
    • 0024407432 scopus 로고
    • Characterization of junD: A new member of the jun proto-oncogene family
    • Hirai,S.-I., Ryseck,R.-P. Mechta,F., Bravo,R. and Yaniv,M. (1989) Characterization of junD: a new member of the jun proto-oncogene family. EMBO J., 8, 1433-1439.
    • (1989) EMBO J. , vol.8 , pp. 1433-1439
    • Hirai, S.-I.1    Ryseck, R.-P.2    Mechta, F.3    Bravo, R.4    Yaniv, M.5
  • 48
    • 0027219303 scopus 로고
    • A null mutation at the c-jun locus causes embryonic lethality and retarded cell growth in culture
    • Johnson,R.S., van Lingen,B., Papaioannou,V.E. and Spiegelman,B.M. (1993) A null mutation at the c-jun locus causes embryonic lethality and retarded cell growth in culture. Genes Dev., 7, 1309-1317.
    • (1993) Genes Dev. , vol.7 , pp. 1309-1317
    • Johnson, R.S.1    Van Lingen, B.2    Papaioannou, V.E.3    Spiegelman, B.M.4
  • 49
    • 0028322193 scopus 로고
    • Signal transduction from the cell surface to the nucleus through the phosphorylation of the transcription factors
    • Karin,M. (1994) Signal transduction from the cell surface to the nucleus through the phosphorylation of the transcription factors. Curr. Opin. Cell Biol., 6, 415-424.
    • (1994) Curr. Opin. Cell Biol. , vol.6 , pp. 415-424
    • Karin, M.1
  • 50
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide ranging implications in tissue kinetics
    • Kerr,J.F.R., Wyllie,A.H. and Currie,A.R. (1972) Apoptosis: a basic biological phenomenon with wide ranging implications in tissue kinetics. Br. J. Cancer, 26, 239-257.
    • (1972) Br. J. Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.R.1    Wyllie, A.H.2    Currie, A.R.3
  • 51
    • 0029972806 scopus 로고    scopus 로고
    • p53: Puzzle and paradigm
    • Ko,L.J. and Prives,C. (1996) p53: puzzle and paradigm. Genes Dev., 10, 1054-1072.
    • (1996) Genes Dev. , vol.10 , pp. 1054-1072
    • Ko, L.J.1    Prives, C.2
  • 52
    • 0026695699 scopus 로고
    • Bcl-2: A repressor of lymphocyte death
    • Korsmeyer,S.J. (1992) Bcl-2: a repressor of lymphocyte death. Immunol. Today, 13, 285-288.
    • (1992) Immunol. Today , vol.13 , pp. 285-288
    • Korsmeyer, S.J.1
  • 53
    • 0025882879 scopus 로고
    • The Jun and Fos protein family are both required for cell cycle progression in fibroblasts
    • Kovary,K. and Bravo,R. (1991) The Jun and Fos protein family are both required for cell cycle progression in fibroblasts. Mol. Cell Biol., 11, 4466-4472.
    • (1991) Mol. Cell Biol. , vol.11 , pp. 4466-4472
    • Kovary, K.1    Bravo, R.2
  • 54
    • 0029814061 scopus 로고    scopus 로고
    • Anti apoptotic activity of low levels of wild-type p53
    • Lassus,P., Ferlin,M. Piette,J. and Hibner,U. (1996) Anti apoptotic activity of low levels of wild-type p53. EMBO J., 15, 4566-4573.
    • (1996) EMBO J. , vol.15 , pp. 4566-4573
    • Lassus, P.1    Ferlin, M.2    Piette, J.3    Hibner, U.4
  • 55
    • 0023611441 scopus 로고
    • Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements
    • Lee,W., Mitchell,P. and Tjian,R. (1987) Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements. Cell, 49, 741-752.
    • (1987) Cell , vol.49 , pp. 741-752
    • Lee, W.1    Mitchell, P.2    Tjian, R.3
  • 56
    • 0027976193 scopus 로고
    • Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nurr 77
    • Liu,Z.-G., Smith,S.W., McLaughlin,K.A., Schwartz,L.M. and Osborne, B.A. (1994) Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nurr 77. Nature, 367, 281-284.
    • (1994) Nature , vol.367 , pp. 281-284
    • Liu, Z.-G.1    Smith, S.W.2    McLaughlin, K.A.3    Schwartz, L.M.4    Osborne, B.A.5
  • 57
    • 0027319521 scopus 로고
    • p53 is required for radiation induced apoptosis in mouse thymocytes
    • Lowe,S.W., Schmitt,E.M., Smith,S.W., Osborne,B.A. and Jacks,T. (1993) p53 is required for radiation induced apoptosis in mouse thymocytes. Nature, 362, 847-849.
    • (1993) Nature , vol.362 , pp. 847-849
    • Lowe, S.W.1    Schmitt, E.M.2    Smith, S.W.3    Osborne, B.A.4    Jacks, T.5
  • 59
    • 0027518136 scopus 로고
    • Coinduction of c-jun gene expression and intemucleosomal DNA fragmentation by ionizing radiation
    • Manome,Y., Datta,R., Taneja,N., Shafman,T., Bump,E., Hass,R., Weichselbaum,R. and Kufe,D. (1993) Coinduction of c-jun gene expression and intemucleosomal DNA fragmentation by ionizing radiation. Biochemistry, 32, 10607-10613.
    • (1993) Biochemistry , vol.32 , pp. 10607-10613
    • Manome, Y.1    Datta, R.2    Taneja, N.3    Shafman, T.4    Bump, E.5    Hass, R.6    Weichselbaum, R.7    Kufe, D.8
  • 60
    • 0028215344 scopus 로고
    • Protein kinase a and AP-1 (c-Fos/JunD) are induced during apoptosis of mouse mammary epithelial cells
    • Marti,A., Jehn,B., Costello,E., Keon,N., Ke,G., Martin,F. and Jaggi,R. (1994) Protein kinase A and AP-1 (c-Fos/JunD) are induced during apoptosis of mouse mammary epithelial cells. Oncogene, 9, 1213-1223.
    • (1994) Oncogene , vol.9 , pp. 1213-1223
    • Marti, A.1    Jehn, B.2    Costello, E.3    Keon, N.4    Ke, G.5    Martin, F.6    Jaggi, R.7
  • 61
    • 0023851503 scopus 로고
    • Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation
    • Martin,D.P., Schmidt,R.E., DiStefano,P.S., Lowry,O.H., Carter,J.G. and Johnson,E.M.,Jr (1988) Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation. J. Cell Biol., 106, 829-844.
    • (1988) J. Cell Biol. , vol.106 , pp. 829-844
    • Martin, D.P.1    Schmidt, R.E.2    DiStefano, P.S.3    Lowry, O.H.4    Carter, J.G.5    Johnson Jr., E.M.6
  • 62
    • 0027411586 scopus 로고
    • Apoptosis: Suicide, execution or murder?
    • Martin,S.J. (1993) Apoptosis: suicide, execution or murder? Trends Cell Biol., 3, 141-144.
    • (1993) Trends Cell Biol. , vol.3 , pp. 141-144
    • Martin, S.J.1
  • 63
    • 0029125701 scopus 로고
    • Protease activation during apoptosis: Death by thousand cuts?
    • Martin,S.J. and Green,D.R. (1995) Protease activation during apoptosis: death by thousand cuts? Cell, 82, 349-352.
    • (1995) Cell , vol.82 , pp. 349-352
    • Martin, S.J.1    Green, D.R.2
  • 65
    • 0028047723 scopus 로고
    • The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice
    • Merritt,A.J., Potten,C.S., Kemp,C.J., Hickman,J.A., Balmain,A., Lane,D.P. and Hall,P.A. (1994) The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice. Cancer Res., 54, 614-617.
    • (1994) Cancer Res. , vol.54 , pp. 614-617
    • Merritt, A.J.1    Potten, C.S.2    Kemp, C.J.3    Hickman, J.A.4    Balmain, A.5    Lane, D.P.6    Hall, P.A.7
  • 66
    • 0028286296 scopus 로고
    • Motoneurons deprived of trophic support in vitro require new gene expression to undergo programmed cell death
    • Milligan,C.E., Oppenheim,R.W. and Schwartz,L.M. (1994) Motoneurons deprived of trophic support in vitro require new gene expression to undergo programmed cell death. J. Neurobiol., 25, 1005-1016.
    • (1994) J. Neurobiol. , vol.25 , pp. 1005-1016
    • Milligan, C.E.1    Oppenheim, R.W.2    Schwartz, L.M.3
  • 67
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • Miyashita,T. and Reed,J.C. (1995) Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell, 80, 293-299.
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 68
    • 0029619087 scopus 로고
    • NF-M (chicken C/EBPb) induces eosinophilic differentiation and apoptosis in a hematopoietic progenitor cell line
    • Müller,C., Kowenz-Leutz,E., Grieser-Ade,S., Graf,T. and Leutz,A. (1995) NF-M (chicken C/EBPb) induces eosinophilic differentiation and apoptosis in a hematopoietic progenitor cell line. EMBO J., 14, 6127-6135.
    • (1995) EMBO J. , vol.14 , pp. 6127-6135
    • Müller, C.1    Kowenz-Leutz, E.2    Grieser-Ade, S.3    Graf, T.4    Leutz, A.5
  • 69
    • 0029068871 scopus 로고
    • Identification and inhibition of the ICE/ CED-3 protease necessary for mammalian apoptosis
    • Nicholson,D.W. et al. (1995) Identification and inhibition of the ICE/ CED-3 protease necessary for mammalian apoptosis. Nature, 376, 37-43.
    • (1995) Nature , vol.376 , pp. 37-43
    • Nicholson, D.W.1
  • 70
    • 0025255538 scopus 로고
    • Deregulated bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines
    • Nunez,G., London,L., Hockenbery,D., Alexander,M., McKearn,J.P. and Korsmeyer,S.J. (1990) Deregulated bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines. J. Immunol., 144, 3602-3610.
    • (1990) J. Immunol. , vol.144 , pp. 3602-3610
    • Nunez, G.1    London, L.2    Hockenbery, D.3    Alexander, M.4    McKearn, J.P.5    Korsmeyer, S.J.6
  • 71
    • 0025217864 scopus 로고
    • Naturally occurring and induced neuronal death in the chick embryo in vivo requires protein and RNA synthesis: Evidence for the role of cell death genes
    • Oppenheim,R.W., Prevette,D., Tytell,M. and Homma,S. (1990) Naturally occurring and induced neuronal death in the chick embryo in vivo requires protein and RNA synthesis: evidence for the role of cell death genes. Dev. Biol., 138, 104-103.
    • (1990) Dev. Biol. , vol.138 , pp. 104-1103
    • Oppenheim, R.W.1    Prevette, D.2    Tytell, M.3    Homma, S.4
  • 72
    • 0028325891 scopus 로고
    • Mouse JunD negatively regulates fibroblast growth and antagonizes transformation by ras
    • Pfarr,C.M., Mechta,F., Spyrou,G., Lallemand,D., Carillo,S. and Yaniv,M. (1994) Mouse JunD negatively regulates fibroblast growth and antagonizes transformation by ras. Cell, 76, 747-760.
    • (1994) Cell , vol.76 , pp. 747-760
    • Pfarr, C.M.1    Mechta, F.2    Spyrou, G.3    Lallemand, D.4    Carillo, S.5    Yaniv, M.6
  • 73
    • 0026018673 scopus 로고
    • Tissue transglutaminase is specifically expressed in neonatal rat liver undergoing apoptosis upon epidermal growth factor stimulation
    • Piacentini,M., Autuori,F., Dini,L., Farrace,M.G., Ghibelli,L., Piredda,L. and Fesus,L. (1991) Tissue transglutaminase is specifically expressed in neonatal rat liver undergoing apoptosis upon epidermal growth factor stimulation. Cell Tissue Res., 263, 227-235.
    • (1991) Cell Tissue Res. , vol.263 , pp. 227-235
    • Piacentini, M.1    Autuori, F.2    Dini, L.3    Farrace, M.G.4    Ghibelli, L.5    Piredda, L.6    Fesus, L.7
  • 74
    • 0028114235 scopus 로고
    • Regulation of protein function through expression of chimaeric proteins
    • Picard,D. (1994) Regulation of protein function through expression of chimaeric proteins. Curr. Biol., 5, 511-515.
    • (1994) Curr. Biol. , vol.5 , pp. 511-515
    • Picard, D.1
  • 76
    • 0027947383 scopus 로고
    • Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
    • Qin,X.-Q., Livingston,D.M., Kaelin,W.G. and Adams,P.D. (1994) Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc. Natl Acad. Sci. USA, 91, 10918-10922.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 10918-10922
    • Qin, X.-Q.1    Livingston, D.M.2    Kaelin, W.G.3    Adams, P.D.4
  • 77
    • 0026504147 scopus 로고
    • Social controls on cell survival and cell death
    • Raff,M.C. (1992) Social controls on cell survival and cell death. Nature, 356, 397-400.
    • (1992) Nature , vol.356 , pp. 397-400
    • Raff, M.C.1
  • 78
    • 0027373764 scopus 로고
    • Programmed cell death and the control of cell survival: Lessons from the nervous system
    • Raff,M.C., Barres,B.A., Burne,J.F., Coles,H.S., Ishizaki,Y. and Jacobson,M.D. (1993) Programmed cell death and the control of cell survival: lessons from the nervous system. Science, 262, 695-700.
    • (1993) Science , vol.262 , pp. 695-700
    • Raff, M.C.1    Barres, B.A.2    Burne, J.F.3    Coles, H.S.4    Ishizaki, Y.5    Jacobson, M.D.6
  • 79
    • 0028040019 scopus 로고
    • Bcl-2 and the regulation of programmed cell death
    • Reed,J.C. (1995) Bcl-2 and the regulation of programmed cell death. J. Cell Biol., 124, 1-6.
    • (1995) J. Cell Biol. , vol.124 , pp. 1-6
    • Reed, J.C.1
  • 80
    • 0024026804 scopus 로고
    • Ras-mediated cell-cycle arrest is altered by nuclear oncogenes to induce Schwann cell transformation
    • Ridley,A.J., Paterson,H.F., Noble,M. and Land,H. (1988) Ras-mediated cell-cycle arrest is altered by nuclear oncogenes to induce Schwann cell transformation. EMBO J., 7, 1635-1645.
    • (1988) EMBO J. , vol.7 , pp. 1635-1645
    • Ridley, A.J.1    Paterson, H.F.2    Noble, M.3    Land, H.4
  • 83
    • 0025829599 scopus 로고
    • C-Jun, JunB and JunD differ in their binding affinities to AP-1 and CRE consensus sequences: Effect of Fos proteins
    • Ryseck,R.-P. and Bravo,R. (1991) c-Jun, JunB and JunD differ in their binding affinities to AP-1 and CRE consensus sequences: effect of Fos proteins. Oncogene, 6, 533-542.
    • (1991) Oncogene , vol.6 , pp. 533-542
    • Ryseck, R.-P.1    Bravo, R.2
  • 84
    • 0023694843 scopus 로고
    • Transcriptional activation of c-jun during the G0/G1 transition in mouse fibroblasts
    • Ryseck,R.-P., Hirai,S.I., Yaniv,M. and Bravo,R. (1988) Transcriptional activation of c-jun during the G0/G1 transition in mouse fibroblasts. Nature, 334, 535-537.
    • (1988) Nature , vol.334 , pp. 535-537
    • Ryseck, R.-P.1    Hirai, S.I.2    Yaniv, M.3    Bravo, R.4
  • 86
    • 0010638187 scopus 로고
    • Deregulated expression of human c-jun transforms primary rat embryo cells in cooperation with an activated c-Ha-ras gene and transforms rat-la cells as a single gene
    • Scḧtte,J. Minna,J.D. and Birrer,M. (1989a) Deregulated expression of human c-jun transforms primary rat embryo cells in cooperation with an activated c-Ha-ras gene and transforms rat-la cells as a single gene. Proc. Natl Acad. Sci. USA, 86, 2257-2261.
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 2257-2261
    • Scḧtte, J.1    Minna, J.D.2    Birrer, M.3
  • 87
    • 0024800229 scopus 로고
    • JunB inhibits and c-fos stimulates the transforming and trans-activation activities of c-jun
    • Schütte,J., Viallet,J., Nau,M., Segal,S., Fedorko,J. and Minna,J. (1989b) junB inhibits and c-fos stimulates the transforming and trans-activation activities of c-jun. Cell, 59, 987-997.
    • (1989) Cell , vol.59 , pp. 987-997
    • Schütte, J.1    Viallet, J.2    Nau, M.3    Segal, S.4    Fedorko, J.5    Minna, J.6
  • 88
    • 0027333347 scopus 로고
    • Programmed cell death, apoptosis and killer genes
    • Schwartz,L.M. and Osborne,B.A. (1993) Programmed cell death, apoptosis and killer genes, Immunol. Today, 14, 582-590.
    • (1993) Immunol. Today , vol.14 , pp. 582-590
    • Schwartz, L.M.1    Osborne, B.A.2
  • 89
    • 0025354667 scopus 로고
    • Inhibition of protein synthesis prevents cell death in sensory and parasympathetic neurons deprived of neurotrophic factor in vitro
    • Scott,S.A. and Davies,A.M. (1990) Inhibition of protein synthesis prevents cell death in sensory and parasympathetic neurons deprived of neurotrophic factor in vitro. J. Neurobiol., 21, 630-638.
    • (1990) J. Neurobiol. , vol.21 , pp. 630-638
    • Scott, S.A.1    Davies, A.M.2
  • 90
    • 0023612470 scopus 로고
    • Gene induction by g-irradiation leads to DNA fragmentation in lymphocytes
    • Sellins,K.S. and Cohen,J.J. (1987) Gene induction by g-irradiation leads to DNA fragmentation in lymphocytes. J. Immunol., 139, 3199-3206.
    • (1987) J. Immunol. , vol.139 , pp. 3199-3206
    • Sellins, K.S.1    Cohen, J.J.2
  • 91
    • 0025751550 scopus 로고
    • Bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes
    • Sentman,C.L., Shutter,J.R., Hockenbery,D., Kanagawa,O. and Korsmeyer,S.J. (1991) bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes. Cell, 67, 879-888.
    • (1991) Cell , vol.67 , pp. 879-888
    • Sentman, C.L.1    Shutter, J.R.2    Hockenbery, D.3    Kanagawa, O.4    Korsmeyer, S.J.5
  • 92
    • 0028061670 scopus 로고
    • Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis
    • Shan,B. and Lee,W.-H. (1994) Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis. Mol. Cell Biol., 14, 8166-8173.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 8166-8173
    • Shan, B.1    Lee, W.-H.2
  • 93
    • 0025232724 scopus 로고
    • Activation-induced cell death in T cell hybridomas is due to apoptosis
    • Shi,J., Szalay,M.G., Paskar,L., Boyer,M., Shingh,B. and Green,D.R. (1990) Activation-induced cell death in T cell hybridomas is due to apoptosis. J. Immunol., 144, 3326-3333.
    • (1990) J. Immunol. , vol.144 , pp. 3326-3333
    • Shi, J.1    Szalay, M.G.2    Paskar, L.3    Boyer, M.4    Shingh, B.5    Green, D.R.6
  • 94
  • 95
    • 0027724772 scopus 로고
    • Transcription factors DNA-binding activity in rat thymocytes undergoing apoptosis after heat-shock or dexamethasone treatment
    • Sikora,E., Grasselli,E., Radziszeweska,E., Bellesia,E., Barbieri,D. and Franceschi,C. (1993) Transcription factors DNA-binding activity in rat thymocytes undergoing apoptosis after heat-shock or dexamethasone treatment. Biochem. Biophys. Res. Commun., 197, 709-715.
    • (1993) Biochem. Biophys. Res. Commun. , vol.197 , pp. 709-715
    • Sikora, E.1    Grasselli, E.2    Radziszeweska, E.3    Bellesia, E.4    Barbieri, D.5    Franceschi, C.6
  • 96
    • 0025788098 scopus 로고
    • Oncogenic and transcriptional cooperation with Ha-ras requires phosphorylation of c-Jun on serine 63 and 73
    • Smeal,T., Binetruy,B., Mercola,D.A., Birrer,M. and Karin,M. (1991) Oncogenic and transcriptional cooperation with Ha-ras requires phosphorylation of c-Jun on serine 63 and 73. Nature, 354, 494-496.
    • (1991) Nature , vol.354 , pp. 494-496
    • Smeal, T.1    Binetruy, B.2    Mercola, D.A.3    Birrer, M.4    Karin, M.5
  • 98
    • 0028929328 scopus 로고
    • Mechanisms and genes of cellular suicide
    • Steller,H. (1995) Mechanisms and genes of cellular suicide. Science, 267, 1445-1449.
    • (1995) Science , vol.267 , pp. 1445-1449
    • Steller, H.1
  • 99
    • 0029609086 scopus 로고
    • Bcl-2 and Fas/Apo-1 regulates distinct pathways to lymphocyte apoptosis
    • Strasser,A., Harris,A.W., Huang,D.C.S., Krammer,P.H. and Cory,S. (1995) Bcl-2 and Fas/Apo-1 regulates distinct pathways to lymphocyte apoptosis. EMBO J., 14, 6136-45147.
    • (1995) EMBO J. , vol.14 , pp. 6136-45147
    • Strasser, A.1    Harris, A.W.2    Huang, D.C.S.3    Krammer, P.H.4    Cory, S.5
  • 100
    • 0028990125 scopus 로고
    • Yama/ CPP32 β, a mammalian homolog of CED-3, is a crmA-inhibitable protease that cleaves the death substrate poly (ADP-ribose) polymerase
    • Tewari,M., Quan,L.T., O'Rourke,S., Desnoyers,Z., Zeng,D.R., Beidler,G.G., Poirier,G.S., Salvesen,G.S. and Dixit,V.M. (1995) Yama/ CPP32 β, a mammalian homolog of CED-3, is a crmA-inhibitable protease that cleaves the death substrate poly (ADP-ribose) polymerase. Cell, 81, 801-809.
    • (1995) Cell , vol.81 , pp. 801-809
    • Tewari, M.1    Quan, L.T.2    O'Rourke, S.3    Desnoyers, Z.4    Zeng, D.R.5    Beidler, G.G.6    Poirier, G.S.7    Salvesen, G.S.8    Dixit, V.M.9
  • 101
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson,C.B. (1995) Apoptosis in the pathogenesis and treatment of disease. Science, 267, 1456-1462.
    • (1995) Science , vol.267 , pp. 1456-1462
    • Thompson, C.B.1
  • 102
    • 0026507126 scopus 로고
    • A novel heterodimeric cysteine protease is required for interleukin-1β processing in monocytes
    • Thornberry,N.A. et al. (1992) A novel heterodimeric cysteine protease is required for interleukin-1β processing in monocytes. Nature, 356, 768-774.
    • (1992) Nature , vol.356 , pp. 768-774
    • Thornberry, N.A.1
  • 103
    • 0005373489 scopus 로고
    • Interleukin-1β converting enzyme and related proteases as potential targets in inflammation and apoptosis
    • Thornberry,N.D., Miller,S.M. and Nicholson,D. (1995) Interleukin-1β converting enzyme and related proteases as potential targets in inflammation and apoptosis. Perspect. Drug Discovery Design, 2, 389-399.
    • (1995) Perspect. Drug Discovery Design , vol.2 , pp. 389-399
    • Thornberry, N.D.1    Miller, S.M.2    Nicholson, D.3
  • 104
    • 0028027308 scopus 로고
    • Ubiquitin-dependent c-Jun degradation in vivo is mediated by the d domain
    • Treier,M., Staszewski,L.M. and Bohmann,D. (1994) Ubiquitin-dependent c-Jun degradation in vivo is mediated by the d domain. Cell, 78, 787-798.
    • (1994) Cell , vol.78 , pp. 787-798
    • Treier, M.1    Staszewski, L.M.2    Bohmann, D.3
  • 106
    • 0026651522 scopus 로고
    • Bcl-2 prevents death of factor-deprived cells but fails to prevent apoptosis in target of cell mediated killing
    • Vaux,D.L., Aguila,H.L. and Weissman,I.L. (1992) Bcl-2 prevents death of factor-deprived cells but fails to prevent apoptosis in target of cell mediated killing. Int. Immunol., 4, 821-824.
    • (1992) Int. Immunol. , vol.4 , pp. 821-824
    • Vaux, D.L.1    Aguila, H.L.2    Weissman, I.L.3
  • 107
    • 0347537940 scopus 로고    scopus 로고
    • Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis
    • Verheij,M. et al. (1996) Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis. Nature, 380, 75-79.
    • (1996) Nature , vol.380 , pp. 75-79
    • Verheij, M.1
  • 108
    • 0025126386 scopus 로고
    • Jun: Oncogene and transcription factor
    • Vogt,P. and Bos,T.J, (1990) Jun: oncogene and transcription factor. Adv. Cancer Res., 55, 1-35.
    • (1990) Adv. Cancer Res. , vol.55 , pp. 1-35
    • Vogt, P.1    Bos, T.J.2
  • 109
    • 0029894529 scopus 로고    scopus 로고
    • ICE/CED-3 proteases in apoptosis
    • Whyte,M. (1996) ICE/CED-3 proteases in apoptosis. Trends Cell Biol., 6, 245-248.
    • (1996) Trends Cell Biol. , vol.6 , pp. 245-248
    • Whyte, M.1
  • 110
    • 0028008513 scopus 로고
    • Requirement for the orphan steroid receptor Nurr 77 in apoptosis of T cell hybridomas
    • Woronicz,J.D., Calnan,B., Ngo,V. and Winoto,A. (1994) Requirement for the orphan steroid receptor Nurr 77 in apoptosis of T cell hybridomas. Nature, 367, 277-281.
    • (1994) Nature , vol.367 , pp. 277-281
    • Woronicz, J.D.1    Calnan, B.2    Ngo, V.3    Winoto, A.4
  • 111
    • 0028222124 scopus 로고
    • p53 and E2F-1 cooperate to mediate apoptosis
    • Wu,X. and Levine,A.J. (1994) p53 and E2F-1 cooperate to mediate apoptosis. Proc. Natl Acad. Sci. USA, 91, 3602-3606.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 3602-3606
    • Wu, X.1    Levine, A.J.2
  • 112
    • 0019225636 scopus 로고
    • Cell death: The significance of apoptosis
    • Wyllie,A.H., Kerr,J.R. and Currie,A.R. (1980) Cell death: the significance of apoptosis. Int. Rev. Cytol., 68, 251-306.
    • (1980) Int. Rev. Cytol. , vol.68 , pp. 251-306
    • Wyllie, A.H.1    Kerr, J.R.2    Currie, A.R.3
  • 113
    • 0023635251 scopus 로고
    • Rodent fibroblast tumours expressing human myc and ras genes: Growth, metastasis and endogenous oncogene expression
    • Wyllie,A.H., Rose,K.A., Morris,R.G., Steel,C.M., Foster,E. and Spandidas,D.A. (1987) Rodent fibroblast tumours expressing human myc and ras genes: growth, metastasis and endogenous oncogene expression. Br. J. Cancer, 56, 251-259.
    • (1987) Br. J. Cancer , vol.56 , pp. 251-259
    • Wyllie, A.H.1    Rose, K.A.2    Morris, R.G.3    Steel, C.M.4    Foster, E.5    Spandidas, D.A.6
  • 114
    • 0028880006 scopus 로고
    • Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
    • Xia,Z., Dichens,M., Raingeaud,J., Davis,R.J. and Greenberg,M.E. (1995) Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science, 270, 1326-1331.
    • (1995) Science , vol.270 , pp. 1326-1331
    • Xia, Z.1    Dichens, M.2    Raingeaud, J.3    Davis, R.J.4    Greenberg, M.E.5
  • 115
    • 0029056059 scopus 로고
    • Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus 35 protein
    • Xue,D. and Horvitz,H.R. (1995) Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus 35 protein. Nature, 377, 248-251.
    • (1995) Nature , vol.377 , pp. 248-251
    • Xue, D.1    Horvitz, H.R.2
  • 117
    • 0025784539 scopus 로고
    • Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
    • Yonish-Rouach,E., Resnitzky,D., Lotem,J., Sachs,L., Kimchi,A. and Oren,M. (1991) Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature, 352, 345-347.
    • (1991) Nature , vol.352 , pp. 345-347
    • Yonish-Rouach, E.1    Resnitzky, D.2    Lotem, J.3    Sachs, L.4    Kimchi, A.5    Oren, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.