Correlation between hyperproliferation and suprabasal integrin expression in human epidermis reconstituted in culture

Experimental Dermatology

Volumn 6, Issue 5, 1997, Pages 214-221

  Rikimaru, K ^a,b   Moles J P ^a,c   Watt, F M ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

^c UNIV MONTPELLIER   (France)

Author keywords

Differentiation; EGF receptor; Integrins; Keratinocytes; Proliferation

Indexed keywords

ARTICLE; CELL PROLIFERATION; EPIDERMIS; GENE EXPRESSION; HUMAN; HUMAN CELL; INFLAMMATION; KERATINOCYTE; PATHOGENESIS; PHENOTYPE; WOUND HEALING;

ANTIBODIES, MONOCLONAL; CELL DIFFERENTIATION; CELL DIVISION; CELLS, CULTURED; HUMANS; IMMUNOENZYME TECHNIQUES; INTEGRINS; KERATINOCYTES; KERATINS; KI-67 ANTIGEN; RECEPTOR, EPIDERMAL GROWTH FACTOR; SKIN;

EID: 0030813551     PISSN: 09066705     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0625.1997.tb00165.x     Document Type: Article

References (13)

1. Watt F M, Hertle M D. Keratinocyte integrins. In: Leigh I M, Lane E B, Watt, F M, eds. The keratinocyte handbook. Cambridge: Cambridge University Press, 1994: 153-164.
2. Borradori L, Sonnenberg A. Hemidesmosomes: roles in adhesion, signaling and human diseases. Curr Opin Cell Biol 1996: 8: 647-656.
3. Watt F M, Jones P H. Expression and function of the keratinocyte integrins. Dev Suppl 1993: 185-192.
4. Jones P H, Harper S, Watt F M. Stem cell patterning and fate in human epidermis. Cell 1995: 80: 83-93.
5. Hertle M D, Kubler M-D, Leigh I M, Watt F M. Aberrant integrin expression during epidermal wound healing and in psoriatic epidermis. J Clin Invest 1992: 89: 1892-1901.
6. Cavani A, Zambruno G, Marconi A, Manca V, Marchetti M, Giannetti A. Distinctive integrin expression in the newly forming epidermis during wound healing in humans. J Invest Dermatol 1993: 101: 600-604.
7. Juhasz I, Murphy G F, Yan H-C, Herlyn M, Albelda S M. Regulation of extracellular matrix proteins and integrin cell substratum adhesion receptors on epithelium during cutaneous human wound healing in vivo. Am J Pathol 1993: 143: 1458-1469.
8. Kellner I, Konter U, Sterry W. Overexpression of extracellular matrix receptors (VLA-3, 5 and 6) on psoriatic keratinocytes. Br J Dermatol 1991: 125: 211-216.
9. Ralfkiaer E, Thomsen K, Vejlsgaard G L. Expression of a cell adhesion protein (VLAβ) in normal and diseased skin. Br J Dermatol 1991: 124: 527-532.
10. Von den Driesch P, Fartasch M, Hüner A, Ponec M. Expression of integrin receptors and ICAM-1 on keratinocytes in vivo and in an in vitro reconstructed epidermis: effect of sodium dodecyl sulphate. Arch Dermatol Res 1995: 287: 249-253.
11. Carroll J M, Romero M R, Watt F M. Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis. Cell 1995: 83: 957-968.
12. Hertle M D, Jones P H, Groves R W, Hudson D L, Watt F M. Integrin expression by human epidermal keratinocytes can be modulated by interferon-γ, transforming growth factor-β, tumor necrosis factor-α and culture on a dermal equivalent. J Invest Dermatol 1995: 104: 260-265.
13. Watt F M. Cultivation of human epidermal keratinocytes with a 3T3 feeder layer. In: Celis J E, ed. Cell biology: A laboratory handbook. San Diego: Academic Press, 1994: Vol. 1: 83-89.