-
1
-
-
0029066265
-
Effects of the obese gene product on body weight regulation in ob/ob mice
-
Pelleymounter, M. A., Cullen, M. J., Baker, M. B., Hecht, R., Winters, D., Boone, T., and Collins, F. (1995) Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269, 540-543.
-
(1995)
Science
, vol.269
, pp. 540-543
-
-
Pelleymounter, M.A.1
Cullen, M.J.2
Baker, M.B.3
Hecht, R.4
Winters, D.5
Boone, T.6
Collins, F.7
-
2
-
-
0029048408
-
Recombinant mouse ob protein: Evidence for a peripheral signal linking adiposity and central neural networks
-
Campfield, L. A., Smith, F. J., Guisez, Y., Devos, R., and Burn, P. (1995) Recombinant mouse ob protein: Evidence for a peripheral signal linking adiposity and central neural networks. Science 269, 546-548.
-
(1995)
Science
, vol.269
, pp. 546-548
-
-
Campfield, L.A.1
Smith, F.J.2
Guisez, Y.3
Devos, R.4
Burn, P.5
-
3
-
-
0029131574
-
Expression of ob mRNA and its encoded protein in rodents: Impact of nutrition and obesity
-
Frederich, R. C., Lollmann, B., Hamann, A., Napolitano-Rosen, A., Kahn, B. B., Lowell, B. B., and Flier, J. S. (1995) Expression of ob mRNA and its encoded protein in rodents: impact of nutrition and obesity. J. Clin. Invest. 96, 1658-1663.
-
(1995)
J. Clin. Invest.
, vol.96
, pp. 1658-1663
-
-
Frederich, R.C.1
Lollmann, B.2
Hamann, A.3
Napolitano-Rosen, A.4
Kahn, B.B.5
Lowell, B.B.6
Flier, J.S.7
-
4
-
-
0032558725
-
Leptin and the regulation of body weight in mammals
-
Friedman, J. M., and Halaas, J. L. (1998) Leptin and the regulation of body weight in mammals. Science 395, 763-770.
-
(1998)
Science
, vol.395
, pp. 763-770
-
-
Friedman, J.M.1
Halaas, J.L.2
-
5
-
-
0030866843
-
Nonsdipose tissue production of leptin: Leptin as a novel placenta-derived hormone in humans
-
Masuzaki, H., Ogawa, Y., Sagawa, N., Hosoda, K., Matsumoto, T., Mise, H., Nishimura, H., Yoshimasa, Y., Tanaka, I., Mori, T., and Nakao, K. (1997) Nonsdipose tissue production of leptin: Leptin as a novel placenta-derived hormone in humans. Nature Med. 3, 1029-1033.
-
(1997)
Nature Med.
, vol.3
, pp. 1029-1033
-
-
Masuzaki, H.1
Ogawa, Y.2
Sagawa, N.3
Hosoda, K.4
Matsumoto, T.5
Mise, H.6
Nishimura, H.7
Yoshimasa, Y.8
Tanaka, I.9
Mori, T.10
Nakao, K.11
-
6
-
-
0031590603
-
Leptin production by hydatidiform mole
-
Sagawa, N, Mori, T., Masuzaki, H., Ogawa, Y., and Nakao, K. (1997) Leptin production by hydatidiform mole. Lancet 22, 1518-1519.
-
(1997)
Lancet
, vol.22
, pp. 1518-1519
-
-
Sagawa, N.1
Mori, T.2
Masuzaki, H.3
Ogawa, Y.4
Nakao, K.5
-
7
-
-
2442654859
-
Identification and expression cloning of a leptin receptor, OB-R
-
Tartaglia, L. A., Dembski, M., Weng, X., Dengn, N., Culpepper, J., Devos, R., Richards, G. J., Campfield, L. A., Clark, F. T., Deeds, J., Muir, C., Sanker, S., Moriarty, A., Moore, K. J., Smutko, J. S., Mays, G. G., Woolf, E. A., Monroe, C. A., and Tepper, R. I. (1995) Identification and expression cloning of a leptin receptor, OB-R. Cell 83, 1263-1271.
-
(1995)
Cell
, vol.83
, pp. 1263-1271
-
-
Tartaglia, L.A.1
Dembski, M.2
Weng, X.3
Dengn, N.4
Culpepper, J.5
Devos, R.6
Richards, G.J.7
Campfield, L.A.8
Clark, F.T.9
Deeds, J.10
Muir, C.11
Sanker, S.12
Moriarty, A.13
Moore, K.J.14
Smutko, J.S.15
Mays, G.G.16
Woolf, E.A.17
Monroe, C.A.18
Tepper, R.I.19
-
8
-
-
0030807358
-
Diet-induced obese mice develop peripheral, but not central, resistance to leptin
-
Van Heek, M., Compton, D. S., France, C. F., Tedesco, R. P., Fawzi, A. B., Graziano, M. P., Sybertz, E. J., Strader, C. D., and Davis, H. R., Jr. (1997) Diet-induced obese mice develop peripheral, but not central, resistance to leptin. J. Clin. Invest. 99, 385-390.
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 385-390
-
-
Van Heek, M.1
Compton, D.S.2
France, C.F.3
Tedesco, R.P.4
Fawzi, A.B.5
Graziano, M.P.6
Sybertz, E.J.7
Strader, C.D.8
Davis H.R., Jr.9
-
9
-
-
0031906674
-
Leptin activates distinct projections from the dorsomedial and ventromedial hypothalamic nuclei
-
Elmquist, J. K., Ahima, R., Elias, C., Elier, J. S., and Saper, C. B. (1998) Leptin activates distinct projections from the dorsomedial and ventromedial hypothalamic nuclei. Proc. Natl. Acad. Sci. USA 95, 741-746.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 741-746
-
-
Elmquist, J.K.1
Ahima, R.2
Elias, C.3
Elier, J.S.4
Saper, C.B.5
-
10
-
-
0030039272
-
Abnormal splicing of the leptin receptor in diabetic mice
-
Lee, G. H., Proenca, R., Montez, J. M., Carrol, K. M., Darvishzadeh, J. G., Lee, J. I., and Friedman, J. M. (1996) Abnormal splicing of the leptin receptor in diabetic mice. Nature 379, 632-635.
-
(1996)
Nature
, vol.379
, pp. 632-635
-
-
Lee, G.H.1
Proenca, R.2
Montez, J.M.3
Carrol, K.M.4
Darvishzadeh, J.G.5
Lee, J.I.6
Friedman, J.M.7
-
11
-
-
0030015417
-
Defective STAT signaling by the leptin receptor in diabetic mice
-
Ghilardi, N., Ziegler, S., Wiestner, A., Stoffel, R., Heim, M. H., and Skoda, R. (1996) Defective STAT signaling by the leptin receptor in diabetic mice. Proc. Natl. Acad. Sci. USA 93, 6231-6235.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 6231-6235
-
-
Ghilardi, N.1
Ziegler, S.2
Wiestner, A.3
Stoffel, R.4
Heim, M.H.5
Skoda, R.6
-
12
-
-
0031436148
-
Divergent signaling capacities of the long and short isoforms of the leptin receptor
-
Bjorbaek, C., Uotani, S., de Silva, B., and Flier, J. S. (1997) Divergent signaling capacities of the long and short isoforms of the leptin receptor. J. Biol. Chem. 272, 32686-32695.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 32686-32695
-
-
Bjorbaek, C.1
Uotani, S.2
De Silva, B.3
Flier, J.S.4
-
13
-
-
0033082426
-
Feeding and body-weight regulation by hypothalamic neuropeptides - Mediation of the actions of leptin
-
Inui, A. (1999) Feeding and body-weight regulation by hypothalamic neuropeptides - Mediation of the actions of leptin. Trends Neurosci. 22, 62-67.
-
(1999)
Trends Neurosci.
, vol.22
, pp. 62-67
-
-
Inui, A.1
-
14
-
-
0029881125
-
Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans
-
Schwartz, M. W., Peskind, E., Raskind, M., Boyko, E. J., and Porte, D., Jr. (1996) Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans. Nature Med. 2, 589-593.
-
(1996)
Nature Med.
, vol.2
, pp. 589-593
-
-
Schwartz, M.W.1
Peskind, E.2
Raskind, M.3
Boyko, E.J.4
Porte D., Jr.5
-
15
-
-
0030594830
-
Decreased cerebrospinal-fluid/serum leptin ratio in obesity: A possible mechanism for leptin resistance
-
Caro, J. F., Kolaczynski, J. W., Nyce, M. R., Ohannesian, J. P., Opentanova, I., Goldman, W. H., Lynn, R. B., Zhang, P.-L., Sinha, M. K., and Considine, R. V. (1996) Decreased cerebrospinal-fluid/serum leptin ratio in obesity: A possible mechanism for leptin resistance. Lancet 348, 159-161.
-
(1996)
Lancet
, vol.348
, pp. 159-161
-
-
Caro, J.F.1
Kolaczynski, J.W.2
Nyce, M.R.3
Ohannesian, J.P.4
Opentanova, I.5
Goldman, W.H.6
Lynn, R.B.7
Zhang, P.-L.8
Sinha, M.K.9
Considine, R.V.10
-
16
-
-
0032577376
-
Signals that regulate food intake and energy homeostasis
-
Woods, S. C., Seeley, R. J., Porte, D., Jr., and Schwartz, L. A. (1998) Signals that regulate food intake and energy homeostasis. Science 280, 1378-1383.
-
(1998)
Science
, vol.280
, pp. 1378-1383
-
-
Woods, S.C.1
Seeley, R.J.2
Porte D., Jr.3
Schwartz, L.A.4
-
17
-
-
15444339427
-
Obesity, diabetes, and the central nervous system
-
Porte, D., Jr., Seeley, R. J., Woods, S. C., Baskin, D. G., Figlewicz D. P., and Schwartz, M. W. (1998) Obesity, diabetes, and the central nervous system. Diabetologia 41, 863-881.
-
(1998)
Diabetologia
, vol.41
, pp. 863-881
-
-
Porte D., Jr.1
Seeley, R.J.2
Woods, S.C.3
Baskin, D.G.4
Figlewicz, D.P.5
Schwartz, M.W.6
-
18
-
-
0032749335
-
Expression of LR11, a mosaic LDL receptor family member, is markedly increased in atherosclerotic lesions
-
Kanaki, T., Bujo, H., Hirayama, S., Ishii, I., Morisaki, N., Schneider, W. J., and Saito, Y. (1999) Expression of LR11, a mosaic LDL receptor family member, is markedly increased in atherosclerotic lesions. Arterioscler. Thromb. Vasc. Biol. 19, 2687-2695.
-
(1999)
Arterioscler. Thromb. Vasc. Biol.
, vol.19
, pp. 2687-2695
-
-
Kanaki, T.1
Bujo, H.2
Hirayama, S.3
Ishii, I.4
Morisaki, N.5
Schneider, W.J.6
Saito, Y.7
-
19
-
-
0242437092
-
A novel mosaic protein containing LDL receptor elements is highly conserved in humans and chickens
-
Moerwald, S., Yamazaki, H., Bujo, H., Kusunoki, J., Kanaki, T., Seimiya, K., Morisaki, N., Nimpf, J., Schneider, W. J., and Saito, Y. (1997) A novel mosaic protein containing LDL receptor elements is highly conserved in humans and chickens. Arterioscler. Thromb. Vasc. Biol. 17, 996-1002.
-
(1997)
Arterioscler. Thromb. Vasc. Biol.
, vol.17
, pp. 996-1002
-
-
Moerwald, S.1
Yamazaki, H.2
Bujo, H.3
Kusunoki, J.4
Kanaki, T.5
Seimiya, K.6
Morisaki, N.7
Nimpf, J.8
Schneider, W.J.9
Saito, Y.10
-
20
-
-
0027946911
-
Chicken oocyte growth is mediated by an eight ligand binding repeat member of the LDL receptor family
-
Bujo, H., Hermann, M., Kaderli, M. O., Jacobsen, L., Sugawara, S., Nimpf, J., Yamamoto, T., and Schneider, W. J. (1994) Chicken oocyte growth is mediated by an eight ligand binding repeat member of the LDL receptor family. EMBO J. 13, 5165-5175.
-
(1994)
EMBO J.
, vol.13
, pp. 5165-5175
-
-
Bujo, H.1
Hermann, M.2
Kaderli, M.O.3
Jacobsen, L.4
Sugawara, S.5
Nimpf, J.6
Yamamoto, T.7
Schneider, W.J.8
-
21
-
-
0003903343
-
-
Cold Spring Harbor Laboratory Press, Plainview, NY
-
Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory Press, Plainview, NY.
-
(1989)
Molecular Cloning: A Laboratory Manual
-
-
Sambrook, J.1
Fritsch, E.F.2
Maniatis, T.3
-
22
-
-
0032527071
-
Distributions of leptin receptor mRNA isoforms in the rat brain
-
Elmquist, J. K., Bjorbaek, C., Ahima, R. S., Fkier, J. S., and Saper, C. B. (1998) Distributions of leptin receptor mRNA isoforms in the rat brain. J. Comp. Neurol. 395, 535-547.
-
(1998)
J. Comp. Neurol.
, vol.395
, pp. 535-547
-
-
Elmquist, J.K.1
Bjorbaek, C.2
Ahima, R.S.3
Fkier, J.S.4
Saper, C.B.5
-
23
-
-
0031975670
-
Differential expression and regulation of leptin receptor isoforms in the rat brain: Effects of fasting and estrogen
-
Bennet, P. A., Lindell, K., Karlsson, C., Robinson, I. C. A. F., Carlson, L. N. S., and Carlson, B. (1998) differential expression and regulation of leptin receptor isoforms in the rat brain: Effects of fasting and estrogen. Neuroendocrinology 67, 29-36.
-
(1998)
Neuroendocrinology
, vol.67
, pp. 29-36
-
-
Bennet, P.A.1
Lindell, K.2
Karlsson, C.3
Robinson, I.C.A.F.4
Carlson, L.N.S.5
Carlson, B.6
-
24
-
-
0031761385
-
Expression of leptin receptor isoforms in rat brain microvessels
-
Bjorbaek, C., Elmquist, J. K., Michl, P., Ahima, R. S., van Bueren, A., McCall, A. L., and Flier, J. S. (1998) Expression of leptin receptor isoforms in rat brain microvessels. Endocrinology 139, 3485-3491.
-
(1998)
Endocrinology
, vol.139
, pp. 3485-3491
-
-
Bjorbaek, C.1
Elmquist, J.K.2
Michl, P.3
Ahima, R.S.4
Van Bueren, A.5
McCall, A.L.6
Flier, J.S.7
-
25
-
-
0029895421
-
Phenotype-linked amino acid alteration in leptin receptor cDNA from Zucker fatty (fa/fa) rat
-
Iida, M., Murakami, T., Ishida, K., Mizuno, A., Kuwajima, M., and Shima, K. (1996) Phenotype-linked amino acid alteration in leptin receptor cDNA from Zucker fatty (fa/fa) rat. Biochem. Biophys. Res. Commun. 222, 19-26.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.222
, pp. 19-26
-
-
Iida, M.1
Murakami, T.2
Ishida, K.3
Mizuno, A.4
Kuwajima, M.5
Shima, K.6
-
26
-
-
0031887488
-
Immunohistochemical localization of leptin receptor in the rat brain
-
Shioda, S., Funahashi, H., Hakajo, S., Yada, T., Maruta, O., and Nakai, Y. (1998) Immunohistochemical localization of leptin receptor in the rat brain. Neurosci. Lett. 243, 41-44.
-
(1998)
Neurosci. Lett.
, vol.243
, pp. 41-44
-
-
Shioda, S.1
Funahashi, H.2
Hakajo, S.3
Yada, T.4
Maruta, O.5
Nakai, Y.6
-
27
-
-
0031010408
-
Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues
-
Fei, H., Okano, H. J., Li, C., Lee, G. H., Zhao, C., Darnell, R., and Friedman, J. M. (1997) Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues. Proc. Natl. Acad. Sci. USA 94, 7001-7005.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 7001-7005
-
-
Fei, H.1
Okano, H.J.2
Li, C.3
Lee, G.H.4
Zhao, C.5
Darnell, R.6
Friedman, J.M.7
-
28
-
-
0030806382
-
Localization of leptin receptor in the human brain
-
Couce, M. E., Burguera, B., Parist, J. E., Jensen, M. D., and Lloyd, R. V. (1997) Localization of leptin receptor in the human brain. Neuroendocrinology 66, 145-150.
-
(1997)
Neuroendocrinology
, vol.66
, pp. 145-150
-
-
Couce, M.E.1
Burguera, B.2
Parist, J.E.3
Jensen, M.D.4
Lloyd, R.V.5
-
29
-
-
85011452023
-
Localization of leptin receptor (Ob-R) messenger ribonucleic acid in the rodent hindbrain
-
Mercer, J. G., Moar, K. M., and Hoggard, N. (1998) Localization of leptin receptor (Ob-R) messenger ribonucleic acid in the rodent hindbrain. Endocrinology 139, 29-34.
-
(1998)
Endocrinology
, vol.139
, pp. 29-34
-
-
Mercer, J.G.1
Moar, K.M.2
Hoggard, N.3
-
30
-
-
0030726287
-
Differential expression of mRNA for leptin receptor isoforms in the rat brain
-
Guan, X.-M., Hess, J. F., Yu, H., Hey, P. J., and van der Ploeg, L. H. T. (1997) Differential expression of mRNA for leptin receptor isoforms in the rat brain. Mol. Cell. Endocrinol. 133, 1-7.
-
(1997)
Mol. Cell. Endocrinol.
, vol.133
, pp. 1-7
-
-
Guan, X.-M.1
Hess, J.F.2
Yu, H.3
Hey, P.J.4
Van Der Ploeg, L.H.T.5
-
31
-
-
0029895233
-
Localozation of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization
-
Mercer, J. G., Hoggard, N., Williams, L. M., Lawrence, C. B., Hannah, L. T., and Trayhurn, P. (1996) Localozation of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization. FEBS Lett. 387, 113-116.
-
(1996)
FEBS Lett.
, vol.387
, pp. 113-116
-
-
Mercer, J.G.1
Hoggard, N.2
Williams, L.M.3
Lawrence, C.B.4
Hannah, L.T.5
Trayhurn, P.6
-
32
-
-
0030768058
-
Expression of leptin receptor mRNA (long form splice variant) in the human cerebellum
-
Savioz, A., Charnay, Y., Huguenin, C., Graviou, C., Greggio, B., and Bouras, C. (1997) Expression of leptin receptor mRNA (long form splice variant) in the human cerebellum. NeuroReport 8, 3123-3126.
-
(1997)
NeuroReport
, vol.8
, pp. 3123-3126
-
-
Savioz, A.1
Charnay, Y.2
Huguenin, C.3
Graviou, C.4
Greggio, B.5
Bouras, C.6
-
33
-
-
0030669288
-
Inhibition of food response to intracerebroventricular injection of leptin is attenuated in rats with diet-induced obesity
-
Widdowson, P. S., Buckingham, U. R., Arch, J., and Williams, G. (1997) Inhibition of food response to intracerebroventricular injection of leptin is attenuated in rats with diet-induced obesity. Diabetes 46, 1782-1785.
-
(1997)
Diabetes
, vol.46
, pp. 1782-1785
-
-
Widdowson, P.S.1
Buckingham, U.R.2
Arch, J.3
Williams, G.4
-
34
-
-
85011479697
-
Upregulation of leptin receptor-gene expression in the anterior pituitary of human growth hormone-releasing hormone transgenic mice
-
Cai, A., and Hyde, J. F. (1997) Upregulation of leptin receptor-gene expression in the anterior pituitary of human growth hormone-releasing hormone transgenic mice. Endocrinology 139, 420-423.
-
(1997)
Endocrinology
, vol.139
, pp. 420-423
-
-
Cai, A.1
Hyde, J.F.2
-
35
-
-
0023865299
-
Insulin and insulin-like growth factors in the CNS
-
Baskin, D. G., Wilcox, B. J., Figlewicz, D. P., and Dorsa, D. M. (1988) Insulin and insulin-like growth factors in the CNS. Trends Neurosci. 11, 107-111.
-
(1988)
Trends Neurosci.
, vol.11
, pp. 107-111
-
-
Baskin, D.G.1
Wilcox, B.J.2
Figlewicz, D.P.3
Dorsa, D.M.4
-
36
-
-
0028348778
-
Insulin receptor substrate-1 (IRS-1) expression in rat brain
-
Baskin, D. G., Schwartz, M. W., Sipols, A. J., D'alessio, D. A., Goldstein, B. J., and White, M. F. (1994) Insulin receptor substrate-1 (IRS-1) expression in rat brain. Endocrinology 134, 1952-1955.
-
(1994)
Endocrinology
, vol.134
, pp. 1952-1955
-
-
Baskin, D.G.1
Schwartz, M.W.2
Sipols, A.J.3
D'alessio, D.A.4
Goldstein, B.J.5
White, M.F.6
-
37
-
-
85044012045
-
Insulin and insulin-like growth factor-1 stimulate a common endogenous phosphoprotein substrate (pp185) in intact neuroblastoma cells
-
Schemer, J., Adamo, M., Wilson, G. L., Heffez, D., Zick, Y., and Leroith, D. (1987) Insulin and insulin-like growth factor-1 stimulate a common endogenous phosphoprotein substrate (pp185) in intact neuroblastoma cells. J. Biol. Chem. 262, 15476-15482.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 15476-15482
-
-
Schemer, J.1
Adamo, M.2
Wilson, G.L.3
Heffez, D.4
Zick, Y.5
Leroith, D.6
|