-
1
-
-
0029859099
-
Leptin: Tlie tale of an obesity gene
-
Caro JF, Sinha MK, Kolaczynski JW, Zhang PL, Considine RV: Leptin: Tlie tale of an obesity gene. Diabetes 1996;45:1455-1462.
-
(1996)
Diabetes
, vol.45
, pp. 1455-1462
-
-
Caro, J.F.1
Sinha, M.K.2
Kolaczynski, J.W.3
Zhang, P.L.4
Considine, R.V.5
-
2
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homolo-gue
-
Zhang Y, Proenca R, Maffcci M, Barone M, Leopold L, Friedman JM: Positional cloning of the mouse obese gene and its human homolo-gue. Nature 1994;372:425-432.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffcci, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
3
-
-
0029073613
-
Weight-reducing effects of the plasma protein encoded by the obese gene
-
Halaas JD, Gajiwala KS, Maffei M, Cohen SL, Chait BT, Rabinowitz D, Lallonc RL, Burley SK. Friedman JM: Weight-reducing effects of the plasma protein encoded by the obese gene. Science 1995;269:543-546.
-
(1995)
Science
, vol.269
, pp. 543-546
-
-
Halaas, J.D.1
Gajiwala, K.S.2
Maffei, M.3
Cohen, S.L.4
Chait, B.T.5
Rabinowitz, D.6
Lallonc, R.L.7
Burley, S.K.8
Friedman, J.M.9
-
4
-
-
0029066265
-
Effects of the obese gene product on body weight regulation in ob/ob mice
-
Pcllcymounter MA, Culen MJ, Baker MB, Hecht R, Winters D, Boone T, Collins F: Effects of the obese gene product on body weight regulation in ob/ob mice. Science 1995:269: 540-543.
-
(1995)
Science
, vol.269
, pp. 540-543
-
-
Pcllcymounter, M.A.1
Culen, M.J.2
Baker, M.B.3
Hecht, R.4
Winters, D.5
Boone, T.6
Collins, F.7
-
5
-
-
0029048408
-
Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity to central neural networks
-
Campfield LA, Smith FJ, Guisez Y, Devos R, Bum P: Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity to central neural networks. Science 1995:269: 546-549.
-
(1995)
Science
, vol.269
, pp. 546-549
-
-
Campfield, L.A.1
Smith, F.J.2
Guisez, Y.3
Devos, R.4
Bum, P.5
-
6
-
-
2442654859
-
Identification and expression cloning of a leptin receptor OB-R
-
Tartaglia LA, Dembski M, Weng X, Deng N, Culpepper J, Devos R, Richards GJ, Camp-field LA, Clark FT, Deeds J, Muir C, Sanker S, Moriarty A, Moore KJ, Smutko JS, Mays GG, Woolf EA, Monroe CA, Tcpper RI: Identification and expression cloning of a leptin receptor OB-R. Cell 1995;83:1263-1271.
-
(1995)
Cell
, vol.83
, pp. 1263-1271
-
-
Tartaglia, L.A.1
Dembski, M.2
Weng, X.3
Deng, N.4
Culpepper, J.5
Devos, R.6
Richards, G.J.7
Camp-Field, L.A.8
Clark, F.T.9
Deeds, J.10
Muir, C.11
Sanker, S.12
Moriarty, A.13
Moore, K.J.14
Smutko, J.S.15
Mays, G.G.16
Woolf, E.A.17
Monroe, C.A.18
Tcpper, R.I.19
-
7
-
-
0029864416
-
Leptin enters the brain by a saturable system independent of insulin
-
Banks WA, Kastin AJ, Huang W, Jaspan JB, Maness LM: Leptin enters the brain by a saturable system independent of insulin. Peptides 1996;17:305-311.
-
(1996)
Peptides
, vol.17
, pp. 305-311
-
-
Banks, W.A.1
Kastin, A.J.2
Huang, W.3
Jaspan, J.B.4
Maness, L.M.5
-
8
-
-
0029986894
-
Localization of binding sites in the central nervous system for leptin (OB protein) in normal, obese (ob/ob) and diabetic (db/db) C57BLL/6J mice
-
Malik KF, Young WS: Localization of binding sites in the central nervous system for leptin (OB protein) in normal, obese (ob/ob) and diabetic (db/db) C57BLL/6J mice. Endocrinology 1996;137:1497-1500.
-
(1996)
Endocrinology
, vol.137
, pp. 1497-1500
-
-
Malik, K.F.1
Young, W.S.2
-
9
-
-
0031054014
-
Leptin activates neurons in ven-trobasal hypothalamus and brainstem
-
Elniquist JK, Ahima RS, Maratos-Flier E, Flier JS, Saper CB: Leptin activates neurons in ven-trobasal hypothalamus and brainstem. Endocrinology 1996:138:839-842.
-
(1996)
Endocrinology
, vol.138
, pp. 839-842
-
-
Elniquist, J.K.1
Ahima, R.S.2
Maratos-Flier, E.3
Flier, J.S.4
Saper, C.B.5
-
10
-
-
0030942844
-
The leptin receptor
-
Tartaglia LA: The leptin receptor. J Biol Chem 1997;272:6093-6096.
-
(1997)
J Biol Chem
, vol.272
, pp. 6093-6096
-
-
Tartaglia, L.A.1
-
11
-
-
13344259300
-
Tepper Rl. Morgenstcn JP: Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/ db mice
-
Chen H, Charlat O, Tartaglia LA, Woolf EA, Weng X, Ellis SJ, Lakey ND, Culpepper J. Moore KJ. Breitbart RE. Duvk GM, Tepper Rl. Morgenstcn JP: Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/ db mice. Cell 1996:84:491-495.
-
(1996)
Cell
, vol.84
, pp. 491-495
-
-
Chen, H.1
Charlat, O.2
Tartaglia, L.A.3
Woolf, E.A.4
Weng, X.5
Ellis, S.J.6
Lakey, N.D.7
Culpepper, J.8
Moore, K.J.9
Breitbart, R.E.10
Duvk, G.M.11
-
12
-
-
0030028959
-
Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (Leptin) receptor
-
Chua SC, Chung WK, Wu-Peng XS, Zhang Y, Lui SM, Tartaglia L, Leibel RL: Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor. Science 1996:271: 994-999.
-
(1996)
Science
, vol.271
, pp. 994-999
-
-
Chua, S.C.1
Chung, W.K.2
Wu-Peng, X.S.3
Zhang, Y.4
Lui, S.M.5
Tartaglia, L.6
Leibel, R.L.7
-
13
-
-
0030039272
-
Abnormal splicing of the leptin receptor in diabetic mice
-
Lee GH, Proenca R, Montez JM, Carroll KM, Darvishzadeh JG, Lee JI, Friedman JM: Abnormal splicing of the leptin receptor in diabetic mice. Nature 1996;379:632-635.
-
(1996)
Nature
, vol.379
, pp. 632-635
-
-
Lee, G.H.1
Proenca, R.2
Montez, J.M.3
Carroll, K.M.4
Darvishzadeh, J.G.5
Lee, J.I.6
Friedman, J.M.7
-
14
-
-
0029776030
-
The full-length leptin receptor has signaling capabilities of interleukin-6-lype cytokine receptors
-
Baumann H, Morelia KK, White DW, Dembski M, Bailon PS, Kim H, Lai CF, Tartaglia LA: The full-length leptin receptor has signaling capabilities of interleukin-6-lype cytokine receptors. Proc Natl Acad Sei USA 1996:93: 8374-8378.
-
(1996)
Proc Natl Acad Sei USA
, vol.93
, pp. 8374-8378
-
-
Baumann, H.1
Morelia, K.K.2
White, D.W.3
Dembski, M.4
Bailon, P.S.5
Kim, H.6
Lai, C.F.7
Tartaglia, L.A.8
-
15
-
-
0029739826
-
Leptin activation of Stat-3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice
-
Vaisse C, Halaas JL, Horvath CM, Darnell JE Jr, Stoffel M, Friedman JM: Leptin activation of Stat-3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice. Nat Genet 1996;14:95-97.
-
(1996)
Nat Genet
, vol.14
, pp. 95-97
-
-
Vaisse, C.1
Halaas, J.L.2
Horvath, C.M.3
Darnell, J.E.4
Stoffel, M.5
Friedman, J.M.6
-
16
-
-
0029739970
-
Identification of targets of leptin action in rat hypothalamus
-
Schwartz MW, Seeley RJ, Campfield LA, Burn P. Baskin DG: Identification of targets of leptin action in rat hypothalamus. J Clin Invest 1996: 98:1101-1106.
-
(1996)
J Clin Invest
, vol.98
, pp. 1101-1106
-
-
Schwartz, M.W.1
Seeley, R.J.2
Campfield, L.A.3
Burn, P.4
Baskin, D.G.5
-
17
-
-
0029098589
-
The role of neuropeptide Y in the antiobesity action of the obese gene product
-
Stephens TW, Basinski M, Bristow PK, Bue-Valleskey JM. Burgett SG. Cratf L, Hale J, Hoffman J, Hsiung HM, Kriauciunas A, MacKellar W. Rostec PR, Schoner B, Smith D, Tinsley FC, Zang X-Y, Heiman M: The role of neuropeptide Y in the antiobesity action of the obese gene product. Nature 1995;377:530-532.
-
(1995)
Nature
, vol.377
, pp. 530-532
-
-
Stephens, T.W.1
Basinski, M.2
Bristow, P.K.3
Bue-Valleskey, J.M.4
Burgett, S.G.5
Cratf, L.6
Hale, J.7
Hoffman, J.8
Hsiung, H.M.9
Kriauciunas, A.10
Mackellar, W.11
Rostec, P.R.12
Schoner, B.13
Smith, D.14
Tinsley, F.C.15
Zang, X.-Y.16
Heiman, M.17
-
18
-
-
0029980118
-
Ob protein binds specifically to the choroid plexus of mice and rats
-
Devos R, Richards JG. Campfield LA. Tartaglia LA, Guisez Y, Van der Heyden J, Travcr-nier J, Platinck G. Burn P: Ob protein binds specifically to the choroid plexus of mice and rats. Proc Natl Acad Sei USA 1996;93:5668-5673.
-
(1996)
Proc Natl Acad Sei USA
, vol.93
, pp. 5668-5673
-
-
Devos, R.1
Richards, J.G.2
Campfield, L.A.3
Tartaglia, L.A.4
Guisez, Y.5
Van Der Heyden, J.6
Travcr-Nier, J.7
Platinck, G.8
Burn, P.9
-
19
-
-
0007524724
-
Evidence of free and bound leptin in human circulation
-
Sinha MK, Opentanova I, Ohannesian JP, Kolaczynski JW, Heiman ML, Hale J, Becker GW, Bowsher RR, Stephens TW, Caro JF: Evidence of free and bound leptin in human circulation. J Clin Invest 1996;98:1277-1282.
-
(1996)
J Clin Invest
, vol.98
, pp. 1277-1282
-
-
Sinha, M.K.1
Opentanova, I.2
Ohannesian, J.P.3
Kolaczynski, J.W.4
Heiman, M.L.5
Hale, J.6
Becker, G.W.7
Bowsher, R.R.8
Stephens, T.W.9
Caro, J.F.10
-
20
-
-
0024507270
-
Effects of estradiol on prolactin and growth hormone messenger RNAs in cultured normal and neoplastic (MtT/ W15 and GH3) rat pituitary cells
-
Song JY, Jin L, Lloyd RV: Effects of estradiol on prolactin and growth hormone messenger RNAs in cultured normal and neoplastic (MtT/ W15 and GH3) rat pituitary cells. Cancer Res 1989;49:1247-1253.
-
(1989)
Cancer Res
, vol.49
, pp. 1247-1253
-
-
Song, J.Y.1
Jin, L.2
Lloyd, R.V.3
-
21
-
-
0029016228
-
Streptozotocin-induced diabetes alters protein kinase C isoforms in rat hippocampal neurons
-
Coucc ME, Smith AW, Ways DK, McGinty JF: Streptozotocin-induced diabetes alters protein kinase C isoforms in rat hippocampal neurons. Endocrinol Metab 1995;2:135-146.
-
(1995)
Endocrinol Metab
, vol.2
, pp. 135-146
-
-
Coucc, M.E.1
Smith, A.W.2
Ways, D.K.3
McGinty, J.F.4
-
22
-
-
0029885220
-
The hypothalamic leptin receptor in humans
-
Considine RV, Considine EL, Williams CJ, Hyde TM, Caro JF: The hypothalamic leptin receptor in humans. Diabetes 1996; 19:992-994.
-
(1996)
Diabetes
, vol.19
, pp. 992-994
-
-
Considine, R.V.1
Considine, E.L.2
Williams, C.J.3
Hyde, T.M.4
Caro, J.F.5
-
23
-
-
0029881125
-
Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans
-
Schwartz MW. Peskind E. Raskind M. Boyko EJ, Porte D: Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans. Nat Med 1996;2:589-589.
-
(1996)
Nat Med
, vol.2
, pp. 589
-
-
Schwartz, M.W.1
Boyko, E.J.2
Porte, D.3
-
25
-
-
0030594830
-
Decreased cerebrospinal-fluid/scrum leptin ratio in obesity: A possible mechanism for leptin resistance
-
Caro JF, Kolaczynski JW, Nycc MR, Ohannesian JP, Opentanova I, Goldman WH, Lynn RB, Zhang PL, Sinha MK, Considine RV: Decreased cerebrospinal-fluid/scrum leptin ratio in obesity: A possible mechanism for leptin resistance. Lancet 1996;348:159-161.
-
(1996)
Lancet
, vol.348
, pp. 159-161
-
-
Caro, J.F.1
Kolaczynski, J.W.2
Nycc, M.R.3
Ohannesian, J.P.4
Opentanova, I.5
Goldman, W.H.6
Lynn, R.B.7
Zhang, P.L.8
Sinha, M.K.9
Considine, R.V.10
-
26
-
-
0029949063
-
Leptin activation in hypothalamus
-
Woods AJ, Stock MJ: Leptin activation in hypothalamus. Nature 1996;381:745.
-
(1996)
Nature
, vol.381
, pp. 745
-
-
Woods, A.J.1
Stock, M.J.2
-
27
-
-
0031019079
-
Expression and localization of the leptin receptor in endocrine and neuroendocrine tissues of the rat
-
Zamorano PL, Mahesh VB, DeSevilla LM, Chorich LP, Bhat GK, Brann DW: Expression and localization of the leptin receptor in endocrine and neuroendocrine tissues of the rat. Neuroendocrinology 1997;65:223-228.
-
(1997)
Neuroendocrinology
, vol.65
, pp. 223-228
-
-
Zamorano, P.L.1
Mahesh, V.B.2
Desevilla, L.M.3
Chorich, L.P.4
Bhat, G.K.5
Brann, D.W.6
-
28
-
-
0027937749
-
Weight loss in Alzheimer’s disease, an international review of the literature
-
Wolf-Klein GP, Silverstone FA: Weight loss in Alzheimer’s disease, an international review of the literature. Int Psychogeriatr 1994:6:135-142.
-
(1994)
Int Psychogeriatr
, vol.6
, pp. 135-142
-
-
Wolf-Klein, G.P.1
Silverstone, F.A.2
-
29
-
-
0030956390
-
The leptin receptor activates Janus kinase 2 and signals for proliferation in a factor-dependent cell line
-
Ghilardi N, Skoda RC: The leptin receptor activates Janus kinase 2 and signals for proliferation in a factor-dependent cell line. Mol Endocrinol 1997;11:393-399.
-
(1997)
Mol Endocrinol
, vol.11
, pp. 393-399
-
-
Ghilardi, N.1
Skoda, R.C.2
|