-
1
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM: Positional cloning of the mouse obese gene and its human homologue. Nature 1994;372:425-432.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
2
-
-
0015792424
-
Effects of parabiosis of obese with diabetes and normal mice
-
Coleman DL: Effects of parabiosis of obese with diabetes and normal mice. Diabetologia 1973;9:294-298.
-
(1973)
Diabetologia
, vol.9
, pp. 294-298
-
-
Coleman, D.L.1
-
3
-
-
0029859099
-
Leptin: The tale of an obesity gene
-
Caro JF, Sinha MK, Kolaczynski JW, Zhang PL, Considine RV: Leptin: The tale of an obesity gene. Diabetes 1996;45:1455-1462.
-
(1996)
Diabetes
, vol.45
, pp. 1455-1462
-
-
Caro, J.F.1
Sinha, M.K.2
Kolaczynski, J.W.3
Zhang, P.L.4
Considine, R.V.5
-
4
-
-
0030902584
-
Leptin expression and action: New experimental paradigms
-
Flier JS: Leptin expression and action: New experimental paradigms. Proc Natl Acad Sci USA 1997;94:4242-4245.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 4242-4245
-
-
Flier, J.S.1
-
5
-
-
0030467446
-
The ob protein (leptin) pathway - A link between adipose tissue mass and central neural networks
-
Campfield LA, Smith FJ, Burn P: The ob protein (leptin) pathway - A link between adipose tissue mass and central neural networks. Horm Metab Res 1996;28:619-632.
-
(1996)
Horm Metab Res
, vol.28
, pp. 619-632
-
-
Campfield, L.A.1
Smith, F.J.2
Burn, P.3
-
6
-
-
0029896530
-
Role of leptin in the neuroendocrine response to fasting
-
Ahima RS, Prabakaran D, Mantzoros C, Qu D, Lowell B, Maratos-Flier E, Flier JS: Role of leptin in the neuroendocrine response to fasting. Nature 1996;382:250-252.
-
(1996)
Nature
, vol.382
, pp. 250-252
-
-
Ahima, R.S.1
Prabakaran, D.2
Mantzoros, C.3
Qu, D.4
Lowell, B.5
Maratos-Flier, E.6
Flier, J.S.7
-
7
-
-
0030010388
-
Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin
-
Chehab FF, Lim ME, Lu R: Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin. Nat Genet 1996;12:318-320.
-
(1996)
Nat Genet
, vol.12
, pp. 318-320
-
-
Chehab, F.F.1
Lim, M.E.2
Lu, R.3
-
8
-
-
0031014413
-
Early onset of reproductive function in normal female mice treated with leptin
-
Chehab FF, Mounzih K, Lu R, Lim ME: Early onset of reproductive function in normal female mice treated with leptin. Science 1997;275:88-90.
-
(1997)
Science
, vol.275
, pp. 88-90
-
-
Chehab, F.F.1
Mounzih, K.2
Lu, R.3
Lim, M.E.4
-
9
-
-
0030868077
-
Leptin accelerates the onset of puberty in normal female mice
-
Ahima RS, Dushay J, Flier SN, Prabakaran D, Flier JS: Leptin accelerates the onset of puberty in normal female mice. J Clin Invest 1997;99:391-395.
-
(1997)
J Clin Invest
, vol.99
, pp. 391-395
-
-
Ahima, R.S.1
Dushay, J.2
Flier, S.N.3
Prabakaran, D.4
Flier, J.S.5
-
10
-
-
0031057818
-
Leptin is a metabolic gate for the onset of puberty in the female rat
-
Cheung CC, Thornton JE, Kuijper JL, Weigle DS, Clifton DK, Steiner RA: Leptin is a metabolic gate for the onset of puberty in the female rat. Endocrinology 1997;138:855-858.
-
(1997)
Endocrinology
, vol.138
, pp. 855-858
-
-
Cheung, C.C.1
Thornton, J.E.2
Kuijper, J.L.3
Weigle, D.S.4
Clifton, D.K.5
Steiner, R.A.6
-
11
-
-
0030942844
-
The leptin receptor
-
Tartaglia LA: The leptin receptor. J Biol Chem 1997;272:6093-6096.
-
(1997)
J Biol Chem
, vol.272
, pp. 6093-6096
-
-
Tartaglia, L.A.1
-
12
-
-
0028117163
-
Cytokine signal transduction
-
Kishimoto T, Taga T, Akira S: Cytokine signal transduction. Cell 1994;76:253-262.
-
(1994)
Cell
, vol.76
, pp. 253-262
-
-
Kishimoto, T.1
Taga, T.2
Akira, S.3
-
13
-
-
2442654859
-
Identification and expression cloning of a leptin receptor, OB-R
-
Tartaglia LA, Dembski M, Weng X, Deng N, Culpepper J, Devos R, Richards GJ, Campfield LA, Clark FT, Deeds J, Muir C, Sanker S, Moriarty A, Moore KJ, Smutko JS, Mays GG, Woolf EA, Monroe CA, Tepper RI: Identification and expression cloning of a leptin receptor, OB-R. Cell 1995;83:1263-1271.
-
(1995)
Cell
, vol.83
, pp. 1263-1271
-
-
Tartaglia, L.A.1
Dembski, M.2
Weng, X.3
Deng, N.4
Culpepper, J.5
Devos, R.6
Richards, G.J.7
Campfield, L.A.8
Clark, F.T.9
Deeds, J.10
Muir, C.11
Sanker, S.12
Moriarty, A.13
Moore, K.J.14
Smutko, J.S.15
Mays, G.G.16
Woolf, E.A.17
Monroe, C.A.18
Tepper, R.I.19
-
14
-
-
0029739826
-
Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice
-
Vaisse C, Halaas JL, Horvath CM, Darnell JE Jr, Stoffel M, Friedman JM: Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice. Nat Genet 1996;14:95-97.
-
(1996)
Nat Genet
, vol.14
, pp. 95-97
-
-
Vaisse, C.1
Halaas, J.L.2
Horvath, C.M.3
Darnell Jr., J.E.4
Stoffel, M.5
Friedman, J.M.6
-
15
-
-
0031040793
-
Leptin receptor (OB-R) signaling: Cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerization
-
White DW, Kuropatwinski KK, Devos R, Baumann H, Tartaglia LA: Leptin receptor (OB-R) signaling: Cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerization. J Biol Chem 1997;272:4065-4071.
-
(1997)
J Biol Chem
, vol.272
, pp. 4065-4071
-
-
White, D.W.1
Kuropatwinski, K.K.2
Devos, R.3
Baumann, H.4
Tartaglia, L.A.5
-
16
-
-
0029864416
-
Leptin enters the brain by a saturable system independent of insulin
-
Banks WA, Kastin AJ, Huang W, Jaspan JB, Maness LM: Leptin enters the brain by a saturable system independent of insulin. Peptides 1996;17:305-311.
-
(1996)
Peptides
, vol.17
, pp. 305-311
-
-
Banks, W.A.1
Kastin, A.J.2
Huang, W.3
Jaspan, J.B.4
Maness, L.M.5
-
17
-
-
0031550523
-
A short form of leptin receptor performs signal transduction
-
Murakami T, Yamashita T, Iida M, Kuwajima M, Shima K: A short form of leptin receptor performs signal transduction. Biochem Biophys Res Commun 1997;231:26-29.
-
(1997)
Biochem Biophys Res Commun
, vol.231
, pp. 26-29
-
-
Murakami, T.1
Yamashita, T.2
Iida, M.3
Kuwajima, M.4
Shima, K.5
-
18
-
-
0031046730
-
Phenotype of the obese Koletsky (f) rat due to tyr763stop mutation in the extracellular domain of the leptin receptor (lepr): Evidence for deficient plasma-to-CSF transport of leptin in both the Zucker and Koletsky obese rat
-
Wu-Peng XS, Chua SC Jr, Okada N, Liu S-M, Nicolson M, Leibel RL: Phenotype of the obese Koletsky (f) rat due to tyr763stop mutation in the extracellular domain of the leptin receptor (lepr): Evidence for deficient plasma-to-CSF transport of leptin in both the Zucker and Koletsky obese rat. Diabetes 1997;46:513-518.
-
(1997)
Diabetes
, vol.46
, pp. 513-518
-
-
Wu-Peng, X.S.1
Chua Jr., S.C.2
Okada, N.3
Liu, S.-M.4
Nicolson, M.5
Leibel, R.L.6
-
19
-
-
13344259300
-
Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice
-
Chen H, Charlat O, Tartaglia LA, Woolf EA, Weng X, Ellis SJ, Lakey ND, Culpepper J, Moore KJ, Breitbart RE, Duyk GM, Tepper RI, Morgenstern JP: Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice. Cell 1996;84:491-495.
-
(1996)
Cell
, vol.84
, pp. 491-495
-
-
Chen, H.1
Charlat, O.2
Tartaglia, L.A.3
Woolf, E.A.4
Weng, X.5
Ellis, S.J.6
Lakey, N.D.7
Culpepper, J.8
Moore, K.J.9
Breitbart, R.E.10
Duyk, G.M.11
Tepper, R.I.12
Morgenstern, J.P.13
-
20
-
-
0030028959
-
Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor
-
Chua SC Jr, Chung WK, Wu-Peng XS, Zhang Y, Liu S-M, Tartaglia L, Leibel RL: Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor. Science 1996;271:994-996.
-
(1996)
Science
, vol.271
, pp. 994-996
-
-
Chua Jr., S.C.1
Chung, W.K.2
Wu-Peng, X.S.3
Zhang, Y.4
Liu, S.-M.5
Tartaglia, L.6
Leibel, R.L.7
-
21
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
-
Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-159.
-
(1987)
Anal Biochem
, vol.162
, pp. 156-159
-
-
Chomczynski, P.1
Sacchi, N.2
-
22
-
-
0028784923
-
Hypothalamic GH receptor gene expression in the rat: Effects of altered GH status
-
Bennett PA, Levy A, Sophokleous S, Robinson IC, Lightman SL: Hypothalamic GH receptor gene expression in the rat: Effects of altered GH status. J Endocrinol 1995;147:225-234.
-
(1995)
J Endocrinol
, vol.147
, pp. 225-234
-
-
Bennett, P.A.1
Levy, A.2
Sophokleous, S.3
Robinson, I.C.4
Lightman, S.L.5
-
23
-
-
0029895233
-
Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization
-
Mercer JG, Hoggard N, Williams LM, Lawrence CB, Hannah LT, Trayhurn P: Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization. FEBS Lett 1996;387:113-116.
-
(1996)
FEBS Lett
, vol.387
, pp. 113-116
-
-
Mercer, J.G.1
Hoggard, N.2
Williams, L.M.3
Lawrence, C.B.4
Hannah, L.T.5
Trayhurn, P.6
-
24
-
-
0030137757
-
Leptin receptor missense mutation in the fatty Zucker rat
-
Phillips MS, Liu Q, Hammond HA, Dugan V, Hey PJ, Caskey CT, Hess JF: Leptin receptor missense mutation in the fatty Zucker rat. Nat Genet 1996;13:18-19.
-
(1996)
Nat Genet
, vol.13
, pp. 18-19
-
-
Phillips, M.S.1
Liu, Q.2
Hammond, H.A.3
Dugan, V.4
Hey, P.J.5
Caskey, C.T.6
Hess, J.F.7
-
25
-
-
0030570741
-
Molecular cloning of rat leptin receptor isoform complementary DNAs - Identification of a missense mutation in Zucker fatty (fa/fa) rats
-
Takaya K, Ogawa Y, Isse N, Okazaki T, Satoh N, Masuzaki H, Mori K, Tamura N, Hosoda K, Nakao K: Molecular cloning of rat leptin receptor isoform complementary DNAs - Identification of a missense mutation in Zucker fatty (fa/fa) rats. Biochem Biophys Res Commun 1996;225:75-83.
-
(1996)
Biochem Biophys Res Commun
, vol.225
, pp. 75-83
-
-
Takaya, K.1
Ogawa, Y.2
Isse, N.3
Okazaki, T.4
Satoh, N.5
Masuzaki, H.6
Mori, K.7
Tamura, N.8
Hosoda, K.9
Nakao, K.10
-
26
-
-
0030956390
-
The leptin receptor activates janus kinase 2 and signals for proliferation in a factor-dependent cell line
-
Ghilardi N, Skoda RC: The leptin receptor activates janus kinase 2 and signals for proliferation in a factor-dependent cell line. Mol Endocrinol 1997;11:393-399.
-
(1997)
Mol Endocrinol
, vol.11
, pp. 393-399
-
-
Ghilardi, N.1
Skoda, R.C.2
-
27
-
-
0029739970
-
Identification of targets of leptin action in rat hypothalamus
-
Schwartz MW, Seeley RJ, Campfield LA, Burn P, Baskin DG: Identification of targets of leptin action in rat hypothalamus. J Clin Invest 1996;98:1101-1106.
-
(1996)
J Clin Invest
, vol.98
, pp. 1101-1106
-
-
Schwartz, M.W.1
Seeley, R.J.2
Campfield, L.A.3
Burn, P.4
Baskin, D.G.5
-
28
-
-
0029804743
-
Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y
-
Erickson JC, Hollopeter G, Palmiter RD: Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y. Science 1996;274:1704-1707.
-
(1996)
Science
, vol.274
, pp. 1704-1707
-
-
Erickson, J.C.1
Hollopeter, G.2
Palmiter, R.D.3
-
29
-
-
0012095066
-
Olfaction and nutrition
-
Lloyd M Beidler (ed). Berlin, Springer
-
Le Magnen J: Olfaction and nutrition; in Lloyd M Beidler (ed): Handbook of Sensory Physiology. Berlin, Springer, 1971 vol IV, pp 465-482.
-
(1971)
Handbook of Sensory Physiology
, vol.4
, pp. 465-482
-
-
Le Magnen, J.1
-
31
-
-
0029048408
-
Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
-
Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P: Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks. Science 1995;269:546-549.
-
(1995)
Science
, vol.269
, pp. 546-549
-
-
Campfield, L.A.1
Smith, F.J.2
Guisez, Y.3
Devos, R.4
Burn, P.5
-
32
-
-
0021013539
-
Role of ventromedial nucleus of the thalamus in motor behaviour. II. Effects of lesions
-
Starr MS, Summerhayes M: Role of ventromedial nucleus of the thalamus in motor behaviour. II. Effects of lesions. Neuroscience 1983;10:1171-1183.
-
(1983)
Neuroscience
, vol.10
, pp. 1171-1183
-
-
Starr, M.S.1
Summerhayes, M.2
-
33
-
-
0021048246
-
Role of ventromedial nucleus of the thalamus in motor behaviour. I. Effects of focal injections of drugs
-
Starr MS, Summerhayes M: Role of ventromedial nucleus of the thalamus in motor behaviour. I. Effects of focal injections of drugs. Neuroscience 1983;10:1157-1169.
-
(1983)
Neuroscience
, vol.10
, pp. 1157-1169
-
-
Starr, M.S.1
Summerhayes, M.2
-
34
-
-
0030594830
-
Decreased cerebrospinal-fluid/serum leptin ratio in obesity: A possible mechanism for leptin resistance
-
Caro JF, Kolaczynski JW, Nyce MR, Ohannesian JP, Opentanova I, Goldman WH, Lynn RB, Zhang PL, Sinha MK, Considine RV: Decreased cerebrospinal-fluid/serum leptin ratio in obesity: A possible mechanism for leptin resistance. Lancet 1996;348:159-161.
-
(1996)
Lancet
, vol.348
, pp. 159-161
-
-
Caro, J.F.1
Kolaczynski, J.W.2
Nyce, M.R.3
Ohannesian, J.P.4
Opentanova, I.5
Goldman, W.H.6
Lynn, R.B.7
Zhang, P.L.8
Sinha, M.K.9
Considine, R.V.10
-
35
-
-
0029881125
-
Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans
-
Schwartz MW, Peskind E, Raskind M, Boyko EJ, Porte D Jr: Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans. Nat Med 1996;2:589-593.
-
(1996)
Nat Med
, vol.2
, pp. 589-593
-
-
Schwartz, M.W.1
Peskind, E.2
Raskind, M.3
Boyko, E.J.4
Porte Jr., D.5
-
36
-
-
0030807358
-
Diet induced obese mice develop peripheral, but not central, resistance to leptin
-
Van Heek M, Compton DS, France CF, Tedesco RP, Fawzi AB, Graziano MP, Sybertz EJ, Strader CD, Davis HR: Diet induced obese mice develop peripheral, but not central, resistance to leptin. J Clin Invest 1997;99:385-390.
-
(1997)
J Clin Invest
, vol.99
, pp. 385-390
-
-
Van Heek, M.1
Compton, D.S.2
France, C.F.3
Tedesco, R.P.4
Fawzi, A.B.5
Graziano, M.P.6
Sybertz, E.J.7
Strader, C.D.8
Davis, H.R.9
-
37
-
-
0031017561
-
Human blood-brain barrier leptin receptor: Binding and endocytosis in isolated human brain microvessels
-
Golden PL, Maccagnan TJ, Pardridge WM: Human blood-brain barrier leptin receptor: Binding and endocytosis in isolated human brain microvessels. J Clin Invest 1997;99:14-18.
-
(1997)
J Clin Invest
, vol.99
, pp. 14-18
-
-
Golden, P.L.1
Maccagnan, T.J.2
Pardridge, W.M.3
-
38
-
-
33644599665
-
Comparison of the effects of gonadectomy on spontaneous activity of wild and domesticated Norway rats
-
Richter CP, Uhlenhuth EH: Comparison of the effects of gonadectomy on spontaneous activity of wild and domesticated Norway rats. Endocrinology 1954;54:323-337.
-
(1954)
Endocrinology
, vol.54
, pp. 323-337
-
-
Richter, C.P.1
Uhlenhuth, E.H.2
-
39
-
-
0015433994
-
Ovarian-adrenal interactions in regulation of body weight by female rats
-
Mook DG, Kenney NJ, Roberts S, Nussbaum AI, Rodier WI: Ovarian-adrenal interactions in regulation of body weight by female rats. J Comp Physiol Psychol 1972;81:198-211.
-
(1972)
J Comp Physiol Psychol
, vol.81
, pp. 198-211
-
-
Mook, D.G.1
Kenney, N.J.2
Roberts, S.3
Nussbaum, A.I.4
Rodier, W.I.5
-
40
-
-
0031040784
-
Regulation of leptin receptor and NPY gene expression in hypothalamus of leptin treated obese (ob/ob) and cold exposed lean mice
-
Mercer JG, Moar KM, Rayner DV, Trayhurn P, Hoggard N: Regulation of leptin receptor and NPY gene expression in hypothalamus of leptin treated obese (ob/ob) and cold exposed lean mice. FEBS Lett 1997;402:185-188.
-
(1997)
FEBS Lett
, vol.402
, pp. 185-188
-
-
Mercer, J.G.1
Moar, K.M.2
Rayner, D.V.3
Trayhurn, P.4
Hoggard, N.5
-
41
-
-
0021747962
-
Mouse mutants as models in endocrine research
-
Charlton HM: Mouse mutants as models in endocrine research. Q J Exp Physiol 1984;69:655-676.
-
(1984)
Q J Exp Physiol
, vol.69
, pp. 655-676
-
-
Charlton, H.M.1
-
42
-
-
0002548568
-
Phenotypic characterization of a genetically obese and hypertensive rat strain: SHROB/Kol
-
Koletsky RJ, Ernsberger P: Phenotypic characterization of a genetically obese and hypertensive rat strain: SHROB/Kol. Rat Genome 1996;2:10-22.
-
(1996)
Rat Genome
, vol.2
, pp. 10-22
-
-
Koletsky, R.J.1
Ernsberger, P.2
|