Functional anchoring of the cAMP-dependent protein kinase

Trends in Cardiovascular Medicine

Volumn 8, Issue 2, 1998, Pages 89-95

  Murphy, Brian J ^a   Scott, John D ^b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CALCIUM CHANNEL; CYCLIC AMP DEPENDENT PROTEIN KINASE; GLUTAMATE RECEPTOR; POTASSIUM CHANNEL;

CELLULAR DISTRIBUTION; CHANNEL GATING; ENZYME LOCALIZATION; HEART MUSCLE CELL; HUMAN; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REVIEW; SIGNAL TRANSDUCTION;

EID: 0031930322     PISSN: 10501738     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1050-1738(97)00131-X     Document Type: Review

References (63)

1. Adams SR, Harootunian AT, Buechler YJ, Taylor SS, Tsien RY Fluorescence ratio imaging of cyclic AMP in single cells. Nature. 349:1991;694-697.
2. Bregman DB, Bhattacharyya N, Rubin CS High affinity binding protein for the regulatory subunit of cAMP-dependent protein kinase II-B. J Biol Chem. 264:1989;4648-4656.
3. Carr DW, Scott JD Blotting and bandshifting: techniques for studying protein-protein interactions. Trends Biochem Sci. 17:1992;246-249.
4. Carr DW, Stofko-Hahn RE, Fraser ID, et al.: 1991. Interaction of the regulatory subunit (RII) of cAMP-dependent protein kinase with RII-anchoring proteins occurs through an amphipathic helix binding motif. J Biol Chem 266:14,188-14,192.
5. Carr DW, Hausken ZE, Fraser ID, Stofko-Hahn RE, Scott JD: 1992a. Association of the type II cAMP-dependent protein kinase with a human thyroid RII-anchoring protein: cloning and characterization of the RII-binding domain. J Biol Chem 267:13, 376-13,382.
6. Carr DW, Stofko-Hahn RE, Fraser ID, Cone RD, Scott JD: 1992b. Localization of the cAMP-dependent protein kinase to the postsynaptic densities by A-kinase anchoring proteins: characterization of AKAP79. J Biol Chem 267:16,816-16,823.
7. Carr DW, DeManno DA, Atwood A, Hunzicker-Dunn M, Scott JD: 1993. Follicle-stimulating hormone regulation of A-kinase anchoring proteins in granulosa cells. J Biol Chem 268:20,729-20,732.
8. Carrera A, Gerton GL, Moss SB The major fibrous sheath polypeptide of mouse sperm: structural and functional similarities to the A-kinase anchoring proteins. Dev Biol. 165:1994;272-284.
9. Carrera A, Moos J, Ning XPet al. Regulation of protein tyrosine phosphorylation in human sperm by a calcium/calmodulin-dependent mechanism: identification of A kinase anchor proteins as major substrates for tyrosine phosphorylation. Dev Biol. 180:1996;284-296.
10. Catterall WA Excitation-contraction coupling in vertebrate skeletal muscle: a tale of two calcium channels. Cell. 64:1991;871-874.
11. Cheley S, Panchal RG, Carr DW, Scott JD, Bayley H Type II regulatory subunits of cAMP-dependent protein kinase and their binding proteins in the nervous system of Aplysia californica. J Biol Chem. 269:1994;2911-2920.
12. Coghlan VM, Langeberg LK, Fernandez A, Lamb NJ, Scott JD Cloning and characterization of AKAP 95, a nuclear protein that associates with the regulatory subunit of type II cAMP-dependent protein kinase. J Biol Chem. 269:1994;7658-7665.
13. Coghlan VM, Lester L, Scott JD A targeting model for reversible phosphorylation. Adv Prot Phosphatases. 6:1995;51-61.
14. Coghlan VM, Perrino BA, Howard Met al. Association of protein kinase A and protein phosphatase 2B with a common anchoring protein. Science. 267:1995;108-111.
15. Cohen P The structure and regulation of protein phosphatases. Annu Rev Biochem. 58:1989;453-508.
16. Dransfield DT, Bradford AJ, Smith Jet al. Ezrin is a cyclic AMP-dependent protein kinase anchoring protein. EMBO. 16:1997;35-43.
17. Faux MC, Scott JD Molecular glue: kinase anchoring and scaffold proteins. Cell. 85:1996;9-12.
18. Faux MC, Scott JD More on target with protein phosphorylation: conferring specificity by location. Trends Biochem Sci. 21:1996;312-315.
19. Feliciello A, Giuliano P, Porcellini A, et al.: 1996. The v-Ki-Ras oncogene alters cAMP nuclear signaling by regulating the location and the expression of cAMP-dependent protein kinase II beta. J Biol Chem. 271:26,350-25,359.
20. 2+ channels requires membrane targeting of PKA and phosphorylation of channel subunits. Neuron. 19:1997;185-196.
21. Glantz SB, Li Y, Rubin CS: 1993. Characterization of distinct tethering and intracellular targeting domains in AKAP75, a protein that links cAMP-dependent protein kinase II beta to the cytoskeleton. J Biol Chem 268:12,796-12,804.
22. Gray PC, Tibbs VC, Catterall WA, Murphy BJ Identification of a 15-kD cAMP-dependent protein kinase-anchoring protein associated with skeletal muscle L-type calcium channels. J Biol Chem. 272:1997;6297-6302.
23. Greengard P, Jen J, Nairn AC, Stevens CF Enhancement of the glutamate response by cAMP-dependent protein kinase in hippocampal neurons. Science. 253:1991;1135-1138.
24. Harper JF, Haddox MK, Johanson RA, Hanley RM, Steiner AL Compartmentation of second messenger action: immunocytochemical and biochemical evidence. Vitam Horm. 42:1985;197-252.
25. Hempel CM, Vincent P, Adams SR, Tsien RY, Selverston AI Spatio-temporal dynamics of cyclis AMP signals in an intact neural circuitm [see comments]. Nature. 384:1996;166-169.
26. Hirsch AH, Glantz SB, Li Y, You Y, Rubin CS Cloning and expression of an intronless gene for AKAP 75, an anchor protein for the regulatory subunit of cAMP-dependent protein kinase II beta. J Biol Chem. 267:1992;2131-2134.
27. Horowitz JA, Wasco W, Leiser M, Orr GA Interaction of the regulatory subunit of a type II cAMP-dependent protein kinase with mammalian sperm flagellum. J Biol Chem. 263:1988;2098-2104.
28. Huang LJ-S, Durick K, Weiner JA, Chun J, Taylor SS Identification of a novel protein kinase A anchoring protein that binds both type I and type II regulatory subunits. J Biol Chem. 272:1997;8057-8064.
29. Hubbard MJ, Cohen P On target with a new mechanism for the regulation of protein phosphorylation. Trends Biochem Sci. 18(5):1993;172-177.
30. Joachim S, Schwoch G Localization of cAMP-dependent protein kinase subunits along the secretory pathway in pancreatic and parotid acinar cells and accumulation of the catalytic subunit in parotid secretory granules following beta-adrenergic stimulation. Eur J Cell Biol. 51:1990;76-84.
31. 2+ channels in skeletal muscle cells requires anchored cAMP-dependent protein kinase. Proc Natl Acad Sci USA 91:11,492-11,496.
32. Johnson BD, Brousal JP, Peterson BZet al. Modulation of the cloned skeletal muscle L-type Calcium channel by anchored cAMP-dependent protein kinase. J Neurosci. 17:1997;1243-1255.
33. Joly JC, Flynn G, Purich DL The microtubule-binding fragment of microtubule-associated protein-2: location of the protease-accessible site and identification of an assembly-promoting peptide. J Cell Biol. 109:1989;2289-2294.
34. 2+ channels by beta-adrenergic agonists. Proc Natl Acad Sci USA. 93:1996;295-299.
35. Kawano S, Nakamura F, Tanaka T, Hiraoka M Cardiac sarcoplasmic reticulum chloride channels regulated by protein kinase A. Circ Res. 71:1992;585-589.
36. Keryer G, Rios RM, Landmark BF, Skalhegg B, Lohmann SM, Bornens M A high-affinity binding protein for the regulatory subunit of cAMP-dependent protein kinase II in the centrosome of human cells. Exp Cell Res. 204:1993;230-240.
37. Klauck TM, Faux MC, Labudda LK, Langeberg LK, Jaken S, Scott JD Coordination of three signaling enzymes by AKAP79, a mammalian scaffold protein. Science. 271:1996;1589-1592.
38. Krebs EG The phosphorylation of proteins: a major mechanism for biological regulation: fourteenth Sir Frederick Gowland Hopkins memorial lecture. Biochem Soc Trans. 13:1985;813-820.
39. Lester LB, Coghlan VM, Nauert B, Scott JD Cloning and characterization of a novel A-kinase anchoring protein. AKAP 220, association with testicular peroxisomes. J Biol Chem. 271:1996;9460-9465.
40. Li Y, Ndubuka C, Rubin CS: 1996. A kinase anchor protein 75 targets regulatory (RII) subunits of cAMP-dependent protein kinase II to the cortical actin cytoskeleton in non-neuronal cells. J Biol Chem 271:16,862-16,869.
41. Lin RY, Moss SB, Rubin CS: 1995. Characterization of S-AKAP84, a novel developmentally regulated A kinase anchor protein of male germ cells. J Biol Chem 270:27,804-27,811.
42. Livesey SA, Kemp BE, Re CA, Partridge NC, Martin TJ: 1982. Selective hormonal activation of cyclic AMP-dependent protein kinase isoenzymes in normal and malignant osteoblasts. J Biol Chem 257:14,983-14,987.
43. Lohmann SM, DeCamilli P, Einig I, Walter U High-affinity binding of the regulatory subunit (RII) of cAMP-dependent protein kinase to microtubule-associated and other cellular proteins. Proc Natl Acad Sci USA. 81:1984;6723-6727.
44. Luo Z, Shafit Zagardo B, Erlichman J: 1990. Identification of the MAP2- and P75-binding domain in the regulatory subunit (RII beta) of type II cAMP-dependent protein kinase: cloning and expression of the cDNA for bovine brain RII beta. J Biol Chem 265:21,804-21,810.
45. McCartney S, Little BM, Langeberg LK, Scott JD Cloning and characterization of A-kinase anchor protein 100 (AKAP100): a protein that targets A-kinase to the sarcoplasmic reticulum. J Biol Chem. 270:1995;9327-9333.
46. Murphy BJ, Tuana BS Phosphorylation and the identification of a protein kinase activity associated with the dihydropyridine receptor isolated from rabbit heart and skeletal muscle. Ann Rev NY Acad Sci. 560:1989;391-394.
47. Nauert JB, Klauck TM, Langeberg LK, Scott JD Gravin, an autoantigen recognized by serum from myasthenia gravis patients, is a kinase scaffold protein. Curr Biol. 7:1997;52-62.
48. Obar RA, Dingus J, Bayley H, Vallee RB The RII subunit of cAMP-dependent protein kinase binds to a common amino-terminal domain in microtubule-associated proteins 2A, 2B, and 2C. Neuron. 3:1989;639-645.
49. Pariset C, Weinman S Differential localization of two isoforms of the regulatory subunit RII alpha of cAMP-dependent protein kinase in human sperm: biochemical and cytochemical study. Mol Reprod Dev. 39:1994;415-422.
50. Rios RM, Celati C, Lohmann SM, Bornens M, Keryer G Identification of a high affinity binding protein for the regulatory subunit RII beta of cAMP-dependent protein kinase in Golgi enriched membranes of human lymphoblasts. EMBO J. 11:1992;1723-1731.
51. Rosenmund C, Carr DW, Bergeson SE, Nilaver G, Scott JD, Westbrook GL Anchoring of protein kinase A is required for modulation of AMPA/kainate receptors on hippocampal neurons. Nature. 368:1994;853-856.
52. Rubin CS, Rangel Aldao R, Sarkar D, Erlichman J, Fleischer N Characterization and comparison of membrane-associated and cytosolic cAMP-dependent protein kinases: physicochemical and immunological studies on bovine cerebral cortex protein kinases. J Biol Chem. 254:1979;3797-3805.
53. Rubino HM, Dammerman M, Shafit-Zagardo B, Erlichman J Localization and characterization of the binding site for the regulatory subunit of type II cAMP-dependent protein kinase on MAP2. Neuron. 3:1989;631-638.
54. Salvatori S, Damiani E, Barhanin J, Furlan S, Salviati G, Margreth A Co-localization of the dihydropyridine receptor and the cyclic AMP-binding subunit of an intrinsic protein kinase to the junctional membrane of the transverse tubules of skeletal muscle. Biochem J. 267:1990;679-687.
55. Sarkar D, Erlichman J, Rubin CS Identification of a calmodulin-binding protein that co-purifies with the regulatory subunit of brain protein kinase II. J Biol Chem. 259:1984;9840-9846.
56. Scott JD, Stofko RE, McDonald JR, Comer JD, Vitalis EA, Mangili JA: 1990. Type II regulatory subunit dimerization determines the subcellular localization of the cAMP-dependent protein kinase. J Biol Chem 265:21,561-21,566.
57. Sculptoreanu A, Rotman E, Takahashi M, Scheuer T, Catterall WA: 1993a. Voltage-dependent potentiation of the activity of cardiac L-type calcium channel alpha 1 subunits due to phosphorylation by cAMP-dependent protein kinase. Proc Natl Acad Sci USA 90:10,135-10,139.
58. 2+ channels due to phosphorylation by cAMP-dependent protein kinase. Nature. 364:1993;240-243.
59. Taylor SS cAMP-dependent protein kinase: model for an enzyme family. J Biol Chem. 264:1989;8443-8446.
60. Trendelenburg G, Hummel M, Riecken EO, Hanski C Molecular characterization of AKAP149, a novel A kinase anchor protein with a KH domain. Biochem Biophys Res Commun. 225:1996;313-319.
61. Vijayaraghavan S, Goueli SA, Davey MP, Carr DW PKA anchoring inhibitor peptides arrest mammalian sperm motility. J Biol Chem. 272:1997;4747-4752.
62. Wang LY, Salter MW, MacDonald JF Regulation of kainate receptors by cAMP-dependent protein kinase and phosphatases. Science. 253:1991;1132-1135.
63. Wang ZW, Kotlikoff MI: 1996. Activation of KCa channels in airway smooth muscle cells by endogenous protein kinase A. Am J Physiol 271:L100-105.