메뉴 건너뛰기




Volumn 95, Issue 6, 2000, Pages 2068-2075

Inducible loss of NF-κB activity is associated with apoptosis and Bcl-2 down-regulation in Epstein-Barr virus-transformed B lymphocytes

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN BCL 2; TRANSCRIPTION FACTOR;

EID: 0034653552     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v95.6.2068.2068     Document Type: Article
Times cited : (82)

References (73)
  • 1
    • 0031126817 scopus 로고    scopus 로고
    • The role of Rel/NF-kappa B proteins in viral oncogenesis and the regulation of viral transcription
    • Mosialos G. The role of Rel/NF-kappa B proteins in viral oncogenesis and the regulation of viral transcription. Semin Cancer Biol. 1997;8:121.
    • (1997) Semin Cancer Biol , vol.8 , pp. 121
    • Mosialos, G.1
  • 3
    • 0027232067 scopus 로고
    • NF-kappa B and Rel: Participants in a multiform transcriptional regulatory system
    • Grilli M, Chiu JJ, Lenardo MJ. NF-kappa B and Rel: participants in a multiform transcriptional regulatory system. Int Rev Cytol. 1993;143:1.
    • (1993) Int Rev Cytol , vol.143 , pp. 1
    • Grilli, M.1    Chiu, J.J.2    Lenardo, M.J.3
  • 4
    • 0031126395 scopus 로고    scopus 로고
    • I kappa B proteins: Structure, function and regulation
    • Whiteside ST, Israel A. I kappa B proteins: structure, function and regulation. Semin Cancer Biol. 1997;8:75.
    • (1997) Semin Cancer Biol , vol.8 , pp. 75
    • Whiteside, S.T.1    Israel, A.2
  • 5
    • 0030610362 scopus 로고    scopus 로고
    • A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB
    • DiDonato JA, Hayakawa M, Rothwarf DM, Zandi E, Karin M. A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB. Nature. 1997;388:548.
    • (1997) Nature , vol.388 , pp. 548
    • DiDonato, J.A.1    Hayakawa, M.2    Rothwarf, D.M.3    Zandi, E.4    Karin, M.5
  • 6
    • 0030611595 scopus 로고    scopus 로고
    • IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK
    • Woronicz JD, Gao X, Cao Z, Rothe M, Goeddel DV. IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK. Science. 1997;278:866.
    • (1997) Science , vol.278 , pp. 866
    • Woronicz, J.D.1    Gao, X.2    Cao, Z.3    Rothe, M.4    Goeddel, D.V.5
  • 7
    • 0030685825 scopus 로고    scopus 로고
    • IKK-1 and IKK-2: Cytokine-activated IkappaB kinases essential for NF-kappaB activation
    • Mercurio F, Zhu H, Murray BW, et al. IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation. Science. 1997;278: 860.
    • (1997) Science , vol.278 , pp. 860
    • Mercurio, F.1    Zhu, H.2    Murray, B.W.3
  • 8
    • 0030613551 scopus 로고    scopus 로고
    • The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation
    • Zandi E, Rothwarf DM, Delhase M, Hayakawa M, Karin M. The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation. Cell. 1997;91:243.
    • (1997) Cell , vol.91 , pp. 243
    • Zandi, E.1    Rothwarf, D.M.2    Delhase, M.3    Hayakawa, M.4    Karin, M.5
  • 9
    • 0032568792 scopus 로고    scopus 로고
    • Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation
    • Yamaoka S, Courtois G, Bessia C, et al. Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation. Cell. 1998;93:1231.
    • (1998) Cell , vol.93 , pp. 1231
    • Yamaoka, S.1    Courtois, G.2    Bessia, C.3
  • 10
    • 0029670843 scopus 로고    scopus 로고
    • Constitutive activation of NF-kappa B is essential for transformation of rat fibroblasts by the human T-cell leukemia virus type I Tax protein
    • Yamaoka S, Inoue H, Sakurai M, et al. Constitutive activation of NF-kappa B is essential for transformation of rat fibroblasts by the human T-cell leukemia virus type I Tax protein. EMBO J. 1996;15:873.
    • (1996) EMBO J , vol.15 , pp. 873
    • Yamaoka, S.1    Inoue, H.2    Sakurai, M.3
  • 11
    • 0022445387 scopus 로고
    • Localization of the v-rel protein in reticuloendotheliosis virus strain T-transformed lymphoid cells
    • Simek SL, Stephens RM, Rice NR. Localization of the v-rel protein in reticuloendotheliosis virus strain T-transformed lymphoid cells. J Virol. 1986; 59:120.
    • (1986) J Virol , vol.59 , pp. 120
    • Simek, S.L.1    Stephens, R.M.2    Rice, N.R.3
  • 13
    • 0029994434 scopus 로고    scopus 로고
    • The v-rel oncogene promotes malignant T-cell leukemia/lymphoma in transgenic mice
    • Carrasco D, Rizzo CA, Dorfman K, Bravo R. The v-rel oncogene promotes malignant T-cell leukemia/lymphoma in transgenic mice. EMBO J. 1996;15:3640.
    • (1996) EMBO J , vol.15 , pp. 3640
    • Carrasco, D.1    Rizzo, C.A.2    Dorfman, K.3    Bravo, R.4
  • 14
    • 0026331456 scopus 로고
    • B cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-kappa B p50
    • Neri A, Chang CC, Lombardi L, et al. B cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-kappa B p50. Cell. 1991;67:1075.
    • (1991) Cell , vol.67 , pp. 1075
    • Neri, A.1    Chang, C.C.2    Lombardi, L.3
  • 15
    • 0028033909 scopus 로고
    • Heterogeneous chromosomal aberrations generate 3′ truncations of the NFKB2/lyt-10 gene in lymphoid malignancies
    • Migliazza A, Lombardi L, Rocchi M, et al. Heterogeneous chromosomal aberrations generate 3′ truncations of the NFKB2/lyt-10 gene in lymphoid malignancies. Blood. 1994;84:3850.
    • (1994) Blood , vol.84 , pp. 3850
    • Migliazza, A.1    Lombardi, L.2    Rocchi, M.3
  • 17
    • 0030052683 scopus 로고    scopus 로고
    • REL proto-oncogene is frequently amplified in extranodal diffuse large cell lymphoma
    • Houldsworth J, Mathew S, Rao PH, et al. REL proto-oncogene is frequently amplified in extranodal diffuse large cell lymphoma. Blood. 1996; 87:25.
    • (1996) Blood , vol.87 , pp. 25
    • Houldsworth, J.1    Mathew, S.2    Rao, P.H.3
  • 18
    • 0026465540 scopus 로고
    • The Epstein-Barr virus LMP1 gene product induces A20 zinc finger protein expression by activating nuclear factor kappa B
    • Laherty CD, Hu HM, Opipari AW, Wang F, Dixit VM. The Epstein-Barr virus LMP1 gene product induces A20 zinc finger protein expression by activating nuclear factor kappa B. J Biol Chem. 1992;267:24, 157.
    • (1992) J Biol Chem , vol.267 , pp. 24
    • Laherty, C.D.1    Hu, H.M.2    Opipari, A.W.3    Wang, F.4    Dixit, V.M.5
  • 19
    • 0028853402 scopus 로고
    • The Epstein-Barr virus latent membrane protein-1 (LMP1) mediates activation of NF-kappa B and cell surface phenotype via two effector regions in its carboxy-terminal cytoplasmic domain
    • Huen DS, Henderson SA, Croom-Carier D, Rowe M. The Epstein-Barr virus latent membrane protein-1 (LMP1) mediates activation of NF-kappa B and cell surface phenotype via two effector regions in its carboxy-terminal cytoplasmic domain. Oncogene. 1995;10:549.
    • (1995) Oncogene , vol.10 , pp. 549
    • Huen, D.S.1    Henderson, S.A.2    Croom-Carier, D.3    Rowe, M.4
  • 20
    • 0028987479 scopus 로고
    • Stimulation of NF-kappa B-mediated transcription by mutant derivatives of the latent membrane protein of Epstein-Barr virus
    • Milchell T, Sugden B. Stimulation of NF-kappa B-mediated transcription by mutant derivatives of the latent membrane protein of Epstein-Barr virus. J Virol. 1995;69:2968.
    • (1995) J Virol , vol.69 , pp. 2968
    • Milchell, T.1    Sugden, B.2
  • 21
    • 0030728946 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein-1 triggers AP-1 activity via the c-Jun N-terminal kinase cascade
    • Kieser A, Kilger E, Gires O, Ueffing M, Kolch W, Hammerschmidt W. Epstein-Barr virus latent membrane protein-1 triggers AP-1 activity via the c-Jun N-terminal kinase cascade. EMBO J 1997; 16:6478.
    • (1997) EMBO J , vol.16 , pp. 6478
    • Kieser, A.1    Kilger, E.2    Gires, O.3    Ueffing, M.4    Kolch, W.5    Hammerschmidt, W.6
  • 22
    • 0030716307 scopus 로고    scopus 로고
    • Latent membrane protein 1 of Epstein-Barr virus mimics a constitutively active receptor molecule
    • Gires O, Zimber-Strobl U, Gonnella R, et al. Latent membrane protein 1 of Epstein-Barr virus mimics a constitutively active receptor molecule. EMBO J. 1997;16:6131.
    • (1997) EMBO J , vol.16 , pp. 6131
    • Gires, O.1    Zimber-Strobl, U.2    Gonnella, R.3
  • 23
    • 0031939402 scopus 로고    scopus 로고
    • A fusion of the EBV latent membrane protein-1 (LMP1) transmembrane domains to the CD40 cytoplasmic domain is similar to LMP1 in constitutive activation of epidermal growth factor receptor expression, nuclear factor-kappa B, and stress-activated protein kinase
    • Hatzivassiliou E, Miller WE, Raab-Traub N, Kieff E, Mosialos G. A fusion of the EBV latent membrane protein-1 (LMP1) transmembrane domains to the CD40 cytoplasmic domain is similar to LMP1 in constitutive activation of epidermal growth factor receptor expression, nuclear factor-kappa B, and stress-activated protein kinase. J Immunol. 1998;160:1116.
    • (1998) J Immunol , vol.160 , pp. 1116
    • Hatzivassiliou, E.1    Miller, W.E.2    Raab-Traub, N.3    Kieff, E.4    Mosialos, G.5
  • 24
    • 0029956392 scopus 로고    scopus 로고
    • Association of TRAF1, TRAF2, and TRAF3 with an Epstein-Barr virus LMP1 domain important for B-lymphocyte transformation: Role in NF-kappaB activation
    • Devergne O, Hatzivassiliou E, Izumi KM, et al. Association of TRAF1, TRAF2, and TRAF3 with an Epstein-Barr virus LMP1 domain important for B-lymphocyte transformation: role in NF-kappaB activation. Mol Cell Biol. 1996;16:7098.
    • (1996) Mol Cell Biol , vol.16 , pp. 7098
    • Devergne, O.1    Hatzivassiliou, E.2    Izumi, K.M.3
  • 25
    • 0030815756 scopus 로고    scopus 로고
    • The Epstein-Barr virus oncogene product latent membrane protein 1 engages the tumor necrosis factor receptor-associated death domain protein to mediate B lymphocyte growth transformation and activate NF-kappaB
    • Izumi KM, Kieff ED. The Epstein-Barr virus oncogene product latent membrane protein 1 engages the tumor necrosis factor receptor-associated death domain protein to mediate B lymphocyte growth transformation and activate NF-kappaB. Proc Natl Acad Sci U S A. 1997;94:12,592.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 12592
    • Izumi, K.M.1    Kieff, E.D.2
  • 26
    • 0032544010 scopus 로고    scopus 로고
    • Epstein-Barr virus-transforming protein latent infection membrane protein 1 activates transcription factor NF-kappaB through a pathway that includes the NF-kappaB-inducing kinase and the IkappaB kinases IKKalpha and IKKbeta
    • Sylla BS, Hung SC, Davidson DM, et al. Epstein-Barr virus-transforming protein latent infection membrane protein 1 activates transcription factor NF-kappaB through a pathway that includes the NF-kappaB-inducing kinase and the IkappaB kinases IKKalpha and IKKbeta. Proc Natl Acad Sci U S A. 1998;95:10,106.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 10106
    • Sylla, B.S.1    Hung, S.C.2    Davidson, D.M.3
  • 27
    • 0028978032 scopus 로고
    • Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli
    • Traenckner EB, Pahl HL, Henkel T, Schmidt KN, Wilk S, Baeuerle PA. Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli. EMBO J. 1995;14:2876.
    • (1995) EMBO J , vol.14 , pp. 2876
    • Traenckner, E.B.1    Pahl, H.L.2    Henkel, T.3    Schmidt, K.N.4    Wilk, S.5    Baeuerle, P.A.6
  • 29
    • 0021993827 scopus 로고
    • A vector that replicates as a plasmid and can be efficiently selected in B-lymphoblasts transformed by Epstein-Barr virus
    • Sugden B, Marsh K, Yates J. A vector that replicates as a plasmid and can be efficiently selected in B-lymphoblasts transformed by Epstein-Barr virus. Mol Cell Biol. 1985;5:410.
    • (1985) Mol Cell Biol , vol.5 , pp. 410
    • Sugden, B.1    Marsh, K.2    Yates, J.3
  • 30
    • 0021988550 scopus 로고
    • Stable replication of plasmids derived from Epstein-Barr virus in various mammalian cells
    • Yates JL, Warren N, Sugden B. Stable replication of plasmids derived from Epstein-Barr virus in various mammalian cells. Nature. 1985;313:812.
    • (1985) Nature , vol.313 , pp. 812
    • Yates, J.L.1    Warren, N.2    Sugden, B.3
  • 31
    • 0026720075 scopus 로고
    • Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
    • Gossen M, Bujard H. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci U S A. 1992;89:5547.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 5547
    • Gossen, M.1    Bujard, H.2
  • 32
    • 0027453548 scopus 로고
    • Promoter analysis of the gene encoding the I kappa B-alpha/MAD3 inhibitor of NF-kappa B: Positive regulation by members of the rel/NF-kappa B family
    • Le Bail O, Schmidt-Ullrich R, Israel A. Promoter analysis of the gene encoding the I kappa B-alpha/MAD3 inhibitor of NF-kappa B: positive regulation by members of the rel/NF-kappa B family. EMBO J. 1993;12:5043.
    • (1993) EMBO J , vol.12 , pp. 5043
    • Le Bail, O.1    Schmidt-Ullrich, R.2    Israel, A.3
  • 33
    • 0026161587 scopus 로고
    • NF-kappa B activation by tumor necrosis factor alpha in the Jurkat T cell line is independent of protein kinase A, protein kinase C, and Ca(2+)-regulated kinases
    • Feuillard J, Gouy H, Bismuth G, Lee LM, Debre P, Korner M. NF-kappa B activation by tumor necrosis factor alpha in the Jurkat T cell line is independent of protein kinase A, protein kinase C, and Ca(2+)-regulated kinases. Cytokine. 1991;3:257.
    • (1991) Cytokine , vol.3 , pp. 257
    • Feuillard, J.1    Gouy, H.2    Bismuth, G.3    Lee, L.M.4    Debre, P.5    Korner, M.6
  • 34
    • 0031569096 scopus 로고    scopus 로고
    • Nuclear Rel-A and c-Rel protein complexes are differentially distributed within human thymocytes
    • Feuillard J, Dargemont C, Ferreira V, et al. Nuclear Rel-A and c-Rel protein complexes are differentially distributed within human thymocytes. J Immunol. 1997;158:2585.
    • (1997) J Immunol , vol.158 , pp. 2585
    • Feuillard, J.1    Dargemont, C.2    Ferreira, V.3
  • 35
    • 0023874501 scopus 로고
    • Alterations in binding characteristics of the human immunodeficiency virus enhancer factor
    • Wu F, Garcia J, Mitsuyasu R, Gaynor R. Alterations in binding characteristics of the human immunodeficiency virus enhancer factor. J Virol. 1988;62:218.
    • (1988) J Virol , vol.62 , pp. 218
    • Wu, F.1    Garcia, J.2    Mitsuyasu, R.3    Gaynor, R.4
  • 36
    • 0017342054 scopus 로고
    • Improved resolution of myofibrillar proteins with sodium dodecyl sulfate -polyacrylamide gel electrophoresis
    • Porzio MA, Pearson AM. Improved resolution of myofibrillar proteins with sodium dodecyl sulfate -polyacrylamide gel electrophoresis. Biochim Biophys Acta. 1977;490:27.
    • (1977) Biochim Biophys Acta , vol.490 , pp. 27
    • Porzio, M.A.1    Pearson, A.M.2
  • 37
    • 0038312438 scopus 로고
    • Electrophoresis
    • Ed TC, ed. New York: John Wiley & Sons
    • Cooper T. Electrophoresis. In Ed TC, ed. The Tools of Biochemistry. New York: John Wiley & Sons; 1977:194.
    • (1977) The Tools of Biochemistry , pp. 194
    • Cooper, T.1
  • 38
    • 0028986046 scopus 로고
    • Domain organization of I kappa B alpha and sites of interaction with NF-kappa B p65
    • Jaffray E, Wood KM, Hay RT. Domain organization of I kappa B alpha and sites of interaction with NF-kappa B p65. Mol Cell Biol. 1995; 15:2166.
    • (1995) Mol Cell Biol , vol.15 , pp. 2166
    • Jaffray, E.1    Wood, K.M.2    Hay, R.T.3
  • 39
    • 0027451668 scopus 로고
    • p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
    • Lowe SW, Ruley HE, Jacks T, Housman DE. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell. 1993;74:957.
    • (1993) Cell , vol.74 , pp. 957
    • Lowe, S.W.1    Ruley, H.E.2    Jacks, T.3    Housman, D.E.4
  • 40
    • 0029976817 scopus 로고    scopus 로고
    • An essential role for NF-kappaB in preventing TNF-alpha-induced cell death
    • Beg AA, Baltimore D. An essential role for NF-kappaB in preventing TNF-alpha-induced cell death. Science. 1996;274:782.
    • (1996) Science , vol.274 , pp. 782
    • Beg, A.A.1    Baltimore, D.2
  • 41
    • 0029858387 scopus 로고    scopus 로고
    • TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-kappaB
    • Wang CY, Mayo MW, Baldwin AS Jr. TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB. Science. 1996;274: 784.
    • (1996) Science , vol.274 , pp. 784
    • Wang, C.Y.1    Mayo, M.W.2    Baldwin A.S., Jr.3
  • 43
    • 0025772343 scopus 로고
    • Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death
    • Henderson S, Rowe M, Gregory C, et al. Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death. Cell. 1991;65:1107.
    • (1991) Cell , vol.65 , pp. 1107
    • Henderson, S.1    Rowe, M.2    Gregory, C.3
  • 44
    • 0027939679 scopus 로고
    • Upregulation of bcl-2 by the Epstein-Barr virus latent membrane protein LMP1: A B-cell-specific response that is delayed relative to NF-kappa B activation and to induction of cell surface markers
    • Rowe M, Peng-Pilon M, Huen DS, et al. Upregulation of bcl-2 by the Epstein-Barr virus latent membrane protein LMP1: a B-cell-specific response that is delayed relative to NF-kappa B activation and to induction of cell surface markers. J Virol. 1994;68:5602.
    • (1994) J Virol , vol.68 , pp. 5602
    • Rowe, M.1    Peng-Pilon, M.2    Huen, D.S.3
  • 45
    • 0028878977 scopus 로고
    • The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family
    • Mosialos G, Birkenbach M, Yalamanchili R, VanArsdale T, Ware C, Kieff E. The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family. Cell. 1995;80:389.
    • (1995) Cell , vol.80 , pp. 389
    • Mosialos, G.1    Birkenbach, M.2    Yalamanchili, R.3    VanArsdale, T.4    Ware, C.5    Kieff, E.6
  • 46
    • 0032484473 scopus 로고    scopus 로고
    • Activation of a ras-MAPK-dependent pathway by Epstein-Barr virus latent membrane protein 1 is essential for cellular transformation
    • Roberts ML, Cooper NR. Activation of a ras-MAPK-dependent pathway by Epstein-Barr virus latent membrane protein 1 is essential for cellular transformation. Virology. 1998;240:93.
    • (1998) Virology , vol.240 , pp. 93
    • Roberts, M.L.1    Cooper, N.R.2
  • 47
    • 0023789310 scopus 로고
    • A movable and regulable inactivation function within the steroid binding domain of the glucocorticoid receptor
    • Picard D, Salser SJ, Yamamoto KR. A movable and regulable inactivation function within the steroid binding domain of the glucocorticoid receptor. Cell. 1988;54:1073.
    • (1988) Cell , vol.54 , pp. 1073
    • Picard, D.1    Salser, S.J.2    Yamamoto, K.R.3
  • 48
    • 0024396222 scopus 로고
    • Chimaeras of myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells
    • Eilers M, Picard D, Yamamoto KR, Bishop JM. Chimaeras of myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells. Nature. 1989;340:66.
    • (1989) Nature , vol.340 , pp. 66
    • Eilers, M.1    Picard, D.2    Yamamoto, K.R.3    Bishop, J.M.4
  • 49
    • 0028890144 scopus 로고
    • B-cell proliferation and induction of early G1-regulating proteins by Epstein-Barr virus mutants conditional for EBNA2
    • Kempkes B, Spitkovsky D, Jansen-Durr P, et al. B-cell proliferation and induction of early G1-regulating proteins by Epstein-Barr virus mutants conditional for EBNA2. EMBO J. 1995;14:88.
    • (1995) EMBO J , vol.14 , pp. 88
    • Kempkes, B.1    Spitkovsky, D.2    Jansen-Durr, P.3
  • 50
    • 0028831128 scopus 로고
    • Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors
    • Scheinman RI, Gualberto A, Jewell CM, Cidlowski JA, Baldwin AS Jr. Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors. Mol Cell Biol. 1995;15:943.
    • (1995) Mol Cell Biol , vol.15 , pp. 943
    • Scheinman, R.I.1    Gualberto, A.2    Jewell, C.M.3    Cidlowski, J.A.4    Baldwin A.S., Jr.5
  • 51
    • 0016441839 scopus 로고
    • Glucocorticoid receptors in mouse mammary tumors: Specific binding to nuclear components
    • Shyamala G. Glucocorticoid receptors in mouse mammary tumors: specific binding to nuclear components. Biochemistry. 1975;14:437.
    • (1975) Biochemistry , vol.14 , pp. 437
    • Shyamala, G.1
  • 52
    • 0027501690 scopus 로고
    • Control of gene activity in higher eukaryotic cells by prokaryotic regulatory elements
    • Gossen M, Bonin AL, Bujard H. Control of gene activity in higher eukaryotic cells by prokaryotic regulatory elements. Trends Biochem Sci. 1993; 18:471.
    • (1993) Trends Biochem Sci , vol.18 , pp. 471
    • Gossen, M.1    Bonin, A.L.2    Bujard, H.3
  • 53
    • 0028173667 scopus 로고
    • Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system
    • Resnitzky D, Gossen M, Bujard H, Reed SI. Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system. Mol Cell Biol. 1994;14:1669.
    • (1994) Mol Cell Biol , vol.14 , pp. 1669
    • Resnitzky, D.1    Gossen, M.2    Bujard, H.3    Reed, S.I.4
  • 54
    • 0027202760 scopus 로고
    • Regulatory elements in the immunoglobulin kappa locus induce c-myc activation and the promoter shift in Burkitt's lymphoma cells
    • Polack A, Feederte R, Klobeck G, Hortnagel K. Regulatory elements in the immunoglobulin kappa locus induce c-myc activation and the promoter shift in Burkitt's lymphoma cells. EMBO J. 1993;12:3913.
    • (1993) EMBO J , vol.12 , pp. 3913
    • Polack, A.1    Feederte, R.2    Klobeck, G.3    Hortnagel, K.4
  • 55
    • 0029814787 scopus 로고    scopus 로고
    • c-myc activation renders proliferation of Epstein-Barr virus (Ebv)-transformed cells independent of Ebv nuclear antigen 2 and latent membrane protein 1
    • Polack A, Hortnagel K, Pajic A. et al. c-myc activation renders proliferation of Epstein-Barr virus (Ebv)-transformed cells independent of Ebv nuclear antigen 2 and latent membrane protein 1. Proc Natl Acad Sci U S A. 1996;93:10,411.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 10411
    • Polack, A.1    Hortnagel, K.2    Pajic, A.3
  • 56
    • 0028959967 scopus 로고
    • Immortalization of human B lymphocytes by a plasmid containing 71 kilobase pairs of Epstein-Barr virus DNA
    • Kempkes B, Pich D, Zeidler R, Sugden B, Hammerschmidt W. Immortalization of human B lymphocytes by a plasmid containing 71 kilobase pairs of Epstein-Barr virus DNA. J Virol. 1995;69: 231.
    • (1995) J Virol , vol.69 , pp. 231
    • Kempkes, B.1    Pich, D.2    Zeidler, R.3    Sugden, B.4    Hammerschmidt, W.5
  • 57
    • 0032536860 scopus 로고    scopus 로고
    • Epstein-Barr virus-mediated B-cell proliferation is dependent upon latent membrane protein 1, which simulates an activated CD40 receptor
    • Kilger E, Kieser A, Baumann M, Hammerschmidt W. Epstein-Barr virus-mediated B-cell proliferation is dependent upon latent membrane protein 1, which simulates an activated CD40 receptor. EMBO J. 1998;17:1700.
    • (1998) EMBO J , vol.17 , pp. 1700
    • Kilger, E.1    Kieser, A.2    Baumann, M.3    Hammerschmidt, W.4
  • 58
    • 16044365828 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of I kappa B-alpha activates NF-kappa B without proteolytic degradation of I kappa B-alpha
    • Imbert V, Rupec RA, Livolsi A, et al. Tyrosine phosphorylation of I kappa B-alpha activates NF-kappa B without proteolytic degradation of I kappa B-alpha. Cell. 1996;86:787.
    • (1996) Cell , vol.86 , pp. 787
    • Imbert, V.1    Rupec, R.A.2    Livolsi, A.3
  • 59
    • 0029665597 scopus 로고    scopus 로고
    • Constitutive phosphorylation of IkappaBalpha by casein kinase II occurs preferentially at serine 293: Requirement for degradation of free IkappaBalpha
    • Schwarz EM, Van Antwerp D, Verma IM. Constitutive phosphorylation of IkappaBalpha by casein kinase II occurs preferentially at serine 293: requirement for degradation of free IkappaBalpha. Mol Cell Biol. 1996;16:3554.
    • (1996) Mol Cell Biol , vol.16 , pp. 3554
    • Schwarz, E.M.1    Van Antwerp, D.2    Verma, I.M.3
  • 60
    • 0032588170 scopus 로고    scopus 로고
    • NF-kappaB function in growth control: Regulation of cyclin D1 expression and G0/G1-to-S-phase transition
    • Hinz M, Krappmann D, Eichten A, Heder A, Scheidereit C, Strauss M. NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transition. Mol Cell Biol. 1999;19:2690.
    • (1999) Mol Cell Biol , vol.19 , pp. 2690
    • Hinz, M.1    Krappmann, D.2    Eichten, A.3    Heder, A.4    Scheidereit, C.5    Strauss, M.6
  • 61
    • 0030823424 scopus 로고    scopus 로고
    • Epstein-Barr virus binding to CD21 activates the initial viral promoter via NF-kappaB induction
    • Sugano N, Chen W, Roberts ML, Cooper NR. Epstein-Barr virus binding to CD21 activates the initial viral promoter via NF-kappaB induction. J Exp Med. 1997;186:731.
    • (1997) J Exp Med , vol.186 , pp. 731
    • Sugano, N.1    Chen, W.2    Roberts, M.L.3    Cooper, N.R.4
  • 62
    • 0032508414 scopus 로고    scopus 로고
    • NF-kappaB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
    • Wang CY, Mayo MW, Korneluk RG, Goeddel DV, Baldwin AS Jr. NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and C-IAP1 and C-IAP2 to suppress caspase-8 activation. Science. 1998; 281:1680.
    • (1998) Science , vol.281 , pp. 1680
    • Wang, C.Y.1    Mayo, M.W.2    Korneluk, R.G.3    Goeddel, D.V.4    Baldwin A.S., Jr.5
  • 63
    • 0031810458 scopus 로고    scopus 로고
    • Inhibition of nuclear factor kappaB activation attenuates apoptosis resistance in lymphoid cells
    • Jeremias I, Kupatt C, Baumann B, Herr I, Wirth T, Debatin KM. Inhibition of nuclear factor kappaB activation attenuates apoptosis resistance in lymphoid cells. Blood. 1998;91:4624.
    • (1998) Blood , vol.91 , pp. 4624
    • Jeremias, I.1    Kupatt, C.2    Baumann, B.3    Herr, I.4    Wirth, T.5    Debatin, K.M.6
  • 64
    • 0029814063 scopus 로고    scopus 로고
    • Inhibition of NF-kappaB/Rel induces apoptosis of murine B cells
    • Wu M, Lee H, Bellas RE, et al. Inhibition of NF-kappaB/Rel induces apoptosis of murine B cells. EMBO J. 1996;15:4682.
    • (1996) EMBO J , vol.15 , pp. 4682
    • Wu, M.1    Lee, H.2    Bellas, R.E.3
  • 65
    • 0032563764 scopus 로고    scopus 로고
    • Relationship between IkappaBalpha constitutive expression, TNFalpha synthesis, and apoptosis in EBV-infected lymphoblastoid cells
    • Asso-Bonnet M, Feuillard J, Ferreira V, et al. Relationship between IkappaBalpha constitutive expression, TNFalpha synthesis, and apoptosis in EBV-infected lymphoblastoid cells. Oncogene. 1998;17:1607.
    • (1998) Oncogene , vol.17 , pp. 1607
    • Asso-Bonnet, M.1    Feuillard, J.2    Ferreira, V.3
  • 66
    • 0029072577 scopus 로고
    • High expression of latent membrane protein 1 of Epstein-Barr virus and BCL-2 oncoprotein in acquired immunodeficiency syndrome-related primary brain lymphomas
    • Camilleri-Broet S, Davi F, Feuillard J, et al. High expression of latent membrane protein 1 of Epstein-Barr virus and BCL-2 oncoprotein in acquired immunodeficiency syndrome-related primary brain lymphomas. Blood. 1995;86:432.
    • (1995) Blood , vol.86 , pp. 432
    • Camilleri-Broet, S.1    Davi, F.2    Feuillard, J.3
  • 67
    • 0032170456 scopus 로고    scopus 로고
    • Anti-sense to the epstein-barr virus (EBV)-encoded latent membrane protein 1 (LMP-1) suppresses LMP-1 and bcl-2 expression and promotes apoptosis in EBV-immortalized b cells
    • Kenney JL, Guinness ME, Curiel T, Lacy J. Anti-sense to the epstein-barr virus (EBV)-encoded latent membrane protein 1 (LMP-1) suppresses LMP-1 and bcl-2 expression and promotes apoptosis in EBV-immortalized B cells. Blood. 1996; 92:1721.
    • (1996) Blood , vol.92 , pp. 1721
    • Kenney, J.L.1    Guinness, M.E.2    Curiel, T.3    Lacy, J.4
  • 68
    • 0033593572 scopus 로고    scopus 로고
    • Cell death in development
    • Vaux D, Korsmeyer S. Cell death in development. Cell. 1999;96:245.
    • (1999) Cell , vol.96 , pp. 245
    • Vaux, D.1    Korsmeyer, S.2
  • 69
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine AJ. p53, the cellular gatekeeper for growth and division. Cell. 1997;88:323.
    • (1997) Cell , vol.88 , pp. 323
    • Levine, A.J.1
  • 70
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • Miyashita T, Reed JC. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell. 1995;80:293.
    • (1995) Cell , vol.80 , pp. 293
    • Miyashita, T.1    Reed, J.C.2
  • 71
    • 0028292480 scopus 로고
    • Identification of a p53-dependent negative response element in the bcl-2 gene
    • Miyashita T, Harigai M, Hanada M, Reed JC. Identification of a p53-dependent negative response element in the bcl-2 gene. Cancer Res. 1994;54:3131.
    • (1994) Cancer Res , vol.54 , pp. 3131
    • Miyashita, T.1    Harigai, M.2    Hanada, M.3    Reed, J.C.4
  • 72
    • 0026699666 scopus 로고
    • Transcriptional activation of the tumor necrosis factor alpha-inducible zinc finger protein, A20, is mediated by kappa B elements
    • Krikos A, Laherty CD, Dixit VM. Transcriptional activation of the tumor necrosis factor alpha-inducible zinc finger protein, A20, is mediated by kappa B elements. J Biol Chem. 1992;267:17,971.
    • (1992) J Biol Chem , vol.267 , pp. 17971
    • Krikos, A.1    Laherty, C.D.2    Dixit, V.M.3
  • 73
    • 0029914174 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 1 blocks p53-mediated apoptosis through the induction of the A20 gene
    • Fries KL, Miller WE, Raab-Traub N. Epstein-Barr virus latent membrane protein 1 blocks p53-mediated apoptosis through the induction of the A20 gene. J Virol. 1996;70:8653.
    • (1996) J Virol , vol.70 , pp. 8653
    • Fries, K.L.1    Miller, W.E.2    Raab-Traub, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.