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Volumn 240, Issue 1, 1998, Pages 93-99

Activation of a Ras-MAPK-dependent pathway by Epstein-Barr virus latent membrane protein 1 is essential for cellular transformation

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MUTANT PROTEIN; RAS PROTEIN; VIRUS PROTEIN;

EID: 0032484473     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1997.8901     Document Type: Article
Times cited : (135)

References (48)
  • 1
    • 0025890062 scopus 로고
    • Early events in Epstein-Barr virus infection of human B lymphocytes
    • Alfieri C., Birkenbach M., Kieff E. Early events in Epstein-Barr virus infection of human B lymphocytes. Virology. 181:1991;595-608.
    • (1991) Virology , vol.181 , pp. 595-608
    • Alfieri, C.1    Birkenbach, M.2    Kieff, E.3
  • 2
    • 0024345877 scopus 로고
    • Epstein-Barr virus latent gene expression during the initiation of B cell immortalization
    • Allday M. J., Crawford D. H., Griffin B. E. Epstein-Barr virus latent gene expression during the initiation of B cell immortalization. J. Gen. Virol. 70:1989;1755-1764.
    • (1989) J. Gen. Virol. , vol.70 , pp. 1755-1764
    • Allday, M.J.1    Crawford, D.H.2    Griffin, B.E.3
  • 3
    • 0029121548 scopus 로고
    • Latent membrane protein-1 induces cyclin D2 expression, pRb hyperphosphorylation, and loss of TGF-β1-mediated growth inhibition in EBV-positive B cells
    • Arvanitakis L., Yaseen N., Sharma S. Latent membrane protein-1 induces cyclin D2 expression, pRb hyperphosphorylation, and loss of TGF-β1-mediated growth inhibition in EBV-positive B cells. J. Immunol. 155:1995;1047-1056.
    • (1995) J. Immunol. , vol.155 , pp. 1047-1056
    • Arvanitakis, L.1    Yaseen, N.2    Sharma, S.3
  • 4
    • 0023879695 scopus 로고
    • Transformation of Balb 3T3 cells by the BNLF-1 gene of Epstein-Barr virus
    • Baichwal V. R., Sugden B. Transformation of Balb 3T3 cells by the BNLF-1 gene of Epstein-Barr virus. Oncogene. 2:1988;461-467.
    • (1988) Oncogene , vol.2 , pp. 461-467
    • Baichwal, V.R.1    Sugden, B.2
  • 6
    • 0024336625 scopus 로고
    • Epstein-Barr virus latent infection membrane protein induces vimentin expression in human B-cell lines
    • Birkenbach M., Liebowitz D., Wang F., Sample J., Kieff E. Epstein-Barr virus latent infection membrane protein induces vimentin expression in human B-cell lines. J. Virol. 63:1989;4079-4084.
    • (1989) J. Virol. , vol.63 , pp. 4079-4084
    • Birkenbach, M.1    Liebowitz, D.2    Wang, F.3    Sample, J.4    Kieff, E.5
  • 7
    • 0030011643 scopus 로고    scopus 로고
    • Epstein-Barr virus nuclear antigen 2 and latent membrane protein independently transactivate p53 through induction of NF-κB activity
    • Chen W., Cooper N. R. Epstein-Barr virus nuclear antigen 2 and latent membrane protein independently transactivate p53 through induction of NF-κB activity. J. Virol. 70:1996;4849-4853.
    • (1996) J. Virol. , vol.70 , pp. 4849-4853
    • Chen, W.1    Cooper, N.R.2
  • 8
    • 0028228616 scopus 로고
    • Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
    • Cowley S., Paterson H., Kemp P., Marshall C. J. Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell. 77:1994;841-852.
    • (1994) Cell , vol.77 , pp. 841-852
    • Cowley, S.1    Paterson, H.2    Kemp, P.3    Marshall, C.J.4
  • 9
    • 0025271424 scopus 로고
    • Epstein-Barr virus latent membrane protein inhibits human epithelial cell differentiation
    • Dawson C. W., Rickinson A. B., Young L. S. Epstein-Barr virus latent membrane protein inhibits human epithelial cell differentiation. Nature. 344:1990;777-780.
    • (1990) Nature , vol.344 , pp. 777-780
    • Dawson, C.W.1    Rickinson, A.B.2    Young, L.S.3
  • 11
    • 0025325549 scopus 로고
    • Morphological transformation of human keratinocytes expressing the LMP gene of Epstein-Barr virus
    • Fahraeus R., Rymo L., Rhim J. S., Klein G. Morphological transformation of human keratinocytes expressing the LMP gene of Epstein-Barr virus. Nature. 345:1990;447-449.
    • (1990) Nature , vol.345 , pp. 447-449
    • Fahraeus, R.1    Rymo, L.2    Rhim, J.S.3    Klein, G.4
  • 12
    • 0027458762 scopus 로고
    • Expression of Epstein-Barr virus latent membrane protein influences self renewal and differentiation in a multipotential murine haemopoietic stem cell line
    • Fairbairn L. J., Stewart J. P., Hampson I. N., Arrand J. R., Dexter T. M. Expression of Epstein-Barr virus latent membrane protein influences self renewal and differentiation in a multipotential murine haemopoietic stem cell line. J. Gen. Virol. 1993;247-254.
    • (1993) J. Gen. Virol. , pp. 247-254
    • Fairbairn, L.J.1    Stewart, J.P.2    Hampson, I.N.3    Arrand, J.R.4    Dexter, T.M.5
  • 13
    • 0023715225 scopus 로고
    • Inhibition of NIH 3T3 cell proliferation by a mutantras
    • Feig L. A., Cooper G. M. Inhibition of NIH 3T3 cell proliferation by a mutantras. Mol. Cell. Biol. 8:1988;3235-3243.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 3235-3243
    • Feig, L.A.1    Cooper, G.M.2
  • 16
    • 0026700212 scopus 로고
    • Epstein-Barr virus latent membrane protein transactivates the human immunodeficiency virus type 1 long terminal repeat through induction of NF-κB activity
    • Hammarskjöld M.-L., Simurda M. C. Epstein-Barr virus latent membrane protein transactivates the human immunodeficiency virus type 1 long terminal repeat through induction of NF-κB activity. J. Virol. 66:1992;6496-6501.
    • (1992) J. Virol. , vol.66 , pp. 6496-6501
    • Hammarskjöld, M.-L.1    Simurda, M.C.2
  • 17
    • 0024375760 scopus 로고
    • Genetic analysis of immortalizing functions of Epstein-Barr virus in human B lymphocytes
    • Hammerschmidt W., Sugden B. Genetic analysis of immortalizing functions of Epstein-Barr virus in human B lymphocytes. Nature. 340:1989;393-397.
    • (1989) Nature , vol.340 , pp. 393-397
    • Hammerschmidt, W.1    Sugden, B.2
  • 18
    • 0025772343 scopus 로고
    • Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death
    • Henderson S., Rowe M., Gregory C., Croom-Carter D., Wang F., Longnecker R., Kieff E., Rickinson A. Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death. Cell. 65:1991;1107-1115.
    • (1991) Cell , vol.65 , pp. 1107-1115
    • Henderson, S.1    Rowe, M.2    Gregory, C.3    Croom-Carter, D.4    Wang, F.5    Longnecker, R.6    Kieff, E.7    Rickinson, A.8
  • 20
    • 0028853402 scopus 로고
    • The Epstein-Barr virus latent membrane protein-1 (LMP1) mediates activation of NF-κB and cell surface phenotype via two effector regions in its carboxy-terminal cytoplasmic domain
    • Huen D. S., Henderson S. A., Croom-Carter D., Rowe M. The Epstein-Barr virus latent membrane protein-1 (LMP1) mediates activation of NF-κB and cell surface phenotype via two effector regions in its carboxy-terminal cytoplasmic domain. Oncogene. 10:1995;549-560.
    • (1995) Oncogene , vol.10 , pp. 549-560
    • Huen, D.S.1    Henderson, S.A.2    Croom-Carter, D.3    Rowe, M.4
  • 22
    • 0026425673 scopus 로고
    • Acquired immunodeficiency syndrome and non-Hodgkin's lymphomas
    • Karp J. E., Broder S. Acquired immunodeficiency syndrome and non-Hodgkin's lymphomas. Cancer Res. 51:1991;4743-4756.
    • (1991) Cancer Res. , vol.51 , pp. 4743-4756
    • Karp, J.E.1    Broder, S.2
  • 23
    • 0027449255 scopus 로고
    • Epstein-Barr virus latent membrane protein 1 is essential for B-lymphocyte growth transformation
    • Kaye K. M., Izumi K. M., Kieff E. Epstein-Barr virus latent membrane protein 1 is essential for B-lymphocyte growth transformation. Proc. Natl. Acad. Sci. USA. 90:1993;9150-9154.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 9150-9154
    • Kaye, K.M.1    Izumi, K.M.2    Kieff, E.3
  • 24
    • 0024392383 scopus 로고
    • Viral latency and transformation: The strategy of Epstein-Barr virus
    • Klein G. Viral latency and transformation: The strategy of Epstein-Barr virus. Cell. 58:1989;5-8.
    • (1989) Cell , vol.58 , pp. 5-8
    • Klein, G.1
  • 26
    • 0026465540 scopus 로고
    • The Epstein-Barr virus LMP1 gene product induces A20 zinc finger protein expression by activating nuclear factor kB
    • Laherty C. D., Hu H. M., Opipari A. W., Wang F., Dixit V. M. The Epstein-Barr virus LMP1 gene product induces A20 zinc finger protein expression by activating nuclear factor kB. J. Biol. Chem. 267:1992;24157-24160.
    • (1992) J. Biol. Chem. , vol.267 , pp. 24157-24160
    • Laherty, C.D.1    Hu, H.M.2    Opipari, A.W.3    Wang, F.4    Dixit, V.M.5
  • 27
    • 0022501165 scopus 로고
    • Orientation and patching of the latent infection membrane protein encoded by Epstein-Barr virus
    • Liebowitz D., Wang D., Kieff E. Orientation and patching of the latent infection membrane protein encoded by Epstein-Barr virus. J. Virol. 58:1986;233-237.
    • (1986) J. Virol. , vol.58 , pp. 233-237
    • Liebowitz, D.1    Wang, D.2    Kieff, E.3
  • 28
    • 0028305758 scopus 로고
    • T cell dependent B cell activating properties of antibody-coated small latex beads: A new model for B cell activation
    • Luxembourg A. T., Cooper N. R. T cell dependent B cell activating properties of antibody-coated small latex beads: A new model for B cell activation. J. Immunol. 153:1994;604-614.
    • (1994) J. Immunol. , vol.153 , pp. 604-614
    • Luxembourg, A.T.1    Cooper, N.R.2
  • 29
    • 0022217534 scopus 로고
    • Epstein-Barr virus-encoded protein found in plasma membranes of transformed cells
    • Mann K. P., Staunton D., Thorley-Lawson D. A. Epstein-Barr virus-encoded protein found in plasma membranes of transformed cells. J. Virol. 55:1985;710-720.
    • (1985) J. Virol. , vol.55 , pp. 710-720
    • Mann, K.P.1    Staunton, D.2    Thorley-Lawson, D.A.3
  • 30
    • 0025750139 scopus 로고
    • The Epstein-Barr virus nuclear protein encoded by the leader of the EBNA RNAs is important in B-lymphocyte transformation
    • Mannick J. B., Cohen J. I., Birkenbach M., Marchini A., Kieff E. The Epstein-Barr virus nuclear protein encoded by the leader of the EBNA RNAs is important in B-lymphocyte transformation. J. Virol. 65:1991;6826-6837.
    • (1991) J. Virol. , vol.65 , pp. 6826-6837
    • Mannick, J.B.1    Cohen, J.I.2    Birkenbach, M.3    Marchini, A.4    Kieff, E.5
  • 31
    • 0027407079 scopus 로고
    • All three domains of the Epstein-Barr virus-encoded latent membrane protein LMP-1 are required for transformation of Rat-1 fibroblasts
    • Moorthy R. K., Thorley-Lawson D. A. All three domains of the Epstein-Barr virus-encoded latent membrane protein LMP-1 are required for transformation of Rat-1 fibroblasts. J. Virol. 67:1993;1638-1646.
    • (1993) J. Virol. , vol.67 , pp. 1638-1646
    • Moorthy, R.K.1    Thorley-Lawson, D.A.2
  • 33
    • 0028878977 scopus 로고
    • The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family
    • Mosialos G., Birkenbach M., Yalamanchili R., VanArsdale T., Ware C., Kieff E. The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family. Cell. 80:1995;389-399.
    • (1995) Cell , vol.80 , pp. 389-399
    • Mosialos, G.1    Birkenbach, M.2    Yalamanchili, R.3    Vanarsdale, T.4    Ware, C.5    Kieff, E.6
  • 35
    • 0344695779 scopus 로고
    • Selection for animal cells that express theEscherichia coli
    • Mulligan R. C., Berg P. Selection for animal cells that express theEscherichia coli. Proc. Natl. Acad. Sci. USA. 78:1981;2072-2076.
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 2072-2076
    • Mulligan, R.C.1    Berg, P.2
  • 36
    • 0028173712 scopus 로고
    • The Epstein-Barr virus latent membrane protein-1 (LMP1) induces interleukin-10 production in Burkitt lymphoma lines
    • Nakagomi H., Dolcetti R., Bejarano M. T., Pisa P., Kiessling R., Masucci M. G. The Epstein-Barr virus latent membrane protein-1 (LMP1) induces interleukin-10 production in Burkitt lymphoma lines. Int. J. Cancer. 57:1994;240-244.
    • (1994) Int. J. Cancer , vol.57 , pp. 240-244
    • Nakagomi, H.1    Dolcetti, R.2    Bejarano, M.T.3    Pisa, P.4    Kiessling, R.5    Masucci, M.G.6
  • 38
    • 0026083019 scopus 로고
    • Expression of Epstein-Barr virus latent gene products in tumour cells of Hodgkin's disease
    • Pallesen G., Hamilton-Dutoit S. J., Rowe M., Young L. S. Expression of Epstein-Barr virus latent gene products in tumour cells of Hodgkin's disease. Lancet. 337:1991;320-322.
    • (1991) Lancet , vol.337 , pp. 320-322
    • Pallesen, G.1    Hamilton-Dutoit, S.J.2    Rowe, M.3    Young, L.S.4
  • 39
    • 0026733638 scopus 로고
    • Transient expression of the Epstein-Barr virus LMP1 gene in human primary B cells induces cellular activation and DNA synthesis
    • Peng M., Lundgren E. Transient expression of the Epstein-Barr virus LMP1 gene in human primary B cells induces cellular activation and DNA synthesis. Oncogene. 7:1992;1775-1782.
    • (1992) Oncogene , vol.7 , pp. 1775-1782
    • Peng, M.1    Lundgren, E.2
  • 41
    • 0024474939 scopus 로고
    • Post-translational isoprenylation of cellular proteins is altered in response to mevalonate availability
    • Repko E. M., Maltese W. A. Post-translational isoprenylation of cellular proteins is altered in response to mevalonate availability. J. Biol. Chem. 264:1989;9945-9952.
    • (1989) J. Biol. Chem. , vol.264 , pp. 9945-9952
    • Repko, E.M.1    Maltese, W.A.2
  • 42
  • 45
    • 0026058185 scopus 로고
    • Aggressive peripheral T-cell lymphomas containing Epstein-Barr viral DNA: A clinicopathologic and molecular analysis
    • Su I.-J., Hsieh H.-C., Lin K.-H., Uen W.-C., Kao C.-L., Chen C.-J., Cheng A.-L., Kadin M. E., Chen J.-Y. Aggressive peripheral T-cell lymphomas containing Epstein-Barr viral DNA: A clinicopathologic and molecular analysis. Blood. 77:1991;799-808.
    • (1991) Blood , vol.77 , pp. 799-808
    • Su, I.-J.1    Hsieh, H.-C.2    Lin, K.-H.3    Uen, W.-C.4    Kao, C.-L.5    Chen, C.-J.6    Cheng, A.-L.7    Kadin, M.E.8    Chen, J.-Y.9
  • 46
    • 0027479649 scopus 로고
    • Epstein-Barr virus nuclear proteins EBNA-3A and EBNA-3C are essential for B-lymphocyte growth transformation
    • Tomkinson B., Robertson E., Kieff E. Epstein-Barr virus nuclear proteins EBNA-3A and EBNA-3C are essential for B-lymphocyte growth transformation. J. Virol. 67:1993;2014-2025.
    • (1993) J. Virol. , vol.67 , pp. 2014-2025
    • Tomkinson, B.1    Robertson, E.2    Kieff, E.3
  • 47
    • 0028270718 scopus 로고
    • Mitogen-activated protein kinase/extracellular signal-regulated protein kinase activation by oncogenes, serum, and 12-O
    • Troppmair J., Bruder J. T., Munoz H., Lloyd P. A., Kyriakis J., Banerjee P., Avruch J., Rapp U. R. Mitogen-activated protein kinase/extracellular signal-regulated protein kinase activation by oncogenes, serum, and 12-O. J. Biol. Chem. 269:1994;7030-7035.
    • (1994) J. Biol. Chem. , vol.269 , pp. 7030-7035
    • Troppmair, J.1    Bruder, J.T.2    Munoz, H.3    Lloyd, P.A.4    Kyriakis, J.5    Banerjee, P.6    Avruch, J.7    Rapp, U.R.8
  • 48
    • 0022309824 scopus 로고
    • An Epstein-Barr virus membrane protein expressed in immortalized lymphocytes transforms established rodent cells
    • Wang D., Liebowitz D., Kieff E. An Epstein-Barr virus membrane protein expressed in immortalized lymphocytes transforms established rodent cells. Cell. 43:1985;831-840.
    • (1985) Cell , vol.43 , pp. 831-840
    • Wang, D.1    Liebowitz, D.2    Kieff, E.3


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