Inhibition of IκB kinase activity by sodium salicylate in vitro does not reflect its inhibitory mechanism in intact cells

Journal of Biological Chemistry

Volumn 275, Issue 15, 2000, Pages 10925-10929

  Alpert, Deborah ^a   Vilček, Jan ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ARSENITE SODIUM; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN KAPPA CHAIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MYELIN BASIC PROTEIN; RECOMBINANT INTERLEUKIN 1ALPHA; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; SALICYLATE SODIUM; I KAPPA B; IMIDAZOLE DERIVATIVE; INTERLEUKIN 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE (CALCIUM,CALMODULIN); PYRIDINE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CATALYSIS; CELL STRAIN COS1; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; FIBROBLAST; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; DRUG ANTAGONISM;

ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; COS CELLS; HUMANS; I-KAPPA B PROTEINS; IMIDAZOLES; INTERLEUKIN-1; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRIDINES; SODIUM SALICYLATE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0034646480     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.15.10925     Document Type: Article

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