Salicylic acid and aspirin inhibit the activity of RSK2 kinase and repress RSK2-dependent transcription of cyclic AMP response element binding protein- and NF-κB-responsive genes

Journal of Immunology

Volumn 163, Issue 10, 1999, Pages 5608-5616

  Stevenson, Mary Ann ^b   Zhao, Mei Juan ^b   Asea, Alexzander ^b   Coleman, C Norman ^b   Calderwood, Stuart K ^a,b  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; NONSTEROID ANTIINFLAMMATORY AGENT; S6 KINASE; SALICYLIC ACID; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CELL STRAIN 3T3; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ASSAY; ENZYME INHIBITION; GENE CONTROL; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

3T3 CELLS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; ENZYME ACTIVATION; ENZYME INHIBITORS; HELA CELLS; HUMANS; INTERPHASE; LIPOPOLYSACCHARIDES; MICE; MITOGENS; MONOCYTES; NF-KAPPA B; PHOSPHOPROTEINS; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); RIBOSOMAL PROTEIN S6 KINASES; SALICYLIC ACID; SUBSTRATE SPECIFICITY; TRANSCRIPTION, GENETIC;

EID: 0033571738     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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