HIV protease as a target for retrovirus vector-mediated gene therapy

Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology

Volumn 1477, Issue 1-2, 2000, Pages 168-188

  Todd, Stephen ^a   Anderson, Carol Gay ^c   Jolly, Douglas J ^c   Craik, Charles S ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Dominant negative; Gene therapy; HIV protease inhibitor; Lentivirus; Retrovirus vector; Transdominant

Indexed keywords

PROTEINASE; VIRUS VECTOR;

ANTIVIRAL ACTIVITY; ENZYME INHIBITION; ENZYME STRUCTURE, FUNCTION AND VARIABILITY; GENE THERAPY; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; REVIEW;

AMINO ACID SEQUENCE; CARBAMATES; GENE THERAPY; GENETIC VECTORS; HIV PROTEASE; HIV PROTEASE INHIBITORS; HIV-1; HUMANS; INDINAVIR; LENTIVIRUS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NELFINAVIR; RETROVIRIDAE; RITONAVIR; SAQUINAVIR; SULFONAMIDES; TRANSFECTION;

LENTIVIRUS; RNA VIRUSES; UNIDENTIFIED RETROVIRUS;

EID: 0034615557     PISSN: 01674838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4838(99)00272-1     Document Type: Review

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