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1
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14744304517
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A new generation of animal cell expression vectors based on the Semliki Forest virus replicon
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Liljestrsöm P, Garoff H: A new generation of animal cell expression vectors based on the Semliki Forest virus replicon. Bio-Technology 1993, 9:1356-1361.
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(1993)
Bio-Technology
, vol.9
, pp. 1356-1361
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Liljestrsöm, P.1
Garoff, H.2
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2
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0024514346
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Sindbis virus: An efficient broad host range vector for gene expression in animal cells
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Xiong C, Levis R, Shen P, Schlesinger S, Rice CM, Huang HV: Sindbis virus: an efficient broad host range vector for gene expression in animal cells. Science 1989, 243:1188-1191.
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(1989)
Science
, vol.243
, pp. 1188-1191
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Xiong, C.1
Levis, R.2
Shen, P.3
Schlesinger, S.4
Rice, C.M.5
Huang, H.V.6
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3
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0024403231
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In vitro synthesis of infectious Venezuelan equine encephalitis virus RNA from a cDNA clone: Analysis of a viable deletion mutant
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Davis NL, Willis LW, Smith JF, Johnston RE: In vitro synthesis of infectious Venezuelan equine encephalitis virus RNA from a cDNA clone: analysis of a viable deletion mutant. Virology 1989, 171:189-204.
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(1989)
Virology
, vol.171
, pp. 189-204
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Davis, N.L.1
Willis, L.W.2
Smith, J.F.3
Johnston, R.E.4
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4
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14744292350
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Semliki Forest virus expression system: Production of conditionally infectious recombinant particles
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Berglund P, Sjöberg M, Garoff H, Atkins GJ, Sheahan BJ, Liljeström P: Semliki Forest virus expression system: production of conditionally infectious recombinant particles. Bio-Technology 1993, 11:916-920.
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(1993)
Bio-Technology
, vol.11
, pp. 916-920
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Berglund, P.1
Sjöberg, M.2
Garoff, H.3
Atkins, G.J.4
Sheahan, B.J.5
Liljeström, P.6
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5
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0028239412
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A cell line that expresses a reporter gene in response to infection by Sindbis virus: A protype for detection of positive strand RNA viruses
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Olivo PD, Frolov I, Schlesinger S: A cell line that expresses a reporter gene in response to infection by Sindbis virus: a protype for detection of positive strand RNA viruses. Virology 1994, 198:381-384.
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(1994)
Virology
, vol.198
, pp. 381-384
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Olivo, P.D.1
Frolov, I.2
Schlesinger, S.3
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7
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0029045376
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A Sindbis virus mRNA polynucleotide vector achieves prolonged and high level heterologous gene expression in vivo
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Johanning FW, Conry RM, LoBuglio AF, Wright M, Sumerel LA, Pike MJ, Curiel DT: A Sindbis virus mRNA polynucleotide vector achieves prolonged and high level heterologous gene expression in vivo. Nucleic Acids Res 1995, 23:1495-1501.
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(1995)
Nucleic Acids Res
, vol.23
, pp. 1495-1501
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Johanning, F.W.1
Conry, R.M.2
Lobuglio, A.F.3
Wright, M.4
Sumerel, L.A.5
Pike, M.J.6
Curiel, D.T.7
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8
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0028982231
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A plasmid-based self-amplifying Sindbis virus vector
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Herweijer H, Latendresse JS, Williams P, Zhang G, Danko I, Schlesinger S, Wolff JA: A plasmid-based self-amplifying Sindbis virus vector. Hum Gene Ther 1995, 6:1161-1167.
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(1995)
Hum Gene Ther
, vol.6
, pp. 1161-1167
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Herweijer, H.1
Latendresse, J.S.2
Williams, P.3
Zhang, G.4
Danko, I.5
Schlesinger, S.6
Wolff, J.A.7
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9
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0029655275
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Sindbis virus DNA-based expression vectors: Utility for in vitro and in vivo gene transfer
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Dubensky TW, Driver DA, Polo JM, Belli BA, Latham EM, Ibanez CE, Chada S, Brumm D, Banks TA, Mento SJ et al.: Sindbis virus DNA-based expression vectors: utility for in vitro and in vivo gene transfer. J Virol 1996, 70:508-519.
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(1996)
J Virol
, vol.70
, pp. 508-519
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Dubensky, T.W.1
Driver, D.A.2
Polo, J.M.3
Belli, B.A.4
Latham, E.M.5
Ibanez, C.E.6
Chada, S.7
Brumm, D.8
Banks, T.A.9
Mento, S.J.10
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10
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0028152741
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A significantly improved Semliki Forest virus expression system based on translation enhancer segments from the viral capsid gene
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Sjöberg EM, Suomalainen M, Garoff H: A significantly improved Semliki Forest virus expression system based on translation enhancer segments from the viral capsid gene. Bio-Technology 1994, 12:1127-1131.
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(1994)
Bio-Technology
, vol.12
, pp. 1127-1131
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Sjöberg, E.M.1
Suomalainen, M.2
Garoff, H.3
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11
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0028171032
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Translation of Sindbis virus mRNA: Effects of sequences downstream of the initiating codon
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Frolov I, Schlesinger S: Translation of Sindbis virus mRNA: effects of sequences downstream of the initiating codon. J Virol 1994, 68:8111-8117.
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(1994)
J Virol
, vol.68
, pp. 8111-8117
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Frolov, I.1
Schlesinger, S.2
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12
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8944255627
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The translation-enhancing region of the Semliki Forest virus subgenome is only functional in the virus-infected cell
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Sjöberg EM, Garoff H: The translation-enhancing region of the Semliki Forest virus subgenome is only functional in the virus-infected cell. J Gen Virol 1996, 77:1323-1327.
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(1996)
J Gen Virol
, vol.77
, pp. 1323-1327
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Sjöberg, E.M.1
Garoff, H.2
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13
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0030068269
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Translation of Sindbis virus mRNA: Analysis of sequences downstream of the initiating codon that enhance translation
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Frolov I, Schlesinger S: Translation of Sindbis virus mRNA: analysis of sequences downstream of the initiating codon that enhance translation. J Virol 1996, 70:1182-1190.
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(1996)
J Virol
, vol.70
, pp. 1182-1190
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Frolov, I.1
Schlesinger, S.2
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14
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0027986768
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Novel infectious particles generated by expression of the vesicular stomatitis virus glycoprotein from a self-replicating RNA
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Rolls MM, Webster P, Balba NH, Rose JK: Novel infectious particles generated by expression of the vesicular stomatitis virus glycoprotein from a self-replicating RNA. Cell 1994, 79:497-508.
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(1994)
Cell
, vol.79
, pp. 497-508
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Rolls, M.M.1
Webster, P.2
Balba, N.H.3
Rose, J.K.4
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15
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0031060529
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Efficient multiplication of a Semliki Forest virus chimera containing Sindbis virus spikes
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Smyth J, Suomalainen M, Garoff H: Efficient multiplication of a Semliki Forest virus chimera containing Sindbis virus spikes. J Virol 1997, 71:818-823.
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(1997)
J Virol
, vol.71
, pp. 818-823
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Smyth, J.1
Suomalainen, M.2
Garoff, H.3
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16
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0029907961
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Production of infectious recombinant Moloney murine leukemia virus particles in BHK cells using Semliki Forest virus-derived RNA expression vectors
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Li K-J, Garoff H: Production of infectious recombinant Moloney murine leukemia virus particles in BHK cells using Semliki Forest virus-derived RNA expression vectors. Proc Natl Acad Sci USA 1996, 93:11658-11663. This paper describes the in vivo packaging of retrovirus particles in baby hamster kidney (BHK) cells with the aid of the Semliki Forest virus (SFV) replicon. RNA from retroviral genes on separate SFV vectors transfected into BHK cells resulted in high titer retroviral yields, showing protease and reverse transcriptase activities. This technology opens up new possibilities for using retroviruses in gene therapy.
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(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 11658-11663
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Li, K.-J.1
Garoff, H.2
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17
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Alphavirus expression systems
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Liljeström P: Alphavirus expression systems. Curr Opin Biotechnol 1994, 5:495-500.
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(1994)
Curr Opin Biotechnol
, vol.5
, pp. 495-500
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Liljeström, P.1
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18
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13044314866
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Applications of the SFV system for studies on receptors and ion channels
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Lundstrom K: Applications of the SFV system for studies on receptors and ion channels. Focus 1996, 18:53-56.
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(1996)
Focus
, vol.18
, pp. 53-56
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Lundstrom, K.1
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19
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0030614993
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Radiolabelling of the rat P2X4 purinoceptor: Evidence for allosteric interactions of purinoceptor antagonists and monovalent cations with P2X purinoreceptors
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Michel AD, Miller K, Lundstrom K, Buell G, Humphrey PPA: Radiolabelling of the rat P2X4 purinoceptor: evidence for allosteric interactions of purinoceptor antagonists and monovalent cations with P2X purinoreceptors. Mol Pharmacol 1997, 51:524-532.
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(1997)
Mol Pharmacol
, vol.51
, pp. 524-532
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Michel, A.D.1
Miller, K.2
Lundstrom, K.3
Buell, G.4
Humphrey, P.P.A.5
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20
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0343117896
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Site-directed mutagenesis of the human neurokinin-1 receptor
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in press
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Lundstrom K, Hawcock T, Vargas A, Ward P, Naylor A, Thomas P: Site-directed mutagenesis of the human neurokinin-1 receptor. Eur J Pharmacol 1997, in press.
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(1997)
Eur J Pharmacol
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Lundstrom, K.1
Hawcock, T.2
Vargas, A.3
Ward, P.4
Naylor, A.5
Thomas, P.6
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21
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0030979789
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A retention signal necessary and sufficient for Golgi localization maps to the cytoplasmic tail of a Bunyaviridae membrane glycoprotein
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Andersson AM, Melin L, Bean A, Pettersson RF: A retention signal necessary and sufficient for Golgi localization maps to the cytoplasmic tail of a Bunyaviridae membrane glycoprotein. J Virol 1997, 71:4717-4727.
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(1997)
J Virol
, vol.71
, pp. 4717-4727
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Andersson, A.M.1
Melin, L.2
Bean, A.3
Pettersson, R.F.4
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22
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0028595944
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Membrane insertion and intracellular transport of yeast syntaxin Sso2p in mammalian cells
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Jäntti J, Kerönen S, Toikkanen J, Kuismanen E, Ehnholm C, Söderlund H, Olkkonen VM: Membrane insertion and intracellular transport of yeast syntaxin Sso2p in mammalian cells. J Cell Sci 1995, 107:3623-3633.
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(1995)
J Cell Sci
, vol.107
, pp. 3623-3633
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Jäntti, J.1
Kerönen, S.2
Toikkanen, J.3
Kuismanen, E.4
Ehnholm, C.5
Söderlund, H.6
Olkkonen, V.M.7
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23
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0029812077
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Expression and analysis of presenilin 1 in a human neuronal system: Localization in cell bodies and dendrites
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Cook DG, Sung JC, Golde TE, Felsenstein KM, Wojczyk BS, Tanzi RE, Trojanowski JQ, Lee VM-Y, Doms RW: Expression and analysis of presenilin 1 in a human neuronal system: localization in cell bodies and dendrites. Proc Natl Acad Sci USA 1996, 93:9223-9228. In this study, the familial Alzheimer's disease related gene presenilin 1 was expressed in BHK cells and NT2N primary neurons by infection with recombinant Semliki Forest virus particles. Immunoreactive presenilin 1 was detected in cell bodies and dendrites of the neurons and could be colocalized with the rough endoplasmic reticulum marker protein calnexin in BHK cells.
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(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 9223-9228
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Cook, D.G.1
Sung, J.C.2
Golde, T.E.3
Felsenstein, K.M.4
Wojczyk, B.S.5
Tanzi, R.E.6
Trojanowski, J.Q.7
Lee, V.M.-Y.8
Doms, R.W.9
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24
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0031037713
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Expression and intracellular localization of catechol-o-methyltransferase in transfected mammalian cells
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Ulmanen I, Peränen J, Tenhunen J, Tilgmann C, Karhunen T, Panula P, Bernasconi L, Aubry J-P, Lundstrom K: Expression and intracellular localization of catechol-o-methyltransferase in transfected mammalian cells. Eur J Biochem 1997, 243:452-459.
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(1997)
Eur J Biochem
, vol.243
, pp. 452-459
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Ulmanen, I.1
Peränen, J.2
Tenhunen, J.3
Tilgmann, C.4
Karhunen, T.5
Panula, P.6
Bernasconi, L.7
Aubry, J.-P.8
Lundstrom, K.9
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25
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0029877873
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Transient expression of a mitochondrial precursor protein: A new approach to study mitochondrial protein import in cells of higher eukaryotes
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Huckriede A, Heikema A, Wilschut J, Agsteribbe E: Transient expression of a mitochondrial precursor protein: a new approach to study mitochondrial protein import in cells of higher eukaryotes. Eur J Biochem 1996, 237:288-294.
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Eur J Biochem
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Huckriede, A.1
Heikema, A.2
Wilschut, J.3
Agsteribbe, E.4
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27
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0026509198
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Infectious Sindbis virus transient expression vectors for studying antigen processing and presentation
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Hahn CS, Hahn YS, Braciale TJ, Rice CM: Infectious Sindbis virus transient expression vectors for studying antigen processing and presentation. Proc Natl Acad Sci USA 1992, 89:2679-2683.
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(1992)
Proc Natl Acad Sci USA
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Hahn, C.S.1
Hahn, Y.S.2
Braciale, T.J.3
Rice, C.M.4
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28
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0028962824
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Generation of cytotoxic and humoral immune responses by nonreplicative recombinant Semliki Forest virus
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Zhou X, Berglund P, Zhao H, Liljeström P, Jondal, M: Generation of cytotoxic and humoral immune responses by nonreplicative recombinant Semliki Forest virus. Proc Natl Acad Sci USA 1995, 92:3009-3013.
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(1995)
Proc Natl Acad Sci USA
, vol.92
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Zhou, X.1
Berglund, P.2
Zhao, H.3
Liljeström, P.4
Jondal, M.5
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29
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0028173338
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Self-replicating Semliki Forest virus RNA as recombinant vaccine
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Zhou X, Berglund P, Rhodes G, Parker SE, Jondal M, Liljeström P: Self-replicating Semliki Forest virus RNA as recombinant vaccine. Vaccine 1994, 12:1510-1513.
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(1994)
Vaccine
, vol.12
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Zhou, X.1
Berglund, P.2
Rhodes, G.3
Parker, S.E.4
Jondal, M.5
Liljeström, P.6
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30
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0344192533
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Protection against lethal simian immunodeficiency virus SIVsmmPBj14 disease by a recombinant Semliki Forest virus gp160 vaccine and by a gp120 subunit vaccine
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Mossmann SP, Bex F, Berglund P, Arthos J, O'Neil SP, Riley D, Maul DH, Bruck C, Momin P, Burny A et al.: Protection against lethal simian immunodeficiency virus SIVsmmPBj14 disease by a recombinant Semliki Forest virus gp160 vaccine and by a gp120 subunit vaccine. J Virol 1996, 70:1953-1960. This paper describes the immunization of pigtail macaques with either recombinant SFV expressing SIV-PBj14Env gp160 or purified recombinant SIV-PBj14 gp120. The results indicated that the immunizations did not protect against virus infection but lowered the virus load in plasma and protected against the lethal challenge with SIV-PBj14 virus.
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(1996)
J Virol
, vol.70
, pp. 1953-1960
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Mossmann, S.P.1
Bex, F.2
Berglund, P.3
Arthos, J.4
O'Neil, S.P.5
Riley, D.6
Maul, D.H.7
Bruck, C.8
Momin, P.9
Burny, A.10
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31
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0029949803
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A viral vaccine vector that expresses foreign genes in lymph nodes and protects against mucosal challenge
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Davis NL, Brown KW, Johnston RE: A viral vaccine vector that expresses foreign genes in lymph nodes and protects against mucosal challenge. J Virol 1996, 70:3781-3787. This paper describes the application of Venezuelan equine encephalitis virus (VEE) as a vaccine vector. Efficient immune responses were obtained, because VEE replicates primarily in lymphoid tissue. Inoculation of VEE virus expressing the influenza virus hemagglutinin gene induced both anti-hemagglutinin IgG and IgA antibodies. The vaccinated animals showed complete protection when intranasally challenged with a virulent influenza virus strain.
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(1996)
J Virol
, vol.70
, pp. 3781-3787
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Davis, N.L.1
Brown, K.W.2
Johnston, R.E.3
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32
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0030891509
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Humoral, mucosal and cellular immunity in response to a human immunodeficiency virus type 1 immunogen expressed by a Venezuelan equine encephalitis virus vaccine vector
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Caley IJ, Betts MR, Irlbeck DM, Davis NL, Swanstrom R, Frelinger JA, Johnston RE: Humoral, mucosal and cellular immunity in response to a human immunodeficiency virus type 1 immunogen expressed by a Venezuelan equine encephalitis virus vaccine vector. J Virol 1997, 71:3031-3038.
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(1997)
J Virol
, vol.71
, pp. 3031-3038
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Caley, I.J.1
Betts, M.R.2
Irlbeck, D.M.3
Davis, N.L.4
Swanstrom, R.5
Frelinger, J.A.6
Johnston, R.E.7
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33
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8244238389
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Cloning of human IL-12 p40 and p35 DNA into the Semliki Forest virus vector: Expression of IL-12 in human tumor cells
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Zhang J, Asselin-Paturel C, Bex F, Bernard J, Chehimi J, Willems F, Caignard A, Berglund P, Liljeström P, Burny A, Chouaib S: Cloning of human IL-12 p40 and p35 DNA into the Semliki Forest virus vector: expression of IL-12 in human tumor cells. Gene Ther 1997, 4:367-374.
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(1997)
Gene Ther
, vol.4
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Zhang, J.1
Asselin-Paturel, C.2
Bex, F.3
Bernard, J.4
Chehimi, J.5
Willems, F.6
Caignard, A.7
Berglund, P.8
Liljeström, P.9
Burny, A.10
Chouaib, S.11
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34
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0030941093
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Sindbis virus replicons and Sindbis virus: Assembly of chimeras and of particles deficient in virus RNA
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Frolov I, Frolova E, Schlesinger S: Sindbis virus replicons and Sindbis virus: assembly of chimeras and of particles deficient in virus RNA. J Virol 1997, 71:2819-2829.
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(1997)
J Virol
, vol.71
, pp. 2819-2829
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Frolov, I.1
Frolova, E.2
Schlesinger, S.3
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35
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0030693198
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The Semliki Forest virus system: Receptor expression and scale-up
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in press
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Lundstrom K, Blasey HD, Hovius R, Vogel, H, Bernard A: The Semliki Forest virus system: receptor expression and scale-up. Genet Eng Biotechnol 1997, in press.
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(1997)
Genet Eng Biotechnol
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Lundstrom, K.1
Blasey, H.D.2
Hovius, R.3
Vogel, H.4
Bernard, A.5
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36
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0031026138
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SFV infection in CHO cells: Cell-type specific restrictions to productive virus entry at the cell surface
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Marsh M, Bron R: SFV infection in CHO cells: cell-type specific restrictions to productive virus entry at the cell surface. J Cell Sci 1997, 110:95-103.
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(1997)
J Cell Sci
, vol.110
, pp. 95-103
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Marsh, M.1
Bron, R.2
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37
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0030950873
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Recombinant protein production using the Semliki Forest virus expression system
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Blasey HD, Lundstrom K, Tate S, Bernard AR: Recombinant protein production using the Semliki Forest virus expression system. Cytotechnology 1997, 24:65-72. In this study the recombinant protein production is carried out at one liter scale using Semliki Forest virus vectors. Reproducible high level expression of enzymatically active human cyclo-oxygenase 2 was achieved. The conditions for efficient infection of BHK cells in suspension were optimized. Important factors were the pH and serum concentration of the medium and the multiplicity of infection.
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(1997)
Cytotechnology
, vol.24
, pp. 65-72
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Blasey, H.D.1
Lundstrom, K.2
Tate, S.3
Bernard, A.R.4
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39
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0027532285
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Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogene
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Levine B, Huang Q, Isaacs JT, Reed JC, Griffin DE, Harwick JM: Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogene. Nature 1993, 361:739-742.
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Nature
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Levine, B.1
Huang, Q.2
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Griffin, D.E.5
Harwick, J.M.6
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40
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0001360874
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Anti-apoptotic effect of Bcl-2 overexpression in Rin cells infected with Semliki Forest virus
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in press
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Lundstrom K, Pralong W, Martinou J-C: Anti-apoptotic effect of Bcl-2 overexpression in RIN cells infected with Semliki Forest virus. Apoptosis 1997, in press.
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(1997)
Apoptosis
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Lundstrom, K.1
Pralong, W.2
Martinou, J.-C.3
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41
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0031034802
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bcl-2 acts early to restrict Semliki Forest virus replication and delays virus-induced programmed cell death
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Scallan MF, Allsopp TE, Fazakerley JK: bcl-2 acts early to restrict Semliki Forest virus replication and delays virus-induced programmed cell death. J Virol 1997, 71:1583-1590.
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(1997)
J Virol
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Scallan, M.F.1
Allsopp, T.E.2
Fazakerley, J.K.3
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42
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0018841042
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Establishment and maintenance of persistent infection by Sindbis virus in BHK cells
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Weiss B, Rosenthal R, Schlesinger S: Establishment and maintenance of persistent infection by Sindbis virus in BHK cells. J Virol 1980, 33:463-474.
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(1980)
J Virol
, vol.33
, pp. 463-474
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Weiss, B.1
Rosenthal, R.2
Schlesinger, S.3
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43
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0031550546
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Identification of mutations in a Sindbis virus variant able to establish persistent infection in BHK cells. The importance of a mutation in the nsP2 gene
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Dryga SA, Dryga OA, Schlesinger S: Identification of mutations in a Sindbis virus variant able to establish persistent infection in BHK cells. The importance of a mutation in the nsP2 gene. Virology 1997, 228:74-83. This paper describes the genetic background for the phenotype of a Sindbis virus that can persistently infect cultures of BHK cells. A single point mutation (Pro726→Ser) in the nonstructural P2 (nsP2) gene was able to establish persistent infection in BHK cells. Introduction of the nsP2 mutation in the Sindbis virus vector resulted in higher levels of β-galactosidase expression.
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(1997)
Virology
, vol.228
, pp. 74-83
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Dryga, S.A.1
Dryga, O.A.2
Schlesinger, S.3
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44
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0030011522
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Functional significance of the nuclear-targeting and NTP-binding motifs of Semliki Forest virus nonstructural protein nsP2
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Rikkonen M: Functional significance of the nuclear-targeting and NTP-binding motifs of Semliki Forest virus nonstructural protein nsP2. Virology 1996, 218:352-361.
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Virology
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Infectious enveloped RNA virus antigenic chimeras
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London SD, Schmaljohn AL, Dalrymple JM, Rice CM: Infectious enveloped RNA virus antigenic chimeras. Proc Natl Acad Sci USA 1992, 89:207-211.
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Proc Natl Acad Sci USA
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London, S.D.1
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Dalrymple, J.M.3
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46
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0027192904
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Sindbis virus attachment: Isolation and characterization of mutants with impaired binding to vertebrate cells
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Dubuisson J, Rice CM: Sindbis virus attachment: isolation and characterization of mutants with impaired binding to vertebrate cells. J Virol 1993, 67:3363-3374.
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J Virol
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Dubuisson, J.1
Rice, C.M.2
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