The epidemiology of Alzheimer's disease and vascular dementia in Japanese and African-American populations: The search for etiological clues

Neurobiology of Aging

Volumn 21, Issue 2, 2000, Pages 171-181

  Shadlen, Marie Florence ^a   Larson, Eric B ^a   Yukawa, Michi ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E;

AFRICAN AMERICAN; AGING; ALZHEIMER DISEASE; ASIAN; CEREBROVASCULAR DISEASE; CONFERENCE PAPER; ETHNOLOGY; HUMAN; JAPAN; MULTIINFARCT DEMENTIA; NEGRO; PREVALENCE; PRIORITY JOURNAL; RISK FACTOR; SAMPLING; SOCIAL STATUS; TECHNIQUE;

AFRICAN AMERICANS; AFRICAN CONTINENTAL ANCESTRY GROUP; ALZHEIMER DISEASE; CROSS-CULTURAL COMPARISON; DEMENTIA, VASCULAR; HUMANS; JAPAN; UNITED STATES;

EID: 0034603521     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-4580(00)00115-9     Document Type: Conference Paper

References (161)

1. Arnett D.K., Tyroler H.A., Burke G., et al. Hypertension and subclinical carotid artery atherosclerosis in blacks and whites. The atherosclerosis risk in communities study. Arch Intern Med. 156:1996;1983-1989.
2. Asada T., Yamagata Z., Kinoshita T., Kinoshita A., Kariya T., Asaka A., Kakuma T. Prevalence of dementia and distribution of APOE alleles in Japanese centenerians an almost-complete survey in Yamanashi Prefecture, Japan . J Am Geriatr Soc. 44:1996;151-155.
3. Bachman D.L., Wolf P.A., Linn R.T., Knoefel J.E., Cobb J.L., Belanger A.J., White L.R., D'Agostino R.B. Incidence of dementia and probable Alzheimer's disease in a general population the Framingham Study . Neurology. 43:1993;515-519.
4. Baker F.M. Issues in assessing dementia in African American elders. Yeo G., Gallagher-Thompson D. Ethnicity and the Dementias. 1996;59-71 Taylor & Francis, Washington, DC.
5. Ballard E.L., Nash F., Raiford K., Harrell L.E. Recruitment of African-American elderly for clinical research studies of dementia the CERAD experience . Gerontologist Aug. 33:1993;561-565.
6. Blessed G., Tomlinson B.E., Roth M. The association between quantitative measures of dementia and of senile change in the cerebral gray matter of elderly subjects. Br J Psychiatry. 114:1968;797-811.
7. Bohnstedt M., Fox P., Kohatsu N. Correlates of mini-mental state examination scores among elderly demented patients the influence of race-ethnicity . J of Clin Epidemiology. 47:1994;1381-1387.
8. Brayne C., Calloway P. The association of education and socioeconomic status with the Mini-Mental State Examination and the clinical diagnosis of dementia in elderly people. Age Ageing. 19:1990;91-96.
9. Breteler M.M., Van Swieten J.C., Bots M.L., Grobbee D.E., Claus J.J., van den Hout J.H., van Harskamp F., Tanghe H.L., de Jong P.T., van Gijn J. Cerebral white matter lesions, vascular risk factors, and cognitive function in a population-based study the Rotterdam Study . Neurology. 44:1994;1246-1252.
10. Broderick J., Brott T., Kothari R., et al. The Greater Cincinnati/Northern Kentucky Stroke Study. Preliminary first-ever and total incidence rates of stroke among blacks. Stroke. 29:1998;415-421.
11. Bronner L.L., Kanter D.S., Manson J.E. Medical Progress primary Prevention of Stroke . N Engl J Med. 333:1995;1392-1400.
12. Callahan C.M., Hall K.S., Hui S.L., Musick B.S., Unverzagt F.W., Hendrie H.C. Relationship of age, education, and occupation with dementia among a community-based sample of African Americans. Arch Neurol. 53:1996;134-140.
13. Carmelli D., Swan G.E., Reed T., Wolf P.A., Miller B.L., DeCarli C. Midlife cardiovascular risk factors and brain morphology in identical older male twins. Neurology. 52:1999;1119-1124.
14. Carmelli D., Swan G.E., Reed T., Miller B., Wolf P.A., Jarvik G.P., Schellenberg G.D. Midlife cardiovascular risk factors, APOE, and cognitive decline in elderly male twins. Neurology. 50:1998;1580-1585.
15. Casper M., Wing S., Strogatz D. Variation in the magnitude of black-white differences in stroke mortality in community occupational structure. J Epidemiol Community Health. 45:1991;302-306.
16. Charletta D., Gorelick P.B., Dollear T.J., Freel S., Harris Y. CT and MRI findings among African-Americans with Alzheimer's disease, vascular dementia, and stroke with dementia. Neurology. 45:1995;1456-1461.
17. Chui H.C., Victoroff J.I., Margolin D., et al. Criteria for the diagnosis of ischemic vascular dementia proposed by the State of California Alzheimer's Disease Diagnostic and Treatment Centers. Neurology. 42:1992;473-480.
18. Cooper R., Rotimi C., Ataman S., et al. The prevalence of hypertension in seven populations of West African origin. Am J Public Health. 87:1997;160-168.
19. Cox C., Monk A. Hispanic culture and family care of Alzheimer's patients. Health Social Work. 18:1993;92-100.
20. Cruickshank F.B., Beevers D., Osbourne V., Haynes R., Corlett J., Selby S. Heart attack, stroke, diabetes, and hypertension in West Indians, Asians and Whites in Birmingham, England. BMJ. 281:1980;1108.
21. De la Monte S.M., Hutchins G.M., Moore G.W. Racial differences in the etiology of dementia and frequency of Alzheimer lesions in the brain. J Natl Med Assoc. 81:1989;644-652.
22. Del Ser T., Bermejo F., Portera A., Arredondo J.M., Bouras C., Constantinidis J. Vascular dementia a clinicopathological study . J Neurol Sci. 96:1990;1-17.
23. Diez-Roux A.V., Nieto F.J., Tyroler H.A., Crum L.D., Szklo M. Social inequalities and atherosclerosis the Atherosclerosis Risk in Communities Study . Am J Epidemiol. 141:1995;960-972.
24. Dozono K., Ishii N., Nishihara Y., Horie A. An autopsy study of the incidence of lacunes in relation to age, hypertension, and arteriosclerosis. Stroke. 22:1991;993-996.
25. Duara R., Barker W.W., Lopez A.R., et al. Alzheimer's disease interaction of apolipoprotein E genotype, family history of dementia, gender, education, ethnicity, and age of onset . Neurology. 46:1996;1575-1579.
26. Englund E., Brun A., Gustafson L. A white matter disease in dementia of Alzheimer's type clinical and neuropathological correlates . Int J Ger Psychol. 4:1989;87-102.
27. Erkinjuntti T, Ostbye T, Steenhuis R, Hachinski V. The effect of different diagnostic criteria on the prevalence of dementia. N Engl J Med 1997;337:1667-4.
28. Farrer L.A., Cupples L.A., Haines J.L., et al. Effects of age, sex, and ethnicity in the association between apolipoprotein E genotype and Alzheimer's disease a meta-analysis . J Am Med Assoc. 278:1997;1349-1356.
29. Fillenbaum G., Heyman A., Williams K., Prosnitz B., Burchett B. Sensitivity and specificity of standardized screens of cognitive impairment and dementia among elderly black and white community residents. J Clin Epidemiol. 43:1990;651-660.
30. Fillenbaum G.G., Peterson B., Welsh-Bohmer K.A., Kukull W.A., Heyman A. Progression of Alzheimer's disease in black and white patients the CERAD experience. Part XVI . Neurology. 51:1998;154-158.
31. Folstein M.F., Bassett S.S., Anthony J.C., Romanoski A.J., Nestadt G.R. Dementia. Case ascertainment in a community survey. J Gerontol. 46:1991;M132-M138.
32. Ford G., Haley W., Thrower S., West C.A., Harrell L.E. Utility of Mini-Mental State Exam scores in predicting functional impairment among Caucasian and African-American patients. J Gerontol Series Biol Sci Med Sci. 51:1996;M185-M188.
33. Frisoni G.B., Geroldi C., Bianchetti A., et al. Apolipoprotein E e4 allele frequency in vascular dementia and Alzheimer's disease. Stroke. 25:1994;1703-1704.
34. Gaines K., Burke G. , for the SECORDS Investigators. Ethnic differences in stroke: Black and White differences in the United States population. Neuroepidemiology. 14:1995;209-239.
35. Gearing M., Mirra S.S., Hedreen J.C., Sumi S.M., Hansen L.A., Heyman A. The Consortium To Establish A Registry of Alzheimer's Disease (CERAD), part X neuropathology confirmation of the clinical diagnosis of Alzheimer's disease . Neurology. 45:1995;461-466.
36. Giles W.H., Kittner S.J., Hebel J.R., Losconczy K.G., Sherwin R.V. Determinants of black-white differences in the risk of cerebral infraction National Health and Nutrition Examination Survey Epidemiologic Follow-Up Study . Arch Intern Med. 155:1995;1319-1324.
37. Gillum R.F. The epidemiology of cardiovascular disease in black Americans. N Engl J Med. 335:1996;1597-1598.
38. Gillum R.F., Mussolino M.E., Madans J.H. The relationship between fish consumption and stroke incidence the NHANES I epidemiologic follow-up study . Arch Intern Med. 156:1996;537-542.
39. Gillum R.F. Secular trends in stroke mortality in African Americans the role of urbanization, diabetes, and obesity . Neuroepidemiology. 16:1997;180-184.
40. Gillum R.F. Epidemiology of stroke in blacks. Gillum R.F., Gorelick P.B., Cooper E. Stroke in Blacks. 1999;Karger AG, Basel, Switzerland.
41. Goedert M. Tau protein and the neurofibrillary pathology of Alzheimer's disease. Trends Neurosci. 16:1993;460-465.
42. Gorelick P.B., Chatterjee A., Patel D., Flowerdew G., Dollear W., Taber J., Harris Y. Cranial computed tomographic observations in multi-infarct dementia a controlled study . Stroke. 23:1992;804-811.
43. Gorelick P.B., Brody J., Cohen D.C., Freels S., Levy P., Dollear W., Forman H., Harris Y. Risk factors for dementia associated with multiple cerebral infarcts a case-control analysis in predominantly African-American hospital-based patients . Arch Neurol. 50:1993;714-720.
44. Gorelick P.B., Freels S., Harris Y., Dollear T., Billingsley M., Brown N. Epidemiology of vascular and Alzheimer's dementia among African-Americans in Chicago, Illinois Baseline frequency and comparison of risk factors . Neurology. 44:1994;1391-1396.
45. Gorelick P.B. Stroke prevention windows of opportunity and failed expectations? A discussion of modifiable cardiovascular risk factors and a prevention proposal . Neuroepidemiology. 16:1997;163-173.
46. Gorelick P.B. Cerebrovascular disease in African Americans. Stroke. 29:1998;2656-2664.
47. Graves A.B., Larson E.B., Edland S.D., et al. Prevalence of dementia and its subtypes in the Japanese American population of King County, Washington State. The Kame Project. Am J Epidemiol. 144:1996;760-771.
48. Greenberg S.M., Rebeck G.W., Vonsattel J.P.G., et al. Apolipoprotein E epsilon 4 and cerebral hemorrhage associated with amyloid angiopathy. Ann Neurol. 38:1995;254-259.
49. Gross C., Kase C., Mohr J., et al. Stroke in South Alabama incidence and diagnostic features in a population-based study . Stroke. 15:1984;249-254.
50. Guralnik J.M., Leveille S.G. Race, ethnicity, and health outcomes unraveling the mediating role of socioeconomic status . Am J Public Health. 87:(5):1997;728-730.
51. Haan J. Amyloid in central nervous system disease. Clin Neurol Neurosurg. 92:1990;305-310.
52. Hachinski V.C. Preventable senility a call for action against the vascular dementias . Lancet. 340:1992;645-648.
53. Hachinski V.C. Vascular dementia a radical redefinition . Dementia. 5:1994;130-132.
54. Haley W.E., West C.A., Wadley V.G., et al. Psychosocial, social, and health impact of caregiving a comparison of Black and dementia family caregivers and non-caregivers . Psychol Aging. 10:1995;540-552.
55. Hall K.S., Ogunniyi A.O., Hendrie H.C., et al. A cross-cultural community-based study of dementias methods and performance of the survey instrument in Indianapolis, USA, and Ibadan, Nigeria . Intl J Methods Psychiatric Res. 6:1996;129-142.
56. Hallman D.M., Boerwinkle E., Saha N., et al. The apolipoprotein E polymorphism a comparison of allele frequencies and effects in nine populations . Am J Hum Genet. 49:1991;338-349.
57. Hardy J., Duff K., Hardy K., Perez-Tur J., Hutton M. Genetic dissection of Alzheimer's disease and related dementias amyloid and the importance of tau. Nat Neurosci. 1:1998;355-358.
58. Hendrie H.C., Osuntokun B.O., Hall K.S., et al. Prevalence of Alzheimer's disease and dementia in two communities Nigerian Africans and African Americans . Am J Psychiatry. 152:1995;1485-1492.
59. Hendrie H.C., Hall K.S., Hui S., et al. Apolipoprotein E genotypes and Alzheimer's disease in a community study of elderly African Americans. Ann Neurol. 37:1995;118-120.
60. Heyman A., Fillenbaum G., Prosnitz B., Raiford K., Burchett B., Clark C. Estimated prevalence of dementia among elderly Black and White community residents. Arch Neurol. 48:1991;594-598.
61. Heyman A., Peterson B., Fillenbaum G., Pieper C. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part XIV: Demographic and clinical predictors of survival in patients with Alzheimer's disease . Neurology. 46:1996;656-660.
62. Higuchi S., Arai H., Nakagawa T., Muramatsu T., Sasaki H., Trojanowski J.Q. The apolipoprotein E gene in Binswanger's disease and vascular dementia. Clin Genet. 50:1996;459-461.
63. Hobbs FB, Damon DL. 65+ in the United States. Washington, DC: Bureau of the Census 1996;Publication P23-190.
64. Howard G., Anderson R., Sorlie P., Andrews V., Backlund E., Burke G.L. Ethnic differences in stroke mortality between non-Hispanic whites, Hispanic Whites, and Blacks. Natl Longitudinal Mortality Study Stroke. 25:1994;2120-2125.
65. Howard G., Russell G.B., Anderson R., Evans G.W., Morgan T., Howard V.J. Role of social class in excess black stroke mortality. Stroke. 26:1995;1759-1763.
66. Hulette C., Nochlin D., McKeel D., Morris J.C., Mirra S.S., Sumi S.M., Heyman A. Clinical-neuropathologic findings in multi-infarct dementia a report of six autopsied cases . Neurology. 48:1997;668-672.
67. Iso H., Shimamoto T., Naito Y., Sato S., Kitamura A., Iida M., Konishi M., Jacobs D.R., Komachi Y. Effects of a long-term hypertension control program on stroke incidence and prevalence in a rural community in northeastern Japan. Stroke. 29:1998;1510-1518.
68. Jorm A.F., Jolley D. The incidence of dementia a meta-analysis . Neurology. 51:1998;728-733.
69. Kamboh M.I., Sepehrnia B., Ferrell R.E. Genetic studies of human apolipoproteins, VI common polymorphism of apolipoprotein E in blacks . Dis Markers. 7:1989;49-55.
70. Kawamata J., Tanaka S., Shimohama S., Ueda K., Kimura J. Apolipoprotein E polymorphism in Japanese patients with Alzheimer's disease or vascular dementia. J Neurol Neurosurg and Psychiatr. 57:1994;1414-1416.
71. Kittner S., White L., Losonczy K., Wolf P.A., Hebel J.R. Black-white differences in stroke incidence in a national sample the contribution of hypertension and diabetes mellitus . J Am Med Assoc. 264:1990;1267-1270.
72. Kiyohara Y., Yoshitake T., Kato I., Ohmura T., Kawano H., Ueda K., Fujishima M. Changing patterns in the prevalence of dementia in a Japanese community the Hisayama study . Gerontology. 40:(suppl 2):1994;29-35.
73. Klatka L.A., Schiffer R.B., Powers J.M., Kazee A.M. Incorrect diagnosis of Alzheimer's disease a clinicopathologic study . Arch Neurol. 53:1997;35-42.
74. Kokmen E., Whisnant J.P., O'Fallon W.M., Chu C.-P., Beard C.M. Dementia after ischemic stroke a population-based study in Rochester, Minnesota (1960-1984) . Neurology. 46:1996;154-159.
75. Komahashi T., Ohmori K., Nakano T., et al. Epidemiological survey of dementia and depression among the aged living in the community in Japan. Jpn J Psychiatry Neurol. 48:1994;517-526.
76. Kondo K., Niino M., Shido K. A case-control study of Alzheimer's disease in Japan- significance of life-styles. Dementia. 5:1994;314-326.
77. Kukull W.A., Martin G.M. APOE Polymorphisms and late-onset Alzheimer disease the importance of ethnicity . (Editorial) J Am Med Assoc. 279:1998;788-789.
78. Kuller L.H., Shemanski L., Manolio T., et al. Relationship of APOE, MRI abnormalities and cognitive function in the Cardiovascular Health Study. Stroke. 29:1998;388-398.
79. Launer L.J., Masaki K., Petrovitch H., et al. The association between midlife blood pressure levels and late-life cognitive function the Honolulu-Asia Aging Study . J Am Med Assoc. 274:1995;1846-1851.
80. Landen M., Thorsell A., Wallin A., Blennow K. The apolipoprotein E allele epsilon 4 does not correlate with the number of senile plaques or neurofibrillary tangles in patients with Alzheimer's disease. J Neurol Neurosurg Psychiatry. 61:1996;352-356.
81. Leon J., Lair T. Functional status of the noninstitutionalized elderly estimates of ADL and IADL difficulties . 1990;Agency for Health Care Policy and Research, Rockville.
82. Liao D., Cooper L., Cai J., et al. The prevalence and severity of white matter lesions, their relationship with age, ethnicity, gender, and cardiovascular risk factors the ARIC Study . Neuroepidemiol. 16:1997;149-162.
83. Lim A., Tsuan D., Kukull W., et al. Clinico-Neuropathological correlation of Alzheimer's disease in a community-based case series. J Am Ger Soc. 47:1999;564-569.
84. Lopez O.L., Larumbe M.R., Becker J.T., et al. Reliability of NINDS-AIREN clinical criteria for the diagnosis of vascular dementia. Neurology. 44:1994;1240-1245.
85. Lum O.M. Health status of Asians and Pacific Islanders. Clin Geriatr Med. 11:1995;53-67.
86. Maestre G., Ottman R., Stern Y., et al. Apolipoprotein E, and Alzheimer's disease ethnic variation in genotype risk . Ann Neurol. 37:1995;254-259.
87. Manolio T.A., Burke G.L., Psaty B.M., et al. Black-white differences in subclinical disease among older adults the Cardiovascular Health Study . J Clin Epidemiol. 48:1995;1141-1152.
88. Martin G.M., Kukull W.A. Do cultural differences affect Alzheimer's disease? (Editorial; comment) J Am Med Assoc. 276:1996;955-960.
89. Masuda J., Tanaka K., Ueda K., Omae T. Autopsy study of incidence and distribution of dementia in Hisayama, Japan. Stroke. 19:1988;205-210.
90. Mayeux R., Stern Y., Ottman R., et al. The apolipoprotein epsilon 4 allele in patients with Alzheimer's disease. Ann Neurol. 34:1993;752-754.
91. McKhann G., Drachman D., Folstein M., Katzman R., Price D., Stadlan E.M. Clinical diagnosis of Alzheimer's disease report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services task force on Alzheimer's disease . Neurology. 34:1984;933-944.
92. Meyer J.S., Judd B.W., Tawakina T., Rogers R.L., Mortel K.F. Improved cognition after control of risk factors for multi-infarct dementia. J Am Med Assoc. 256:1986;2203-2209.
93. Miyao S., Takano A., Teramoto J., Takahashi A. Leukoaraiosis in relation to prognosis for patients with lacunar infarction. Stroke. 23:1992;1434-1438.
94. Molgaard C.A., Stanford E.P., Morton D.J., Ryden L.A., Schubert K.R., Goldbeck A.L. Epidemiology of head trauma and neurocognitive impairment in a multi-ethnic population. Neuroepidemiology. 9:1990;233-242.
95. Moroney J.T., Bagiella E., Desmond D.W., et al. Meta-analysis of the Hachinski Ischemic Score in pathologically verified dementias. Neurology. 49:1997;1096-1105.
96. Moroney J.T., Tang M.X., Berglund L., et al. Low-density lipoprotein cholesterol and the risk of dementia with stroke. J Am Med Assoc. 282:1999;254-260.
97. Mortel K.F., Meyer J.S., Herod B., Thornby J. Education and occupation as risk factors for dementias of the Alzheimer and ischemic vascular type. Dementia. 6:1995;55-62.
98. Murden R., McRae T., Kaner S., Bucknam M. Mini-mental state exam scores vary with education in blacks and whites. J Am Geriatr Soc. 39:1991;149-155.
99. Myers R.H., Schaefer E.J., Wilson P.W.F., et al. Apolipoprotein E allele 4 is associated with dementia in a population-based study the Framingham Study . Neurology. 46:1996;673-677.
100. National Center for Health Statistics. Health, United States - 1997, and Injury Chartbook. Hyattsville, MD: US Department of Health and Human Services; 1996:1997.
101. National Institute of Aging. Comments on the GAO Report: Alzheimer's Disease Estimates of Prevalence in the United States. United States General Accounting Office (1998) Alzheimer's Disease: estimates of prevalence in the United States. GAO Report #HEHS-98-16, January: 38-42.
102. Nunomura A., Chiba S., Eto M., Saito M., Makino I., Miyagishi T. Apolipoprotein E polymorphism and susceptibility to early and late-onset sporadic Alzheimer's disease in Hokkaido, the northern part of Japan. Neurosci Lett. 206:1996;17-20.
103. Nyenhuis D.L., Gorelick P.B. Vascular dementia a contemporary review of epidemiology, diagnosis, prevention, and treatment . J Am Geriatr Soc. 46:1998;1437-1448.
104. Okada H., Horibe H., Yoshiyuki O., Hayakawa N., Aoki N. A prospective study of cerebrovascular disease in Japanese rural communities, Akabane and Asahi. Part I: evaluation of risk factors in the occurrence of cerebral hemorrhage and thrombosis . Stroke. 7:1976;599-607.
105. Okumiya K., Matsubayashi K., Wada T., et al. J-curve relation between blood pressure and decline in cognitive function in older people living in the community, Japan. (letter) Lancet. 45:1997;1032-1033.
106. Olichney J.M., Hansen L.A., Hofstetter C.R., Grundman M., Katzman R., Thal L.J. Cerebral infarction in Alzheimer's disease is associated with severe amyloid angiopathy and hypertension. Arch Neurol. 52:1995;702-708.
107. Olsson Y., Brun A., Englund E. Fundamental pathological lesions in vascular dementia. Acta Neurol Scand. 168:(suppl):1996;31-38.
108. Osuntokun B.O., Sahota A., Ogunniyi A.O., et al. Lack of an association between apolipoprotein E e4 and Alzheimer's disease in elderly Nigerians. Ann Neurol. 38:1995;463-465.
109. Ott A., Breteler M.M.B., Van Harskamp F., et al. Prevalence of Alzheimer's disease and vascular dementia association with education: the Rotterdam study . BMJ. 310:1995;970-973.
110. Otten M., Teutschs, Williamson D., Marks J. The effect of known risk factors on the excess mortality of black adults in the United States. J Am Med Assoc. 263:1990;845-850.
111. Palumbo B., Parnetti L., Nocentini G., et al. Apolipoprotein-E genotype in normal aging, age-associated memory impairment, Alzheimer's disease and vascular dementia patients. Neurosci Lett. 231:1997;59-61.
112. Perkins P., Annegers J.F., Doody R.S., Cooke N., Aday L., Vernon S.W. Incidence and prevalence of dementia in a multiethnic cohort of municipal retirees. Neurology. 49:1997;44-50.
113. Pickle L.W., Mungiole M., Gillum R.F. Geographic variation in stroke mortality in blacks and whites in the United States. Stroke. 28:1997;1639-1647.
114. Pirttila T., Lehtimaki T., Rinne J., Mattila K., Frey H., Nikkari T. The frequency of apolipoprotein E4 allele is not increased in patients with probable vascular dementias. Acta Neurol Scand. 93:1996;352-354.
115. Plassman B.L., Breitner J.C.S. Recent advances in the genetics of Alzheimer's disease and vascular dementia with an emphasis on gene-environment interactions. J Am Geriatr Soc. 44:1996;1242-1250.
116. Pullicino P., Benedict R.H., Capruso D.X., Vella N., Withiam-Leitch S., Kwen P.L. Neuroimaging criteria for vascular dementia. Arch Neurol. 53:1996;723-728.
117. Qureshi A.I., Giles W.H., Croft J.B. Racial differences in the incidence of intracerebral hemorrhage effects of blood pressure and education . Neurology. 52:1999;1617-1621.
118. Reed D, Jacobs DR, Hayashi T, Konishi M, Nelson J, Iso H, Strong J. A comparison of lesions in small intracerebral arteries among Japanese men in Hawaii and Japan. Stroke 1994:60-5.
119. Richey P.L., Siedlak S.L., Smith M.A., Perry G. Apolipoprotein E interaction with the neurofibrillary tangles and senile plaques in Alzheimer disease implications for disease pathogenesis . Biochem Biophys Res Commun. 208:1995;657-663.
120. Roman G.C., Tatemichi T.K., Erkinjuntti T., et al. Vascular dementia diagnostic criteria for research studies: report of the NINDS-AIREN international workshop . Neurology. 43:1993;250-260.
121. Ross G.W., Abbott R.D., Petrovitch H., et al. Frequency and characteristics of silent dementia among elderly Japanese-American men the Honolulu-Asia Aging Study . J Am Med Assoc. 277:1997;800-805.
122. Ross G.W., Petrovitch H., White L.R., et al. Characterization of risk factors for vascular dementia The Honolulu-Asia Aging Study . Neurology. 53:1999;337-343.
123. Sacco R.L., Kargman D.E., Zamanillo M.C. Race-ethnic differences in stroke risk factors among hospitalized patients with cerebral infarction the Northern Manhattan Stroke Study . Neurology. 45:1995;659-663.
124. Sacco RL, Boden-Albala B, Gan R, Chen Y, Kargman DE, She MC, Hauser WA, for the Northern Manhattan Stroke Study. Stroke incidence among White, Black and Hispanic residents of an urban Community. The Northern Manhattan stroke study. Am J Epidemiol 1998;263:845-50.
125. Sandholzer C., Delport R., Vermnaak H., Utermann G. High frequency of the apolipoprotein epsilon 4 allele in Khoi San from South Africa. Human Genet. 95:1995;46-48.
126. Schoenberg B.S., Anderson O.W., Haerer A.I. Severe dementia prevalence and clinical features in a biracial U.S. population . Arch Neurol. 42:1985;740-743.
127. Sepehrnia B., Kamboh M.I., Adams-Campbell L.L., Nwankwo M., Ferrell R.E. Genetic studies of human apolipoprotein, X the effect of apolipoprotein E polymorphism on quantitative levels of lipoproteins in Nigerian blacks . Am J Human Genet. 45:1989;586-591.
128. Shadlen M.F. Effects of age and ethnicity on the link between APOE epsilon 4 and Alzheimer disease. (letter; comment) J Am Med Assoc. 279:1998;581.
129. Shadlen M.F., Larson E.B., Gibbons L., McCormick W.C., Teri L. Alzheimer's disease symptom severity in Blacks and Whites. J Am Geriatr Soc. 47:1999;482-486.
130. Skoog I., Lemfelt B., Landahl S., et al. 15-year longitudinal study of blood pressure and dementia. Lancet. 347:1996;1141-1145.
131. Slooter A.J.C., Tang M.-X., van Duijn C.M., et al. Apolipoprotein E epsilon 4 and the risk of dementia with stroke a population-based investigation . J Am Med Assoc. 277:1997;818-821.
132. Snowdon D.A., Greiner L.H., Mortimer J.A., Riley K.P., Greiner P.A., Markesbery W.R. Brain infarction and the clinical expression of Alzheimer's disease the Nun Study . J Am Med Assoc. 277:1997;813-817.
133. Stanford E.P., Dubois B. Alzheimer's disease and related disorders among African-Americans. Molgaard C. Neuroepidemiology, Theory, and Method. 1993;195-210 Academic Press, Inc, New York.
134. Starkstein S.E., Sabe L., Vasquez S., et al. Neuropsychological, psychiatric, and cerebral blood flow findings in vascular dementia and Alzheimer's disease. Stroke. 27:1996;408-414.
135. Stern Y., Gurland B., Tatemichi T.K., Tang M.X., Wilder D., Mayeux R. Influence of education and occupation on the incidence of Alzheimer's disease. J Am Med Assoc. 271:1994;1004-1010.
136. Stewart J.A., Dundas R., Howard R.S., Rudd A.G., Wolfe C.D.A. Ethnic differences in incidence of stroke prospective study with stroke register . BMJ. 30:(8):1999;1740.
137. Sulkava R., Kainulainen K., Verkkoniemi A., et al. APOE alleles in Alzheimer's disease and vascular dementia in a population aged 85+. Neurobiol Aging. 17:1996;373-376.
138. Suzuki K., Kutsuzawa T., Takita K., et al. Clinico-epidemiologic study of stroke in Akita, Japan. Stroke. 18:1987;402-406.
139. Suzuki N., Iwatsubo T., Odaka A., Ishibashi Y., Kitada C., Ihara Y. High tissue content of soluble B1-40 is linked to cerebral amyloid angiopathy. Am J Pathol. 145:1994;452-460.
140. Tanaka H., Tanaka Y., Hayashi M., et al. Secular trends in mortality for cerebrovascular diseases in Japan, 1960 to 1979. Stroke. 13:1982;574-581.
141. Tang M.X., Maestre G., Tsai W.Y., et al. Relative risk of Alzheimer's disease and age-at-onset based on APOE genotypes among elderly African Americans, Caucasians and Hispanics in New York City. Am J Human Genet. 58:1996;574-584.
142. Tang M.X., Stern Y., Marker K., et al. The APOE-epsilon 4 allele and the risk of Alzheimer's Disease among African Americans, whites, and Hispanics. J Am Med Assoc. 279:1998;751-755.
143. Tatemichi T.K., Desmond D.W., Mayeux R., et al. Dementia after stroke baseline frequency, risks, and clinical features in a hospitalized cohort . Neurology. 42:1992;1185-1193.
144. Tatemichi T.K., Paik M., Bagiella E., et al. Risk of dementia after stroke in a hospitalized cohort results of a longitudinal study . Neurology. 44:1994;1885-1891.
145. Thomas T., Thomas G., McLendon C., Sutton T., Mullan M. B-amyloid-mediated vasoactivity and vascular endothelial damage. Nature. 380:1996;168-171.
146. Thorvaldsen P., Asplund K., Kuulasmaa K., Rajakangas A., Schroll M. Stroke incidence, case fatality and mortality in the WHO MONICA project. Stroke. 26:1995;361-367.
147. Tsuang D., Kukull W., Sheppard L., Barnhart R.L., Peskind E., Edland S.D., Schellenberg G., Raskind M., Larson E.B. Impact of sample selection on apolipoprotein E epsilon 4 allele frequency a comparison of two Alzheimer's disease samples . J Am Geriatr Soc. 44:1996;704-707.
148. Tuszynski M.H., Petito C.K., Levy D.E. Risk factors and clinical manifestations of pathologically verified lacunar infarctions. Stroke. 20:1989;990-999.
149. Ueda K., Hasuo Y., Fujishima M. Prevalence and etiology of dementia in a Japanese community. Stroke. 23:1992;798-803.
150. United States Bureau of the Census, 1989. Preliminary estimates of the population of the U.S, by age, sex, and race. Current population reports series P-25, No. 1018, Table 4, middle series.
151. United States Bureau of the Census. Economics and Statistics Administration, Department of Commerce 1993; Racial and Ethnic Diversity in America's Population:11:1-8.
152. United States General Accounting Office. Alzheimer's Disease. Estimates of prevalence in the United States. GAO Report 1998 #HEHS-98-16;January:.
153. Unverzagt F.W., Hall K.S., Torke A.M., et al. Effects of age, education, and gender on CERAD Neuropsychological test performance in an African American sample. Clin Neuropsychol. 10:1996;180-190.
154. Wallin A., Blennow K. Heterogeneity of vascular dementia mechanisms and subgroups . J Geriatr Psychiatry Neurol. 6:1993;177-188.
155. Welsh K., Fillenbaum G., Wilkinson W., et al. Neuropsychological test performance in African-American and Caucasian patients with Alzheimer's disease. Neurology. 45:1995;2207-2211.
156. Wang K. Studies of human apolipoprotein E genetic isoform and their phenotype among the Chinese population. Acta Acad Med Sinicae. 8:1986;192-198.
157. Welsh K.A., Ballard E., Nash F., Raiford K., Harrell L. Issues affecting minority participation in aging research studies of Alzheimer's disease. Alzheimer's Dis Assoc Disord. 8:(suppl 4):1994;38-48.
158. White L., Petrovitch H., Ross G.W., et al. Prevalence of dementia in older Japanese-American men in Hawaii The Honolulu-Asia Aging Study . J Am Med Assoc. 276:1996;955-960.
159. Yamada M., Sasaki H., Mimori Y., et al. Prevalence and risks of dementia in the Japanese population RERF's Adult Health Study Hiroshima subjects . J Am Geriatr Soc. 47:1999;189-195.
160. Yeo G., Gallagher-Thompson D., Lieberman M. Variations in dementia characteristics by ethnic category. Yeo G., Gallagher-Thompson D. Ethnicity and the Dementias. 1996;21-30 Taylor and Francis, Washington, DC.
161. Yoshitake T., Kiyohara Y., Kato I., et al. Incidence and risk factors of vascular dementia and Alzheimer's disease in a defined elderly Japanese population the Hisayama Study . Neurology. 45:1995;1161-1168.