APOE alleles in Alzheimer's disease and vascular dementia in a population aged 85+

Neurobiology of Aging

Volumn 17, Issue 3, 1996, Pages 373-376

  Sulkava, Raimo ^a   Kainulainen, Kati ^d   Verkkoniemi, Auli ^d   Niinistö, Leena ^b   Sobel, Eugene ^c   Davanipour, Zoreh ^c   Polvikoski, Tuomo ^d   Haltia, Matti ^d   Kontula, Kimmo ^d  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b Katriina Geriatric Hospital   (Finland)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^d Box 1627 ^*

Author keywords

Alzheimer's disease; apolipoprotein E; epidemiology; risk factor; vascular dementia; very old

Indexed keywords

APOLIPOPROTEIN E;

AGED; AGING; ALLELE; ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; DEMENTIA; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RISK FACTOR;

EID: 0029942993     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/0197-4580(96)00023-1     Document Type: Article

References (32)

1. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. Third edition - revised. DSM-III-R, Washington, DC: American Psychiatric Association; 1987.
2. Corder, E. H.; Saunders, A. M.; Strittmatter, W. J.; Schmechel, D. E.; Gaskell, P. C.; Small, G. W.; Roses, A. D.; Haines, J. L.; Pericak-Vance, M. A. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 261:921-923: 1993.
3. Davignon, J.; Gregg, R. E.; Sing, C. F. Apolipoprotein E polymorphism and atherosclerosis. Atherosclerosis 8:1-21; 1988.
4. Ehnholm, C.; Lukka, M.; Kuusi T.; Nikkilä, E.; Utermann, G. Apolipoprotein polymorphism in the Finnish population: Gene frequencies and ratio to lipoprotein concentrations. J. Lipid Res. 27:227-235; 1986.
5. Hixson, J. E.; PDAY Research Group. Apolipoprotein E polymorphisms affect atherosclerosis in young males. Arterioscler. Thromb. 11:1237-1244; 1991.
6. Kuusisto, J.; Koivisto, K.; Kervinen, K.; Mykkänen, L.; Helkala, E.-L.; Vanhanen, M.; Hänninen, T.; Pyörälä, K.; Kesäniemi, Y. A.; Riekkinen, P.; Laakso, M. Association of apolipoprotein E phenotypes with late onset Alzheimer's disease: Population based study. Br. Med. J. 309:636-638; 1994.
7. Lehtimäki, T.; Moilanen, T.; Viikari, J.; Åkerblom, H. K.; Ehnholm, C.; Rönnemaa, T.; Marniemi, J.; Dahlen, G.; Nikkari, T. Apolipoprotein E phenotypes in Finnish youths: A cross-sectional and 6-year follow-up study. J. Lipid Res. 31:487-495; 1990.
8. Louhija, J.; Miettinen, H. E.; Kontula, K. Aging and genetic variation of plasma apolipoproteins: Relative loss of the apolipoprotein E4 phenotype in centenarians. Arterioscler. Thromb. 14:1084-1089; 1994.
9. Mahley, R. W. Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology. Science 240:622-630; 1988.
10. Mayeux, R.; Stern, Y.; Ottman, R.; Tatemichi, T. K.; Tang, M-X.; Maestre, G.; Ngai, C.; Tycko, B; Ginsberg, H. The apolipoprotein ∈4 allele in patients with Alzheimer's disease. Ann. Neurol. 34:752-754; 1993.
11. McKhann, G.; Drachman, D.; Folstein, M.; Katzman, R.; Price, D.; Stadlan, E. Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of department of health and human services task force on Alzheimer's disease. Neurology 34:939-944; 1984.
12. Namba, Y.; Tomonaga, M.; Kawasaki, H.; Otomo, E.; Ikeda, K. Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease. Brain Res. 541:163-166; 1991.
13. Noguchi, S.; Murakami, K.; Yamada, N. Apolipoprotein E genotype and Alzheimer's disease. Lancet 342:737; 1993.
14. Pericak-Vance, M. A.; Bebout, J. L.; Gaskell, P. C., Jr.; Yamaoka, L. H.; Hung, W. Y.; Alberts, M. J.; Walker, A. P.; Barlett, R. J.; Haynes, C. A.; Wesh, K. A.; Earl, N. L.; Heyman, A.; Clark, C. M.; Roses, A. D. Linkage studies in familial Alzheimer's disease: Evidence for chromosome 19 linkage. Am. J. Hum. Genet. 48:1034-1050; 1991.
15. Poirier, J.; Davignon, J.; Bouthillier, D.; Kogan, S.; Bertrand, P.; Gauthier, S. Apolipoprotein E polymorphism and Alzheimer's disease. Lancet 342:697-699; 1993.
16. Rebeck, G. W.; Reiter, J. S.; Strickland, D. K.; Hyman, B. T. Apolipoprotein E in sporadic Alzheimer's disease: Allelic variation and receptor interactions. Neuron 11:575-580; 1993.
17. Roman, G. C.; Tatemichi, T. K.; Erkinjuntti, T.; Cummings, J. L.; Mahdeu, J. C.; Garcia, J. H.; et.al. Vascular dementia: Diagnostic criteria for research studies. Report of the NINCDS-AIREN International Work Group. Neurology 43:250-260; 1993.
18. Saunders, A. M.; Schmader, K.; Breitner; J. C. S.; Benson, M. D.; Brown, W. T.; Goldfarb, L.; et.al. Apolipoprotein E e4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases. Lancet 342:710-711; 1993.
19. Saunders, A. M.; Strittmatter, W. J.; Schmechel, D.; St. George-Hyslop, P. H.; Pericak-Vance, M. A.; Joo, S. H.; Rosi, B. L; Gusella, J. F.; Crapper-MacLachlan, D. R.; Alberts, M. J.; Hulette, C.; Crain, B.; Goldgaber, D.; Roses, A. D. Association of apolipoprotein E allele 4 with late-onset familial and sporadic Alzheimer's disease. Neurology 43:1467-1472; 1993.
20. Schmechel, D. E.; Saunders, A. M.; Strittmatter, W. J.; Crain, B. J.; Hulette, C. M.; Joo, S. H.; Pericak-Vance, M. A.; Goldgaber, D.; Roses, A. D. Increased amyloid β-peptide deposition in cerebralcortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease. Proc. Natl. Acad. Sci. USA 90:9649-9653; 1993.
21. Sherrington, R.; Rogaev, E. I.; Liang, Y.; et al. Cloning of a gene bearing missense mutations in early onset familial Alzheimer's disease. Nature 375:754-760; 1995.
22. Skoog, I.; Nilsson, L.; Palmertz, L.-A.; Andreasson, L. A.; Svanborg, A. A population based study of dementia in 85-year-olds. N. Engl. J. Med. 328;153-158;1993.
23. Sobel, E.; Louhija, J.; Sulkava, R.; Davanipour, Z.; Kontula, K.; Miettinen, H.; Tikkanen, M.; Kainulainen, K.; Tilvis, R. Lack of association of apolipoprotein E allele e4 with late-onset Alzheimer's disease among Finnish centenarians. Neurology 45:903-907; 1995.
24. Strittmatter, W. J.; Saunders, A. M.; Schmechel, D.; Pericak-Vance, M.; Enghild, J.; Salvesen, G. S.; Roses, A. D. Apolipoprotein E: High avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer's disease. Proc. Natl. Acad. Sci. USA 90:1977-1981; 1993.
25. Strittmatter, W. J.; Weisgraber, K. H.; Huang, D. Y.; Salvesen, G. S.; Pericak-Vance, M.; et. al. Binding of human apolipoprotein E to synthetic amyloid β peptide: Isoform-specific effects and implications for late-onset Alzheimer disease. Proc. Natl. Acad. Sci. USA 90:8098-8102; 1993.
26. Syvänen, A.-C.; Aalto-Setälä, K.; Harju, L.; Kontula, K.; Söderlund, H. A primer-guided nucleotide incorporation assay in the genotyping of apolipoprotein E. Genomics 8:684-692; 1990.
27. Syvänen, A.-C.; Sajantila, A.; Lukka, M. Identification of individuals by analysis of biallelic DNA markers using PCR and solid-phase minisequencing. Am. J. Hum. Genet. 52:46-59; 1993.
28. Uterman, G. Apolipoprotein E polymorphism in health and disease. Am. Heart J. 113:433-440; 1987.
29. van Duijn, C. M.; de Knijff, P.; Cruts, M.; Wehnert, A.; Havekes, L. M.; Hofman, A.; van Broeckhoven, C. Apolipoprotein E4 allele in a population-based study of early onset Alzheimer's disease. Nat. Genet. 7:74-78; 1994.
30. Weisgraber, K. H.; Roses, A. D.; Strittmatter, W. J. The role of apolipoprotein E in the nervous system. Curr. Opin. Lipidol. 5:110-116; 1994.
31. Wisniewski, T.; Frangione, B. Apolipoprotein E: A pathologic chaperone protein in patients with cerebral and systemic amyloid. Neurosci. Lett. 135:235-238; 1992.
32. Wisniewski, T.; Golabek, A.; Matsubara, E.; Ghiso, J.; Frangione, B., Apolipoprotein E: Binding to soluble Alzheimer's β-amyloid. Biochem. Biophys. Res. Commun. 192:359-365; 1993.