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Volumn 44, Issue 10, 1996, Pages 1242-1250

Recent advances in the genetics of Alzheimer's disease and vascular dementia with an emphasis on gene-environment interactions

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; APOLIPOPROTEIN E; GENE PRODUCT; PROTEIN PRECURSOR;

EID: 0029840047     PISSN: 00028614     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1532-5415.1996.tb01377.x     Document Type: Article
Times cited : (49)

References (150)
  • 1
    • 0021875526 scopus 로고
    • Prevalence of severe dementia in Finland
    • Sulkava R, Wikstrom J, Aromaa A et al. Prevalence of severe dementia in Finland. Neurology 1985;35:1025-1029.
    • (1985) Neurology , vol.35 , pp. 1025-1029
    • Sulkava, R.1    Wikstrom, J.2    Aromaa, A.3
  • 2
    • 0025306076 scopus 로고
    • The prevalence of dementia and Alzheimer's disease in Shanghai, China: Impact of age, gender, and education
    • Zhang MY, Katzman R, Salmon D et al. The prevalence of dementia and Alzheimer's disease in Shanghai, China: Impact of age, gender, and education. Ann Neurol 1990;27:428-437.
    • (1990) Ann Neurol , vol.27 , pp. 428-437
    • Zhang, M.Y.1    Katzman, R.2    Salmon, D.3
  • 3
    • 0025273369 scopus 로고
    • Prevalence of clinically diagnosed Alzheimer's disease and other dementing disorders: A door-to-door survey in Appignano, Macerata Province, Italy
    • Rocca WA, Bonaiuto S, Lippi A et al. Prevalence of clinically diagnosed Alzheimer's disease and other dementing disorders: A door-to-door survey in Appignano, Macerata Province, Italy. Neurology 1990;40:626-631.
    • (1990) Neurology , vol.40 , pp. 626-631
    • Rocca, W.A.1    Bonaiuto, S.2    Lippi, A.3
  • 4
    • 0014851803 scopus 로고
    • Observations on the brains of demented old people
    • Tomlinson BE, Blessed G, Roth M. Observations on the brains of demented old people. J Neurol Sci 1970;11:205-242.
    • (1970) J Neurol Sci , vol.11 , pp. 205-242
    • Tomlinson, B.E.1    Blessed, G.2    Roth, M.3
  • 5
    • 0017155472 scopus 로고
    • Neuropathological aspects of dementias resulting from abnormal blood and cerebrospinal fluid dynamics
    • Jellinger K. Neuropathological aspects of dementias resulting from abnormal blood and cerebrospinal fluid dynamics. Acta Neurol Belg 1976;76:83-102.
    • (1976) Acta Neurol Belg , vol.76 , pp. 83-102
    • Jellinger, K.1
  • 6
    • 0025262350 scopus 로고
    • Clinicopathological analysis of dementia disorders in the elderly
    • Jellinger K, Danielczyk W, Fischer P, Gabriel E. Clinicopathological analysis of dementia disorders in the elderly. J Neurol Sci 1990;95:239-258.
    • (1990) J Neurol Sci , vol.95 , pp. 239-258
    • Jellinger, K.1    Danielczyk, W.2    Fischer, P.3    Gabriel, E.4
  • 7
    • 0002445407 scopus 로고
    • The Lund Longitudinal Dementia Study: A 25-year perspective on neuropathology, differential diagnosis and treatment
    • Corain B, Iqbal K, Nicolini M, Winblad B, Wisniewski H, Zatta P, eds. New York: John Wiley & Sons
    • Brun A, Gustafson L. The Lund Longitudinal Dementia Study: A 25-year perspective on neuropathology, differential diagnosis and treatment. In: Corain B, Iqbal K, Nicolini M, Winblad B, Wisniewski H, Zatta P, eds. Alzheimer's Disease: Advances in Clinical and Basic Research. New York: John Wiley & Sons, 1993, pp 3-18.
    • (1993) Alzheimer's Disease: Advances in Clinical and Basic Research , pp. 3-18
    • Brun, A.1    Gustafson, L.2
  • 8
    • 0002479711 scopus 로고
    • A genetic study of morbus Alzheimer and morbus Pick
    • Sjogren T. A genetic study of morbus Alzheimer and morbus Pick. Acta Psychiatry Neurol Scand 1952;82(suppl):9-63.
    • (1952) Acta Psychiatry Neurol Scand , vol.82 , Issue.SUPPL. , pp. 9-63
    • Sjogren, T.1
  • 9
    • 0002487699 scopus 로고
    • Senile dementia. A clinical, sociomedical and genetic study
    • Larsson T, Sjogren T, Jacobson G. Senile dementia. A clinical, sociomedical and genetic study. Acta Psychiatr Scand 1963;39(suppl 167): 1-259.
    • (1963) Acta Psychiatr Scand , vol.39 , Issue.167 SUPPL. , pp. 1-259
    • Larsson, T.1    Sjogren, T.2    Jacobson, G.3
  • 10
    • 0019402114 scopus 로고
    • Dementia of the Alzheimer type: Clinical genetics, natural history and associated conditions
    • Heston LL, Mastri AR, Anderson VE, White J. Dementia of the Alzheimer type: Clinical genetics, natural history and associated conditions. Arch Gen Psychiatry 1981;38:1085-1090.
    • (1981) Arch Gen Psychiatry , vol.38 , pp. 1085-1090
    • Heston, L.L.1    Mastri, A.R.2    Anderson, V.E.3    White, J.4
  • 11
    • 0021194571 scopus 로고
    • Familial Alzheimer dementia: A prevalent disorder with specific, clinical features
    • Breitner JCS, Folstein MF. Familial Alzheimer dementia: A prevalent disorder with specific, clinical features. Psychol Med 1984;1:63-80.
    • (1984) Psychol Med , vol.1 , pp. 63-80
    • Breitner, J.C.S.1    Folstein, M.F.2
  • 12
    • 0022641115 scopus 로고
    • Risk factors for clinically diagnosed Alzheimer's disease: A case control study of an Italian population
    • Amaducci LA, Fratiglioni L, Rocca WA et al. Risk factors for clinically diagnosed Alzheimer's disease: A case control study of an Italian population. Neurology 1986;36:922-931.
    • (1986) Neurology , vol.36 , pp. 922-931
    • Amaducci, L.A.1    Fratiglioni, L.2    Rocca, W.A.3
  • 13
    • 0023722471 scopus 로고
    • The inheritance of Alzheimer's disease: A new interpretation
    • Fitch N, Becker R, Heller A. The inheritance of Alzheimer's disease: A new interpretation. Ann Neurol 1988;23:14-19.
    • (1988) Ann Neurol , vol.23 , pp. 14-19
    • Fitch, N.1    Becker, R.2    Heller, A.3
  • 14
    • 0025768826 scopus 로고
    • Familial aggregation of Alzheimer's disease and related disorders: A collaborative re-analysis of case-control studies
    • van Duijn CM, Clayton D, Chandra V et al. Familial aggregation of Alzheimer's disease and related disorders: A collaborative re-analysis of case-control studies. Int J Epidemiol 1991;20(suppl 2):S13-20.
    • (1991) Int J Epidemiol , vol.20 , Issue.2 SUPPL.
    • Van Duijn, C.M.1    Clayton, D.2    Chandra, V.3
  • 15
    • 0023395768 scopus 로고
    • Case-control study of late onset "probable Alzheimer's disease"
    • Chandra V, Philipose V, Bell PA et al. Case-control study of late onset "probable Alzheimer's disease". Neurology 1987;37:1295-1300.
    • (1987) Neurology , vol.37 , pp. 1295-1300
    • Chandra, V.1    Philipose, V.2    Bell, P.A.3
  • 17
    • 0002089018 scopus 로고
    • Clinical genetics of familial Alzheimer disease
    • Terry RD, Katzman R, Bick KL, eds. New York: Raven Press
    • Bird TD. Clinical genetics of familial Alzheimer disease. In: Terry RD, Katzman R, Bick KL, eds. Alzheimer Disease. New York: Raven Press, 1994, pp 65-74.
    • (1994) Alzheimer Disease , pp. 65-74
    • Bird, T.D.1
  • 19
    • 0025897126 scopus 로고
    • Anatomic, metabolic, neuropsychological, and molecular genetic studies of three pairs of identical twins discordant for dementia of the Alzheimer's type
    • Kumar A, Schapiro MB, Grady CL et al. Anatomic, metabolic, neuropsychological, and molecular genetic studies of three pairs of identical twins discordant for dementia of the Alzheimer's type. Arch Neurol 1991;48:160-168.
    • (1991) Arch Neurol , vol.48 , pp. 160-168
    • Kumar, A.1    Schapiro, M.B.2    Grady, C.L.3
  • 20
    • 0024853631 scopus 로고
    • Monozygotic twins discordant for Alzheimer's disease
    • Creasey H, Jorm A, Longley W et al. Monozygotic twins discordant for Alzheimer's disease. Neurology 1989;39:1474-1476.
    • (1989) Neurology , vol.39 , pp. 1474-1476
    • Creasey, H.1    Jorm, A.2    Longley, W.3
  • 21
    • 0022453389 scopus 로고
    • Identical twins discordant for presenile dementia of the Alzheimer type
    • Renvoize EB, Mindham RHS, Stewart M et al. Identical twins discordant for presenile dementia of the Alzheimer type. Br J Psychiatry 1986;149:509-512.
    • (1986) Br J Psychiatry , vol.149 , pp. 509-512
    • Renvoize, E.B.1    Mindham, R.H.S.2    Stewart, M.3
  • 22
    • 0026466898 scopus 로고
    • Monozygotic twins concordant for late-onset probable Alzheimer disease with suspected Alzheimer disease in four sibs
    • Karlinsky H, Berg JM, Lennox A et al. Monozygotic twins concordant for late-onset probable Alzheimer disease with suspected Alzheimer disease in four sibs, Am J Med Genet 1992;44:591-597.
    • (1992) Am J Med Genet , vol.44 , pp. 591-597
    • Karlinsky, H.1    Berg, J.M.2    Lennox, A.3
  • 23
    • 0020692622 scopus 로고
    • A family with histologically confirmed Alzheimer's disease
    • Nee LE, Polinsky RJ, Eldridge R et al. A family with histologically confirmed Alzheimer's disease. Arch Neurol 1983;40:203-208.
    • (1983) Arch Neurol , vol.40 , pp. 203-208
    • Nee, L.E.1    Polinsky, R.J.2    Eldridge, R.3
  • 24
    • 0028060180 scopus 로고
    • Heredity in dementia of the Alzheimer type
    • Bergem ALM. Heredity in dementia of the Alzheimer type. Clin Genet 1994;46:144-149.
    • (1994) Clin Genet , vol.46 , pp. 144-149
    • Bergem, A.L.M.1
  • 25
    • 0029113637 scopus 로고
    • Alzheimer's disease in the National Academy of Sciences-National Research Council Registry of aging twin veterans. III. Detection of cases, longitudinal results, and observations on twin concordance
    • Breitner JCS, Welsh KA, Gau BA et al. Alzheimer's disease in the National Academy of Sciences-National Research Council Registry of aging twin veterans. III. Detection of cases, longitudinal results, and observations on twin concordance. Arch Neurol 1995;52:763-771.
    • (1995) Arch Neurol , vol.52 , pp. 763-771
    • Breitner, J.C.S.1    Welsh, K.A.2    Gau, B.A.3
  • 26
    • 0022655169 scopus 로고
    • Familial aggregation in Alzheimer dementia II: Clinical genetic implications of age-dependent onset
    • Breitner JCS, Murphy EA, Folstein MF. Familial aggregation in Alzheimer dementia II: Clinical genetic implications of age-dependent onset. J Psychiatr Res 1986;20:45-55.
    • (1986) J Psychiatr Res , vol.20 , pp. 45-55
    • Breitner, J.C.S.1    Murphy, E.A.2    Folstein, M.F.3
  • 27
    • 0029073383 scopus 로고
    • Genetic dissection of Alzheimer disease, a heterogeneous disorder
    • Schellenberg GD. Genetic dissection of Alzheimer disease, a heterogeneous disorder. Proc Natl Acad Sci USA 1995;92:8552-8559.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8552-8559
    • Schellenberg, G.D.1
  • 28
    • 0028883252 scopus 로고
    • Molecular genetics of Alzheimer disease: Identification of genes and gene mutations
    • Van Broeckhoven CL. Molecular genetics of Alzheimer disease: Identification of genes and gene mutations. Eur Neurol 1995;35:8-19.
    • (1995) Eur Neurol , vol.35 , pp. 8-19
    • Van Broeckhoven, C.L.1
  • 29
    • 0026088977 scopus 로고
    • Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
    • Goate A, Chartier-Harlin MC, Mullan M et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 1991;349:704-706.
    • (1991) Nature , vol.349 , pp. 704-706
    • Goate, A.1    Chartier-Harlin, M.C.2    Mullan, M.3
  • 30
    • 0022614193 scopus 로고
    • Down's syndrome and Alzheimer's disease: A review
    • Oliver C, Holland AJ. Down's syndrome and Alzheimer's disease: A review. Psychol Med 1986;16:307-322.
    • (1986) Psychol Med , vol.16 , pp. 307-322
    • Oliver, C.1    Holland, A.J.2
  • 31
    • 0025296269 scopus 로고
    • Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type
    • Levy E, Carman MD, Fernandez-Madrid IJ et al. Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type. Science 1990;248:1124-1126.
    • (1990) Science , vol.248 , pp. 1124-1126
    • Levy, E.1    Carman, M.D.2    Fernandez-Madrid, I.J.3
  • 32
    • 0028322017 scopus 로고
    • An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants
    • Suzuki N, Cheung TT, Cai XD et al. An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants. Science 1994;264:1336-1340.
    • (1994) Science , vol.264 , pp. 1336-1340
    • Suzuki, N.1    Cheung, T.T.2    Cai, X.D.3
  • 33
    • 0026595567 scopus 로고
    • Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs
    • Burdick D, Soreghan B, Kwon M et al. Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs. J Biol Chem 1992;267:546-554.
    • (1992) J Biol Chem , vol.267 , pp. 546-554
    • Burdick, D.1    Soreghan, B.2    Kwon, M.3
  • 34
    • 0026471656 scopus 로고
    • Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14
    • Schellenberg GD, Bird TD, Wijsman EM et al. Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14. Science 1992;258:668-671.
    • (1992) Science , vol.258 , pp. 668-671
    • Schellenberg, G.D.1    Bird, T.D.2    Wijsman, E.M.3
  • 35
    • 0029004341 scopus 로고
    • Cloning of a gene bearing missense mutation in early-onset familial Alzheimer's disease
    • Sherrington R, Rogaev EI, Liang Y et al. Cloning of a gene bearing missense mutation in early-onset familial Alzheimer's disease. Nature 1995;375:754-760.
    • (1995) Nature , vol.375 , pp. 754-760
    • Sherrington, R.1    Rogaev, E.I.2    Liang, Y.3
  • 36
    • 0029027649 scopus 로고
    • Missense on the membrane
    • Selkoe DJ. Missense on the membrane. Nature 1995;375:734-735.
    • (1995) Nature , vol.375 , pp. 734-735
    • Selkoe, D.J.1
  • 37
    • 0029052710 scopus 로고
    • Familial Alzheimer's chromosome 14 mutations
    • Wasco W, Pettingell WP, Jondro PD et al. Familial Alzheimer's chromosome 14 mutations. Nature Med 1995;1:848.
    • (1995) Nature Med , vol.1 , pp. 848
    • Wasco, W.1    Pettingell, W.P.2    Jondro, P.D.3
  • 38
    • 0029411573 scopus 로고
    • Presenilins and Alzheimer disease
    • Van Broeckhoven C. Presenilins and Alzheimer disease. Nature Genet 1995;11:230-232.
    • (1995) Nature Genet , vol.11 , pp. 230-232
    • Van Broeckhoven, C.1
  • 39
    • 0029087026 scopus 로고
    • Candidate gene for the chromosome 1 familial Alzheimer's disease locus
    • Levy-Lahad E, Wasco W, Poorkaj P et al. Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science 1995;269:973-977.
    • (1995) Science , vol.269 , pp. 973-977
    • Levy-Lahad, E.1    Wasco, W.2    Poorkaj, P.3
  • 40
    • 0029150716 scopus 로고
    • A familial Alzheimer's disease locus on chromosome 1
    • Levy-Lahad E, Wijsman EM, Nemens E et al. A familial Alzheimer's disease locus on chromosome 1. Science 1995;269:970-973.
    • (1995) Science , vol.269 , pp. 970-973
    • Levy-Lahad, E.1    Wijsman, E.M.2    Nemens, E.3
  • 41
    • 0029101491 scopus 로고
    • Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene
    • Rogaev EI, Sherrington R, Rogaeva EA et al. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature 1995;376:775-776.
    • (1995) Nature , vol.376 , pp. 775-776
    • Rogaev, E.I.1    Sherrington, R.2    Rogaeva, E.A.3
  • 42
    • 0028978471 scopus 로고
    • Beta APP mRNA transcription is increased in cultured fibroblasts from the familial Alzheimer's disease-1 family
    • Querfurth HW, Wijsman EM, St George-Hyslop PH, Selkoe DJ. Beta APP mRNA transcription is increased in cultured fibroblasts from the familial Alzheimer's disease-1 family. Acta Neurol Belg 1995;28:319-337.
    • (1995) Acta Neurol Belg , vol.28 , pp. 319-337
    • Querfurth, H.W.1    Wijsman, E.M.2    St George-Hyslop, P.H.3    Selkoe, D.J.4
  • 43
    • 0025735884 scopus 로고
    • Linkage studies in familial Alzheimer disease: Evidence for chromosome 19 linkage
    • Pericak-Vance MA, Bebout JL, Gaskell PC et al. Linkage studies in familial Alzheimer disease: Evidence for chromosome 19 linkage. Am J Hum Genet 1991;48:1034-1050.
    • (1991) Am J Hum Genet , vol.48 , pp. 1034-1050
    • Pericak-Vance, M.A.1    Bebout, J.L.2    Gaskell, P.C.3
  • 44
    • 0027407565 scopus 로고
    • Apolipoprotein E: Highavidity binding to B-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
    • Strittmatter WJ, Saunders AM, Schmechel D et al. Apolipoprotein E: highavidity binding to B-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci USA 1993;90:1977-1981.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 1977-1981
    • Strittmatter, W.J.1    Saunders, A.M.2    Schmechel, D.3
  • 45
    • 0027194791 scopus 로고
    • Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
    • Corder EH, Saunders AM, Strittmatter WJ et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families, Science 1993;261:921-923.
    • (1993) Science , vol.261 , pp. 921-923
    • Corder, E.H.1    Saunders, A.M.2    Strittmatter, W.J.3
  • 46
    • 0027365822 scopus 로고
    • Increased amyloid B-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease
    • Schmechel DE, Saunders AM, Strittmatter WJ et al. Increased amyloid B-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease. Proc Natl Acad Sci USA 1993;90:9649-9653.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 9649-9653
    • Schmechel, D.E.1    Saunders, A.M.2    Strittmatter, W.J.3
  • 47
    • 0027374047 scopus 로고
    • Apolipoprotein E in sporadic Alzheimer's disease: Allelic variation and receptor interactions
    • Rebeck GW, Reiter JS, Strickland DK, Hyman BT. Apolipoprotein E in sporadic Alzheimer's disease: Allelic variation and receptor interactions. Neuron 1993;11:575-580.
    • (1993) Neuron , vol.11 , pp. 575-580
    • Rebeck, G.W.1    Reiter, J.S.2    Strickland, D.K.3    Hyman, B.T.4
  • 48
    • 0027327267 scopus 로고
    • Association of apolipoprotein E allele E4 with late-onset familial and sporadic Alzheimer's disease
    • Saunders AM, Strittmatter WJ, Schmechel D et al. Association of apolipoprotein E allele E4 with late-onset familial and sporadic Alzheimer's disease. Neurology 1993;43:1467-1472.
    • (1993) Neurology , vol.43 , pp. 1467-1472
    • Saunders, A.M.1    Strittmatter, W.J.2    Schmechel, D.3
  • 49
    • 0028167193 scopus 로고
    • Confirmation of the E4 allele of the apolipoprotein E gene as a risk factor for late-onset Alzheimer's disease
    • Brousseau T, Legrain S, Berr C et al. Confirmation of the E4 allele of the apolipoprotein E gene as a risk factor for late-onset Alzheimer's disease. Neurology 1994;44:342-344.
    • (1994) Neurology , vol.44 , pp. 342-344
    • Brousseau, T.1    Legrain, S.2    Berr, C.3
  • 50
    • 0027339923 scopus 로고
    • The apolipoprotein E4 allele in patients with Alzheimer's disease
    • Mayeux R, Stern Y, Ottman R et al. The apolipoprotein E4 allele in patients with Alzheimer's disease. Ann Neurol 1993;34:752-754.
    • (1993) Ann Neurol , vol.34 , pp. 752-754
    • Mayeux, R.1    Stern, Y.2    Ottman, R.3
  • 51
    • 0028167740 scopus 로고
    • Association of apolipoprotein E phenotypes with late onset Alzheimer's disease: Population based study
    • Kuusisto J, Koivisto K, Kervinen K et al. Association of apolipoprotein E phenotypes with late onset Alzheimer's disease: Population based study. Br Med J 1994;309:636-638.
    • (1994) Br Med J , vol.309 , pp. 636-638
    • Kuusisto, J.1    Koivisto, K.2    Kervinen, K.3
  • 52
    • 0028858763 scopus 로고
    • Apolipoprotein E polymorphism and Alzheimer's disease in Eastern Finland
    • Lehtovirta M, Helisalmi S, Mannermaa A et al. Apolipoprotein E polymorphism and Alzheimer's disease in Eastern Finland. Neurosci Lett 1995;185:13-15.
    • (1995) Neurosci Lett , vol.185 , pp. 13-15
    • Lehtovirta, M.1    Helisalmi, S.2    Mannermaa, A.3
  • 53
    • 0028026997 scopus 로고
    • Apolipoprotein e4 allele in a population-based study of early-onset Alzheimer's disease
    • van Duijn CM, de Knijff P, Cruts M et al. Apolipoprotein e4 allele in a population-based study of early-onset Alzheimer's disease. Nature Genet 1994;7:74-78.
    • (1994) Nature Genet , vol.7 , pp. 74-78
    • Van Duijn, C.M.1    De Knijff, P.2    Cruts, M.3
  • 55
    • 0028301820 scopus 로고
    • Apolipoprotein E: Risk factor for Alzheimer disease
    • Tsai MS, Tangalos EG, Petersen RC et al. Apolipoprotein E: Risk factor for Alzheimer disease. Am J Hum Genet 1994;54:643-649.
    • (1994) Am J Hum Genet , vol.54 , pp. 643-649
    • Tsai, M.S.1    Tangalos, E.G.2    Petersen, R.C.3
  • 56
    • 0027921547 scopus 로고
    • Apolipoprotein E-e4 allele and Alzheimer's disease
    • Lucorte G, David F, Visvikis S et al. Apolipoprotein E-e4 allele and Alzheimer's disease. Lancet 1993;342:1309.
    • (1993) Lancet , vol.342 , pp. 1309
    • Lucorte, G.1    David, F.2    Visvikis, S.3
  • 57
    • 0028289326 scopus 로고
    • Confirmation of association between the e4 allele of apolipoprotein E and Alzheimer's disease
    • Liddell M, Williams J, Bayer A et al. Confirmation of association between the e4 allele of apolipoprotein E and Alzheimer's disease. J Med Genet 1994;31:197-200.
    • (1994) J Med Genet , vol.31 , pp. 197-200
    • Liddell, M.1    Williams, J.2    Bayer, A.3
  • 58
    • 0028141602 scopus 로고
    • Association of apolipoprotein E allele ∈4 with late-onset sporadic Alzheimer's disease
    • Lucotte G, Visvikis B, Leininger-Muler B et al. Association of apolipoprotein E allele ∈4 with late-onset sporadic Alzheimer's disease. Am J Med Genet 1994;54:286-288.
    • (1994) Am J Med Genet , vol.54 , pp. 286-288
    • Lucotte, G.1    Visvikis, B.2    Leininger-Muler, B.3
  • 59
    • 0028278679 scopus 로고
    • Apolipoprotein E4: Phenotype in patients with Alzheimer's disease
    • Mahieux F, Couderc R, Moulignier A et al. Apolipoprotein E4: Phenotype in patients with Alzheimer's disease. Ann Neurol 1994;35:506.
    • (1994) Ann Neurol , vol.35 , pp. 506
    • Mahieux, F.1    Couderc, R.2    Moulignier, A.3
  • 60
    • 0027946816 scopus 로고
    • Predictive value of apolipoprotein E genotyping in Alzheimer's disease: Results of an autopsy series and an analysis of several combined studies
    • Nalbantoglu J, Gilfix BM, Bertrand P et al. Predictive value of apolipoprotein E genotyping in Alzheimer's disease: Results of an autopsy series and an analysis of several combined studies. Ann Neurol 1994;36:889-895.
    • (1994) Ann Neurol , vol.36 , pp. 889-895
    • Nalbantoglu, J.1    Gilfix, B.M.2    Bertrand, P.3
  • 61
    • 0028816355 scopus 로고
    • Apolipoprotein E and Alzheimer's disease: Ethnic variation in genotypic risks
    • Maestre G, Ottman R, Stern Y et al. Apolipoprotein E and Alzheimer's disease: Ethnic variation in genotypic risks. Ann Neurol 1995;37:254-259.
    • (1995) Ann Neurol , vol.37 , pp. 254-259
    • Maestre, G.1    Ottman, R.2    Stern, Y.3
  • 62
    • 0028305380 scopus 로고
    • Apolipoprotein E type 2 allele decreases the risk of late onset Alzheimer disease
    • Corder EH, Saunders AM, Risch NJ et al. Apolipoprotein E type 2 allele decreases the risk of late onset Alzheimer disease. Nature Genet 1994;7:180-184.
    • (1994) Nature Genet , vol.7 , pp. 180-184
    • Corder, E.H.1    Saunders, A.M.2    Risch, N.J.3
  • 63
    • 0029901395 scopus 로고    scopus 로고
    • Impact of sample selection of APOE ∈4 allele frequency: A comparison of two Alzheimer's disease samples
    • Tsuang D, Kukull W, Sheppard L et al. Impact of sample selection of APOE ∈4 allele frequency: A comparison of two Alzheimer's disease samples. J Am Geriatr Soc 1996;44:704-707.
    • (1996) J Am Geriatr Soc , vol.44 , pp. 704-707
    • Tsuang, D.1    Kukull, W.2    Sheppard, L.3
  • 64
    • 0028282762 scopus 로고
    • Frequency of the apolipoprotein E ∈2 allele is diminished in sporadic Alzheimer disease
    • West HL, Rebeck W, Hyman BT. Frequency of the apolipoprotein E ∈2 allele is diminished in sporadic Alzheimer disease. Neurosci Lett 1994;175:46-48.
    • (1994) Neurosci Lett , vol.175 , pp. 46-48
    • West, H.L.1    Rebeck, W.2    Hyman, B.T.3
  • 65
    • 0028278060 scopus 로고
    • Protection against Alzheimer's disease with apoE e2
    • Talbot C, Lendon C, Craddock N et al. Protection against Alzheimer's disease with apoE e2. Lancet 1994;343:1432-1433.
    • (1994) Lancet , vol.343 , pp. 1432-1433
    • Talbot, C.1    Lendon, C.2    Craddock, N.3
  • 66
    • 0028178047 scopus 로고
    • Apolipoprotein E, e4 as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: Analysis of the 19q13.2 chromosomal region
    • Chartier-Harlin MC, Parfitt M, Legrain S et al. Apolipoprotein E, e4 as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: Analysis of the 19q13.2 chromosomal region. Hum Mol Genet 1994;3:569-574.
    • (1994) Hum Mol Genet , vol.3 , pp. 569-574
    • Chartier-Harlin, M.C.1    Parfitt, M.2    Legrain, S.3
  • 67
    • 0028843391 scopus 로고
    • Apolipoprotein E4 allele and Alzheimer disease: Examination of allelic association and effect on age at onset in both early- And late-onset cases
    • Locke PA, Conneally PM, Tanzi RE et al. Apolipoprotein E4 allele and Alzheimer disease: Examination of allelic association and effect on age at onset in both early- and late-onset cases. Genet Epidemiol 1995;12:83-92.
    • (1995) Genet Epidemiol , vol.12 , pp. 83-92
    • Locke, P.A.1    Conneally, P.M.2    Tanzi, R.E.3
  • 68
    • 0028772164 scopus 로고
    • Protective effect of apo epsilon 2 in Alzheimer's disease. Oxford Project to Investigate Memory and Ageing
    • Smith AD, Johnston C, Sim E et al. Protective effect of apo epsilon 2 in Alzheimer's disease. Oxford Project to Investigate Memory and Ageing. Lancet 1994;34:473-474.
    • (1994) Lancet , vol.34 , pp. 473-474
    • Smith, A.D.1    Johnston, C.2    Sim, E.3
  • 69
    • 0028988736 scopus 로고
    • The apolipoprotein E E2 allele is associated with an increased risk of early-onset Alzheimer's disease and a reduced survival
    • van Duijn CM, de Knijff P, Wehnert A et al. The apolipoprotein E E2 allele is associated with an increased risk of early-onset Alzheimer's disease and a reduced survival. Ann Neurol 1995;37:605-610.
    • (1995) Ann Neurol , vol.37 , pp. 605-610
    • Van Duijn, C.M.1    De Knijff, P.2    Wehnert, A.3
  • 70
    • 0028091522 scopus 로고
    • Influence of apolipoprotein E genotype on senile dementia of the Alzheimer and Lewy body types
    • Harrington CR, Louwagie J, Rossau R et al. Influence of apolipoprotein E genotype on senile dementia of the Alzheimer and Lewy body types. Am J Pathol 1994;145:1472-1484.
    • (1994) Am J Pathol , vol.145 , pp. 1472-1484
    • Harrington, C.R.1    Louwagie, J.2    Rossau, R.3
  • 71
    • 0028113971 scopus 로고
    • The apolipoprotein E allele E4 is overrepresented in patients with the Lewy body variant of Alzheimer's disease
    • Galasko D, Saitoh T, Xia Y et al. The apolipoprotein E allele E4 is overrepresented in patients with the Lewy body variant of Alzheimer's disease. Neurology 1994;44:1950-1951.
    • (1994) Neurology , vol.44 , pp. 1950-1951
    • Galasko, D.1    Saitoh, T.2    Xia, Y.3
  • 72
    • 0028206406 scopus 로고
    • Apolipoprotein E genes in Lewy body and Parkinson's disease
    • Benjamin R, Leake A, Edwardson JA et al. Apolipoprotein E genes in Lewy body and Parkinson's disease. Lancet 1994;343:1565.
    • (1994) Lancet , vol.343 , pp. 1565
    • Benjamin, R.1    Leake, A.2    Edwardson, J.A.3
  • 73
    • 12044254746 scopus 로고
    • Binding of human apolipoprotein E to synthetic amyloid B peptide: Isoform-specific effects and implications for late-onset Alzheimer disease
    • Strittmatter WJ, Weisgraber KH, Huang DY et al. Binding of human apolipoprotein E to synthetic amyloid B peptide: isoform-specific effects and implications for late-onset Alzheimer disease. Proc Natl Acad Sci USA 1993;90:8098-8102.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 8098-8102
    • Strittmatter, W.J.1    Weisgraber, K.H.2    Huang, D.Y.3
  • 74
    • 0028269666 scopus 로고
    • Hypothesis: Microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype
    • Strittmatter WJ, Weisgraber KH, Goedert M, et al. Hypothesis: Microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype. Exp Neurol 1994;125:163-171.
    • (1994) Exp Neurol , vol.125 , pp. 163-171
    • Strittmatter, W.J.1    Weisgraber, K.H.2    Goedert, M.3
  • 75
    • 0028172930 scopus 로고
    • Apolipoprotein E in animal models of CNS injury and in Alzheimer's disease
    • Poirier J. Apolipoprotein E in animal models of CNS injury and in Alzheimer's disease. Trends Neurosci 1994;17:525-530.
    • (1994) Trends Neurosci , vol.17 , pp. 525-530
    • Poirier, J.1
  • 76
    • 0011360063 scopus 로고
    • Abnormal synaptic regeneration in hAPP transgenic and APOE-knockout mice
    • Masliah E, Mallory M, Alford M, Mucke L. Abnormal synaptic regeneration in hAPP transgenic and APOE-knockout mice. Neurobiol Aging 1994;15:S11.
    • (1994) Neurobiol Aging , vol.15
    • Masliah, E.1    Mallory, M.2    Alford, M.3    Mucke, L.4
  • 77
    • 0026698267 scopus 로고
    • Apolipoprotein E polymorphism in a Danish population compared to findings in 45 other study populations around the world
    • Gerdes LU, Klausen IC, Sihm I, Gaergeman O. Apolipoprotein E polymorphism in a Danish population compared to findings in 45 other study populations around the world. Genet Epidemiol 1992;9:155-167.
    • (1992) Genet Epidemiol , vol.9 , pp. 155-167
    • Gerdes, L.U.1    Klausen, I.C.2    Sihm, I.3    Gaergeman, O.4
  • 78
    • 0026349433 scopus 로고
    • The apolipoprotein E polymorphism: A comparison of allele frequencies and effects in nine populations
    • Hallman DM, Boerwinkle E, Saha N et al. The apolipoprotein E polymorphism: A comparison of allele frequencies and effects in nine populations. Am J Hum Genet 1991;49:338-349.
    • (1991) Am J Hum Genet , vol.49 , pp. 338-349
    • Hallman, D.M.1    Boerwinkle, E.2    Saha, N.3
  • 79
    • 0028961402 scopus 로고
    • Apolipoprotein E genotypes and Alzheimer's disease in a community study of elderly African Americans
    • Hendrie HC, Hall KS, Hui S et al. Apolipoprotein E genotypes and Alzheimer's disease in a community study of elderly African Americans. Ann Neurol 1995;37:118-120.
    • (1995) Ann Neurol , vol.37 , pp. 118-120
    • Hendrie, H.C.1    Hall, K.S.2    Hui, S.3
  • 80
    • 0029037609 scopus 로고
    • Lack of association of apolipoprotein E allele epsilon-4 with late-onset Alzheimer's disease among Finnish centenarians
    • Sobel E, Louhija J, Sulkava R. Lack of association of apolipoprotein E allele epsilon-4 with late-onset Alzheimer's disease among Finnish centenarians. Neurology 1995;45:903-907.
    • (1995) Neurology , vol.45 , pp. 903-907
    • Sobel, E.1    Louhija, J.2    Sulkava, R.3
  • 81
    • 0027984085 scopus 로고
    • Apolipoprotein E is a relevant susceptibility gene that affects the rate of expression of Alzheimer's disease
    • Roses AD. Apolipoprotein E is a relevant susceptibility gene that affects the rate of expression of Alzheimer's disease. Neurobiol Aging 1994;15 (suppl 2):S165-167.
    • (1994) Neurobiol Aging , vol.15 , Issue.2 SUPPL.
    • Roses, A.D.1
  • 82
    • 0023786551 scopus 로고
    • Age-dependent expression of familial risk in Alzheimer's disease
    • Breitner JCS, Murphy EA, Silverman JM et al. Age-dependent expression of familial risk in Alzheimer's disease. Am J Epidemiol 1988;128:536-548.
    • (1988) Am J Epidemiol , vol.128 , pp. 536-548
    • Breitner, J.C.S.1    Murphy, E.A.2    Silverman, J.M.3
  • 83
    • 0025995623 scopus 로고
    • Clinical genetics and genetic counseling in Alzheimer's disease
    • Breitner JCS. Clinical genetics and genetic counseling in Alzheimer's disease. Ann Intern Med 1991;115:601-606.
    • (1991) Ann Intern Med , vol.115 , pp. 601-606
    • Breitner, J.C.S.1
  • 84
    • 0029001744 scopus 로고
    • Epistatic effect of APP717 mutation and apolipoprotein E genotype in familial Alzheimer's disease
    • Sorbi S, Nacmias B, Forleo P et al. Epistatic effect of APP717 mutation and apolipoprotein E genotype in familial Alzheimer's disease. Ann Neurol 1995;38:124-127.
    • (1995) Ann Neurol , vol.38 , pp. 124-127
    • Sorbi, S.1    Nacmias, B.2    Forleo, P.3
  • 86
    • 0028350675 scopus 로고
    • APOE genotype does not modulate age of onset in families with chromosome 14 encoded Alzheimer's disease
    • Van Broeckhoven C. APOE genotype does not modulate age of onset in families with chromosome 14 encoded Alzheimer's disease. Neurosci Lett 1994;169:179-180.
    • (1994) Neurosci Lett , vol.169 , pp. 179-180
    • Van Broeckhoven, C.1
  • 87
    • 0029166112 scopus 로고
    • Apolipoprotein E genotypes and age of onset in early-onset familial Alzheimer's disease
    • Levy-Lahad E, Lahad A, Wijsman EM, Bird TD, Schellenberg GD. Apolipoprotein E genotypes and age of onset in early-onset familial Alzheimer's disease. Ann Neurol 1995;38:678-680.
    • (1995) Ann Neurol , vol.38 , pp. 678-680
    • Levy-Lahad, E.1    Lahad, A.2    Wijsman, E.M.3    Bird, T.D.4    Schellenberg, G.D.5
  • 89
    • 0028114327 scopus 로고
    • Genetic studies of Alzheimer's disease: Lessons learned and future imperatives
    • Tanzi RE, Bush AI, Wasco W. Genetic studies of Alzheimer's disease: Lessons learned and future imperatives. Neurobiol Aging 1994;15(suppl 2):S145-148.
    • (1994) Neurobiol Aging , vol.15 , Issue.2 SUPPL.
    • Tanzi, R.E.1    Bush, A.I.2    Wasco, W.3
  • 90
    • 0028997817 scopus 로고
    • Apolipoprotein E genotyping in the differential diagnosis, not prediction, of Alzheimer's disease
    • Roses AD. Apolipoprotein E genotyping in the differential diagnosis, not prediction, of Alzheimer's disease. Ann Neurol 1995;38:6-14.
    • (1995) Ann Neurol , vol.38 , pp. 6-14
    • Roses, A.D.1
  • 91
    • 0025913996 scopus 로고
    • Head trauma as a risk factor for Alzheimer's disease: A collaborative re-analysis of case-control studies
    • Mortimer JA, van Duijn CM, Chandra V et al. Head trauma as a risk factor for Alzheimer's disease: A collaborative re-analysis of case-control studies. Int J Epidemiol 1991;20(suppl 2):S28-35.
    • (1991) Int J Epidemiol , vol.20 , Issue.2 SUPPL.
    • Mortimer, J.A.1    Van Duijn, C.M.2    Chandra, V.3
  • 92
    • 0027235553 scopus 로고
    • Genetic susceptibility and head injury as risk factors for Alzheimer's disease among community-dwelling elderly persons and their first-degree relatives
    • Mayeux R, Ottman R, Tang M-X et al. Genetic susceptibility and head injury as risk factors for Alzheimer's disease among community-dwelling elderly persons and their first-degree relatives. Ann Neurol 1993;33:494-501.
    • (1993) Ann Neurol , vol.33 , pp. 494-501
    • Mayeux, R.1    Ottman, R.2    Tang, M.-X.3
  • 93
    • 0026723683 scopus 로고
    • Head trauma and the risk of Alzheimer's disease
    • van Duijn CM, Tanja TA, Haaxma R et al. Head trauma and the risk of Alzheimer's disease. Am J Epidemiol 1992;135:775-782.
    • (1992) Am J Epidemiol , vol.135 , pp. 775-782
    • Van Duijn, C.M.1    Tanja, T.A.2    Haaxma, R.3
  • 94
    • 0025012855 scopus 로고
    • The association between head trauma and Alzheimer's disease
    • Graves AB, White E, Koepsell TD et al. The association between head trauma and Alzheimer's disease. Am J Epidemiol 1990;131:491-501.
    • (1990) Am J Epidemiol , vol.131 , pp. 491-501
    • Graves, A.B.1    White, E.2    Koepsell, T.D.3
  • 95
    • 0029018224 scopus 로고
    • Synergistic effects of traumatic head injury and apolipoprotein-epsilon 4 in patients with Alzheimer's disease
    • Mayeux R, Ottman R, Maestre G et al. Synergistic effects of traumatic head injury and apolipoprotein-epsilon 4 in patients with Alzheimer's disease. Neurology 1995;45:555-557.
    • (1995) Neurology , vol.45 , pp. 555-557
    • Mayeux, R.1    Ottman, R.2    Maestre, G.3
  • 96
    • 0026523166 scopus 로고
    • Relation of smoking and alcohol consumption to incident Alzheimer's disease
    • Hebert LE, Scherr PA, Beckett LA et al. Relation of smoking and alcohol consumption to incident Alzheimer's disease. Am J Epidemiol 1992;135:347-355.
    • (1992) Am J Epidemiol , vol.135 , pp. 347-355
    • Hebert, L.E.1    Scherr, P.A.2    Beckett, L.A.3
  • 97
    • 10144230778 scopus 로고
    • Education, occupation, and Alzheimer's disease
    • Stern Y, Mayeux R. Education, occupation, and Alzheimer's disease. JAMA 1994;272:1406.
    • (1994) JAMA , vol.272 , pp. 1406
    • Stern, Y.1    Mayeux, R.2
  • 98
    • 0028080315 scopus 로고
    • The Canadian Study of Health and Aging: Risk factors for Alzheimer's disease in Canada
    • McDowell I, Hill G, Lindsay J et al. The Canadian Study of Health and Aging: Risk factors for Alzheimer's disease in Canada. Neurology 1994;44:2073-2080.
    • (1994) Neurology , vol.44 , pp. 2073-2080
    • McDowell, I.1    Hill, G.2    Lindsay, J.3
  • 99
    • 0030066467 scopus 로고    scopus 로고
    • Linguistic ability in early life and cognitive function and Alzheimer's disease in late life
    • Snowdon DA, Kemper SJ, Mortimer JA et al. Linguistic ability in early life and cognitive function and Alzheimer's disease in late life. JAMA 1996;275:528-532.
    • (1996) JAMA , vol.275 , pp. 528-532
    • Snowdon, D.A.1    Kemper, S.J.2    Mortimer, J.A.3
  • 100
    • 0029071213 scopus 로고
    • Intelligence and education as predictors of cognitive state in late life: A 50 year follow-up
    • Plassman BL, Welsh KA, Helms M et al. Intelligence and education as predictors of cognitive state in late life: A 50 year follow-up. Neurology 1995;45:1446-1450.
    • (1995) Neurology , vol.45 , pp. 1446-1450
    • Plassman, B.L.1    Welsh, K.A.2    Helms, M.3
  • 102
    • 0028365441 scopus 로고
    • Smoking and Alzheimer's disease: A review of the epidemiological evidence
    • Lee PN. Smoking and Alzheimer's disease: A review of the epidemiological evidence. Neuroepidemiology 1994;13:131-144.
    • (1994) Neuroepidemiology , vol.13 , pp. 131-144
    • Lee, P.N.1
  • 103
    • 0028894408 scopus 로고
    • Smoking, Alzheimer's disease, and confounding with genes
    • Plassman BL, Helms MJ, Welsh KA et al. Smoking, Alzheimer's disease, and confounding with genes. Lancet 1995;345:387.
    • (1995) Lancet , vol.345 , pp. 387
    • Plassman, B.L.1    Helms, M.J.2    Welsh, K.A.3
  • 104
    • 84928550859 scopus 로고    scopus 로고
    • Inflammatory processes and anti-inflammatory drugs in Alzheimer's disease: A current appraisal
    • in press
    • Breitner JCS. Inflammatory processes and anti-inflammatory drugs in Alzheimer's disease: A current appraisal. Neurobiol Aging (in press).
    • Neurobiol Aging
    • Breitner, J.C.S.1
  • 105
    • 0028289083 scopus 로고
    • Inverse association of antiinflammatory treatments and Alzheimer's disease: Initial results of a cotwin control study
    • Breitner JCS, Gau BA, Welsh KA et al. Inverse association of antiinflammatory treatments and Alzheimer's disease: Initial results of a cotwin control study. Neurology 1994;44:227-232.
    • (1994) Neurology , vol.44 , pp. 227-232
    • Breitner, J.C.S.1    Gau, B.A.2    Welsh, K.A.3
  • 106
    • 0029160270 scopus 로고
    • Delayed onset of Alzheimer's disease with non-steroidal anti-inflammatory and histamine H2-blocking drugs
    • Breitner JCS, Welsh KA, Helms MJ et al. Delayed onset of Alzheimer's disease with non-steroidal anti-inflammatory and histamine H2-blocking drugs. Neurobiol Aging 1995;16:523-530.
    • (1995) Neurobiol Aging , vol.16 , pp. 523-530
    • Breitner, J.C.S.1    Welsh, K.A.2    Helms, M.J.3
  • 107
  • 108
    • 0027973579 scopus 로고
    • Lower cognitive performance in normal older adult male twins carrying the apolipoprotein E E4 allele
    • Reed T, Carmelli D, Swan GE et al. Lower cognitive performance in normal older adult male twins carrying the apolipoprotein E E4 allele. Arch Neurol 1994;51:1189-1192.
    • (1994) Arch Neurol , vol.51 , pp. 1189-1192
    • Reed, T.1    Carmelli, D.2    Swan, G.E.3
  • 109
    • 0029440749 scopus 로고
    • Episodic memory changes are associated with the APOE-epsilon-4 allele in nondemented older adults
    • Bondi MW, Salmon DP, Monsch AU et al. Episodic memory changes are associated with the APOE-epsilon-4 allele in nondemented older adults. Neurology 1995;45:2203-2206.
    • (1995) Neurology , vol.45 , pp. 2203-2206
    • Bondi, M.W.1    Salmon, D.P.2    Monsch, A.U.3
  • 110
    • 0028950856 scopus 로고
    • Apolipoprotein E type 4 allele and cerebral glucose metabolism in relatives at risk for familial Alzheimer's disease
    • Small GW, Mazziotta JC, Collins MT et al. Apolipoprotein E type 4 allele and cerebral glucose metabolism in relatives at risk for familial Alzheimer's disease. JAMA 1995;273:942-947.
    • (1995) JAMA , vol.273 , pp. 942-947
    • Small, G.W.1    Mazziotta, J.C.2    Collins, M.T.3
  • 111
    • 0028898784 scopus 로고
    • Apolipoprotein E status as a predictor of the development of Alzheimer's disease in memory-impaired individuals
    • Petersen RC, Smith GE, Ivnik RJ et al. Apolipoprotein E status as a predictor of the development of Alzheimer's disease in memory-impaired individuals. JAMA 1995;273:1274-1278.
    • (1995) JAMA , vol.273 , pp. 1274-1278
    • Petersen, R.C.1    Smith, G.E.2    Ivnik, R.J.3
  • 112
    • 0007691164 scopus 로고
    • Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer disease
    • Poirier J, Delisle MC, Quirion R et al. Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer disease. Proc Natl Acad Sci USA 1995;92:12260-12264.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 12260-12264
    • Poirier, J.1    Delisle, M.C.2    Quirion, R.3
  • 115
    • 0027404280 scopus 로고
    • A population-based study of dementia in 85-year-olds
    • Skoog I, Nilsson L, Palmertz B et al. A population-based study of dementia in 85-year-olds. N Engl J Med 1993;328:153-158.
    • (1993) N Engl J Med , vol.328 , pp. 153-158
    • Skoog, I.1    Nilsson, L.2    Palmertz, B.3
  • 116
    • 0023885244 scopus 로고
    • Vascular dementia is overdiagnosed
    • Brust JCM. Vascular dementia is overdiagnosed. Arch Neurol 1988;45:799-801.
    • (1988) Arch Neurol , vol.45 , pp. 799-801
    • Brust, J.C.M.1
  • 117
    • 0027411093 scopus 로고
    • Making the diagnosis of Alzheimer's disease: A primer for practicing pathologists
    • Mirra SS, Hart MN, Terry RD. Making the diagnosis of Alzheimer's disease: A primer for practicing pathologists. Arch Pathol Lab Med 1993;177:132-144.
    • (1993) Arch Pathol Lab Med , vol.177 , pp. 132-144
    • Mirra, S.S.1    Hart, M.N.2    Terry, R.D.3
  • 119
    • 0017750160 scopus 로고
    • Hereditary multi-infarct dementia
    • Sourander P, Walinder J. Hereditary multi-infarct dementia. Acta Neuropathol 1977;39:247-254.
    • (1977) Acta Neuropathol , vol.39 , pp. 247-254
    • Sourander, P.1    Walinder, J.2
  • 120
    • 0028108538 scopus 로고
    • Progress in the genetics of cerebrovascular disease: Inherited subcortical arteriopathies
    • Bowler JV, Hachinski V. Progress in the genetics of cerebrovascular disease: Inherited subcortical arteriopathies. Stroke 1994;25:1696-1699.
    • (1994) Stroke , vol.25 , pp. 1696-1699
    • Bowler, J.V.1    Hachinski, V.2
  • 121
    • 0027479304 scopus 로고
    • Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy maps to chromosome 19q12
    • Tournier-Lasserve E, Joutel A, Melki J et al. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy maps to chromosome 19q12. Nature Genet 1993;3:256-259.
    • (1993) Nature Genet , vol.3 , pp. 256-259
    • Tournier-Lasserve, E.1    Joutel, A.2    Melki, J.3
  • 122
    • 0010614244 scopus 로고
    • CADASIL: Clinical phenotypes and genetic data in 15 unrelated families
    • Tournier-Lasserve E, Joutel A, Chabriat H et al. CADASIL: Clinical phenotypes and genetic data in 15 unrelated families. Neurology 1995;45(suppl 4):A273.
    • (1995) Neurology , vol.45 , Issue.4 SUPPL.
    • Tournier-Lasserve, E.1    Joutel, A.2    Chabriat, H.3
  • 123
    • 0025367646 scopus 로고
    • Hereditary cerebral hemorrhage with amyloidosis-Dutch type. Clinical and computed tomographic analysis of 24 cases
    • Haan J, Algra PR, Roos RA. Hereditary cerebral hemorrhage with amyloidosis-Dutch type. Clinical and computed tomographic analysis of 24 cases. Arch Neurol 1990;47:649-653.
    • (1990) Arch Neurol , vol.47 , pp. 649-653
    • Haan, J.1    Algra, P.R.2    Roos, R.A.3
  • 124
    • 0027761330 scopus 로고
    • Distribution of B/A4 protein and amyloid precursor protein in hereditary cerebral hemorrhage with amyloidosis-Dutch type and Alzheimer's disease
    • Rozemuller AJM, Roos RAC, Bots GTAM et al. Distribution of B/A4 protein and amyloid precursor protein in hereditary cerebral hemorrhage with amyloidosis-Dutch type and Alzheimer's disease. Am J Pathol 1993;142:1449-1457.
    • (1993) Am J Pathol , vol.142 , pp. 1449-1457
    • Rozemuller, A.J.M.1    Roos, R.A.C.2    Bots, G.T.A.M.3
  • 125
    • 0024504095 scopus 로고
    • Stroke in Icelandic patients with hereditary amyloid angiopathy is related to a mutation in the cystatin C gene, an inhibitor of cysteine proteases
    • Levy E, Lopez OC, Ghiso J et al. Stroke in Icelandic patients with hereditary amyloid angiopathy is related to a mutation in the cystatin C gene, an inhibitor of cysteine proteases. J Exp Med 1989;169:1771-1778.
    • (1989) J Exp Med , vol.169 , pp. 1771-1778
    • Levy, E.1    Lopez, O.C.2    Ghiso, J.3
  • 126
    • 0027210445 scopus 로고
    • Cystatin C (CST3), the candidate gene for hereditary cystatin C amyloid angiography (HC-CAA), and other members of the cystatin gene family are clustered on chromosome 20p11.2
    • Schnittger S, Rao W, Abrahamson M, Hansmann I. Cystatin C (CST3), the candidate gene for hereditary cystatin C amyloid angiography (HC-CAA), and other members of the cystatin gene family are clustered on chromosome 20p11.2 Genomics 1993;16:50-55.
    • (1993) Genomics , vol.16 , pp. 50-55
    • Schnittger, S.1    Rao, W.2    Abrahamson, M.3    Hansmann, I.4
  • 127
    • 0026659436 scopus 로고
    • Alzheimer's disease and hereditary cerebral hemorrhage with amyloidosis-Dutch type share a decrease in cerebrospinal fluid levels of amyloid beta-protein precursor
    • Van Nostrand W, Wagner SL, Haan J et al. Alzheimer's disease and hereditary cerebral hemorrhage with amyloidosis-Dutch type share a decrease in cerebrospinal fluid levels of amyloid beta-protein precursor. Ann Neurol 1992;32:215-218.
    • (1992) Ann Neurol , vol.32 , pp. 215-218
    • Van Nostrand, W.1    Wagner, S.L.2    Haan, J.3
  • 128
    • 0029038881 scopus 로고
    • Cerebral infarction in Alzheimer's disease is associated with severe amyloid angiopathy and hypertension
    • Olichney JM, Hansen LA, Hofstetter R et al. Cerebral infarction in Alzheimer's disease is associated with severe amyloid angiopathy and hypertension. Arch Neurol 1995;52:702-708.
    • (1995) Arch Neurol , vol.52 , pp. 702-708
    • Olichney, J.M.1    Hansen, L.A.2    Hofstetter, R.3
  • 129
    • 0028991404 scopus 로고
    • Apolipoprotein E ∈4 and cerebral hemorrhage associated with amyloid angiopathy
    • Greenberg SM, Rebeck GW, Vonsattel JPG et al. Apolipoprotein E ∈4 and cerebral hemorrhage associated with amyloid angiopathy. Ann Neurol 1995;38:254-259.
    • (1995) Ann Neurol , vol.38 , pp. 254-259
    • Greenberg, S.M.1    Rebeck, G.W.2    Vonsattel, J.P.G.3
  • 130
    • 0025513814 scopus 로고
    • Genetics of cerebrovascular disease
    • Alberts MJ. Genetics of cerebrovascular disease. Stroke 1990;21 (suppl. III):127-130.
    • (1990) Stroke , vol.21 , Issue.3 SUPPL. , pp. 127-130
    • Alberts, M.J.1
  • 132
    • 0027226051 scopus 로고
    • Familial aggregation of stroke: The Framingham study
    • Kiely DK, Wolf PA, Cupples LA. Familial aggregation of stroke: The Framingham study. Stroke 1993;24:1366-1371.
    • (1993) Stroke , vol.24 , pp. 1366-1371
    • Kiely, D.K.1    Wolf, P.A.2    Cupples, L.A.3
  • 133
    • 0027933761 scopus 로고
    • The importance of family history in cerebrovascular disease
    • Graffagnino C, Gasecki AP, Doig GS, Hachinski VC. The importance of family history in cerebrovascular disease. Stroke 1994;25:1599-1604.
    • (1994) Stroke , vol.25 , pp. 1599-1604
    • Graffagnino, C.1    Gasecki, A.P.2    Doig, G.S.3    Hachinski, V.C.4
  • 134
    • 0022467805 scopus 로고
    • Family history of heart attack: A modifiable risk factor?
    • Khaw KT, Barrett CE. Family history of heart attack: A modifiable risk factor? Circulation 1986;74:239-244.
    • (1986) Circulation , vol.74 , pp. 239-244
    • Khaw, K.T.1    Barrett, C.E.2
  • 136
    • 0027512278 scopus 로고
    • Genetic and environmental influences on serum lipids in twins
    • Heller DA, de Faire U, Pedersen NL et al. Genetic and environmental influences on serum lipids in twins. N Engl J Med 1993;328:1150-1156.
    • (1993) N Engl J Med , vol.328 , pp. 1150-1156
    • Heller, D.A.1    De Faire, U.2    Pedersen, N.L.3
  • 137
    • 0028854789 scopus 로고
    • Education and occupation as risk factors for dementias of the Alzheimer and ischemic vascular type
    • Mortel KF, Meyer JS, Herod B, Thornby J. Education and occupation as risk factors for dementias of the Alzheimer and ischemic vascular type. Dementia 1995;6:55-62.
    • (1995) Dementia , vol.6 , pp. 55-62
    • Mortel, K.F.1    Meyer, J.S.2    Herod, B.3    Thornby, J.4
  • 138
    • 0028914970 scopus 로고
    • Prevalence of Alzheimer's disease and vascular dementia: Association with education. The Rotterdam study
    • Ott A, Breteler MMB, van Harskamp F et al. Prevalence of Alzheimer's disease and vascular dementia: Association with education. The Rotterdam study. Br Med J 1995;310:970-973.
    • (1995) Br Med J , vol.310 , pp. 970-973
    • Ott, A.1    Breteler, M.M.B.2    Van Harskamp, F.3
  • 139
    • 0026772380 scopus 로고
    • Socioeconomic status and health: How education, income, and occupation contribute to risk factors for cardiovascular disease
    • Winkleby MA, Jatulis DE, Frank E, Fortmann SP. Socioeconomic status and health: How education, income, and occupation contribute to risk factors for cardiovascular disease. Am J Public Health 1992;82:816-820.
    • (1992) Am J Public Health , vol.82 , pp. 816-820
    • Winkleby, M.A.1    Jatulis, D.E.2    Frank, E.3    Fortmann, S.P.4
  • 141
    • 0000290475 scopus 로고
    • Brain reserve capacity on symptom onset after brain injury: A formulation and review of evidence for threshold theory
    • Satz P. Brain reserve capacity on symptom onset after brain injury: A formulation and review of evidence for threshold theory. Neuropsychology 1993;7:273-295.
    • (1993) Neuropsychology , vol.7 , pp. 273-295
    • Satz, P.1
  • 142
    • 0025242640 scopus 로고
    • Cortical senile plaques in coronary artery disease, aging and Alzheimer's disease
    • Sparks DL, Hunsaker JC, Scheff SW et al.. Cortical senile plaques in coronary artery disease, aging and Alzheimer's disease. Neurobiol Aging 1990;11:601-607.
    • (1990) Neurobiol Aging , vol.11 , pp. 601-607
    • Sparks, D.L.1    Hunsaker, J.C.2    Scheff, S.W.3
  • 143
    • 0025775107 scopus 로고
    • Selective induction of Kunitz-type protease inhibitor domain-containing amyloid precursor protein mRNA after persistent focal ischemia in rat cerebral cortex
    • Abe K, Tanzi RE, Kogure K. Selective induction of Kunitz-type protease inhibitor domain-containing amyloid precursor protein mRNA after persistent focal ischemia in rat cerebral cortex. Neurosci Lett 1991;125:172-174.
    • (1991) Neurosci Lett , vol.125 , pp. 172-174
    • Abe, K.1    Tanzi, R.E.2    Kogure, K.3
  • 144
    • 0028941978 scopus 로고
    • Relation of coronary atherosclerosis and apolipoprotein E genotypes in Alzheimer patients
    • Kosunen O, Talasniemi S, Lehtovirta M et al. Relation of coronary atherosclerosis and apolipoprotein E genotypes in Alzheimer patients. Stroke 1995;26:743-748.
    • (1995) Stroke , vol.26 , pp. 743-748
    • Kosunen, O.1    Talasniemi, S.2    Lehtovirta, M.3
  • 145
    • 0028167816 scopus 로고
    • Apolipoprotein E ∈4 allele in Alzheimer's disease and vascular dementia
    • Frisoni GB, Calabresi L, Geroldi C et al. Apolipoprotein E ∈4 allele in Alzheimer's disease and vascular dementia. Dementia 1994;5:240-242.
    • (1994) Dementia , vol.5 , pp. 240-242
    • Frisoni, G.B.1    Calabresi, L.2    Geroldi, C.3
  • 146
    • 0027203749 scopus 로고
    • Apolipoprotein E genotype and Alzheimer's disease
    • Noguchi S, Murakami K, Yamada N. Apolipoprotein E genotype and Alzheimer's disease Lancet 1993;342:737.
    • (1993) Lancet , vol.342 , pp. 737
    • Noguchi, S.1    Murakami, K.2    Yamada, N.3
  • 147
    • 0026453496 scopus 로고
    • Lipoprotein and apolipoprotein profile in men with ischemic stroke. Role of lipoprotein(a), triglyceride-rich lipoproteins, and apolipoprotein E polymorphism
    • Pedro-Botet J, Senti M, Nogues X et al. Lipoprotein and apolipoprotein profile in men with ischemic stroke. Role of lipoprotein(a), triglyceride-rich lipoproteins, and apolipoprotein E polymorphism. Stroke 1992;23:1556-1562.
    • (1992) Stroke , vol.23 , pp. 1556-1562
    • Pedro-Botet, J.1    Senti, M.2    Nogues, X.3
  • 148
    • 0027178862 scopus 로고
    • Apolipoprotein E4 allele frequency, ischemic cerebrovascular disease, and Alzheimer's disease
    • Saunders AM, Roses AD. Apolipoprotein E4 allele frequency, ischemic cerebrovascular disease, and Alzheimer's disease Stroke 1993;24:1416.
    • (1993) Stroke , vol.24 , pp. 1416
    • Saunders, A.M.1    Roses, A.D.2
  • 149
    • 0027933984 scopus 로고
    • Apo E allele frequencies in Alzheimer's disease, Lewy body dementia, Alzheimer's disease with cerebrovascular disease and vascular dementia
    • Betard C, Robitaille Y, Gee M et al. Apo E allele frequencies in Alzheimer's disease, Lewy body dementia, Alzheimer's disease with cerebrovascular disease and vascular dementia. Neuroreport 1994;5:1893-1896.
    • (1994) Neuroreport , vol.5 , pp. 1893-1896
    • Betard, C.1    Robitaille, Y.2    Gee, M.3
  • 150
    • 0027315427 scopus 로고
    • Prevalence of apolipoprotein E phenotypes in ischemic cerebrovascular disease. A case control study
    • Couderc R, Mahieux F, Bailleul S et al. Prevalence of apolipoprotein E phenotypes in ischemic cerebrovascular disease. A case control study. Stroke 1993;24:661-664.
    • (1993) Stroke , vol.24 , pp. 661-664
    • Couderc, R.1    Mahieux, F.2    Bailleul, S.3


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