-
1
-
-
0025279872
-
Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection
-
Miller DG, Adam MA, Miller AD: Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection. Mol Cell Biol 10:4239, 1990
-
(1990)
Mol Cell Biol
, vol.10
, pp. 4239
-
-
Miller, D.G.1
Adam, M.A.2
Miller, A.D.3
-
2
-
-
0028055281
-
Passage through mitosis is required for oncoretorviruses but not for the human immunodeficiency virus
-
Lewis PF, Emerman M: Passage through mitosis is required for oncoretorviruses but not for the human immunodeficiency virus. J Virol 68:510, 1994
-
(1994)
J Virol
, vol.68
, pp. 510
-
-
Lewis, P.F.1
Emerman, M.2
-
3
-
-
0027248755
-
Human cord blood cells as targets for gene transfer: Potential use in genetic therapies of severe combined immunodeficiency disease
-
Moritz T, Keller DC, Williams DA: Human cord blood cells as targets for gene transfer: Potential use in genetic therapies of severe combined immunodeficiency disease. J Exp Med 178:529, 1993
-
(1993)
J Exp Med
, vol.178
, pp. 529
-
-
Moritz, T.1
Keller, D.C.2
Williams, D.A.3
-
4
-
-
0027819175
-
Retroviral-mediated gene transfer into CD34-enriched human peripheral blood stem cells
-
Cassel A, Cottler-Fox M, Doren S, Dunbar CE: Retroviral-mediated gene transfer into CD34-enriched human peripheral blood stem cells. Exp Hematol 21:585, 1993
-
(1993)
Exp Hematol
, vol.21
, pp. 585
-
-
Cassel, A.1
Cottler-Fox, M.2
Doren, S.3
Dunbar, C.E.4
-
5
-
-
0028876039
-
The presence of an autologous marrow stromal cell layer increases glucocerebrosidase gene transduction of long -term culture initiating cells (LTCICs) from the bone marrow of a patient with Gaucher disease
-
Wells S, Malik P, Pensiero M, Kohn DB, Nolta JA: The presence of an autologous marrow stromal cell layer increases glucocerebrosidase gene transduction of long -term culture initiating cells (LTCICs) from the bone marrow of a patient with Gaucher disease. Gene Ther 2:512, 1995
-
(1995)
Gene Ther
, vol.2
, pp. 512
-
-
Wells, S.1
Malik, P.2
Pensiero, M.3
Kohn, D.B.4
Nolta, J.A.5
-
6
-
-
0026514847
-
Stromal support enhances cell-free retroviral vector transduction of human bone marrow long-term culture-initiating cells
-
Moore KA, Deisseroth AB, Reading CL, Williams DE, Belmont JW: Stromal support enhances cell-free retroviral vector transduction of human bone marrow long-term culture-initiating cells. Blood 79:1393, 1992
-
(1992)
Blood
, vol.79
, pp. 1393
-
-
Moore, K.A.1
Deisseroth, A.B.2
Reading, C.L.3
Williams, D.E.4
Belmont, J.W.5
-
8
-
-
0028176884
-
Bone marrow extracellular matrix molecules improve gene transfer into human hematopoietic cells via retroviral vectors
-
Moritz T, Patel VP, Williams DA: Bone marrow extracellular matrix molecules improve gene transfer into human hematopoietic cells via retroviral vectors. J Clin Invest 93:1451, 1994
-
(1994)
J Clin Invest
, vol.93
, pp. 1451
-
-
Moritz, T.1
Patel, V.P.2
Williams, D.A.3
-
9
-
-
0029055941
-
Analysis of optimal conditions for retroviral-mediated transduction of primitive human hematopoietic cells
-
Nolta JA, Smogorzewska EM, Kohn DB: Analysis of optimal conditions for retroviral-mediated transduction of primitive human hematopoietic cells. Blood 86:101, 1995
-
(1995)
Blood
, vol.86
, pp. 101
-
-
Nolta, J.A.1
Smogorzewska, E.M.2
Kohn, D.B.3
-
10
-
-
0027146421
-
Molecular cloning of a ligand for the flt3/flk2 tyrosine kinase receptor: A proliferative factor for primitive hematopoietic cells
-
Lyman SD, James L, Vanden BT, de Vries P, Brasel K, Gliniak B, Hollingsworth LT, Picha KS, Splett RR, Beckmann MP, McKenna HJ: Molecular cloning of a ligand for the flt3/flk2 tyrosine kinase receptor: A proliferative factor for primitive hematopoietic cells. Cell 75:1157, 1993
-
(1993)
Cell
, vol.75
, pp. 1157
-
-
Lyman, S.D.1
James, L.2
Vanden, B.T.3
De Vries, P.4
Brasel, K.5
Gliniak, B.6
Hollingsworth, L.T.7
Picha, K.S.8
Splett, R.R.9
Beckmann, M.P.10
McKenna, H.J.11
-
11
-
-
0029134556
-
Multi-level effects of flt3 ligand on human hematopoiesis: Expansion of putative stem cells and proliferation of granulomonocytic progenitors/ monocytic precursors
-
Gabbianelli M, Pelosi E, Montesoro E, Valtieri M, Luchetti L, Samoggia P, Vitelli L, Barberi T, Testa U, Lyman S, Peschle C: Multi-level effects of flt3 ligand on human hematopoiesis: Expansion of putative stem cells and proliferation of granulomonocytic progenitors/ monocytic precursors. Blood 86:1661, 1995
-
(1995)
Blood
, vol.86
, pp. 1661
-
-
Gabbianelli, M.1
Pelosi, E.2
Montesoro, E.3
Valtieri, M.4
Luchetti, L.5
Samoggia, P.6
Vitelli, L.7
Barberi, T.8
Testa, U.9
Lyman, S.10
Peschle, C.11
-
13
-
-
0029151332
-
Flt3 ligand stimulates/costimulates the growth of myeloid stem/ progenitor cells
-
Broxmeyer HE, Lu L, Cooper S, Ruggiere L, Li ZH, Lyman SD: Flt3 ligand stimulates/costimulates the growth of myeloid stem/ progenitor cells. Exp Hematol 23:1121, 1995
-
(1995)
Exp Hematol
, vol.23
, pp. 1121
-
-
Broxmeyer, H.E.1
Lu, L.2
Cooper, S.3
Ruggiere, L.4
Li, Z.H.5
Lyman, S.D.6
-
15
-
-
0025834275
-
Construction and properties of retrovirus packaging cells based on gibbon ape leukemia virus
-
Miller AD, Garcia JV, von Suhr N, Lynch CM, Wilson C, Eiden MV: Construction and properties of retrovirus packaging cells based on gibbon ape leukemia virus. J Virol 65:2220, 1994
-
(1994)
J Virol
, vol.65
, pp. 2220
-
-
Miller, A.D.1
Garcia, J.V.2
Von Suhr, N.3
Lynch, C.M.4
Wilson, C.5
Eiden, M.V.6
-
16
-
-
0028325345
-
Sustained human hematopoiesis in immunodeficient mice by co-transplantation of marrow stroma expressing human IL-3: Analysis of gene transduction of long-lived progenitors
-
Nolta JA, Hanley MB, Kohn DB: Sustained human hematopoiesis in immunodeficient mice by co-transplantation of marrow stroma expressing human IL-3: Analysis of gene transduction of long-lived progenitors. Blood 83:3041, 1994
-
(1994)
Blood
, vol.83
, pp. 3041
-
-
Nolta, J.A.1
Hanley, M.B.2
Kohn, D.B.3
-
17
-
-
0029913896
-
Transduction of pluripotent human hematopoietic stem cells demonstrated by clonal analysis after engraftment in immune-deficient mice
-
Nolta JA, Dao MA, Wells S, Smogorzewska EM, Kohn DB: Transduction of pluripotent human hematopoietic stem cells demonstrated by clonal analysis after engraftment in immune-deficient mice. Proc Natl Acad Sci USA 93:2414, 1996
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 2414
-
-
Nolta, J.A.1
Dao, M.A.2
Wells, S.3
Smogorzewska, E.M.4
Kohn, D.B.5
-
18
-
-
0026779725
-
Retroviral-mediated transfer of the human glucocerebrosidase gene into cultured Gaucher bone marrow
-
Nolta JA, Yu XJ, Kohn DB: Retroviral-mediated transfer of the human glucocerebrosidase gene into cultured Gaucher bone marrow. J Clin Invest 90:342, 1992
-
(1992)
J Clin Invest
, vol.90
, pp. 342
-
-
Nolta, J.A.1
Yu, X.J.2
Kohn, D.B.3
-
19
-
-
0028815676
-
Multiple modifications in cis-elements of the LTR of retroviral vectors lead to increased expression and decreased DNA methylation in embryonic carcinoma (EC) cells
-
Challita PM, Skelton D, El-Khoueiry A, Yu, XJ, Weinberg KI, Kohn DB: Multiple modifications in cis-elements of the LTR of retroviral vectors lead to increased expression and decreased DNA methylation in embryonic carcinoma (EC) cells. J Virol 69:748, 1995
-
(1995)
J Virol
, vol.69
, pp. 748
-
-
Challita, P.M.1
Skelton, D.2
El-Khoueiry, A.3
Yu, X.J.4
Weinberg, K.I.5
Kohn, D.B.6
-
20
-
-
0027431409
-
Growth factors increase amphotropic retrovirus binding to human CD34 positive bone marrow progenitor cells
-
Crooks GM, Kohn DB: Growth factors increase amphotropic retrovirus binding to human CD34 positive bone marrow progenitor cells. Blood 82:3290, 1993
-
(1993)
Blood
, vol.82
, pp. 3290
-
-
Crooks, G.M.1
Kohn, D.B.2
-
21
-
-
0024460181
-
Improved retroviral vectors for gene transfer and expression
-
Miller AD, Rosman GJ: Improved retroviral vectors for gene transfer and expression. Biotechniques 7:980, 1989
-
(1989)
Biotechniques
, vol.7
, pp. 980
-
-
Miller, A.D.1
Rosman, G.J.2
-
22
-
-
0028263529
-
Direct demonstration that autologous bone marrow transplantation for solid tumors can return a multiplicity of tumorigenic cells
-
Rill DR, Santana VM, Roberts WM, Nilson T, Krance RA, Heslop HE, Moen RC, Ihle JN, Brenner MK: Direct demonstration that autologous bone marrow transplantation for solid tumors can return a multiplicity of tumorigenic cells. Blood 84:380, 1994
-
(1994)
Blood
, vol.84
, pp. 380
-
-
Rill, D.R.1
Santana, V.M.2
Roberts, W.M.3
Nilson, T.4
Krance, R.A.5
Heslop, H.E.6
Moen, R.C.7
Ihle, J.N.8
Brenner, M.K.9
-
24
-
-
0025176833
-
Clonal and systemic analysis of long-term hematopoiesis in the mouse
-
Jordan CT, Lemsischka IR: Clonal and systemic analysis of long-term hematopoiesis in the mouse. Genes Dev 4:220, 1990
-
(1990)
Genes Dev
, vol.4
, pp. 220
-
-
Jordan, C.T.1
Lemsischka, I.R.2
-
25
-
-
0022365333
-
Expression of a foreign gene in myeloid and lymphoid cells derived from multipotent hematopoietic precursors
-
Keller G, Paige C, Gilboa E, Wagner EF: Expression of a foreign gene in myeloid and lymphoid cells derived from multipotent hematopoietic precursors. Nature 318:149, 1985
-
(1985)
Nature
, vol.318
, pp. 149
-
-
Keller, G.1
Paige, C.2
Gilboa, E.3
Wagner, E.F.4
-
26
-
-
0022366075
-
Gene expression in mice after high efficiency retroviral-mediated gene transfer
-
Eglitis MA, Kantoff P, Gilboa E, Anderson WF: Gene expression in mice after high efficiency retroviral-mediated gene transfer. Science 230:1395, 1985
-
(1985)
Science
, vol.230
, pp. 1395
-
-
Eglitis, M.A.1
Kantoff, P.2
Gilboa, E.3
Anderson, W.F.4
-
27
-
-
0024584243
-
Novel use of polymerase chain reaction to amplify cellular DNA adjacent to an integrated provirus
-
Silver J, Keerikatte V: Novel use of polymerase chain reaction to amplify cellular DNA adjacent to an integrated provirus. J Virol 63:1924, 1989
-
(1989)
J Virol
, vol.63
, pp. 1924
-
-
Silver, J.1
Keerikatte, V.2
-
29
-
-
0022375905
-
Normal cycling patterns of hematopoietic stem cell subpopulations: An assay using long-term in vivo BrdU infusion
-
Pietrzyk ME, Priestley GV, Wolf NS: Normal cycling patterns of hematopoietic stem cell subpopulations: An assay using long-term in vivo BrdU infusion. Blood 66:1460, 1985
-
(1985)
Blood
, vol.66
, pp. 1460
-
-
Pietrzyk, M.E.1
Priestley, G.V.2
Wolf, N.S.3
-
30
-
-
0025880646
-
Mechanisms that regulate the cell cycle status of very primitive hematopoietic cells in long-term human marrow cultures. II. Analysis of positive and negative regulators produced by stromal cells within the adherent layer
-
Eaves CJ, Cashman JD, Kay RJ, Dougherty GJ, Otsuka T, Gaboury LA. Hogge DE, Lansdorp PM, Eaves AC, Humphries RK: Mechanisms that regulate the cell cycle status of very primitive hematopoietic cells in long-term human marrow cultures. II. Analysis of positive and negative regulators produced by stromal cells within the adherent layer. Blood 78:110, 1991
-
(1991)
Blood
, vol.78
, pp. 110
-
-
Eaves, C.J.1
Cashman, J.D.2
Kay, R.J.3
Dougherty, G.J.4
Otsuka, T.5
Gaboury, L.A.6
Hogge, D.E.7
Lansdorp, P.M.8
Eaves, A.C.9
Humphries, R.K.10
-
31
-
-
0028966584
-
Functional isolation and characterization of human hematopoietic stem cells
-
Berardi AC, Wang A, Levine JD, Lopez P, Scadden DT: Functional isolation and characterization of human hematopoietic stem cells. Science 267:104, 1995
-
(1995)
Science
, vol.267
, pp. 104
-
-
Berardi, A.C.1
Wang, A.2
Levine, J.D.3
Lopez, P.4
Scadden, D.T.5
-
33
-
-
0024380889
-
Combination of interleukins 3 and 6 preserves stem cell function in culture and enhances retrovirus-mediated gene transfer into hematopoietic stem cells
-
Bodine DM, Karlsson S, Neinhuis AW: Combination of interleukins 3 and 6 preserves stem cell function in culture and enhances retrovirus-mediated gene transfer into hematopoietic stem cells. Proc Natl Acad Sci USA 86:8897, 1986
-
(1986)
Proc Natl Acad Sci USA
, vol.86
, pp. 8897
-
-
Bodine, D.M.1
Karlsson, S.2
Neinhuis, A.W.3
-
34
-
-
0025490017
-
Comparison of the effects of growth factors on retroviral vector-mediated gene transfer and the proliferative status of human hematopoietic progenitor cells
-
Nolta JA, Kohn DB: Comparison of the effects of growth factors on retroviral vector-mediated gene transfer and the proliferative status of human hematopoietic progenitor cells. Hum Gene Ther 1:257, 1990
-
(1990)
Hum Gene Ther
, vol.1
, pp. 257
-
-
Nolta, J.A.1
Kohn, D.B.2
-
35
-
-
9344231135
-
A chymotryptic fragment of fibronectin (FN 30/35) increases gene transfer efficiency via colocalization of target cells and retroviral vectors
-
Moritz T, Dutt P, Hanenberg H, Xiao X, Ryder J, Carstanien D, Patel V, Vik T, Williams DA: A chymotryptic fragment of fibronectin (FN 30/35) increases gene transfer efficiency via colocalization of target cells and retroviral vectors. Exp Hematol 23:699a, 1995
-
(1995)
Exp Hematol
, vol.23
-
-
Moritz, T.1
Dutt, P.2
Hanenberg, H.3
Xiao, X.4
Ryder, J.5
Carstanien, D.6
Patel, V.7
Vik, T.8
Williams, D.A.9
-
36
-
-
0028318788
-
Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of hematopoietic stem cells and is encoded by variant RNAs
-
Hannum C, Culpepper J, Campbell D, Lee F: Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of hematopoietic stem cells and is encoded by variant RNAs. Nature 368:643, 1994
-
(1994)
Nature
, vol.368
, pp. 643
-
-
Hannum, C.1
Culpepper, J.2
Campbell, D.3
Lee, F.4
-
37
-
-
0028923125
-
The Flt3 ligand potently and directly stimulates the growth and expansion of primitive murine bone marrow progenitor cells in vitro: Synergistic interactions with interleukin (IL) 11, IL-12, and other hematopoietic growth factors
-
Jacobsen SW, Okkenhaug C, Myklebust J, Veiby OP, Lyman SD: The Flt3 ligand potently and directly stimulates the growth and expansion of primitive murine bone marrow progenitor cells in vitro: Synergistic interactions with interleukin (IL) 11, IL-12, and other hematopoietic growth factors. J Exp Med 181:1357, 1995
-
(1995)
J Exp Med
, vol.181
, pp. 1357
-
-
Jacobsen, S.W.1
Okkenhaug, C.2
Myklebust, J.3
Veiby, O.P.4
Lyman, S.D.5
-
38
-
-
0029006853
-
FLT3/FLK2 ligand promotes the growth of murine stem cells and the expansion of colony-forming cells and spleen colony-forming units
-
Hudak S, Hunte B, Culpepper J, Menon S, Hannum C, Thompson-Snipes L, Rennick D: FLT3/FLK2 ligand promotes the growth of murine stem cells and the expansion of colony-forming cells and spleen colony-forming units. Blood 85:2747, 1994
-
(1994)
Blood
, vol.85
, pp. 2747
-
-
Hudak, S.1
Hunte, B.2
Culpepper, J.3
Menon, S.4
Hannum, C.5
Thompson-Snipes, L.6
Rennick, D.7
-
39
-
-
0027955112
-
+ human bone marrow cells and is involved in the proliferation of early stem/ progenitor cells
-
+ human bone marrow cells and is involved in the proliferation of early stem/ progenitor cells. Proc Natl Acad Sci USA 91:459, 1994
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 459
-
-
Small, D.1
Levenstein, M.2
Kim, E.3
Carow, C.4
Amin, S.5
Rockwell, P.6
Witte, L.7
Burrow, C.8
Ratajczak, M.Z.9
Gewirtz, A.M.10
Civin, C.11
-
40
-
-
0025944679
-
Leukemia inhibitory factor improves survival of retroviral vector-infected hematopoietic stem cells in vitro, allowing efficient long-term expression of vector-encoded human adenosine deaminase in vivo
-
Fletcher FA, Moore KA, Ashkenazi M, De Vries P, Overbeek PA, Williams DE, Belmont JW: Leukemia inhibitory factor improves survival of retroviral vector-infected hematopoietic stem cells in vitro, allowing efficient long-term expression of vector-encoded human adenosine deaminase in vivo. J Exp Med 174:837, 1991
-
(1991)
J Exp Med
, vol.174
, pp. 837
-
-
Fletcher, F.A.1
Moore, K.A.2
Ashkenazi, M.3
De Vries, P.4
Overbeek, P.A.5
Williams, D.E.6
Belmont, J.W.7
-
41
-
-
0028864561
-
Engraftment of gene-modified umbilical cord blood cells in neonates with adenosine deaminase deficiency
-
Kohn DB, Weinberg KI, Nolta JA, Heiss LN, Lenarsky C, Crooks GM, Hanley ME, Annett GA, Brooks JS, El-Khoureiy A, Lawrence K, Wells S, Moen RC, Bastian J, Williams-Herman DE, Elder M, Wara D, Bowen T, Hershfeld MS, Mullen CA, Blaese RM, Parkman R: Engraftment of gene-modified umbilical cord blood cells in neonates with adenosine deaminase deficiency. Nat Med 1:1017, 1995
-
(1995)
Nat Med
, vol.1
, pp. 1017
-
-
Kohn, D.B.1
Weinberg, K.I.2
Nolta, J.A.3
Heiss, L.N.4
Lenarsky, C.5
Crooks, G.M.6
Hanley, M.E.7
Annett, G.A.8
Brooks, J.S.9
El-Khoureiy, A.10
Lawrence, K.11
Wells, S.12
Moen, R.C.13
Bastian, J.14
Williams-Herman, D.E.15
Elder, M.16
Wara, D.17
Bowen, T.18
Hershfeld, M.S.19
Mullen, C.A.20
Blaese, R.M.21
Parkman, R.22
more..
-
42
-
-
33748623131
-
Clonal diversity of vector-marked human hematopoietic progenitors recovered from long-term engrafted immune deficient mice
-
Dao MA, Nolta JA: Clonal diversity of vector-marked human hematopoietic progenitors recovered from long-term engrafted immune deficient mice. Exp Hematol 24:1056, 1996
-
(1996)
Exp Hematol
, vol.24
, pp. 1056
-
-
Dao, M.A.1
Nolta, J.A.2
-
43
-
-
23544473991
-
Comparison of retroviral transduction conditions for gene marking of adult peripheral blood or marrow-derived CD34+ cells in a clinical trial
-
abstr
-
Emmons RVB, Doren S, Hines K, Carter CS, Cottler-Fox M, O'Shaughnessy JA, Leitman SF, Cowan K, Dunbar CE: Comparison of retroviral transduction conditions for gene marking of adult peripheral blood or marrow-derived CD34+ cells in a clinical trial. Blood 86:940a, 1995 (abstr, suppl 1)
-
(1995)
Blood
, vol.86
, Issue.1 SUPPL.
-
-
Emmons, R.V.B.1
Doren, S.2
Hines, K.3
Carter, C.S.4
Cottler-Fox, M.5
O'Shaughnessy, J.A.6
Leitman, S.F.7
Cowan, K.8
Dunbar, C.E.9
-
44
-
-
85035174226
-
Retroviral-mediated gene transfer in multiple myeloma
-
abstr
-
Stewart AK, Prince HM, Sutherland DR, Cappe D, Nanji S, Dube ID: Retroviral-mediated gene transfer in multiple myeloma. Blood 86:965a, 1995 (abstr, suppl 1)
-
(1995)
Blood
, vol.86
, Issue.1 SUPPL.
-
-
Stewart, A.K.1
Prince, H.M.2
Sutherland, D.R.3
Cappe, D.4
Nanji, S.5
Dube, I.D.6
-
45
-
-
24544432079
-
Rapid neutrophil recovery in autologous transplants using cells that have been exposed to a multiple drug resistance (MDR-1) retroviral vector
-
abstr
-
Hanania EG, Kavanagh J, Giles RE, Kudelka A, Rahman Z, Holmes F, Hortobagyi G, Hamer J, Calvert L, Finnegan MB, Mante R, Ellerson D, Geisler D, Wang T, Su Y, Zu Z, Chen N, Berenson R, Heimfield S, Claxton D, Mechetner E, Holzmayer T, Mehra R, Cote R, Champlin R, Diesseroth AB: Rapid neutrophil recovery in autologous transplants using cells that have been exposed to a multiple drug resistance (MDR-1) retroviral vector. Blood 86:1833a, 1995 (abstr, suppl 1)
-
(1995)
Blood
, vol.86
, Issue.1 SUPPL.
-
-
Hanania, E.G.1
Kavanagh, J.2
Giles, R.E.3
Kudelka, A.4
Rahman, Z.5
Holmes, F.6
Hortobagyi, G.7
Hamer, J.8
Calvert, L.9
Finnegan, M.B.10
Mante, R.11
Ellerson, D.12
Geisler, D.13
Wang, T.14
Su, Y.15
Zu, Z.16
Chen, N.17
Berenson, R.18
Heimfield, S.19
Claxton, D.20
Mechetner, E.21
Holzmayer, T.22
Mehra, R.23
Cote, R.24
Champlin, R.25
Diesseroth, A.B.26
more..
-
46
-
-
23544482125
-
Preparation of autologous marrow stromal cells for clinical human gene therapy trials
-
Hines KA, Cottler-Fox M, Doren S, Carter CS, Dunbar C: Preparation of autologous marrow stromal cells for clinical human gene therapy trials. J Hematother 4:226a, 1995
-
(1995)
J Hematother
, vol.4
-
-
Hines, K.A.1
Cottler-Fox, M.2
Doren, S.3
Carter, C.S.4
Dunbar, C.5
|