High-level gene transfer to cord blood progenitors using gibbon ape leukemia virus pseudotype retroviral vectors and an improved clinically applicable protocol

Human Gene Therapy

Volumn 9, Issue 2, 1998, Pages 225-234

  Movassagh, Mojgan ^a   Desmyter, Christine ^a   Baillou, Claude ^a   Chapel Fernandes, Sylvie ^b   Guigon, Martine ^a   Klatzmann, David ^a   Lemoine, Francois M ^a  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b CENTRE DE GÉNÉTIQUE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; CD34 ANTIGEN; FIBRONECTIN; HEXADIMETHRINE BROMIDE; VIRUS ENVELOPE PROTEIN; VIRUS VECTOR;

ARTICLE; CELL ADHESION; CLINICAL PROTOCOL; GENE TRANSFER; GIBBON LEUKEMIA VIRUS; HEMATOPOIETIC STEM CELL; REPORTER GENE; UMBILICAL CORD BLOOD;

ALOCASIA MACRORRHIZOS; GIBBON APE LEUKEMIA VIRUS; HYLOBATES SP.; UNIDENTIFIED RETROVIRUS;

EID: 0032548402     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.1998.9.2-225     Document Type: Article

References (5)

1. BAHNSON, A.B., DUNIGAN, J.T., BAYSAL, B.E., MOHNEY, T., ATCHISON, R.W., NIMGAONKAR, M.T., BALL, E.D., and BARRANGER, J.A. (1995). Centrifugal enhancement of retroviral mediated gene transfer. J. Virol. Methods 54, 131-143.
2. BROXMEYER, H.E., HANGOC, G., COOPER, S., RIBEIRO, R.C., GRAVES, V., YODER, M., WAGNER, J.E., VADHAN-RAJ, S., BENNINGER, L., RUBINSTEIN, P., and BROUN, E.R. (1992). Growth characteristics and expansion of human umbilical cord blood and estimation of its potential for transplantation in adults. Proc. Natl. Acad. Sci. USA 89, 4109-4113.
3. BUNNEL, B.A., MUUL, M.L., DONAHUE, R.E., BLAESE, R.M., and MORGAN, R.A. (1995). High-efficiency retroviral-mediated gene transfer into human and nonhuman primate peripheral blood lymphocytes. Proc. Natl. Acad. Sci. USA 92, 7739-7743.
4. CHUCK, A.S., and PALSSON, B.O. (1996). Consistent and high rates of gene transfer can be obtained using flow-through transduction over a wide range of retroviral titers. Hum. Gene Ther. 7, 743-750.
5. CORNETTA, K., and ANDERSON, W.F. (1989). Protamine sulfate as an effective alternative to polybrene in retroviral-mediated gene-transfer: implications for human gene therapy. J. Virol. Methods 23, 187-194.