Efficient gene transfer in primitive CD34+/CD38(lo) human bone marrow cells reselected after long-term exposure to GALV-Pseudotyped retroviral vector

Human Gene Therapy

Volumn 8, Issue 17, 1997, Pages 2079-2086

  Glimm, Hanno ^a,c   Kiem, Hans Peter ^a   Darovsky, Boris ^a   Storb, Rainer ^a   Wolf, Jürgen ^b   Diehl, Volker ^b   Mertelsmann, Roland ^a   Von Kalle, Christof ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; CD38 ANTIGEN; VIRUS VECTOR;

ARTICLE; BONE MARROW CULTURE; CELL CULTURE; CELL CYCLE; GENE THERAPY; GENE TRANSFER; GIBBON LEUKEMIA VIRUS; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; NONHUMAN; RETROVIRUS;

EID: 0031581183     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.1997.8.17-2079     Document Type: Article

References (5)

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3. BERARDI, A.C., WANG, A., LEVINE, J.D., LOPEZ, P., and SCADDEN, D.T. (1995). Functional isolation and characterization of human hematopoietic stem cells. Science 267, 104-108.
4. BIENZLE, D., ABRAMS, O.A., KRUTH, S.A., ACKLAND, S.J., CARTER, R.F., DICK, J.E., JACOBS, R.M., KAMEL, R.S., and DUBE, I.D. (1994). Gene transfer into hematopoietic stem cells: long-term maintenance of in vitro activated progenitors without marrow ablation. Proc. Natl. Acad. Sci. USA 91, 350-354.
5. BODINE, D.M., MCDONAGH, K.T., SEIDEL, N.E., and NEINHUIS, A.W. (1990). Development of a high-titer retrovirus producer cell line and strategies for retrovirus-mediated gene transfer into rhesus monkey hematopoietic stem cells. Ann. N.Y. Acad. Sci. 612, 415-426.