Inhibition of human telomerase activity by peptide nucleic acids

Nature Biotechnology

Volumn 14, Issue 5, 1996, Pages

  Norton, James C ^a   Piatyszek, Mieczyslaw A ^b,c   Wright, Woodring E ^b   Shay, Jerry W ^b   Corey, David R ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c GERON CORPORATION   (United States)

Author keywords

Oligonucleotide; Phosphorothioate; PNA; Telomerase

Indexed keywords

ENZYME INHIBITOR; NUCLEIC ACID; OLIGOMER; OLIGONUCLEOTIDE; PHOSPHOROTHIOIC ACID; RIBONUCLEOPROTEIN; RNA; RNA DIRECTED RNA POLYMERASE;

ARTICLE; BINDING AFFINITY; CHEMICAL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; HUMAN; PRIORITY JOURNAL; TELOMERE;

BASE SEQUENCE; BIOTECHNOLOGY; DRUG DESIGN; ENZYME INHIBITORS; HUMANS; KINETICS; OLIGONUCLEOTIDES, ANTISENSE; PEPTIDES; TELOMERASE;

EID: 0029867408     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt0596-615     Document Type: Article

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