메뉴 건너뛰기




Volumn 11, Issue 5, 2000, Pages 347-360

Alterations of the AML1 transcription factor in human leukemia

Author keywords

Acute lymphoblastic leukemia; Acute myeloid leukemia; Chromosomal translocations; Histone deacetylase; Transcriptional repression

Indexed keywords

CORE BINDING FACTOR; HISTONE DEACETYLASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AML 1; UNCLASSIFIED DRUG;

EID: 0034489606     PISSN: 10849521     EISSN: None     Source Type: Journal    
DOI: 10.1006/scdb.2000.0183     Document Type: Article
Times cited : (52)

References (96)
  • 2
    • 0032822953 scopus 로고    scopus 로고
    • The AML1-ETO chimaeric transcription factor in acute myeloid leukaemia: Biology and clinical significance
    • (1999) Br J Haematol , vol.106 , pp. 296-308
    • Downing, J.R.1
  • 3
    • 0034696627 scopus 로고    scopus 로고
    • Role of the transcription factor AML-1 in acute leukemia and hematopoietic differentiation
    • (2000) Gene , vol.245 , pp. 223-235
    • Lutterbach, B.1    Hiebert, S.W.2
  • 6
    • 0026496547 scopus 로고
    • Transcriptionally active chimeric gene derived from the fusion of the AML1 gene and a novel gene on chromosome 8 in t(8;21) leukemic cells
    • published erratum appears in Cancer Genet Cytogenet 1993 Mar;66(1):81
    • (1992) Cancer Genet Cytogenet , vol.63 , pp. 81-88
    • Nisson, P.E.1    Watkins, P.C.2    Sacchi, N.3
  • 28
    • 8944230662 scopus 로고    scopus 로고
    • The extracellular signal-regulated kinase pathway phosphorylates AML1, an acute myeloid leukemia gene product, and potentially regulates its transactivation ability
    • (1996) Mol Cell Biol , vol.16 , pp. 3967-3979
    • Tanaka, T.1
  • 40
    • 0031724804 scopus 로고    scopus 로고
    • ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors
    • (1998) Mol Cell Biol , vol.18 , pp. 7176-7184
    • Lutterbach, B.1
  • 56
    • 9344257318 scopus 로고    scopus 로고
    • Persistence of multipotent progenitors expressing AML1/ETO transcripts in long-term remission patients with t(8;21) acute myelogenous leukemia
    • (1996) Blood , vol.87 , pp. 4789-4796
    • Miyamoto, T.1
  • 58
    • 85003534647 scopus 로고    scopus 로고
    • Preleukemic AML1/ETO-expressing hematopoietic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation; evidence for multistep leukemogenesis
    • Abstract
    • (1999) Blood , vol.94 , pp. 691a
    • Myamoto, T.1    Weissman, I.2    Akashi, K.3
  • 66
    • 17544388046 scopus 로고    scopus 로고
    • Frequency of prolonged remission duration after high-dose cytarabine intensification in acute myeloid leukemia varies by cytogenetic subtype
    • (1998) Cancer Res , vol.58 , pp. 4173-4179
    • Bloomfield, C.D.1
  • 67
    • 0032188805 scopus 로고    scopus 로고
    • The importance of diagnostic cytogenetics on outcome in AML: Analysis of 1,612 patients enrolled into the MRC AML 10 trial
    • (1998) Blood , vol.92 , pp. 2322-2333
    • Grimwade, D.1
  • 68
    • 9044231364 scopus 로고    scopus 로고
    • The t(12;21) translocation converts AML-1B from an activator to a repressor of transcription
    • (1996) Mol Cell Biol , vol.16 , pp. 1349-1355
    • Hiebert, S.W.1
  • 77
    • 0039844411 scopus 로고    scopus 로고
    • Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter
    • (1999) J Biol Chem , vol.274 , pp. 31577-31582
    • Hanai, J.1
  • 82
    • 0032830638 scopus 로고    scopus 로고
    • Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia
    • (1999) Nat Genet , vol.23 , pp. 166-175
    • Song, W.J.1
  • 84
    • 0030588487 scopus 로고    scopus 로고
    • The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo
    • (1996) Cell , vol.87 , pp. 697-708
    • Wang, Q.1
  • 91
    • 0033559746 scopus 로고    scopus 로고
    • Biallelic and heterozygous point mutations in the runt domain of the AML1/PEBP2alphaB gene associated with myeloblastic leukemias
    • (1999) Blood , vol.93 , pp. 1817-1824
    • Osato, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.