A large variety of alternatively spliced and differentially expressed mRNAs are encoded by the human acute myeloid leukemia gene AML1

DNA and Cell Biology

Volumn 15, Issue 3, 1996, Pages 175-185

  Levanon, D ^a   Bernstein, Y ^a   Negreanu, V ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID PROTEIN;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; CHROMOSOME 21; DNA BINDING; DNA FLANKING REGION; GENE EXPRESSION; HUMAN; HUMAN CELL; IN SITU HYBRIDIZATION; MITOGENESIS; PRIORITY JOURNAL; RNA SPLICING; RNA TRANSLATION;

EID: 0029876030     PISSN: 10445498     EISSN: None     Source Type: Journal    
DOI: 10.1089/dna.1996.15.175     Document Type: Article

References (5)

1. AVRAHAM, K.B., LEVANON, D., NEGREANU, V., BERNSTEIN, Y., GRONER, Y., COPELAND, N.G., and JENKINS, N.A. (1995). Mapping of the rant domain gene, Aml2, to the distal region of mouse chromosome 4. Genomics 25, 603-605.
2. BAE, S.-C., YAMAGUCHI-IWAI, Y., OGAWA, E., MARUYAMA, M., INUZUKA, M., KAGOSHIMA, H., SHIGESADA, K., SATAKE, M., and ITO, Y. (1993). Isolation of PEBP2αB cDNA representing the mouse homolog of human acute myeloid leukemia gene, AML1. Oncogene 8, 809-814.
3. BAE, S.-C., OGAWA, E., MARUYAMA, M., OKA, H., SATAKE, M., SHIGESADA, K., JENKINS, N.A., GILBERT, D.J., COPELAND, N.G., and ITO, Y. (1994). PEBP2αB/Mouse AML1 consists of multiple isoforms that possess differential transactivation potentials. Mol. Cell. Biol. 14, 3242-3252.
4. CACERES, J.F., STAMM, S., HELFMAN, D.M., and KRAINER, A.R. (1994). Regulation of alternative splicing in vivo by overexpression of antagonistic splicing factors. Science 265, 1706-1709.
5. ERICKSON, P., GAO, J., CHANG, K.-S., LOOK, T., WHISENANT, E., RAIMONDI. S., LASHER, R., TRUJILLO, J., ROWLEY, J., and DRABKIN, H. (1992). Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML/ETO, with similarity to drosophila segmentation gene, runt. Blood 80, 1825-1831.