High dosage expression of a zinc finger protein, Grt1, suppresses a mutant of fission yeast slp1+, a homolog of CDC20/p55CDC/Fizzy

Journal of Cell Science

Volumn 113, Issue 22, 2000, Pages 3989-3999

  Yamada, H Y ^a   Matsumoto, S ^a   Matsumoto, T ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Anaphase promoting complex (APC); Fission yeast; Mitosis; Slp1 CDC20; Zinc finger

Indexed keywords

AMINO ACID; ANAPHASE PROMOTING COMPLEX; CELL CYCLE PROTEIN; FUNGAL PROTEIN; PROTEIN P55; ZINC FINGER PROTEIN;

ANAPHASE; ARTICLE; CELL CYCLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; ENZYME SUBUNIT; FUNGUS MUTANT; GENE REPRESSION; METAPHASE; MITOSIS; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SCHIZOSACCHAROMYCES POMBE; SEQUENCE HOMOLOGY; SISTER CHROMATID; TEMPERATURE SENSITIVE MUTANT; TEMPERATURE SENSITIVITY;

AMINO ACID SEQUENCE; CARRIER PROTEINS; CELL CYCLE; CELL CYCLE PROTEINS; CONSENSUS SEQUENCE; FUNGAL PROTEINS; GENE DELETION; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SUPPRESSION, GENETIC; TEMPERATURE; ZINC FINGERS;

FUNGI; SCHIZOSACCHAROMYCES POMBE;

EID: 0034474177     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (72)

1. The spindle checkpoint
2. The multidrug resistance gene PDR1 from Saccharomyces cerevisiae
3. The S. pombe zfs1 gene is required to prevent septation if mitotic progression is inhibited
4. Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p
5. Zinc fingers: Gilt by association
6. The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase intitiation
7. Fission yeast Cut1 and Cut2 are essential for sister chromatid separation, concentrate along the metaphase spindle, and form large complexes
8. Cut2 proteolysis required for sister chromatid separation in fission yeast
9. Fission yeast Cut2 required for anaphase has two destruction boxes
10. Cerevisiae 26S protease mutants arrest cell division in G2/metaphase
11. Cyclin is degraded by the ubiquitin pathway
12. Defective mitosis due to a mutation in the gene for a fission yeast 26S protease subunit
13. + is defective in metaphase to anaphase transition
14. Genetic engineering of Schizosaccharomyces pombe: A system for gene disruption and replacement using the ura4 gene as s selectable marker
15. Schizosaccharomyces pombe
16. The use of cell division cycle mutants to investigate the control of microtubule distribution in the fission yeast Schizosaccharomyces pombe
17. Kinesin-related cut7 protein associates with mitotic and meiotic spindles in fission yeast
18. The spindle checkpoint
19. The Schizosaccharomyces pombe spindle checkpoint protein mad2p blocks anaphase and genetically interacts with the anaphase-promoting complex
20. Roles of ubiquitin-mediated proteolysis in cell cycle control
21. Methylated ubiquitin inhibits cyclin degradation in clam embryo extracts
22. + that encodes a nuclear scaffold-like protein blocks spindle elongation in mitotic anaphase
23. The NDA3 gene of fission yeast encodes b-tubulin: A cold sensitive nda3 mutation reversibly blocks spindle formation and chromosome movement in mitosis
24. Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor
25. Ubiquitin, proteasomes, and the regulation of intracellular protein degradation
26. Ubiquitin-dependent protein degradation
27. Budding yeast Cdc20: A target of the spindle checkpoint
28. Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast
29. APC-mediated proteolysis of Asel and the morphogenesis of the mitotic spindle
30. Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex and is involved in regulating anaphase onset and late mitotic events
31. The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2
32. Fission yeast Slp1: An effector of the Mad2- dependent spindle checkpoint
33. A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B
34. Fission yeast Ste9, a homolog of Hct1/Cdh1 and Fizzy-related, is a novel negative regulator of cell cycle progression during G1-phase
35. Primary structure of the Saccharomyces cerevisiae GAL4 gene
36. Zinc fingers are sticking together
37. A fission yeast homolog of CDC20/p55CDC/Fizzy is required for recovery from DNA damage and genetically interacts with p34cdc2
38. An introduction to molecular genetic analysis of the fission yeast Schizosaccharomyces pombe
39. Regulation of the APC and the exit from mitosis
40. The role of cyclin synthesis and degradation in the control of maturation promoting factor activity
41. SCF and APC: The Yin and Yang of cell cycle regulated proteolysis
42. The KEN box: An APC recognition signal distinct from the D box targeted by Cdh1
43. The regulation of Cdc20 proteolysis reveals a role for the APC components Cdc23 and Cdc27 during S phase and early mitosis
44. + gene to initiate anaphase
45. Yeast Hct1 is a regulator of Clb2 cyclin proteolysis
46. Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34
47. The CDC20 Gene Product of Saccharomyces cerevisiae, a beta-Transducin Homolog, Is Required for a Subset of Microtuble-Dependent Cellular Processes
48. The Polo-like kinase Cdc5p and the WD-repeat protein Cdc20/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae
49. Mitotic regulation of protein phosphatases by the fission yeast sds22 protein
50. The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis
51. ntf1 + encodes a 6-cysteine zinc finger-containing transcription factor that regulates the nmt1 promoter in fission yeast
52. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellurose sheets; procedure and some application
53. Proteolytic ratchets that control progression through mitosis
54. Diacylglycerol kinases in signal transduction
55. CDC20 and CDH1: A family of substrate-specific activators of APC-dependent proteolysis
56. A novel mammalian protein, p55CDC, present in dividing cells is associated with protein kinase activity and has homology to the Saccharomyces cerevisiae cell division cycle proteins Cdc20 and Cdc4
57. Cell cycle-regulated expression, phosphorylation, and degradation of p55Cdc. A mammalian homolog of CDC20/Fizzy/slp1
58. Mts4, a non-ATPase subunit of the 26 S protease in fission yeast is essential for mitosis and interacts directly with the ATPase subunit Mts2
59. Distinct subunit functions and cell cycle regulated phosphorylation of 20S APC/cyclosome required for anaphase in fission yeast
60. A WD-repeat protein controls the cell cycle and differentiation by negatively regulating Cdc2/B-type cyclin complexes
61. Pds1p, an inhibitor of anaphase in budding yeast, plays a critical role in the APC and checkpoint pathway(s)
62. The role of the destruction box and its neighbouring lysine residues in cyclin B for anaphase ubiquitin-dependent proteolysis in fission yeast: Defining the D-box receptor
63. 20S cyclosome complex formation and proteolytic activity inhibited by the cAMP/PKA pathway
64. Fission yeast APC/cyclosome subunits. Cut20/Apc4 and Cut23/Apc8, in regulating metaphase-anaphase progression and cellular stress responses
65. Fission yeast cut mutations revisited: Control of anaphase
66. Control of metaphase-anaphase progression by proteolysis: Cyclosome function regulated by the protein kinase A pathway, ubiquitination and localization
67. TPR proteins required for anaphase progression mediate ubiquitination of mitotic B-type cyclins in yeast
68. Identification of subunits of the anaphase-promoting complex of Saccharomyces cerevisiae
69. Mass spectrometric analysis of the anaphase-promoting complex from yeast: Identification of a subunit related to cullins
70. Control of Cyclin Ubiquitination by CDK-Regulated Binding of Hct1 to the Anaphase Promoting Complex
71. Whose end is destruction: Cell division and the anaphase-promoting complex