The S. pombe zfs1 gene is required to prevent septation if mitotic progression is inhibited

Journal of Cell Science

Volumn 112, Issue 18, 1999, Pages 3103-3114

  Beltraminelli, Nicola ^a   Murone, Maximilien ^a,b   Simanis, Viesturs ^a  

^a SWISS INST FOR EXP CANCER RESEARCH   (Switzerland)

^b GENENTECH INC   (United States)

Author keywords

Checkpoint; Cytokinesis; Mitosis; S. pombe; zfs1

Indexed keywords

CELL CYCLE PROTEIN; MESSENGER RNA; MUTANT PROTEIN; PHOSPHOTRANSFERASE;

ALLELE; ARTICLE; CELL CYCLE; CELL CYCLE G1 PHASE; CELL DIVISION; CHROMOSOME LOSS; CONTROLLED STUDY; CYTOKINESIS; ENZYME ACTIVITY; FUNGAL GENETICS; GENE DOSAGE; GENE FUNCTION; MITOSIS; MITOSIS SPINDLE; NONHUMAN; PRIORITY JOURNAL; SCHIZOSACCHAROMYCES POMBE; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; SUPPRESSOR GENE; TEMPERATURE SENSITIVE MUTANT;

ACTINS; CALCIUM-BINDING PROTEINS; CARRIER PROTEINS; CELL CYCLE PROTEINS; CELL DIVISION; FUNGAL PROTEINS; GENE DELETION; GENE EXPRESSION; GENES, FUNGAL; GENES, SUPPRESSOR; MITOSIS; MUTATION; NUCLEAR PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS; SIGNAL TRANSDUCTION;

SACCHAROMYCES CEREVISIAE; SACCHAROMYCES POMBE; SCHIZOSACCHAROMYCES POMBE;

EID: 0032876649     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (66)

1. Alexandru, G., Zachariae, W., Schleiffer. A., and Nasmyth K. (1999). Sister chromatid separation and chromosome re-duplication are regulated by different mechanisms in response to spindle damage. EMBO J. 18, 2707-2721.
2. Amon A. (1999). The spindle checkpoint. Curr. Opin. Genet. Dev. 9, 69-75.
3. Bachant J. B. and Elledge, S. J. (1999). Mitotic treasures in the nucleolus. Nature 398, 757-758.
4. Bahler, J. and Pringle, J. R. (1998). Pomlp, a fission yeast protein kinase that provides positional information for both polarized growth and cytokinesis. Genes Dev. 12, 1356-1370.
5. Balasubramanian, M. K., McCollum, D., Chang, L., Wong, K. C., Naqvi, N. I., He, X., Sazer, S. and Gould, K. L. (1998). Isolation and characterization of new fission yeast cytokinesis mutants. Genetics 149, 1265-1275.
6. Bernard P., Hardwick, K and Javerzat, J-P. (1998). Fission yeast bubl is a mitotic centromere protein essential for the spindle checkpoint and the preservation of correct ploidy through mitosis. J. Cell Biol. 143, 1775-1787.
7. Cerutti, L. and Simanis, V. (1999). Asymmetry of the spindle pole bodies and spg lp GAP segregation during mitosis in fission yeast. J. Cell Sci. 112, 2313-2321.
8. Chang, F., Woollard, A. and Nurse, P. (1996). Isolation and characterization of fission yeast mutants defective in the assembly and placement of the contractile actin ring. J. Cell Sci. 109, 131-142.
9. Charles, J. F., Jaspersen S. L., Tinker-Kulberg R. L., Hwang, L., Szidon, A., and Morgan D. O. (1998). The Polo-related kinase Cdc5 activates and is destroyed by the mitotic cyclin destruction machinery in S. cerevisiae. Curr. Biol. 8, 497-507.
10. Fankhauser, C. and Simanis, V. (1993). The Schizosaccharomyces pombe cdc14 gene is required for septum formation and can also inhibit nuclear division. Mol. Biol. Cell 4, 531-539.
11. cdc2 kinase activity and regulation of septum formation: a link between mitosis and cytokinesis? EMBO J. 12, 2697-2704.
12. Fankhauser, C., Reymond, A., Cerutti, L., Utzig, S., Hofmann, K. and Simanis, V. (1995). The S pombe cdc15 gene is a key element in the reorganization of F-actin at mitosis. Cell 82, 435-444.
13. Fesquet, D., Fitzpatrick, P. J., Johnson, A. L., Kramer, K. M., Toyn, J. H. and Johnston, L. H. (1999). A Bub2p-dependent spindle checkpoint pathway regulates the Dbf2p kinase in budding yeast. EMBO J. 18, 2424-2434.
14. Fraschini, R., Formenti, E., Lucchini, G. and Piatti, S. (1999) Budding yeast Bub2 is localized at spindle pole bodies and activates the mitotic checkpoint via a different pathway from Mad2. J. Cell Biol. 145, 979-991.
15. Furge, K. A., Wong, K., Armstrong, J., Balasubramanian, M. and Albright, C. F. (1998). Byr4 and Cdc16 form a two-component GTPase-activating protein for the Spg1 GTPase that controls septation in fission yeast. Curr. Biol. 8, 947-954.
16. Ghiara, J. B., Richardson, H. E., Sugimoto, K., Henze, M., Lew, D. J., Wittenberg, C. and Reed, S. I. ( 1991 ). A cyclin B homolog in S. cerevisiae: chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosis. Cell 65, 163-174.
17. Gould, K. L. and Simanis, V. (1997). The control of septum formation in fission yeast. Genes Dev. 11, 2939-2951.
18. Hagan, I. M. and Hyams, J. S. (1988). The use of cell division cycle mutants to investigate the control of microtubule distribution in the fission yeast Schizosaccharomyces pombe. J. Cell Sci. 89, 343-357.
19. Hardwick, K. G. and Murray, A. W. (1995). Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast. J. Cell Biol. 131, 709-720.
20. Hardwick, K. G., Weiss, E., Luca, F. C., Winey, M. and Murray, A. W. (1996). Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption. Science 273, 953-956.
21. Hardwick, K. G. (1998). The spindle checkpoint. Trends Genet. 14, 1-4.
22. Harlow, E. and Lane, D. (1988). Antibodies, A Laboratory Manual. Cold Spring Harbor Laboratory Press, New York.
23. He, X., Patterson, T. E. and Sazer, S. (1997). The S. pombe spindle checkpoint protein Mad2p blocks anaphase and genetically interacts with the APC. Proc. Nat. Acad. Sci. USA 94, 7965-7970.
24. He, X., Jones, M. H., Winey, M. and Sazer, S. (1998). mph1, a member of the Mps1-like family of dual specificity protein kinases, is required for the spindle checkpoint in S. pombe. J. Cell Sci. 111, 1635-1647.
25. + that encodes a nuclear scaffold-like protein blocks spindle elongation in mitotic anaphase. J. Cell Biol. 106, 1171-1183.
26. Hoheisel, J. D., Maier, E., Mott, R., McCarthy, L., Grigoriev, A. V., Schalkwyk, L. C., Nizetic, D., Francis, F. and Lehrach, H. (1993). High resolution cosmid and P1 maps spanning the 14 Mb genome of the fission yeast S. pombe. Cell 73, 109-120.
27. Hoyt, M. A., Totis, L. and Roberts, B. T. (1991). S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function. Cell 66, 507-517.
28. Hwang, L. H., Lau, L. F., Smith, D. L., Mistrot, C. A., Hardwick, K. G., Hwang, E. S., Amon, A. and Murray, A. W. (1998). Budding yeast Cdc20: a target of the spindle checkpoint. Science 279, 1041-1044.
29. Jaspersen., S. L. Charles, J. F. Tinker-Kulberg, R. L. and Morgan, D. O. (1998). A late mitotic regulatory network controlling cyclin destruction in S. cerevisiae. Mol. Biol. Cell. 9, 2803-2817.
30. Jwa, M. and Song, K. (1998). Byr4, a dosage-dependent regulator of cytokinesis in S. pombe, interacts with a possible small GTPase pathway including Spg1 and Cdc16. Mol Cells 8, 240-245.
31. + encoding a zinc-finger protein functions in the mating pheromone recognition pathway. Mol. Biol. Cell 6, 1185-1195.
32. + gene product couples S phase to START and mitosis. Cell 74, 371-382.
33. Kim, S. H., Lin, D. P., Matsumoto, S., Kitazono, A. and Matsumoto, T. (1998). Fission yeast Slp1: an effector of the Mad2-dependent spindle checkpoint. Science 279, 1045-1047.
34. Le Goff, X., Utzig, S. and Simanis, V. (1999). Controlling septation in Fission yeast: finding the middle, and timing it right. Curr. Genet. 35, 571-584.
35. Li, R. and Murray, A. W. (1991). Feedback control of mitosis in budding yeast. Cell 66, 519-531.
36. Li, X. and Cai, M. (1997). Inactivation of the cyclin-dependent kinase Cdc28 abrogates cell cycle arrest induced by DNA damage and disassembly of mitotic spindles in Saccharomyces cerevisiae. Mol. Cell Biol. 17, 2723-2734.
37. Li, R. (1999). Bifurcation of the mitotic checkpoint pathway in budding yeast. Proc. Nat. Acad. Sci. USA 96, 4989-4994.
38. Marks, J. and Hyams, J. S. (1985). Localisation of F-actin through the cell division cycle of Schizosaccharomyces pombe. Eur. J. Cell Biol.. 39, 27-32.
39. Minet, M., Nurse, P., Thuriaux, P. and Mitchison, J. M. (1979). Uncontrolled septation in a cell division cycle mutant of the fission yeast Schizosaccharomyces pombe. J. Bacteriol. 137, 440-446.
40. Minshull, J., Straight, A., Rudner, A. D., Dernburg, A. F., Belmont, A. and Murray, A. W. (1996). Protein phosphatase 2A regulates MPF activity and sister chromatid cohesion in budding yeast. Curr. Biol. 6, 1609-1620.
41. cdc2 protein kinase during mitosis. Cell 58, 361-372.
42. Moreno, S., Klar, A. and Nurse, P. (1991). Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Meth. Enzymol. 194, 795-823.
43. Murone, M. and Simanis, V. (1996). The fission yeast dma1 gene is a component of the spindle assembly checkpoint, required to prevent septum formation and premature exit from mitosis if spindle function is compromised. EMBO J. 15, 6605-6616.
44. Niwa, O., Matsumoto, T. and Yanagida M. (1986). Construction of a minichromosome by deletion and its mitotic and meiotic behaviour in fission yeast. Mol. Gen. Genet. 203, 397-405.
45. Nurse, P., Thuriaux, P. and Nasmyth, K. (1976). Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe. Mol. Gen. Genet. 146, 167-178.
46. Pangilinan, F. and Spencer, F. (1996). Abnormal kinetochore structure activates the spindle assembly checkpoint in budding yeast. Mol. Biol. Cell 7, 1195-1208.
47. Petersen, J., Nielsen, O., Egel, R. and Hagan, I. M. (1998). F-actin distribution and function during sexual differentiation in Schizosaccharomyces pombe. J. Cell Sci. 111, 867-876.
48. + functions as an inducer in the mitotic control of fission yeast. Cell 45, 145-53.
49. + a gene encoding a protein kinase homolog. Cell 49, 559-567.
50. Saka, Y., Sutani, T., Yamashita, Y., Saitoh, S., Takeuchi, M., Nakaseko, Y. and Yanagida, M. (1994). Fission yeast cut3 and cut14, members of a ubiquitous protein family, are required for chromosome condensation and segregation in mitosis. EMBO J. 13, 4938-4952.
51. Samejima, I., Matsumoto, T., Nakaseko, Y., Beach, D. and Yanagida, M. (1993). Identification of seven new cut genes involved in Schizosaccharomyces pombe mitosis. J. Cell Sci. 105, 135-143.
52. Sazer, S., and Sherwood, S. (1990). Mitochondrial growth and DNA synthesis occur in the absence of nuclear DNA replication in fission yeast. J. Cell Sci. 97, 509-516
53. Schmidt, S., Sohrmann, M., Hofmann, K., Woollard, A. and Simanis, V. (1997). The Spg1p GTPase is an essential, dosage-dependent inducer of septum formation in Schizosaccharomyces pombe. Genes Dev. 11, 1519-1534.
54. Schwab, M., Lutum, A. S. and Seufert, W. (1997). Yeast Hct1 is a regulator of Clb2 cyclin proteolysis. Cell 90, 683-693.
55. Shirayama, M., Zachariae, W., Ciosk, R. and Nasmyth, K. (1998). The Polo-like kinase Cdc5p and the WD-repeat protein Cdc20p/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae. EMBO J. 17, 1336-1349.
56. Shou, W., Seol, J. H., Shevchenko, A., Baskerville, C., Moazed, D., Chen, Z. W. S., Jang, J., Shevchenko, A., Charbonneau, H. and Deshaies, R. J. (1999). Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdcl4 from nucleolar RENT complex. Cell 97, 233-244.
57. Song, K., Mach, K. E., Chen, C. Y., Reynolds, T. and Albright, C. F. (1996). A novel suppressor of ras1 in fission yeast, byr4, is a dosage-dependent inhibitor of cytokinesis. J. Cell Biol. 133, 1307-1319
58. Sohrmann, M., Fankhauser, C., Brodbeck, C. and Simanis, V. (1996). The dmf1/mid1 gene is essential for correct positioning of the division septum in fission yeast. Genes Dev. 10, 2707-2719.
59. Straight, A. F., Shou, W., Dowd, G. J., Turck, C. W., Deshaies, R. J., Johnson, A. D. and Moazed, D. (1999). Net1, a Sir2-associated nucleolar protein required for rDNA silencing and nucleolar integrity. Cell 97, 245-256.
60. Umesono, K., Toda, T., Hayashi, S. and Yanagida, M. (1983). Cell division cycle genes nda2 and nda3 of the fission yeast Schizosaccharomyces pombe control microtubular organization and sensitivity to anti-mitotic benzimidazole compounds. J. Mol. Biol. 168, 271-284.
61. Visintin, R., Prinz, S. and Amon, A. (1997). CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis. Science 278, 460-463.
62. Visintin R., Craig, K., Hwang, E. S.,. Prinz, S., Tyers, M., and Amon A. (1998). The phosphatase cdc14 triggers mitotic exit by reversal of cdk-dependent phosphorylation. Mol. Cell 2, 709-718.
63. Visintin R., Hwang, E. S. and Amon, A. (1999). Cfi1 prevents premature exit from mitosis by anchoring cdc14 phosphatase in the nucleolus. Nature 398, 818-824.
64. Wang, Y. and Burke, D. J. (1997). Cdc55p, the B-type regulatory subunit of protein phosphatase 2A, has multiple functions in mitosis and is required for the kinetochore/spindle checkpoint in Saccharomyces cerevisiae. Mol. Cell Biol. 17, 620-626.
65. Weiss, E. and Winey, M. (1996). The Saccharomyces cerevisiae spindle pole body duplication gene MPS1 is part of a mitotic checkpoint. J. Cell Biol. 132, 111-123.
66. Woods, A., Sherwin, T., Sasse, R., MacRae, T. H., Baines, A. J. and Gull, K. (1989). Definition of individual components within the cytoskeleton of Trypanosoma brucei by a library of monoclonal antibodies. J. Cell Sci. 93, 491-500.