Fission yeast Cut2 required for anaphase has two destruction boxes

EMBO Journal

Volumn 16, Issue 19, 1997, Pages 5977-5987

  Funabiki, Hironori ^a,b   Yamano, Hiroyuki ^c   Nagao, Koji ^a   Tanaka, Hirofumi ^d   Yasuda, Hideyo ^d   Hunt, Tim ^c   Yanagida, Mitsuhiro ^a  

^a KYOTO UNIVERSITY   (Japan)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^d TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

Anaphase; APC cyclosome; Cyclin; Destruction box; Mitosis

Indexed keywords

CELL EXTRACT; CYCLINE; FUNGAL PROTEIN; UBIQUITIN;

AMINO TERMINAL SEQUENCE; ANAPHASE; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; FUNGAL GENETICS; GENE MUTATION; HELA CELL; INTERPHASE; METAPHASE; MITOSIS SPINDLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SCHIZOSACCHAROMYCES POMBE; SISTER CHROMATID; XENOPUS;

ANAPHASE; ANIMALS; CELL CYCLE PROTEINS; CYCLIN B; DNA, FUNGAL; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; FUNGAL PROTEINS; G1 PHASE; METAPHASE; MUTAGENESIS; PHOSPHORYLATION; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS; SISTER CHROMATID EXCHANGE; UBIQUITINS; XENOPUS;

SCHIZOSACCHAROMYCES POMBE;

EID: 0030824368     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.19.5977     Document Type: Article

References (48)

1. Aristarkhov,A., Eytan,E., Moghe,A., Admon,A., Hershko,A. and Ruderman,J.V. (1996) E2-C, a cyclin-selective ubiquitin carrier protein required for the destruction of mitotic cyclins. Proc. Natl Acad. Sci. USA, 93, 4294-4299.
2. Basi,G., Schmid,E. and Maundrell,K. (1993) TATA box mutations in the Schizosaccharomyces pombe nmt1 promoter affect transcription efficiency but not the transcription start point or thiamine repressibility. Gene, 123, 131-136.
3. Cohen-Fix,A., Peters,J.-M., Kirschner,M.W. and Koshland,D. (1996) Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p. Genes Dev., 15, 3081-3093.
4. Funabiki,H., Kumada,K. and Yanagida,M. (1996a) Fission yeast Cut1 and Cut2 are essential for sister chromatid separation, concentrate along the metaphase spindle and form large complexes. EMBO J., 15, 6617-6628.
5. Funabiki,H., Yamano,H., Kumada,K., Nagao,K., Hunt,T. and Yanagida,M. (1996b) Cut2 proteolysis required for sister-chromatid separation in fission yeast. Nature, 381, 438-441.
6. Ghisiain,M., Udvardy,A. and Mann,C. (1993) S.cerevisiae 26S protease mutants arrest cell division in G2/metaphase. Nature, 366, 358-361.
7. Glotzer,M., Murray,A.W. and Kirschner,M.W. (1991) Cyclin is degraded by the ubiquitin pathway. Nature, 349, 132-138.
8. Gordon,C., McGurk,G., Dillon,P., Rosen,C. and Hastie,N.D. (1993) Defective mitosis due to a mutation in the gene for a fission yeast 26S protease subunit. Nature, 366, 355-357.
9. + gene as a selectable marker. Mol. Gen. Genet., 215, 81-86.
10. Hagan,I. and Hyams,J.S. (1988) The use of cell division cycle mutants to investigate the control of microtubule distribution in the fission yeast Schizosaccharomyces pombe. J. Cell Sci., 89, 343-357.
11. + associates with the fission yeast spindle pole body and is essential for viability. J. Cell Biol., 129, 1033-1047.
12. Hershko,A. (1996) Lessons from the discovery of the ubiquitin system. Trends Biochem. Sci., 21, 445-449.
13. Hirano,T., Funahashi,S., Uemura,T. and Yanagida,M. (1986) Isolation and characterization of Schizosaccharomyces pombe cut mutants that block nuclear division but not cytokinesis. EMBO J., 5, 2973-2979.
14. + that encodes a nuclear scaffold-like protein blocks spindle elongation in mitotic anaphase. J Cell Biol., 106, 1171-1183.
15. Holloway,S., Glotzer,M., King,R.W. and Murray,A.W. (1993) Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor. Cell, 73, 1393-1402.
16. Honda,R., Tanaka,H., Ohba,Y. and Yasuda,H. (1995) Mouse p87weel kinase is regulated by M-phase specific phosphorylation. Chromosome Res., 3, 300-308.
17. Hunt,T., Luca,F.C. and RudermanJ.V. (1992) The requirements for protein synthesis and degradation, and the control of destruction of cyclins A and B in the meiotic and mitotic cell cycles of the clam embryo. J. Cell Biol. 116, 707-724.
18. Irniger,S., Piatti,S. and Nasmyth,K. (1995) Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast. Cell, 81, 269-278.
19. Juang,Y.L., Huang,J., Peters,J.M., McLaughlin,M.E., Tai,C.Y. and Pellman,D. (1997) APC-mediated proteolysis of Ase1 and the morphogenesis of the mitotic spindle. Science, 275, 1311-1314.
20. King,R.W., Peters,J.-M., Tugendreich,S., Rolfe,M., Hieter,P. and Kirschner,M.W. (1995) A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B. Cell, 81, 279-288.
21. King,R.W., Glotzer,M. and Kirschner,M.W. (1996) Mutagenic analysis of the destruction signal of mitotic cyclins and structural characterization of ubiquitinated intermediates. Mol. Biol. Cell, 7, 1343-1357.
22. Klotzbücher,A., Stewart,E., Harrison,D. and Hunt,T. (1996) The 'destruction box' of cyclin A allows B-type cycling to be ubiquitinated, but not efficiently destroyed. EMBO J., 15, 3053-3064.
23. Lanker,S., Valdivieso,M.H. and Wittenberg,C. (1996) Rapid degradation of the G1 cyclin Cln2 induced by CDK-dependent phosphorylation. Science, 271, 1597-1601.
24. Maundrell,K. (1990) nmt1 of fission yeast. J. Biol. Chem., 265, 10857-10864.
25. Mitchison,J.M. (1970) Physiological and cytological methods for Schizosaccharomyces pombe. Methods Cell Physiol., 4, 131-165.
26. Murray,A.W., Solomon,M. and Kirschner,M.W. (1989) The role of cyclin synthesis and degradation in the control of maturation promoting factor activity. Nature, 339, 289-286.
27. Nurse,P., Thuriaux,P. and Nasmyth,K. (1976) Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe. Mol Gen. Genet., 146, 167-178.
28. O'Donnell,K.L., Osmani,A.H., Osmani,S.A. and Morris,N.R. (1991) bimA encodes a member of the tetratricopeptide repeat family of proteins and is required for the completion of mitosis in Aspergillus nidulans. J. Cell Sci., 99, 711-719.
29. Peters,J.-M., King,R.C., Höög,C. and Kirschner,M.W. (1996) Identification of BIME as a subunit of the anaphase-promoting complex. Science, 274, 1199-1201.
30. Rimmington,G., Dalby,B. and Glover,D.M. (1996) Expression of N-terminally truncated cyclin B in the Drosophila larval brain leads to mitotic delay at late anaphase. J. Cell Sci., 107, 2729-2738.
31. +. Cell, 74, 383-393.
32. + gene to initiate anaphase. J. Ceil Biol., 127, 1665-1670.
33. Shiozaki,K. and Yanagida,M. (1992) Functional dissection of the phosphorylated termini of fission yeast DNA topoisomerase II. J. Cell Biol., 119, 1023-1036.
34. Sigrist,J., Jacobs,H., Stramann,R. and Lehner,C.F. (1995) Exit from mitosis is regulated by Drosophila fizzy and the sequential destruction of cyclins A, B and B3. EMBO J., 14, 4827-4838.
35. + of fission yeast encodes a protein kinase potentially regulated by phosphorylation. Cell, 45, 261-268.
36. cdc2. EMBO J., 13, 584-594.
37. Stone,E.M., Yamano,H., Kinoshita,N. and Yanagida,M. (1993) Mitotic regulation of protein phosphatases by the fission yeast sds22 protein. Curr. Biol., 3, 13-26.
38. Sudakin,V., Ganoth,D., Dahan,A., Heller,H., Hershhko,J., Luca,F., Ruderman,J.V. and Hershko,A. (1995) The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis. Mol. Biol. Cell, 6, 185-198.
39. Surana,U., Amon,A., Dowzer,C., McGrew,J., Byers,B. and Nasmyth,K. (1993) Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast. EMBO J., 12, 1969-1978.
40. Tugendreich,S., Tomkiel,J., Earnshaw,W. and Hieter,P. (1995) The CDC27HS protein co-localizes with the CDC16HS protein to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition. Cell, 81, 261-268.
41. + gene regulates spindle pole body duplication and has homology to the budding yeast ESP1 gene. Cell, 62, 913-925.
42. cdc2. Mol. Biol. Cell., 5, 713-724.
43. Woods,A., Sherwin,T., Sasse,R., McRae,T.H., Baines,A.J. and Gull,K. (1989) Definition of individual components within the cytoskeleton of Trypanosoma brucei by a library of monoclonal antibodies. J. Cell Sci.,93, 491-500.
44. Yamada,H., Kumada,K. and Yanagida,M. (1997) Distinct subunit functions and cell cycle regulated phosphorylation of 20S APC/cyclosome required for anaphase in fission yeast. J. Cell Sci., 110, 1793-1804.
45. Yamano,H., Gannon,J. and Hunt,T. (1996) The role of proteolysis in cell cycle progression in Schizosaccharomyces pombe. EMBO J., 15, 5268-5279.
46. Yamashita,M.Y., Nakaseko,Y., Samejima,I., Kumada,K., Yamada,H., Michaelson,D. and Yanagida,M. (1996) 20S cyclosome complex formation and proteolytic activity inhibited by the cAMP/PKA pathway. Nature, 384, 276-279.
47. Yu,H., King,R.W., Peters,J.M. and Kirschner,M.W. (1996) Identification of a novel ubiquitin-conjugating enzyme involved in mitotic cyclin degradation. Curr. Biol., 6, 455-465.
48. Zachariae,W., Shin,T.H., Galova,M., Obermaier,B. and Nasmyth,K. (1996) Identification of subunits of the anaphase-promoting complex of Saccharomyces cerevisiae. Science, 274, 1201-1204.