메뉴 건너뛰기




Volumn 26, Issue 9-10, 2000, Pages 771-780

Regulation of primary carbon metabolism in Kluyveromyces lactis

Author keywords

Crabtree effect; Fermentation; Glucose repression; Glucose transport; Rag mutants; Respiration; Yeast

Indexed keywords

BIOCHEMISTRY; CARBON; ENZYMES; FERMENTATION; GLUCOSE; METABOLISM; MOLECULAR DYNAMICS; PHYSIOLOGY; RESPIRATORY MECHANICS;

EID: 0034212457     PISSN: 01410229     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0141-0229(00)00170-8     Document Type: Conference Paper
Times cited : (93)

References (79)
  • 1
    • 0013936130 scopus 로고
    • The crabtree effect: A regulatory system in yeast
    • De Deken R.H. The crabtree effect a regulatory system in yeast . J Gen Microbiol. 44:1966;149-156.
    • (1966) J Gen Microbiol , vol.44 , pp. 149-156
    • De Deken, R.H.1
  • 2
    • 0343550889 scopus 로고
    • Über die Wirkung von Blausäureäthylester (Äthylcarbylamin)
    • Warburg O. Über die Wirkung von Blausäureäthylester (Äthylcarbylamin). Biochem Zeitschrift. 172:1926;432-441.
    • (1926) Biochem Zeitschrift , vol.172 , pp. 432-441
    • Warburg, O.1
  • 3
    • 0026334731 scopus 로고
    • Physiology of yeasts in relation to biomass yields
    • Verduyn C. Physiology of yeasts in relation to biomass yields. Antonie Van Leeuwenhoek. 60:1991;325-353.
    • (1991) Antonie Van Leeuwenhoek , vol.60 , pp. 325-353
    • Verduyn, C.1
  • 4
    • 0024635244 scopus 로고
    • RAG1 and RAG2: Nuclear genes involved in the dependence/independence on mitochondrial respiratory function for growth on sugars
    • Goffrini P., Algeri A.A., Donnini C., Wésolowski-Louvel M., Ferrero I. RAG1 and RAG2 nuclear genes involved in the dependence/independence on mitochondrial respiratory function for growth on sugars . Yeast. 5:1989;99-106.
    • (1989) Yeast , vol.5 , pp. 99-106
    • Goffrini, P.1    Algeri, A.A.2    Donnini, C.3    Wésolowski-Louvel, M.4    Ferrero, I.5
  • 5
    • 0026630077 scopus 로고
    • - mutations involved in glucose metabolism in yeast: Isolation and genetic characterization
    • - mutations involved in glucose metabolism in yeast isolation and genetic characterization . Yeast. 8:1992;711-719.
    • (1992) Yeast , vol.8 , pp. 711-719
    • Wésolowski-Louvel, M.1    Prior, C.2    Bornecque, D.3    Fukuhara, H.4
  • 6
    • 0028949280 scopus 로고
    • Identification of novel HXT genes in Saccharomyces cerevisiae reveals the impact of individual hexose transporters on glycolytic flux
    • Reifenberger E., Freidel K., Ciriacy M. Identification of novel HXT genes in Saccharomyces cerevisiae reveals the impact of individual hexose transporters on glycolytic flux. Mol Microbiol. 16:1995;157-167.
    • (1995) Mol Microbiol , vol.16 , pp. 157-167
    • Reifenberger, E.1    Freidel, K.2    Ciriacy, M.3
  • 7
    • 0030953385 scopus 로고    scopus 로고
    • The molecular genetics of hexose transport in yeasts
    • Boles E., Hollenberg C.P. The molecular genetics of hexose transport in yeasts. FEMS Microbiol Rev. 21:1997;85-111.
    • (1997) FEMS Microbiol Rev , vol.21 , pp. 85-111
    • Boles, E.1    Hollenberg, C.P.2
  • 8
    • 0033373342 scopus 로고    scopus 로고
    • Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae
    • Wieczorke R., Krampe S., Weierstall T., Freidel K., Hollenberg C.P., Boles E. Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. FEBS Lett. 464:1999;123-128.
    • (1999) FEBS Lett , vol.464 , pp. 123-128
    • Wieczorke, R.1    Krampe, S.2    Weierstall, T.3    Freidel, K.4    Hollenberg, C.P.5    Boles, E.6
  • 9
    • 0026780836 scopus 로고
    • Glucose transport in the yeast Kluyveromyces lactis. I. Properties of an inducible low-affinity glucose transporter gene
    • Wésolowski-Louvel M., Goffrini P., Ferrero I. Glucose transport in the yeast Kluyveromyces lactis. I. Properties of an inducible low-affinity glucose transporter gene. Mol Gen Genet. 233:1992;89-96.
    • (1992) Mol Gen Genet , vol.233 , pp. 89-96
    • Wésolowski-Louvel, M.1    Goffrini, P.2    Ferrero, I.3
  • 10
    • 0030797933 scopus 로고    scopus 로고
    • Influence of mutations in hexose-transporter genes on glucose repression in Kluyveromyces lactis
    • Weirich J., Goffrini P., Kuger P., Ferrero I., Breunig K.D. Influence of mutations in hexose-transporter genes on glucose repression in Kluyveromyces lactis. Eur J Biochem. 249:1997;248-257.
    • (1997) Eur J Biochem , vol.249 , pp. 248-257
    • Weirich, J.1    Goffrini, P.2    Kuger, P.3    Ferrero, I.4    Breunig, K.D.5
  • 12
    • 0026719343 scopus 로고
    • Glucose transport in the yeast Kluyveromyces lactis. II. Transcriptional regulation of the glucose transporter gene RAG1
    • Chen X.J., Wésolowski-Louvel M., Fukuhara H. Glucose transport in the yeast Kluyveromyces lactis. II. Transcriptional regulation of the glucose transporter gene RAG1. Mol Gen Genet. 233:1992;97-105.
    • (1992) Mol Gen Genet , vol.233 , pp. 97-105
    • Chen, X.J.1    Wésolowski-Louvel, M.2    Fukuhara, H.3
  • 13
    • 0029811217 scopus 로고    scopus 로고
    • A novel signal transduction pathway in Saccharomyces cerevisiae defined by Snf3-regulated expression of HXT6
    • Liang H., Gaber R.F. A novel signal transduction pathway in Saccharomyces cerevisiae defined by Snf3-regulated expression of HXT6. Mol Biol Cell. 7:1996;1953-1966.
    • (1996) Mol Biol Cell , vol.7 , pp. 1953-1966
    • Liang, H.1    Gaber, R.F.2
  • 14
    • 0029864499 scopus 로고    scopus 로고
    • Two glucose transporters in Saccharomyces cerevisiae are glucose sensors that generate a signal for induction of gene expression
    • Özcan S, Dover J, Rosenwald AG, Wölfl S, Johnston M. Two glucose transporters in Saccharomyces cerevisiae are glucose sensors that generate a signal for induction of gene expression. Proc Natl Acad Sci USA 1996,93:12428-32.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 12428-12432
    • Özcan, S.1    Dover, J.2    Rosenwald, A.G.3    Wölfl, S.4    Johnston, M.5
  • 15
    • 0032080298 scopus 로고    scopus 로고
    • Glucose sensing and signaling by two glucose receptors in the yeast Saccharomyces cerevisiae
    • Özcan S., Dover J., Johnston M. Glucose sensing and signaling by two glucose receptors in the yeast Saccharomyces cerevisiae. EMBO J. 17:1998;2566-2573.
    • (1998) EMBO J , vol.17 , pp. 2566-2573
    • Özcan, S.1    Dover, J.2    Johnston, M.3
  • 16
    • 0031026141 scopus 로고    scopus 로고
    • The Kluyveromyces lactis equivalent of casein kinase I is required for the transcription of the gene encoding the low-affinity glucose permease
    • Blaisonneau J., Fukuhara H., Wésolowski-Louvel M. The Kluyveromyces lactis equivalent of casein kinase I is required for the transcription of the gene encoding the low-affinity glucose permease. Mol Gen Genet. 253:1997;469-477.
    • (1997) Mol Gen Genet , vol.253 , pp. 469-477
    • Blaisonneau, J.1    Fukuhara, H.2    Wésolowski-Louvel, M.3
  • 17
    • 0028948313 scopus 로고
    • The GCR1 requirement for yeast glycolytic gene expression is suppressed by dominant mutations in the SGC1 gene, which encodes a novel basic-helix-loop-helix protein
    • Nishi K., Park C.S., Pepper A.E., Eichinger G., Innis M.A., Holland M.J. The GCR1 requirement for yeast glycolytic gene expression is suppressed by dominant mutations in the SGC1 gene, which encodes a novel basic-helix-loop-helix protein. Mol Cell Biol. 15:1995;2646-2653.
    • (1995) Mol Cell Biol , vol.15 , pp. 2646-2653
    • Nishi, K.1    Park, C.S.2    Pepper, A.E.3    Eichinger, G.4    Innis, M.A.5    Holland, M.J.6
  • 18
    • 0027280268 scopus 로고
    • The hexokinase gene is required for transcriptional regulation of the glucose transporter gene RAG1 in Kluyveromyces lactis
    • Prior C., Mamessier P., Fukuhara H., Chen X.J., Wésolowski-Louvel M. The hexokinase gene is required for transcriptional regulation of the glucose transporter gene RAG1 in Kluyveromyces lactis. Mol Cell Biol. 13:1993;3882-3889.
    • (1993) Mol Cell Biol , vol.13 , pp. 3882-3889
    • Prior, C.1    Mamessier, P.2    Fukuhara, H.3    Chen, X.J.4    Wésolowski-Louvel, M.5
  • 19
    • 0024654217 scopus 로고
    • Glucose repression of LAC gene expression in yeast is mediated by the transcriptional activator LAC9
    • Breunig K.D. Glucose repression of LAC gene expression in yeast is mediated by the transcriptional activator LAC9. Mol Gen Genet. 216:1989;422-427.
    • (1989) Mol Gen Genet , vol.216 , pp. 422-427
    • Breunig, K.D.1
  • 21
    • 0027295271 scopus 로고
    • Glucose repression of lactose/galactose metabolism in Kluyveromyces lactis is determined by the concentration of the transcriptional activator LAC9 (KlGAL4)
    • Zachariae W., Kuger P., Breunig K.D. Glucose repression of lactose/galactose metabolism in Kluyveromyces lactis is determined by the concentration of the transcriptional activator LAC9 (KlGAL4). Nucleic Acids Res. 21:1993;69-77.
    • (1993) Nucleic Acids Res , vol.21 , pp. 69-77
    • Zachariae, W.1    Kuger, P.2    Breunig, K.D.3
  • 22
    • 0345131734 scopus 로고    scopus 로고
    • Heterologous protein secretion directed by a repressible acid phosphatase system of Kluyveromyces lactis: Characterization of upstream region-activating sequences in the KIPHO5 gene
    • Ferminan E., Dominguez A. Heterologous protein secretion directed by a repressible acid phosphatase system of Kluyveromyces lactis characterization of upstream region-activating sequences in the KIPHO5 gene . Appl Environ Microbiol. 64:1998;2403-2408.
    • (1998) Appl Environ Microbiol , vol.64 , pp. 2403-2408
    • Ferminan, E.1    Dominguez, A.2
  • 23
    • 0029942696 scopus 로고    scopus 로고
    • FOG1 and FOG2 genes, required for the transcriptional activation of glucose-repressible genes of Kluyveromyces lactis are homologous to GAL83 and SNF1 of Saccharomyces cerevisiae
    • Goffrini P., Ficarelli A., Donnini C., Lodi T., Puglisi P.P., Ferrero I. FOG1 and FOG2 genes, required for the transcriptional activation of glucose-repressible genes of Kluyveromyces lactis are homologous to GAL83 and SNF1 of Saccharomyces cerevisiae. Curr Genet. 29:1996;316-326.
    • (1996) Curr Genet , vol.29 , pp. 316-326
    • Goffrini, P.1    Ficarelli, A.2    Donnini, C.3    Lodi, T.4    Puglisi, P.P.5    Ferrero, I.6
  • 24
    • 0030293885 scopus 로고    scopus 로고
    • Glucose repression/derepression in budding yeast: SNF1 protein kinase is activated by phosphorylation under derepressing conditions, and this correlates with a high AMP:ATP ratio
    • Wilson W.A., Hawley S.A., Hardie D.G. Glucose repression/derepression in budding yeast SNF1 protein kinase is activated by phosphorylation under derepressing conditions, and this correlates with a high AMP:ATP ratio . Curr Biol. 6:1996;1426-1434.
    • (1996) Curr Biol , vol.6 , pp. 1426-1434
    • Wilson, W.A.1    Hawley, S.A.2    Hardie, D.G.3
  • 25
    • 0030953974 scopus 로고    scopus 로고
    • The Snf1 protein kinase and its activating subunit, Snf4, interact with distinct domains of the Sip1/Sip2/Gal83 component in the kinase complex
    • Jiang R., Carlson M. The Snf1 protein kinase and its activating subunit, Snf4, interact with distinct domains of the Sip1/Sip2/Gal83 component in the kinase complex. Mol Cell Biol. 17:1997;2099-2106.
    • (1997) Mol Cell Biol , vol.17 , pp. 2099-2106
    • Jiang, R.1    Carlson, M.2
  • 26
    • 0030468365 scopus 로고    scopus 로고
    • Glucose regulates protein interactions within the yeast SNF1 protein kinase complex
    • Jiang R., Carlson M. Glucose regulates protein interactions within the yeast SNF1 protein kinase complex. Genes Dev. 10:1996;3105-3115.
    • (1996) Genes Dev , vol.10 , pp. 3105-3115
    • Jiang, R.1    Carlson, M.2
  • 27
    • 0027504233 scopus 로고
    • Genetic and molecular characterization of GAL83: Its interaction and similarities with other genes involved in glucose repression in Saccharomyces cerevisiae
    • Erickson JR, Johnston M. Genetic and molecular characterization of GAL83: its interaction and similarities with other genes involved in glucose repression in Saccharomyces cerevisiae. Genetics 1993,135:655-64.
    • (1993) Genetics , vol.135 , pp. 655-664
    • Erickson, J.R.1    Johnston, M.2
  • 28
    • 0028559507 scopus 로고
    • A family of proteins containing a conserved domain that mediates interaction with the yeast SNF1 protein kinase complex
    • Yang X., Jiang R., Carlson M. A family of proteins containing a conserved domain that mediates interaction with the yeast SNF1 protein kinase complex. EMBO J. 13:1994;5878-5886.
    • (1994) EMBO J , vol.13 , pp. 5878-5886
    • Yang, X.1    Jiang, R.2    Carlson, M.3
  • 29
    • 0025004155 scopus 로고
    • Yeast MIG1 repressor is related to the mammalian early growth response and Wilms' tumour finger proteins
    • Nehlin J.O., Ronne H. Yeast MIG1 repressor is related to the mammalian early growth response and Wilms' tumour finger proteins. EMBO J. 9:1990;2891-2898.
    • (1990) EMBO J , vol.9 , pp. 2891-2898
    • Nehlin, J.O.1    Ronne, H.2
  • 31
    • 0033523996 scopus 로고    scopus 로고
    • The nuclear exportin Msn5 is required for nuclear export of the Mig1 glucose repressor of Saccharomyces cerevisiae
    • DeVit M.J., Johnston M. The nuclear exportin Msn5 is required for nuclear export of the Mig1 glucose repressor of Saccharomyces cerevisiae. Curr Biol. 9:1999;1231-1241.
    • (1999) Curr Biol , vol.9 , pp. 1231-1241
    • Devit, M.J.1    Johnston, M.2
  • 32
    • 0028302020 scopus 로고
    • A carbon source-responsive promoter element necessary for activation of the isocitrate lyase gene ICL1 is common to genes of the gluconeogenic pathway in the yeast Saccharomyces cerevisiae
    • Schöler A., Schüller H. A carbon source-responsive promoter element necessary for activation of the isocitrate lyase gene ICL1 is common to genes of the gluconeogenic pathway in the yeast Saccharomyces cerevisiae. Mol Cell Biol. 14:1994;3613-3622.
    • (1994) Mol Cell Biol , vol.14 , pp. 3613-3622
    • Schöler, A.1    Schüller, H.2
  • 33
    • 0028930777 scopus 로고
    • CAT8, a new zinc cluster-encoding gene necessary for derepression of gluconeogenetic enzymes in the yeast Saccharomyces cerevisiae
    • Hedges D., Proft M., Entian K. CAT8, a new zinc cluster-encoding gene necessary for derepression of gluconeogenetic enzymes in the yeast Saccharomyces cerevisiae. Mol Cell Biol. 15:1995;1915-1922.
    • (1995) Mol Cell Biol , vol.15 , pp. 1915-1922
    • Hedges, D.1    Proft, M.2    Entian, K.3
  • 34
    • 0030987084 scopus 로고    scopus 로고
    • Glucose derepression of gluconeogenic enzymes in Saccharomyces cerevisiae correlates with phosphorylation of the gene activator Cat8p
    • Randez-Gil F., Bojunga N., Proft M., Entian K.D. Glucose derepression of gluconeogenic enzymes in Saccharomyces cerevisiae correlates with phosphorylation of the gene activator Cat8p. Mol Cell Biol. 17:1997;2502-2510.
    • (1997) Mol Cell Biol , vol.17 , pp. 2502-2510
    • Randez-Gil, F.1    Bojunga, N.2    Proft, M.3    Entian, K.D.4
  • 35
    • 0030015273 scopus 로고    scopus 로고
    • Dual influence of the yeast Cat1p (Snf1p) protein kinase on carbon source-dependent transcriptional activation of gluconeogenic genes by the regulatory gene CAT8
    • Rahner A., Scholer A., Martens E., Gollwitzer B., Schuller H.J. Dual influence of the yeast Cat1p (Snf1p) protein kinase on carbon source-dependent transcriptional activation of gluconeogenic genes by the regulatory gene CAT8. Nucleic Acids Res. 24:1996;2331-2337.
    • (1996) Nucleic Acids Res , vol.24 , pp. 2331-2337
    • Rahner, A.1    Scholer, A.2    Martens, E.3    Gollwitzer, B.4    Schuller, H.J.5
  • 36
    • 0029082210 scopus 로고
    • The MIG1 repressor from Kluyveromyces lactis: Cloning, sequencing and functional analysis in Saccharomyces cerevisiae
    • Cassart J.P., Georis I., Östling J., Ronne H., Vandenhaute J. The MIG1 repressor from Kluyveromyces lactis cloning, sequencing and functional analysis in Saccharomyces cerevisiae . FEBS Lett. 371:1995;191-194.
    • (1995) FEBS Lett , vol.371 , pp. 191-194
    • Cassart, J.P.1    Georis, I.2    Östling, J.3    Ronne, H.4    Vandenhaute, J.5
  • 37
    • 0030611091 scopus 로고    scopus 로고
    • Glucose represses the lactose-galactose regulon in Kluyveromyces lactis through a SNF1 and MIG1-dependent pathway that modulates galactokinase (GAL1) gene expression
    • Dong J., Dickson R.C. Glucose represses the lactose-galactose regulon in Kluyveromyces lactis through a SNF1 and MIG1-dependent pathway that modulates galactokinase (GAL1) gene expression. Nucleic Acids Res. 25:1998;3657-3664.
    • (1998) Nucleic Acids Res , vol.25 , pp. 3657-3664
    • Dong, J.1    Dickson, R.C.2
  • 38
    • 0033028545 scopus 로고    scopus 로고
    • Transcription of the Kluyveromyces lactis invertase gene INV1 is glucose-repressed independently from MIG1
    • Georis I., Cassart J.-P., Breunig K.D., Vandenhaute J. Transcription of the Kluyveromyces lactis invertase gene INV1 is glucose-repressed independently from MIG1. Mol Gen Genet. 261:1999;862-870.
    • (1999) Mol Gen Genet , vol.261 , pp. 862-870
    • Georis, I.1    Cassart, J.-P.2    Breunig, K.D.3    Vandenhaute, J.4
  • 39
    • 0032870144 scopus 로고    scopus 로고
    • Deregulation of gluconeogenic structural genes by variants of the transcriptional activator Cat8p of the yeast Saccharomyces cerevisiae
    • Rahner A., Hiesinger M., Schüller H.J. Deregulation of gluconeogenic structural genes by variants of the transcriptional activator Cat8p of the yeast Saccharomyces cerevisiae. Mol Microbiol. 34:1999;146-156.
    • (1999) Mol Microbiol , vol.34 , pp. 146-156
    • Rahner, A.1    Hiesinger, M.2    Schüller, H.J.3
  • 40
    • 0032403110 scopus 로고    scopus 로고
    • Sip4, a Snf1 kinase-dependent transcriptional activator, binds to the carbon source-responsive element of gluconeogenic genes
    • Vincent O., Carlson M. Sip4, a Snf1 kinase-dependent transcriptional activator, binds to the carbon source-responsive element of gluconeogenic genes. EMBO J. 17:1998;7002-7008.
    • (1998) EMBO J , vol.17 , pp. 7002-7008
    • Vincent, O.1    Carlson, M.2
  • 42
    • 0029125357 scopus 로고
    • Carbon catabolite regulation of transcription of nuclear genes coding for mitochondrial proteins in the yeast Kluyveromyces lactis
    • Mulder W., Scholten I.H.J.M., Grivell L.A. Carbon catabolite regulation of transcription of nuclear genes coding for mitochondrial proteins in the yeast Kluyveromyces lactis. Curr Genet. 28:1995;267-273.
    • (1995) Curr Genet , vol.28 , pp. 267-273
    • Mulder, W.1    Scholten, I.H.J.M.2    Grivell, L.A.3
  • 44
    • 0024713582 scopus 로고
    • Identification, and Characterization of HAP4. A third component of the CCAAT-Bound HAP2/HAP3 Heteromer
    • Forsburg S.L., Guarente L. Identification, and Characterization of HAP4. A third component of the CCAAT-Bound HAP2/HAP3 Heteromer. Genes Develop. 3:1989;1166-1178.
    • (1989) Genes Develop , vol.3 , pp. 1166-1178
    • Forsburg, S.L.1    Guarente, L.2
  • 45
    • 0030669030 scopus 로고    scopus 로고
    • Exploring the metabolic and genetic control of gene expression on a genomic scale
    • DeRisi J.L., Iyer V.R., Brown P.O. Exploring the metabolic and genetic control of gene expression on a genomic scale. Science. 278:1997;680-686.
    • (1997) Science , vol.278 , pp. 680-686
    • Derisi, J.L.1    Iyer, V.R.2    Brown, P.O.3
  • 46
    • 0028855765 scopus 로고
    • Regulation of cytochrome c expression in the aerobic respiratory yeast Kluyveromyces lactis
    • Freire-Picos M.A., Hollenberg C.P., Breunig K.D., Cerdan M.E. Regulation of cytochrome c expression in the aerobic respiratory yeast Kluyveromyces lactis. FEBS Lett. 360:1995;39-42.
    • (1995) FEBS Lett , vol.360 , pp. 39-42
    • Freire-Picos, M.A.1    Hollenberg, C.P.2    Breunig, K.D.3    Cerdan, M.E.4
  • 47
    • 0033032597 scopus 로고    scopus 로고
    • HAP4, the glucose-repressed regulated subunit of the HAP transcriptional complex involved in the fermentation-respiration shift, has a functional homologue in the respiratory yeast Kluyveromyces lactis
    • Bourgarel D., Nguyen C., Bolotin-Fukuhara M. HAP4, the glucose-repressed regulated subunit of the HAP transcriptional complex involved in the fermentation-respiration shift, has a functional homologue in the respiratory yeast Kluyveromyces lactis. Mol Microbiol. 31:1999;1205-1216.
    • (1999) Mol Microbiol , vol.31 , pp. 1205-1216
    • Bourgarel, D.1    Nguyen, C.2    Bolotin-Fukuhara, M.3
  • 48
    • 0028814923 scopus 로고
    • The respiratory system of Kluyveromyces lactis escapes from HAP2 control
    • Nguyen C., Bolotin-Fukuhara M., Wésolowski-Louvel M., Fukuhara H. The respiratory system of Kluyveromyces lactis escapes from HAP2 control. Gene. 152:1995;113-115.
    • (1995) Gene , vol.152 , pp. 113-115
    • Nguyen, C.1    Bolotin-Fukuhara, M.2    Wésolowski-Louvel, M.3    Fukuhara, H.4
  • 49
    • 0027984349 scopus 로고
    • Sequence of the HAP3 transcription factor of Kluyveromyces lactis predicts the presence of a novel 4-cysteine zinc-finger motif
    • Mulder W., Scholten I.H.J.M., De Boer R.W., Grivell L.A. Sequence of the HAP3 transcription factor of Kluyveromyces lactis predicts the presence of a novel 4-cysteine zinc-finger motif. Mol Gen Genet. 245:1994;96-106.
    • (1994) Mol Gen Genet , vol.245 , pp. 96-106
    • Mulder, W.1    Scholten, I.H.J.M.2    De Boer, R.W.3    Grivell, L.A.4
  • 50
    • 0031872068 scopus 로고    scopus 로고
    • Transcriptional regulation of the KlDLD gene, encoding the mitochondrial enzyme D-lactate ferricytochrome c oxidoreductase in Kluyveromyces lactis: Effect of Klhap2 and fog mutations
    • Lodi T., Goffrini P., Bolondi I., Ferrero I. Transcriptional regulation of the KlDLD gene, encoding the mitochondrial enzyme D-lactate ferricytochrome c oxidoreductase in Kluyveromyces lactis effect of Klhap2 and fog mutations . Curr Genet. 34:1998;12-20.
    • (1998) Curr Genet , vol.34 , pp. 12-20
    • Lodi, T.1    Goffrini, P.2    Bolondi, I.3    Ferrero, I.4
  • 51
    • 0032423257 scopus 로고    scopus 로고
    • Inactivation of the Kluyveromyces lactis KlPDA1 gene leads to loss of pyruvate dehydrogenase activity, impairs growth on glucose and triggers aerobic alcoholic fermentation
    • Zeeman A.M., Luttik M.A., Thiele C., Van Dijken J.P., Pronk J.T., Steensma H.Y. Inactivation of the Kluyveromyces lactis KlPDA1 gene leads to loss of pyruvate dehydrogenase activity, impairs growth on glucose and triggers aerobic alcoholic fermentation. Microbiology. 144:1998;3437-3446.
    • (1998) Microbiology , vol.144 , pp. 3437-3446
    • Zeeman, A.M.1    Luttik, M.A.2    Thiele, C.3    Van Dijken, J.P.4    Pronk, J.T.5    Steensma, H.Y.6
  • 52
    • 0022989417 scopus 로고
    • Regulation of carbon metabolism in Saccharomyces cerevisiae and related yeasts
    • Käppeli O. Regulation of carbon metabolism in Saccharomyces cerevisiae and related yeasts. Adv Microb Physiol. 28:1986;181-209.
    • (1986) Adv Microb Physiol , vol.28 , pp. 181-209
    • Käppeli, O.1
  • 53
    • 0025784870 scopus 로고    scopus 로고
    • Dynamics of yeast metabolism and regulation
    • Sonnleitner B. Dynamics of yeast metabolism and regulation. Bioprocess Eng. 6:1999;187-193.
    • (1999) Bioprocess Eng , vol.6 , pp. 187-193
    • Sonnleitner, B.1
  • 54
    • 0030049641 scopus 로고    scopus 로고
    • The 'petite-negative' yeast Kluyveromyces lactis has a single gene expressing pyruvate decarboxylase activity
    • Bianchi M.M., Tizzani L., Destruelle M., Frontali L., Wésolowski-Louvel M. The 'petite-negative' yeast Kluyveromyces lactis has a single gene expressing pyruvate decarboxylase activity. Mol Microbiol. 19:1996;27-36.
    • (1996) Mol Microbiol , vol.19 , pp. 27-36
    • Bianchi, M.M.1    Tizzani, L.2    Destruelle, M.3    Frontali, L.4    Wésolowski-Louvel, M.5
  • 55
    • 0032579854 scopus 로고    scopus 로고
    • Regulation of alcoholic fermentation in batch and chemostat cultures of Kluyveromyces lactis CBS 2359
    • Kiers J., Zeeman A.-M., Luttik M., et al. Regulation of alcoholic fermentation in batch and chemostat cultures of Kluyveromyces lactis CBS 2359. Yeast. 14:1998;459-469.
    • (1998) Yeast , vol.14 , pp. 459-469
    • Kiers, J.1    Zeeman, A.-M.2    Luttik, M.3
  • 56
    • 0033616922 scopus 로고    scopus 로고
    • Regulation of the expression of the Kluyveromyces lactis PDC1 gene: Carbon source responsive elements and autoregulation
    • Destruelle M., Menghini R., Frontali L., Bianchi M.M. Regulation of the expression of the Kluyveromyces lactis PDC1 gene Carbon source responsive elements and autoregulation . Yeast. 15:1999;361-370.
    • (1999) Yeast , vol.15 , pp. 361-370
    • Destruelle, M.1    Menghini, R.2    Frontali, L.3    Bianchi, M.M.4
  • 57
    • 0030015216 scopus 로고    scopus 로고
    • RAG3 gene and transcriptional regulation of the pyruvate decarboxylase gene of Kluyveromyces lactis
    • Prior C., Tizzani L., Fukuhara H., Wésolowski-Louvel M. RAG3 gene and transcriptional regulation of the pyruvate decarboxylase gene of Kluyveromyces lactis. Mol Microbiol. 20:1996;765-772.
    • (1996) Mol Microbiol , vol.20 , pp. 765-772
    • Prior, C.1    Tizzani, L.2    Fukuhara, H.3    Wésolowski-Louvel, M.4
  • 58
    • 0027330910 scopus 로고
    • Characterisation of PDC2, a gene necessary for high level expression of pyruvate decarboxylase structural genes in Saccharomyces cerevisiae
    • Hohmann S. Characterisation of PDC2, a gene necessary for high level expression of pyruvate decarboxylase structural genes in Saccharomyces cerevisiae. Mol Gen Genet. 241:1993;657-666.
    • (1993) Mol Gen Genet , vol.241 , pp. 657-666
    • Hohmann, S.1
  • 59
    • 21844523866 scopus 로고
    • PDC2, a yeast gene essential for synthesis of pyruvate decarboxylase, encodes a novel transcription factor
    • Raghuram V., Lobo Z., Maitra P.K. PDC2, a yeast gene essential for synthesis of pyruvate decarboxylase, encodes a novel transcription factor. J Genet. 73:1994;17-32.
    • (1994) J Genet , vol.73 , pp. 17-32
    • Raghuram, V.1    Lobo, Z.2    Maitra, P.K.3
  • 60
    • 0032211885 scopus 로고    scopus 로고
    • The RAG3 gene of Kluyveromyces lactis is involved in the transcriptional regulation of genes implicated in pyruvate utilization and genes of the biosynthesis of thiamine pyrophosphate
    • Tizzani L., Meacock P., Frontali L., Wésolowski-Louvel M. The RAG3 gene of Kluyveromyces lactis is involved in the transcriptional regulation of genes implicated in pyruvate utilization and genes of the biosynthesis of thiamine pyrophosphate. FEMS Microbiol Lett. 168:1998;25-30.
    • (1998) FEMS Microbiol Lett , vol.168 , pp. 25-30
    • Tizzani, L.1    Meacock, P.2    Frontali, L.3    Wésolowski-Louvel, M.4
  • 61
    • 0029584856 scopus 로고
    • Two mitochondrial alcohol dehydrogenase activities of Kluyveromyces lactis are differently expressed during respiration and fermentation
    • Saliola M., Falcone C. Two mitochondrial alcohol dehydrogenase activities of Kluyveromyces lactis are differently expressed during respiration and fermentation. Mol Gen Genet. 249:1995;665-672.
    • (1995) Mol Gen Genet , vol.249 , pp. 665-672
    • Saliola, M.1    Falcone, C.2
  • 62
    • 0032906221 scopus 로고    scopus 로고
    • Use of the KlADH4 promoter for ethanol-dependent production of recombinant human serum albumin in Kluyveromyces lactis
    • Saliola M., Mazzoni C., Solimando N., et al. Use of the KlADH4 promoter for ethanol-dependent production of recombinant human serum albumin in Kluyveromyces lactis. Appl Environ Microbiol. 65:1999;53-60.
    • (1999) Appl Environ Microbiol , vol.65 , pp. 53-60
    • Saliola, M.1    Mazzoni, C.2    Solimando, N.3
  • 64
    • 0022372049 scopus 로고
    • Construction of strains of Saccharomyces cerevisiae that grow on lactose
    • Sreekrishna K., Dickson R.C. Construction of strains of Saccharomyces cerevisiae that grow on lactose. Proc Natl Acad Sci USA. 82:1985;7909-7913.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 7909-7913
    • Sreekrishna, K.1    Dickson, R.C.2
  • 65
    • 0019469337 scopus 로고
    • Transcriptional Regulation of the Kluyveromyces lactis β-Galactosidase Gene
    • Lacy L.R., Dickson R.C. Transcriptional Regulation of the Kluyveromyces lactis β-Galactosidase Gene. Mol Cell Biol. 1:1981;629-634.
    • (1981) Mol Cell Biol , vol.1 , pp. 629-634
    • Lacy, L.R.1    Dickson, R.C.2
  • 66
    • 0024297081 scopus 로고
    • The organization and transcription of the galactose gene cluster of Kluyveromyces lactis
    • Webster T.D., Dickson R.C. The organization and transcription of the galactose gene cluster of Kluyveromyces lactis. Nucleic Acids Res. 16:1988;8011-8028.
    • (1988) Nucleic Acids Res , vol.16 , pp. 8011-8028
    • Webster, T.D.1    Dickson, R.C.2
  • 67
    • 0023046315 scopus 로고
    • Analysis of the Kluyveromyces lactis positive regulatory gene LAC9 reveals functional homology to, but sequence divergence from, the Saccharomyces cerevisiae GAL4 gene
    • Salmeron J.M., Johnston S.A. Analysis of the Kluyveromyces lactis positive regulatory gene LAC9 reveals functional homology to, but sequence divergence from, the Saccharomyces cerevisiae GAL4 gene. Nucleic Acids Res. 14:1986;7767-7781.
    • (1986) Nucleic Acids Res , vol.14 , pp. 7767-7781
    • Salmeron, J.M.1    Johnston, S.A.2
  • 68
    • 0020505047 scopus 로고
    • Characterization of lactose transport in Kluyveromyces lactis
    • Dickson R.C., Barr K. Characterization of lactose transport in Kluyveromyces lactis. J Bacteriol. 154:1983;1245-1251.
    • (1983) J Bacteriol , vol.154 , pp. 1245-1251
    • Dickson, R.C.1    Barr, K.2
  • 69
    • 0031037914 scopus 로고    scopus 로고
    • Constitutive expression in gal7 mutants of Kluyveromyces lactis is due to internal production of galactose as an inducer of the Gal/Lac regulon
    • Cardinali G., Vollenbroich V., Jeon M.S., de Graaf A.A., Hollenberg C.P. Constitutive expression in gal7 mutants of Kluyveromyces lactis is due to internal production of galactose as an inducer of the Gal/Lac regulon. Mol Cell Biol. 17:1997;1722-1730.
    • (1997) Mol Cell Biol , vol.17 , pp. 1722-1730
    • Cardinali, G.1    Vollenbroich, V.2    Jeon, M.S.3    De Graaf, A.A.4    Hollenberg, C.P.5
  • 70
    • 0027290523 scopus 로고
    • Autoregulation of GAL4 transcription is essential for rapid growth of Kluyveromyces lactis on lactose and galactose
    • Czyz M., Nagiec M.M., Dickson R.C. Autoregulation of GAL4 transcription is essential for rapid growth of Kluyveromyces lactis on lactose and galactose. Nucleic Acids Res. 21:1993;4378-4382.
    • (1993) Nucleic Acids Res , vol.21 , pp. 4378-4382
    • Czyz, M.1    Nagiec, M.M.2    Dickson, R.C.3
  • 71
    • 0027168365 scopus 로고
    • Expression of the transcriptional activator LAC9 (KlGAL4) in Kluyveromyces lactis is controlled by autoregulation
    • Zachariae W., Breunig K.D. Expression of the transcriptional activator LAC9 (KlGAL4) in Kluyveromyces lactis is controlled by autoregulation. Mol Cell Biol. 13:1993;3058-3066.
    • (1993) Mol Cell Biol , vol.13 , pp. 3058-3066
    • Zachariae, W.1    Breunig, K.D.2
  • 72
  • 73
    • 0025997532 scopus 로고
    • Galactokinase encoded by GAL1 is a bifunctional protein required for induction of the GAL genes in Kluyveromyces lactis and is able to suppress the gal3 phenotype in Saccharomyces cerevisiae
    • Meyer J., Walker-Jonah A., Hollenberg C.P. Galactokinase encoded by GAL1 is a bifunctional protein required for induction of the GAL genes in Kluyveromyces lactis and is able to suppress the gal3 phenotype in Saccharomyces cerevisiae. Mol Cell Biol. 11:1991;5454-5461.
    • (1991) Mol Cell Biol , vol.11 , pp. 5454-5461
    • Meyer, J.1    Walker-Jonah, A.2    Hollenberg, C.P.3
  • 74
    • 0032527810 scopus 로고    scopus 로고
    • The yeast galactose genetic switch is mediated by the formation of a Gal4p-Gal80p-Gal3p complex
    • Platt A., Reece R.J. The yeast galactose genetic switch is mediated by the formation of a Gal4p-Gal80p-Gal3p complex. EMBO J. 17:1998;4086-4091.
    • (1998) EMBO J , vol.17 , pp. 4086-4091
    • Platt, A.1    Reece, R.J.2
  • 75
    • 0023353293 scopus 로고
    • Isolation and characterization of mutants of Kluyveromyces lactis defective in lactose transport
    • Sreekrishna K, Bhairi SM, Dickson RC. Isolation and characterization of mutants of Kluyveromyces lactis defective in lactose transport. Mol Gen Genet 1987;208:145-51.
    • (1987) Mol Gen Genet , vol.208 , pp. 145-151
    • Sreekrishna, K.1    Bhairi, S.M.2    Dickson, R.C.3
  • 76
    • 0024289194 scopus 로고
    • Primary structure of the lactose permease gene from the yeast Kluyveromyces lactis
    • Chang Y.-D., Dickson R.C. Primary structure of the lactose permease gene from the yeast Kluyveromyces lactis. J Biol Chem. 263:1988;16696-16703.
    • (1988) J Biol Chem , vol.263 , pp. 16696-16703
    • Chang, Y.-D.1    Dickson, R.C.2
  • 77
    • 0027515037 scopus 로고
    • Gal80 proteins of Kluyveromyces lactis and Saccharomyces cervisiae are highly conserved but contribute differently to glucose repression of the galactose regulon
    • Zenke F., Zachariae W., Lunkes A., Breunig K.D. Gal80 proteins of Kluyveromyces lactis and Saccharomyces cervisiae are highly conserved but contribute differently to glucose repression of the galactose regulon. Mol Cell Biol. 13:1993;7566-7576.
    • (1993) Mol Cell Biol , vol.13 , pp. 7566-7576
    • Zenke, F.1    Zachariae, W.2    Lunkes, A.3    Breunig, K.D.4
  • 78
    • 0026639462 scopus 로고
    • The signal for glucose repression of the lactose-galactose regulon is amplified through subtle modulation of transcription of the Kluyveromyces lactis Kl-GAL4 activator gene
    • Kuzhandaivelu N., Jones W.K., Martin A.K., Dickson R.C. The signal for glucose repression of the lactose-galactose regulon is amplified through subtle modulation of transcription of the Kluyveromyces lactis Kl-GAL4 activator gene. Mol Cell Biol. 12:1992;1924-1931.
    • (1992) Mol Cell Biol , vol.12 , pp. 1924-1931
    • Kuzhandaivelu, N.1    Jones, W.K.2    Martin, A.K.3    Dickson, R.C.4
  • 79
    • 0025821220 scopus 로고
    • A phosphoglucose isomerase gene is involved in the Rag phenotype of the yeast Kluyveromyces lactis
    • Goffrini P., Wésolowski-Louvel M., Ferrero I. A phosphoglucose isomerase gene is involved in the Rag phenotype of the yeast Kluyveromyces lactis. Mol Gen Genet. 228:1991;401-409.
    • (1991) Mol Gen Genet , vol.228 , pp. 401-409
    • Goffrini, P.1    Wésolowski-Louvel, M.2    Ferrero, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.