Glucose repression of the Kluyveromyces lactis invertase gene KIINV1 does not require Mig1p

Molecular and General Genetics

Volumn 261, Issue 4-5, 1999, Pages 862-870

  Georis, I ^a,b   Cassart, J P ^a   Breunig, K D ^b   Vandenhaute, Jean ^a  

^a UNIVERSITY OF NAMUR   (Belgium)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Glucose repression; INV1; Kluyveromyces lactis; MIG1

Indexed keywords

BETA FRUCTOFURANOSIDASE; GLUCOSE; INULINASE;

AMINO ACID SEQUENCE; ARTICLE; CLONING; FUNGAL GENETICS; GENE DISRUPTION; GENE ISOLATION; GENE REPRESSION; KLUYVEROMYCES; MOLECULAR CLONING; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SOUTHERN BLOTTING;

AMINO ACID SEQUENCE; BASE SEQUENCE; BETA-FRUCTOFURANOSIDASE; CLONING, MOLECULAR; DNA PRIMERS; DNA-BINDING PROTEINS; ENZYME REPRESSION; ESCHERICHIA COLI; GENES, FUNGAL; GLYCOSIDE HYDROLASES; KLUYVEROMYCES; MOLECULAR SEQUENCE DATA; PHYLOGENY; PLASMIDS; POLYMERASE CHAIN REACTION; RECOMBINANT PROTEINS; REPRESSOR PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ALIGNMENT; ZINC FINGERS;

EID: 0033028545     PISSN: 00268925     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004380050030     Document Type: Article

References (64)

1. Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, Miller W, Lipman DJ (1997) Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 25:3389-3402
2. Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K (1994) Current protocols in molecular biology. Wiley, New York
3. Barns SM, Lane DJ, Sogin ML, Bibeau C, Weisburg WG (1991) Evolutionary relationships among pathogenic Candida species and relatives. J Bacteriol 173:2250-2255
4. Berben G, Dumont J, Gilliquet V, Bolle PA, Hilger F (1991) The YDp plasmids: a uniform set of vectors bearing versatile gene disruption cassettes for Saccharomyces cerevisiae. Yeast 7:475-477
5. Bergkamp RJM, Geerse RH, Verbakel JMA, Planta RJ (1993) Cloning and sequencing of the URA3 gene of Kluyveromyces marxianus CBS 6556. Yeast 9:677-681
6. Bianchi MM, Tizzani L, Destruelle M, Frontali L, Wesolowski-Louvel M (1996) The 'petite-negative' yeast Kluyveromyces lactis has a single gene expressing pyruvate decarboxylase activity. Mol Microbiol 19:27-36
7. Bonneaud N, Ozier-Kalogeropoulos O, Li GY, Labouesse M, Minvielle-Sebastia L, Lacroute F (1991) A family of low and high copy replicative, integrative and single-stranded S. cerevisiae/E. coli shuttle vectors. Yeast 7:609-615
8. Breunig KD (1989) Glucose repression of LAC gene expression in yeast is mediated by the transcriptional activator LAC9. Mol Gen Genet 216:422-427
9. Breunig KD, Kuger P (1987) Functional homology between the yeast regulatory proteins GAL4 and LAC9: LAC9-mediated transcriptional activation in Kluyveromyces lactis involves protein binding to a regulatory sequence homologous to the GAL4 protein-binding site. Mol Cell Biol 7:4400-4406
10. Carlson M, Botstein D (1982) Two differentially regulated mRNAs with different 5′ ends encode secreted and intracellular forms of yeast invertase. Cell 28:145-154
11. Carlson M, Botstein D (1983) Organization of the SUC gene family in Saccharomyces. Mol Cell Biol 3:351-359
12. Carlson M, Celenza JL, Eng FJ (1985) Evolution of the dispersed SUC gene family of Saccharomyces by rearrangements of chromosomes telomeres. Mol Cell Biol 5:2894-2902
13. Cassart JP, Georis I, Östling J, Ronne H, Vandenhaute J (1995) The MIG1 repressor from Kluyveromyces lactis: cloning, sequencing and functional analysis in Saccharomyces cerevisiae. FEBS Lett 371:191-194
14. Cassart JP, Östling J, Ronne H, Vandenhaute J (1997) Comparative analysis in three fungi reveals structurally and functionally conserved regions in the Mig1 repressor. Mol Gen Genet 255:9-18
15. Chavez FP, Pons T, Delgado JM, Rodriguez L (1998) Cloning and sequence analysis of the gene encoding invertase (INV1) from the yeast Candida utilis. Yeast 14:1223-1232
16. De Deken RH (1966) The Crabtree effects and its relation to the petite mutation. J Gen Microbiol 44:157-165
17. Dong J, Dickson RC (1997) Glucose represses the lactose-galactose regulon in Kluyveromyces lactis through a SNF1 and MIG1-dependent pathway that modulates galactokinase (GAL1) gene expression. Nucleic Acids Res 25:3657-3664
18. Entian KD, Schüller HJ (1997a). Genetics of di- and trisaccharide utilization. In: Zimmermann FK, Entian KD (eds) Yeast sugar metabolism. Technomics, Lancaster, pp 225-233
19. Entian KD, Schüller HJ (1997b). Glucose repression (carbon catabolite repression) in yeast. In: Zimmermann FK, Entian KD (eds) Yeast sugar metabolism. Technomics, Lancaster, pp 409-434
20. Ferrero I, Rossi C, Landini MP, Puglisi PP (1978) Role of the mitochondrial protein synthesis is the catabolite repression of the petite-negative yeast K. lactis. Biochem Biophys Res Commun 80:340-348
21. Gancedo JM (1998) Yeast carbon catabolite repression. Microbiol Mol Biol Rev 62:334-361
22. Gietz RD, Schiestl RH, Willems AR, Woods RA (1995) Studies on the transformation of intact yeast cells by the LiAc/SS- DNA/ PEG procedure. Yeast 11:355-360
23. Goffrini P, Ficarelli A, Ferrero I (1995) Hexokinase activity is affected in mutants of Kluyveromyces lactis resistant to glucose repression. Microbiology 141:441-447
24. Goffrini P, Ficarelli A, Donnini C, Lodi T, Puglisi PP, Ferrero I (1996) FOG1 and FOG2 genes, required for the transcriptional activation of glucose-repressible genes of Kluyveromyces lactis, are homologous to GAL83 and SNF1 of Saccharomyces cerevisiae. Curr Genet 29:316-326
25. Goldstein A, Lampen JO (1975) β-D-fructofuranosidase from yeast. Methods Enzymol 76:504-511
26. Gozalbo D, Hohmann S (1989) The naturally occurring silent invertase structural gene suc2 zero contains an amber stop codon that is occasionally read through. Mol Gen Genet 216:511-516
27. Hedges D, Proft M, Entian KD (1995) CAT8, a new zinc cluster-encoding gene necessary for derepression of gluconeogenic enzymes in the yeast Saccharomyces cerevisiae. Mol Cell Biol 15:1915-1922
28. Hinnebusch AG, Liebman SW (1991) Protein synthesis and translational control in Saccharomyces cerevisiae. In: Broach JR, Pringle JR, Jones EW (eds) The Molecular and cellular biology of the yeast Saccharomyces. Genome dynamics, protein synthesis, and energetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y., pp 627-735
29. Janbon G, Rustchenko EP, Klug S, Scherer S, Sherman F (1997) Phylogenetic relationships of fungal cytochromes c. Yeast 13:985-990
30. Johnston M, Carlson M (1992) Regulation of carbon and phosphate utilisation. In: Broach JR, Pringle JR, Jones EW (eds) The Molecular and cellular biology of the yeast Saccharomyces. Gene expression. Cold Spring Harbor Laboratory Press, Cold Spring Hartbor, N.Y., pp 193-281
31. Johnston M, Flick JS, Pexton T (1994) Multiple mechanisms provide rapid and stringent glucose repression of GAL gene expression in Saccharomyces cerevisiae. Mol Cell Biol 14:3834-3841
32. Keleher CA, Redd MJ, Schultz J, Carlson M, Johnston AD (1992) Ssn6-Tup1 is a general repressor of transcription in yeast. Cell 68:709-719
33. Klein RD, Poorman RA, Favreau MA, Shea MH, Hatzenbuhler NT, Nulf SC (1989) Cloning and sequence analysis of the gene encoding invertase from the yeast Schanniomyces occidentalis. Curr Genet 16:145-152
34. Kuzhandaivelu N, Jones WK, Martin AK, Dickson RC (1992) The signal for glucose repression of the lactose-galactose regulon is amplified through subtle modulation of transcription of the Kluyveromyces lactis Kl-GAL4 activator gene. Mol Cell Biol 12:1924-1931
35. Ladrière JM, Delcour J, Vandenhaute J (1993) Sequence of a gene coding for a cytoplasmic alcohol dehydrogenase from Kluyveromyces marxianus ATCC 12424. Biochim Biophys Acta 1173:99-101
36. Laloux O, Cassart JP, Delcour J, Van Beeumen J, Vandenhaute J (1991) Cloning and sequencing of the inulinase gene of Kluyveromyces marxianus var. marxianus ATCC 12424. FEBS Lett 289:64-68
37. Lodi T, O'Connor D, Goffrini P, Ferrero I (1994) Carbon catabolite repression in Kluyveromyces lactis: isolation and characterization of the KlDLD gene encoding the mitochondrial enzyme D-lactate ferricytochrome c oxidoreductase. Mol Gen Genet 244:622-629
38. Luftiyya L, Johnston M (1996) Two zinc-finger-containing repressors are responsible for glucose repression of SUC2 expression. Mol Cell Biol 16:4790-4797
39. Lundin M, Nehlin JO, Ronne H (1994) Importance of a flanking AT-rich region in target site recognition by the GC box-binding zinc finger protein MIG1. Mol Cell Biol 14:1979-1985
40. Mortimer RK, Hawthorne DC (1969) Yeast genetics. In: Rose AH, Harrison JS (eds) The Yeasts. Academic Press, London, pp 385-460
41. Mulder W, Scholten IH, Grivell LA (1995) Carbon catabolite regulation of transcription of nuclear genes coding for mitochondrial proteins in the yeast Kluyveromyces lactis. Curr Genet 28:267-273
42. Nehlin JO, Ronne H (1990) Yeast MIG1 repressor is related to the mammalian early growth response and Wilms' tumour finger proteins. EMBO J 9:2891-2898
43. Östling J, Ronne H (1998) Negative control of the Mig1p repressor by Snf1p-dependent phosphorylation in the absence of glucose. Eur J Biochem 252:162-168
44. Pavletich NP, Pabo CO (1991) Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1Å. Science 252:809-817
45. Pérez JA, Rodriguez J, Rodriguez L, Ruiz T (1996) Cloning and sequence analysis of the invertase gene INV1 from the yeast Pichia anomala. Curr Genet 29:234-240
46. Perlman D, Halvorson HO (1981) Distinct repressible mRNAs for cytoplasmic and secreted yeast invertase are encoded by a single gene. Cell 25:525-536
47. Perlman D, Halvorson HO, Cannon LE (1982) Presecretory and cytoplasmic invertase polypeptides encoded by distinct mRNAs derived from the same structural gene differ by a signal sequence. Proc Natl Acad Sci USA 79:781-785
48. Prior C, Mamessier P, Fukuhara H, Chen XJ, Wésolowski-Louvel M (1993) The hexokinase gene is required for transcriptional regulation of the glucose transporter gene RAG1 in Kluyveromyces lactis. Mol Cell Biol 13:3882-3889
49. Reddy VA, Johnson RS, Biemann K, Williams RS, Ziegler FD, Trimble RB, Maley F (1988) Characterization of the glycosylation sites in yeast external invertase. I. N-linked oligosacharide content of the individual sequons. J Biol Chem 263:6978-6985
50. Reese MG, Eeckman FH (1995) Novel neural network algorithms for improved eukaryotic promoter site recognition. Proceedings Seventh International Genome Sequencing and Analysis Conference. Hilton Head Island, South Carolina
51. Ronne H (1995) Glucose repression in fungi. Trends Genet 11:12-17
52. Rothstein RJ (1983) One-step gene disruption in yeast. Methods Enzymol 101:202-211
53. Rouwenhorst RJ, Hensing M, Verbakel J, Scheffers WA, Van Dijken JP (1990a) Structure and properties of the extracellular inulinase of Kluyveromyces marxianus CBS 6556. Appl Env Microbiol 56:3337-3345
54. Rouwenhorst RJ, Ritmeester WS, Scheffers WA, Van Dijken JP (1990b) Localization of inulinase and invertase in Kluyveromyces species. Appl Env Microbiol 56:3329-3336
55. Snyder HE, Phaff HJ (1960) Studies on a Beta-fructosidase (inulinase) produced by Saccharomyces fragilis. J Microbiol Serol 26:433-452
56. Tanaka N, Ohuchi N, Mukai Y, Osaka Y, Ohtani Y, Tabuchi M, Bhuiyan MS, Fukui H, Harashima S, Takegawa K (1998) Isolation and characterization of an invertase and its repressor genes from Schizosaccharomyces pombe. Biochem Biophys Res Commun 245:246-253
57. Treitel MA, Carlson M (1995) Repression by SSN6-TUP1 is directed by MIG1, repressor/activator protein. Proc Natl Acad Sci USA 92:3132-3136
58. Treitel MA, Kuchin S, Carlson M (1998) Snf1 protein kinase regulates phosphorylation of the Mig1 repressor in Saccharomyces cerevisiae. Mol Cell Biol 18:6273-6280
59. Weirich J, Goffrini P, Kuger P, Ferrero I, Breunig KD (1997) Influence of mutations in hexose-transporter genes on glucose repression in Kluyveromyces lactis. Eur J Biochem 249:248-257
60. Wésolowski-Louvel M, Tanguy-Rougeau C, Fukuhara H (1988) A nuclear gene required for the expression of the linear DNA-associated killer system in the yeast Kluyveromyces lactis. Yeast 4:71-81
61. Wésolowski-Louvel M, Goffrini P, Ferrero I, Fukuhara H (1992) Glucose transport in the yeast Kluyveromyces lactis. I. Properties of an inducible low-affinity glucose transporter gene. Mol Gen Genet 233:89-96
62. Wésolowski-Louvel M, Breunig KD, Fukuhara H (1996) Kluyveromyces lactis. In: Wolf K (ed) Non-conventional yeasts in biotechnology. Springer, Berlin Heidelberg New York, pp 139-201
63. Zachariae W, Kuger P, Breunig KD (1993) Glucose repression of lactose/galactose metabolism in Kluyveromyces lactis is determined by the concentration of the transcriptional activator LAC9 (K1GAL4). Nucleic Acids Res 21:69-77
64. Zenke FT, Zachariae W, Lunkes A, Breunig KD (1993) Ga180 proteins of Kluyveromyces lactis and Saccharomyces cerevisiae are highly conserved by contribute differently to glucose repression of the galactose regulon. Mol Cell Biol 13:7566-7576