Synthesis and evaluation of 6-[18F]fluoro-3-(2(S)-azetidinylmethoxy)pyridine as a PET tracer for nicotinic acetylcholine receptors

Journal of Inorganic Biochemistry

Volumn 78, Issue 3, 2000, Pages 381-389

  Ding, Y S ^a   Liu, N ^a   Wang, T ^a   Marecek, J ^a   Garza, V ^a   Ojima, I ^a   Fowler, J S ^a  

^a BROOKHAVEN NATIONAL LABORATORY   (United States)

Author keywords

A 85380; ABT 594; F 18; Nicotinic acetylcholine receptors; Nucleophilic aromatic substitution; Positron emission tomography; Trimethylammonium

Indexed keywords

2 FLUORO 3 (2 AZETIDINYLMETHOXY)PYRIDINE F 18; 3 (2 AZETIDINYLMETHOXY)PYRIDINE; 5 (2 AZETIDINYLMETHOXY) 2 CHLOROPYRIDINE; 6 FLUORO 3 (2 AZETIDINYLMETHOXY)PYRIDINE F 18; EPIBATIDINE; FLUORINE 18; NICOTINIC AGENT; NICOTINIC RECEPTOR; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG; 5-(2-AZETIDINYLMETHOXY)-2-CHLOROPYRIDINE; AZETIDINE DERIVATIVE; DIAGNOSTIC AGENT; FLUORINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BABOON; BINDING AFFINITY; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; ISOTOPE LABELING; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; STRUCTURE ACTIVITY RELATION; ANIMAL; COMPUTER ASSISTED EMISSION TOMOGRAPHY; METABOLISM; PAPIO;

ANIMALIA; PAPIO HAMADRYAS;

ANIMALS; AZETIDINES; FEMALE; FLUORINE RADIOISOTOPES; ISOTOPE LABELING; PAPIO; PYRIDINES; RECEPTORS, NICOTINIC; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0034182449     PISSN: 01620134     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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