-
1
-
-
0029847368
-
Functional diversity of helper T lymphocytes
-
1 Abbas AK, Murphy KM, Sher A. Functional diversity of helper T lymphocytes. Nature 1996; 383:787-793.
-
(1996)
Nature
, vol.383
, pp. 787-793
-
-
Abbas, A.K.1
Murphy, K.M.2
Sher, A.3
-
2
-
-
0023232366
-
Two types of mouse helper T-cell clone. Implications for immune regulation
-
2 Mosmann TR, Coffmann RL. Two types of mouse helper T-cell clone. Implications for immune regulation. Immunol Today 1987; 8:223-227.
-
(1987)
Immunol Today
, vol.8
, pp. 223-227
-
-
Mosmann, T.R.1
Coffmann, R.L.2
-
3
-
-
0033371560
-
Susceptibility to infectious diseases: Leishmania as a paradigm
-
3 Locksley RM, Pingel S, Lacy D, Wakil AE, Bix M, Fowell DJ. Susceptibility to infectious diseases: Leishmania as a paradigm. J Infect Dis 1999; 179 (suppl 2):S305-S308.
-
(1999)
J Infect Dis
, vol.179
, Issue.SUPPL. 2
-
-
Locksley, R.M.1
Pingel, S.2
Lacy, D.3
Wakil, A.E.4
Bix, M.5
Fowell, D.J.6
-
4
-
-
0031755270
-
Genetic control of the T cell response to Leishmania major infection
-
Mechanisms of lymphocyte activation and immune regulation VII: molecular determinants of microbial immunity . Gupta S, Sher A, Ahmed R. New York: Plenum Press
-
4 Coffman RL, Beebe AM. Genetic control of the T cell response to Leishmania major infection. In: Mechanisms of lymphocyte activation and immune regulation VII: molecular determinants of microbial immunity. Gupta S, Sher A, Ahmed R (editors). Advances in Experimental Medicine and Biology; vol 452. New York: Plenum Press; 1998. pp. 61-66. A number of genetic loci conferring resistance to Leishmania infection have been identified using a novel method of serial backcrossing and selection for resistance.
-
(1998)
Advances in Experimental Medicine and Biology
, vol.452
, pp. 61-66
-
-
Coffman, R.L.1
Beebe, A.M.2
-
5
-
-
0032433126
-
Genetic regulation of commitment to interleukin 4 production by a CD4+ T cell-intrinsic mechanism
-
5 Bix M, Wang Z-E, Thiel B, Schork NJ, Locksley RM. Genetic regulation of commitment to interleukin 4 production by a CD4+ T cell-intrinsic mechanism. J Exp Med 1998; 188:2289-2293. A convincing article indicating that T cells from BALB/c mice have a higher propensity to produce IL-4 than cells from other mouse strains. This tendency has been linked to a locus on chromosome 16.
-
(1998)
J Exp Med
, vol.188
, pp. 2289-2293
-
-
Bix, M.1
Wang, Z.-E.2
Thiel, B.3
Schork, N.J.4
Locksley, R.M.5
-
6
-
-
0030923103
-
Resistance to Leishmania major is linked to the H2 region on Chromosome 17 and to Chromosome 9
-
6 Roberts LJ, Baldwin TM, Curtis JM, Handmann E, Foote SJ. Resistance to Leishmania major is linked to the H2 region on Chromosome 17 and to Chromosome 9. J Exp Med 1997; 185:1705-1711.
-
(1997)
J Exp Med
, vol.185
, pp. 1705-1711
-
-
Roberts, L.J.1
Baldwin, T.M.2
Curtis, J.M.3
Handmann, E.4
Foote, S.J.5
-
7
-
-
0029861329
-
Genetic maping of a murine locus controlling T helper 1/T helper 2 type responses
-
7 Gorham JD, Guler ML, Steen RG, Maokey AJ, Daly MJ, Frederick K, et al. Genetic maping of a murine locus controlling T helper 1/T helper 2 type responses. Proc Natl Acad Sci USA 1996; 93:12467.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 12467
-
-
Gorham, J.D.1
Guler, M.L.2
Steen, R.G.3
Maokey, A.J.4
Daly, M.J.5
Frederick, K.6
-
8
-
-
0032146727
-
Mendelian susceptibility to mycobacterial infection in man
-
8 Altare F, Jouanguy E, Lamhamedi S, Doffinger R, Fischer A, Casanova J-L. Mendelian susceptibility to mycobacterial infection in man. Curr Opin Immunol 1998; 10:413-417.
-
(1998)
Curr Opin Immunol
, vol.10
, pp. 413-417
-
-
Altare, F.1
Jouanguy, E.2
Lamhamedi, S.3
Doffinger, R.4
Fischer, A.5
Casanova, J.-L.6
-
9
-
-
0032925901
-
Differences between HLA-B44 and HLA-B60 in patients with smear-positive pulmonary tuberculosis and exposed controls
-
9 Bothamley GH. Differences between HLA-B44 and HLA-B60 in patients with smear-positive pulmonary tuberculosis and exposed controls. J Infect Dis 1999; 179:1051-1052.
-
(1999)
J Infect Dis
, vol.179
, pp. 1051-1052
-
-
Bothamley, G.H.1
-
10
-
-
0031739807
-
Parasite dose determines the Th1/Th2 nature of the response to Leishmania major independently of infection route and atrain of host or parasite
-
Building on their earlier work, the authors demonstrate that the dose of Leishmania parasite administered to an individual is a dominant factor in determining the Th1/ Th2 fate of the responding T cells
-
10 Menon JN, Bretscher PA. Parasite dose determines the Th1/Th2 nature of the response to Leishmania major independently of infection route and atrain of host or parasite. Eur J Immunol 1998; 28:4020-4028. Building on their earlier work, the authors demonstrate that the dose of Leishmania parasite administered to an individual is a dominant factor in determining the Th1/ Th2 fate of the responding T cells.
-
(1998)
Eur J Immunol
, vol.28
, pp. 4020-4028
-
-
Menon, J.N.1
Bretscher, P.A.2
-
11
-
-
0026781801
-
Establishment of stable cell mediated immunity that makes 'susceptible' mice resistant to Leishmania major
-
11 Bretscher PA, Wei G, Menon JN, Beilefeldt-Ohmann H. Establishment of stable cell mediated immunity that makes 'susceptible' mice resistant to Leishmania major. Science 1992; 257:539-542.
-
(1992)
Science
, vol.257
, pp. 539-542
-
-
Bretscher, P.A.1
Wei, G.2
Menon, J.N.3
Beilefeldt-Ohmann, H.4
-
12
-
-
0032033419
-
Cytokines induce the development of functionally heterogenous T helper cell subsets
-
12 O'Garra A. Cytokines induce the development of functionally heterogenous T helper cell subsets. Immunity 1998; 8:275-283.
-
(1998)
Immunity
, vol.8
, pp. 275-283
-
-
O'Garra, A.1
-
13
-
-
3643072843
-
Regulation of the activity of IFN-γ promoter elements during Th cell differentiation
-
An interesting article demonstrating regulation of IFNγ-gene expression through differential regulation of distinct promoter elements
-
13 Zhang F, Wang DZ, Boothby M, Penix L, Flavell RA, Aune TM. Regulation of the activity of IFN-γ promoter elements during Th cell differentiation. J Immunol 1998; 161:6105-6112. An interesting article demonstrating regulation of IFNγ-gene expression through differential regulation of distinct promoter elements.
-
(1998)
J Immunol
, vol.161
, pp. 6105-6112
-
-
Zhang, F.1
Wang, D.Z.2
Boothby, M.3
Penix, L.4
Flavell, R.A.5
Aune, T.M.6
-
14
-
-
0033556145
-
IL-12 is not required for induction of type 1 cytokine responses in viral infections
-
14 Oxenius A, Karrer U, Zinkernagel RM, Hengertner H. IL-12 is not required for induction of type 1 cytokine responses in viral infections. J Immunol 1999; 162:965-973.
-
(1999)
J Immunol
, vol.162
, pp. 965-973
-
-
Oxenius, A.1
Karrer, U.2
Zinkernagel, R.M.3
Hengertner, H.4
-
15
-
-
0032763495
-
An alternate pathway for type 1 T cell differentiation
-
15 Feng C, Watanabe S, Maruyama S, Suzuki G, Sato M, Furuta T, et al. An alternate pathway for type 1 T cell differentiation. International Immunology 1999; 11:1185-1194.
-
(1999)
International Immunology
, vol.11
, pp. 1185-1194
-
-
Feng, C.1
Watanabe, S.2
Maruyama, S.3
Suzuki, G.4
Sato, M.5
Furuta, T.6
-
16
-
-
0031058726
-
Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ T cells
-
16 Rincon M, Anguita J, Nakamura T, Fikrig E, Flavell RA. Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ T cells. J Exp Med 1997; 185:461-469.
-
(1997)
J Exp Med
, vol.185
, pp. 461-469
-
-
Rincon, M.1
Anguita, J.2
Nakamura, T.3
Fikrig, E.4
Flavell, R.A.5
-
17
-
-
0028346887
-
Induction of interleukin 4 (IL-4) expression in T helper (Th) cells is not dependent on IL-4 from non-Th cells
-
17 Schmitz J, Thiel A, Kuhn R, Rajewsky K, Muller W, Assenmacher M, Radbruch A. Induction of interleukin 4 (IL-4) expression in T helper (Th) cells is not dependent on IL-4 from non-Th cells. J Exp Med 1994; 179:1349-1353.
-
(1994)
J Exp Med
, vol.179
, pp. 1349-1353
-
-
Schmitz, J.1
Thiel, A.2
Kuhn, R.3
Rajewsky, K.4
Muller, W.5
Assenmacher, M.6
Radbruch, A.7
-
18
-
-
0031048039
-
Multiple pathways for the inititation of T helper 2 (Th2) responses
-
18 Coffman RL, Weid T. Multiple pathways for the inititation of T helper 2 (Th2) responses. J Exp Med 1997; 185:373-375.
-
(1997)
J Exp Med
, vol.185
, pp. 373-375
-
-
Coffman, R.L.1
Weid, T.2
-
19
-
-
0033166538
-
Dealing from the evolutionary pawnshop: How lymphocytes make decisions
-
Seder and Reiner discuss numerous mechanisms potentially involved in control of lymphocyte gene expression.
-
19 Reiner SL, Seder RA. Dealing from the evolutionary pawnshop: how lymphocytes make decisions. Immunity 1999; 11:1-10. Seder and Reiner discuss numerous mechanisms potentially involved in control of lymphocyte gene expression.
-
(1999)
Immunity
, vol.11
, pp. 1-10
-
-
Reiner, S.L.1
Seder, R.A.2
-
20
-
-
0033591298
-
Instruction, selection, or tampering with the odds?
-
20 Coffman RL, Reiner SL. Instruction, selection, or tampering with the odds? Science 1999; 284:1283-1285.
-
(1999)
Science
, vol.284
, pp. 1283-1285
-
-
Coffman, R.L.1
Reiner, S.L.2
-
21
-
-
0033618562
-
Host defense mechanisms triggered by microbial liproproteins through Toll-like receptors
-
This work demonstrates a clear role for Toll-like receptor 2 in as a receptor in lipoprotein directed IL-12 production by macrophages. The effect was independent of signalling through CD14
-
21 Brightbill HD, Libraty DM, Krutzik SR, Yang R-B, Belisle JT, Bleharsky JR, et al. Host defense mechanisms triggered by microbial liproproteins through Toll-like receptors. Science 1999; 285:732-735. This work demonstrates a clear role for Toll-like receptor 2 in as a receptor in lipoprotein directed IL-12 production by macrophages. The effect was independent of signalling through CD14.
-
(1999)
Science
, vol.285
, pp. 732-735
-
-
Brightbill, H.D.1
Libraty, D.M.2
Krutzik, S.R.3
Yang, R.-B.4
Belisle, J.T.5
Bleharsky, J.R.6
-
22
-
-
0032989460
-
Lipid A directly inhibits IL-4 production by murine Th2 cells but does not inhibit IFN-γ by Th1 cells
-
22 Watanabe T, Inoue T, Ochi H, Terashima M, Asano Y, Nakatani T. Lipid A directly inhibits IL-4 production by murine Th2 cells but does not inhibit IFN-γ by Th1 cells. Eur J Immunol 1999; 29:413-418.
-
(1999)
Eur J Immunol
, vol.29
, pp. 413-418
-
-
Watanabe, T.1
Inoue, T.2
Ochi, H.3
Terashima, M.4
Asano, Y.5
Nakatani, T.6
-
23
-
-
0033151919
-
Differential regulation of the IL-12 p40 promoter and of p40 secretion by CpG DNA and lipopolysaccharide
-
23 Cowdery JS, Boerth NJ, Norian LA, Myung PS, Koretzky GA. Differential regulation of the IL-12 p40 promoter and of p40 secretion by CpG DNA and lipopolysaccharide. J Immunol 1999; 162:6770-6775.
-
(1999)
J Immunol
, vol.162
, pp. 6770-6775
-
-
Cowdery, J.S.1
Boerth, N.J.2
Norian, L.A.3
Myung, P.S.4
Koretzky, G.A.5
-
24
-
-
0032910973
-
CpG-oligodeoxynucleotides co-stimulate primary T cells in the absence of antigen-presenting cells
-
The title speaks for itself. CpG oligodeoxynucleotides induced IL-2 and IL-2-receptor expression in T cells
-
24 Bendigs S, Salzer U, Lipford GB, Wagner H, Heeg K. CpG-oligodeoxynucleotides co-stimulate primary T cells in the absence of antigen-presenting cells. Eur J Immunol 1999; 29:1209-1208. The title speaks for itself. CpG oligodeoxynucleotides induced IL-2 and IL-2-receptor expression in T cells.
-
(1999)
Eur J Immunol
, vol.29
, pp. 1209-11208
-
-
Bendigs, S.1
Salzer, U.2
Lipford, G.B.3
Wagner, H.4
Heeg, K.5
-
25
-
-
0344604529
-
Differential regulation of macrophage interleukin-1 (IL-1), IL-12, and CD80-CD86 by two bacterial toxins
-
25 Foss DL, Zilliox MJ, Murtaugh MP. Differential regulation of macrophage interleukin-1 (IL-1), IL-12, and CD80-CD86 by two bacterial toxins. Infect Immun 1999; 67:5275-5281.
-
(1999)
Infect Immun
, vol.67
, pp. 5275-5281
-
-
Foss, D.L.1
Zilliox, M.J.2
Murtaugh, M.P.3
-
26
-
-
0033215423
-
Oligodeoxynucleotides containing palindrome sequences with internal 5′-CpG-3′ act directly on human NK and activated T cells to induce IFN-γ production in vitro
-
This work demonstrates the direct stimulatory effects of CpG oligodeoxynucleotides on T cells as well as NK cells
-
26 Iho S, Yamamoto T, Yamamoto S. Oligodeoxynucleotides containing palindrome sequences with internal 5′-CpG-3′ act directly on human NK and activated T cells to induce IFN-γ production in vitro. J Immunol 1999; 163:3642-3652. This work demonstrates the direct stimulatory effects of CpG oligodeoxynucleotides on T cells as well as NK cells.
-
(1999)
J Immunol
, vol.163
, pp. 3642-3652
-
-
Iho, S.1
Yamamoto, T.2
Yamamoto, S.3
-
27
-
-
0033214553
-
Mycobacterium tuberculosis inhibits IFN-γ transcriptional responses without inhibiting activation of STAT1
-
The results suggest a possible virulence mechanism for mycobacteria. It would be interesting to determine if less virulent strains of mycobacteria have a similar ability to suppress Th1 responses
-
27 Ting L-M, Kim AC, Cattamanchi A, Ernst JD. Mycobacterium tuberculosis inhibits IFN-γ transcriptional responses without inhibiting activation of STAT1. J Immunol 1999; 163:3898-3906. The results suggest a possible virulence mechanism for mycobacteria. It would be interesting to determine if less virulent strains of mycobacteria have a similar ability to suppress Th1 responses.
-
(1999)
J Immunol
, vol.163
, pp. 3898-3906
-
-
Ting, L.-M.1
Kim, A.C.2
Cattamanchi, A.3
Ernst, J.D.4
-
28
-
-
0033567089
-
Mycobacterium avium infections of mouse macrophages inhibits IFN-γ Janus kinase-STAT signalling and gene induction by down-regulation of the IFN-γ receptor
-
As in the previous article, this study demonstrates a possible virulence mechanism for mycobacteria
-
28 Hussain S, Zwilling BS, Lafuse WP. Mycobacterium avium infections of mouse macrophages inhibits IFN-γ Janus kinase-STAT signalling and gene induction by down-regulation of the IFN-γ receptor. J Immunol 1999; 163:2041-2048. As in the previous article, this study demonstrates a possible virulence mechanism for mycobacteria.
-
(1999)
J Immunol
, vol.163
, pp. 2041-2048
-
-
Hussain, S.1
Zwilling, B.S.2
Lafuse, W.P.3
-
29
-
-
0033041868
-
Retrovirally induced switch from production of IL-12 to IL-4 in dendritic cells
-
29 Kelleher P, Maroof A, Knight SC. Retrovirally induced switch from production of IL-12 to IL-4 in dendritic cells. Eur J Immunol 1999; 29:2309-2318.
-
(1999)
Eur J Immunol
, vol.29
, pp. 2309-2318
-
-
Kelleher, P.1
Maroof, A.2
Knight, S.C.3
-
30
-
-
0033179165
-
The interleukin-12-mediated pathway of immune events is dysfunctional in human immunodeficiency virus-infected individuals
-
Although primarily descriptive, these experiments demonstrate a defect in IL-12 production in peripheral blood mononuclear cells from HIV infected patients, leading to decrease in IFNγ-production from cells of these patients
-
30 Marshall JD, Chehimi J, Gri G, Kostman JR, Montaner LJ, Trinchieri G. The interleukin-12-mediated pathway of immune events is dysfunctional in human immunodeficiency virus-infected individuals. Blood 1999; 94:1003-1011. Although primarily descriptive, these experiments demonstrate a defect in IL-12 production in peripheral blood mononuclear cells from HIV infected patients, leading to decrease in IFNγ-production from cells of these patients.
-
(1999)
Blood
, vol.94
, pp. 1003-1011
-
-
Marshall, J.D.1
Chehimi, J.2
Gri, G.3
Kostman, J.R.4
Montaner, L.J.5
Trinchieri, G.6
-
31
-
-
0032921744
-
Regulation of macrophage IL-12 synthesis by leishmania phosphoglycans
-
31 Piedrafita D, Proudfoot L, Nikolaev AV, Xu D, Sands W, Feng G-J, et al. Regulation of macrophage IL-12 synthesis by leishmania phosphoglycans. Eur J Immunol 1999; 29:235-244.
-
(1999)
Eur J Immunol
, vol.29
, pp. 235-244
-
-
Piedrafita, D.1
Proudfoot, L.2
Nikolaev, A.V.3
Xu, D.4
Sands, W.5
Feng, G.-J.6
-
32
-
-
0033068180
-
- subclasses of dendritic cells direct the development of distinct T helper cells in vivo
-
In addition to showing that distinct dendritic cell subclasses induce distinct responses in T cells, this study also demonstrates that the dendritic cells themselves show differential expression of IL-12, thus providing a mechanism for their differential influence over Th cells
-
- subclasses of dendritic cells direct the development of distinct T helper cells in vivo. J Exp Med 1999; 189:587-592. In addition to showing that distinct dendritic cell subclasses induce distinct responses in T cells, this study also demonstrates that the dendritic cells themselves show differential expression of IL-12, thus providing a mechanism for their differential influence over Th cells.
-
(1999)
J Exp Med
, vol.189
, pp. 587-592
-
-
Maldonado-Lopez, R.1
Smedt, T.D.2
Michel, P.3
Godfroid, J.4
Pajak, B.5
Heirman, C.6
-
33
-
-
0033514364
-
Distinct dendritic cell subsets differentially regulate the class of immune response in vivo
-
33 Pulendran B, Smith JL, Caspary G, Brasel K, Pettit D, Maraskovsky E, Maliszewaki CR. Distinct dendritic cell subsets differentially regulate the class of immune response in vivo. Proc Natl Acad Sci USA 1999; 98:1036-1041.
-
(1999)
Proc Natl Acad Sci USA
, vol.98
, pp. 1036-1041
-
-
Pulendran, B.1
Smith, J.L.2
Caspary, G.3
Brasel, K.4
Pettit, D.5
Maraskovsky, E.6
Maliszewaki, C.R.7
-
34
-
-
0033582629
-
Reciprocal control of T helper cell and dendritic cell differentiation
-
34 Rissoan M-C, Soumelis V, Kadowaki N, Grouard G, Briere F, de Waal Malefyt R, Liu Y-J. Reciprocal control of T helper cell and dendritic cell differentiation. Science 1999; 283:1183-1186.
-
(1999)
Science
, vol.283
, pp. 1183-1186
-
-
Rissoan, M.-C.1
Soumelis, V.2
Kadowaki, N.3
Grouard, G.4
Briere, F.5
De Waal Malefyt, R.6
Liu, Y.-J.7
-
35
-
-
0033067374
-
Susceptibility or resistance to Leishmania infection is dictated by the macrophages evolved under the influence of IL-3 or GM-CSF
-
35 Saha B, Saini A, Germond R, Perrin PJ, Harlan DM, Davis TA. Susceptibility or resistance to Leishmania infection is dictated by the macrophages evolved under the influence of IL-3 or GM-CSF. Eur J Immunol 1999; 29:2319-2329.
-
(1999)
Eur J Immunol
, vol.29
, pp. 2319-2329
-
-
Saha, B.1
Saini, A.2
Germond, R.3
Perrin, P.J.4
Harlan, D.M.5
Davis, T.A.6
-
36
-
-
0031775744
-
Resting respiratory tract dendritic cells preferentially stimulate T helper cell type 2 (Th2) responses and require obligatory cytokine signals for induction of Th1 immunity
-
36 Stumbles PA, Thomas JA, Pimm CL, Lee PT, Venaille TJ, Proksch S, Holt PG. Resting respiratory tract dendritic cells preferentially stimulate T helper cell type 2 (Th2) responses and require obligatory cytokine signals for induction of Th1 immunity. J Exp Med 1998; 188:2019-2031.
-
(1998)
J Exp Med
, vol.188
, pp. 2019-2031
-
-
Stumbles, P.A.1
Thomas, J.A.2
Pimm, C.L.3
Lee, P.T.4
Venaille, T.J.5
Proksch, S.6
Holt, P.G.7
-
37
-
-
0033486007
-
T-cell priming by type-1 and type-2 polarized dendritic cells: The concept of a third signal
-
37 Kalinski P, Hilkens CMU, Wierenge EA, Kapsenberg ML. T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signal. Immunol Today 1999; 20:551-567.
-
(1999)
Immunol Today
, vol.20
, pp. 551-567
-
-
Kalinski, P.1
Hilkens, C.M.U.2
Wierenge, E.A.3
Kapsenberg, M.L.4
-
38
-
-
0032774865
-
Coinfection with Toxoplasma gondii inhibits antigen-specific Th2 immune responses, tissue inflammation, and parasitism in BALB/c mice infected with Leishmania major
-
In this study, acute but not chronic infections with T. gondii were able to influence the immune response to L. major emphasizing that only in an overwhelming response are such influences likely to occur. In addition, T. gondii infection had no influence on already established immune response to L. major indicating that such influence is involved in the early inductive stage of the imune response
-
38 Santiago HC, Oliveira MAP, Bambirra EA, Faria AMC, Afonso LCC, Vieira LQ, Gazzinelli RT. Coinfection with Toxoplasma gondii inhibits antigen-specific Th2 immune responses, tissue inflammation, and parasitism in BALB/c mice infected with Leishmania major. Infect Immun 1999; 67:4939-4944. In this study, acute but not chronic infections with T. gondii were able to influence the immune response to L. major emphasizing that only in an overwhelming response are such influences likely to occur. In addition, T. gondii infection had no influence on already established immune response to L. major indicating that such influence is involved in the early inductive stage of the imune response.
-
(1999)
Infect Immun
, vol.67
, pp. 4939-4944
-
-
Santiago, H.C.1
Oliveira, M.A.P.2
Bambirra, E.A.3
Faria, A.M.C.4
Afonso, L.C.C.5
Vieira, L.Q.6
Gazzinelli, R.T.7
-
40
-
-
0028089795
-
Differential effects of blockade of CD28-B7 on the development of Th1 or Th2 effector cells in experimental Leishmaniasis
-
40 Corry DB, Reiner SL, Linsley PS, Locksley RM. Differential effects of blockade of CD28-B7 on the development of Th1 or Th2 effector cells in experimental Leishmaniasis. J Immunol 1994; 153:4142-4148.
-
(1994)
J Immunol
, vol.153
, pp. 4142-4148
-
-
Corry, D.B.1
Reiner, S.L.2
Linsley, P.S.3
Locksley, R.M.4
-
41
-
-
0031740995
-
Mycobacterial dose defines the Th1/Th2 nature of the immune response independently of whether immunization is administered by the intravenous subcutaneous or intradermal route
-
The Th1/Th1 fate of cells responding to mycobacterial infection is dramatically dependent on the initial number of infecting bacteria. As this is also seen in Leishmania infection, it appears to represent a general rule for slow-growing intracellular organisms
-
41 Power C, Wei G, Bretscher P. Mycobacterial dose defines the Th1/Th2 nature of the immune response independently of whether immunization is administered by the intravenous subcutaneous or intradermal route. Infect Immun 1998; 66:5743-5750. The Th1/Th1 fate of cells responding to mycobacterial infection is dramatically dependent on the initial number of infecting bacteria. As this is also seen in Leishmania infection, it appears to represent a general rule for slow-growing intracellular organisms.
-
(1998)
Infect Immun
, vol.66
, pp. 5743-5750
-
-
Power, C.1
Wei, G.2
Bretscher, P.3
-
42
-
-
0031739697
-
CTLA4 (CD152) modulates the Th subset response and alters the course of experimental Leishmania major infection
-
42 Saha B, Chattopadhyay S, Germond R, Harlan DM, Perrin PJ. CTLA4 (CD152) modulates the Th subset response and alters the course of experimental Leishmania major infection. Eur J Immunol 1998; 28:4213-4220.
-
(1998)
Eur J Immunol
, vol.28
, pp. 4213-4220
-
-
Saha, B.1
Chattopadhyay, S.2
Germond, R.3
Harlan, D.M.4
Perrin, P.J.5
-
43
-
-
0032143821
-
Helper T cell differentiation is controlled by the cell cycle
-
This is a seminal article demonstrating a role for cell cycle and cell division in controlling IFNγ, IL-2 and IL-4 cytokine expression from T helper cells
-
43 Bird JJ, Brown DR, Mullen AC, et al. Helper T cell differentiation is controlled by the cell cycle. Immunity 1998; 9:229-337. This is a seminal article demonstrating a role for cell cycle and cell division in controlling IFNγ, IL-2 and IL-4 cytokine expression from T helper cells.
-
(1998)
Immunity
, vol.9
, pp. 229-337
-
-
Bird, J.J.1
Brown, D.R.2
Mullen, A.C.3
-
44
-
-
0032482996
-
Cell division regulates the T cell cytokine repertoire, revealing a mechanism underlying immune class regulation
-
In addition to those discussed in the previous paper, this work demonstrates cell-division dependency for production of IL-5 and IL-10
-
44 Gett AV, Hodgkin PD. Cell division regulates the T cell cytokine repertoire, revealing a mechanism underlying immune class regulation. Proc Natl Acad Sci USA 1995; 95:9488-9493. In addition to those discussed in the previous paper, this work demonstrates cell-division dependency for production of IL-5 and IL-10.
-
(1995)
Proc Natl Acad Sci USA
, vol.95
, pp. 9488-9493
-
-
Gett, A.V.1
Hodgkin, P.D.2
-
45
-
-
84991197370
-
The relationship between humoral and cell-mediated immunity
-
45 Parish CR. The relationship between humoral and cell-mediated immunity. Trans Rev 1972; 13:35-66.
-
(1972)
Trans Rev
, vol.13
, pp. 35-66
-
-
Parish, C.R.1
-
46
-
-
0030760776
-
Pathogenesis of tuberculosis in mice exposed to low and high doses of an environmental Mycobacterial Saprophyte before infection
-
46 Hernandez-Pando R, Pavon L, Arriaga K, Orozco H, Madrid-Marina V, Rook G. Pathogenesis of tuberculosis in mice exposed to low and high doses of an environmental Mycobacterial Saprophyte before infection. Infect Immun 1997; 65:3317-3327.
-
(1997)
Infect Immun
, vol.65
, pp. 3317-3327
-
-
Hernandez-Pando, R.1
Pavon, L.2
Arriaga, K.3
Orozco, H.4
Madrid-Marina, V.5
Rook, G.6
-
47
-
-
0033558365
-
TCR-independent pathways mediate the effects of antigen dose and altered peptide ligands on Th cell polarization
-
47 Grakoui A, Donermeyer DL, Kanagawa O, Murphy KM, Allen PM. TCR-independent pathways mediate the effects of antigen dose and altered peptide ligands on Th cell polarization. J Immunol 1999; 162:1923-1930.
-
(1999)
J Immunol
, vol.162
, pp. 1923-1930
-
-
Grakoui, A.1
Donermeyer, D.L.2
Kanagawa, O.3
Murphy, K.M.4
Allen, P.M.5
-
48
-
-
0033179403
-
Peptide dose, affinity, and time of differentiation can contribute to the Th1/Th2 cytokine balance
-
The authors have shown that Th1 responses can be achieved with low antigen (peptide) doses in a transgenic mouse system
-
48 Rogers PR, Croft M. Peptide dose, affinity, and time of differentiation can contribute to the Th1/Th2 cytokine balance. J Immunol 1999; 163:1205-1213. The authors have shown that Th1 responses can be achieved with low antigen (peptide) doses in a transgenic mouse system.
-
(1999)
J Immunol
, vol.163
, pp. 1205-1213
-
-
Rogers, P.R.1
Croft, M.2
-
49
-
-
0028067787
-
Transfer of CD4+ T cells to C.B-17 SCID mice: A model to study Th1 and Th2 cell differentiation and regulation in vivo
-
49 Powrie F, Coffman RL, Corres-Oliveira R. Transfer of CD4+ T cells to C.B-17 SCID mice: a model to study Th1 and Th2 cell differentiation and regulation in vivo. 58th Forum in Immunology 1994:347-353.
-
(1994)
58th Forum in Immunology
, pp. 347-353
-
-
Powrie, F.1
Coffman, R.L.2
Corres-Oliveira, R.3
-
50
-
-
0019720353
-
Resistance and abrogation of resistance to cutaneous leishmaniasis in reconstituted Balb/c nude mice
-
50 Mitchell GF, Curtis JM, Scollay RG, Handman E. Resistance and abrogation of resistance to cutaneous leishmaniasis in reconstituted Balb/c nude mice. AJEBAK 1981; 59:539-554.
-
(1981)
AJEBAK
, vol.59
, pp. 539-554
-
-
Mitchell, G.F.1
Curtis, J.M.2
Scollay, R.G.3
Handman, E.4
-
51
-
-
0001019516
-
Quantitative considerations in the design of vaccination strategies against pathogens uniquely susceptible to cell mediated attack
-
Kaufmann SHE. (editor). Berlin and New York: de Gruyter
-
51 Bretscher PA. Quantitative considerations in the design of vaccination strategies against pathogens uniquely susceptible to cell mediated attack. In: Concepts in vaccine development. Kaufmann SHE. (editor). Berlin and New York: de Gruyter; 1996. pp. 187-204.
-
(1996)
Concepts in Vaccine Development
, pp. 187-204
-
-
Bretscher, P.A.1
-
52
-
-
0031014668
-
The inverse association between tuberculin responses and atopic disorder
-
52 Shirakawa T, Enomoto T, Shimazu A, Hopkin JM. The inverse association between tuberculin responses and atopic disorder. Science 1997; 275:77-79.
-
(1997)
Science
, vol.275
, pp. 77-79
-
-
Shirakawa, T.1
Enomoto, T.2
Shimazu, A.3
Hopkin, J.M.4
-
53
-
-
0031782864
-
BCG infection suppresses allergic sensitization and development of increased airway reactivity in an animal model
-
53 Herz U, Gerhold K, Gruber C, Braun A, Wahn U, Renz H, Paul K. BCG infection suppresses allergic sensitization and development of increased airway reactivity in an animal model. J. Allergy Clin Immunol 1998; 102:867-874.
-
(1998)
J. Allergy Clin Immunol
, vol.102
, pp. 867-874
-
-
Herz, U.1
Gerhold, K.2
Gruber, C.3
Braun, A.4
Wahn, U.5
Renz, H.6
Paul, K.7
-
54
-
-
0032878131
-
Fasciola hepatica suppresses a protective Th1 response against Bordetella pertussis
-
Interestingly, in this study the helminth infection suppressed an ongoing Th1 response to B. pertussis infection, suggesting a mechanism which is qualitatively different from that involved in the supression of Th2 responses by Toxoplasma parasites
-
54 Brady MT, O'Neill SM, Dalton JP, Mills KHG. Fasciola hepatica suppresses a protective Th1 response against Bordetella pertussis. Infect Immun 1999; 67:5372-5378. Interestingly, in this study the helminth infection suppressed an ongoing Th1 response to B. pertussis infection, suggesting a mechanism which is qualitatively different from that involved in the supression of Th2 responses by Toxoplasma parasites.
-
(1999)
Infect Immun
, vol.67
, pp. 5372-5378
-
-
Brady, M.T.1
O'Neill, S.M.2
Dalton, J.P.3
Mills, K.H.G.4
-
55
-
-
0033152035
-
Helminth- and Bacillus Calmette-Guerin-induced immunity in children sensitized in utero to Fllariasis and Schistosomiasis
-
55 Malhotra I, Mungai P, Wamachi A, Kioko Ouma JH, Kazura JW, King CL. Helminth- and Bacillus Calmette-Guerin-induced immunity in children sensitized in utero to Fllariasis and Schistosomiasis. J Immunol 1999; 162:6843-6848.
-
(1999)
J Immunol
, vol.162
, pp. 6843-6848
-
-
Malhotra, I.1
Mungai, P.2
Wamachi, A.3
Kioko Ouma, J.H.4
Kazura, J.W.5
King, C.L.6
-
56
-
-
0032808890
-
Onchoceroiasis modulates the immune response to mycobacterial antigens
-
56 Stewart GR, Boussinesq M, Coulson T, Nutman ET, Bradley JE. Onchoceroiasis modulates the immune response to mycobacterial antigens. Clin Exp Med 1999; 117:517-523.
-
(1999)
Clin Exp Med
, vol.117
, pp. 517-523
-
-
Stewart, G.R.1
Boussinesq, M.2
Coulson, T.3
Nutman, E.T.4
Bradley, J.E.5
-
57
-
-
0032736499
-
The Th1/Th2 nature of concurrent immune responses to unrelated antigens can be independent
-
Using xenogenic red blood cells as a complex non-replicating antigen, the authors demonstrate that the immune responses to non-crossreacting antigens occurring simultaneously in the same lymphoid organ can develop independently
-
57 Ismail N, Bretscher P. The Th1/Th2 nature of concurrent immune responses to unrelated antigens can be independent. J Immunol 1999; 163:4842-4850. Using xenogenic red blood cells as a complex non-replicating antigen, the authors demonstrate that the immune responses to non-crossreacting antigens occurring simultaneously in the same lymphoid organ can develop independently.
-
(1999)
J Immunol
, vol.163
, pp. 4842-4850
-
-
Ismail, N.1
Bretscher, P.2
|