-
1
-
-
0001326511
-
Are we approaching the end of the antibiotic era?
-
Hancock, R.E.W, and Knowles, D. (1998) Are we approaching the end of the antibiotic era? Curr. Opin. Microbiol. 1, 493-494
-
(1998)
Curr. Opin. Microbiol.
, vol.1
, pp. 493-494
-
-
Hancock, R.E.W.1
Knowles, D.2
-
2
-
-
0033082528
-
How antibiotics cause antibiotic resistance
-
Heinemann, J.A. (1999) How antibiotics cause antibiotic resistance. Drug Discovery Today 4, 72-79
-
(1999)
Drug Discovery Today
, vol.4
, pp. 72-79
-
-
Heinemann, J.A.1
-
3
-
-
0032134269
-
Novel approaches to the discovery of antimicrobial agents
-
Schmid, M.B. (1998) Novel approaches to the discovery of antimicrobial agents. Curr. Opin. Chem. Biol. 2, 529-534
-
(1998)
Curr. Opin. Chem. Biol.
, vol.2
, pp. 529-534
-
-
Schmid, M.B.1
-
4
-
-
0030667760
-
Will combinatorial chemistry deliver real medicines?
-
Myers, P.L. (1997) Will combinatorial chemistry deliver real medicines? Curr. Opin. Biotechnol. 8, 701-707
-
(1997)
Curr. Opin. Biotechnol.
, vol.8
, pp. 701-707
-
-
Myers, P.L.1
-
5
-
-
0030707561
-
Will natural products remain an important source of drug research for the future?
-
Nisbet, L.J. and Moore, M. (1997) Will natural products remain an important source of drug research for the future? Curr. Opin. Biotechnol. 8, 708-712
-
(1997)
Curr. Opin. Biotechnol.
, vol.8
, pp. 708-712
-
-
Nisbet, L.J.1
Moore, M.2
-
6
-
-
0001025490
-
Transposable element tools for microbial genetics
-
(Neidhardt F.C. ed.), ASM Press
-
Berg, C.M. and Berg, D.A. (1996) Transposable element tools for microbial genetics. In Escherichia coli and Salmonella (Neidhardt F.C. ed.), pp. 2588-2612, ASM Press
-
(1996)
Escherichia Coli and Salmonella
, pp. 2588-2612
-
-
Berg, C.M.1
Berg, D.A.2
-
7
-
-
0024354604
-
Genetic analysis of temperature-sensitive lethal mutants of Salmonella typhimurium
-
Schmid, M.B. et al. (1989) Genetic analysis of temperature-sensitive lethal mutants of Salmonella typhimurium. Genetics 123, 625-633
-
(1989)
Genetics
, vol.123
, pp. 625-633
-
-
Schmid, M.B.1
-
8
-
-
0032555218
-
Systematic identification of essential genes by in vitro mariner mutagenesis
-
Akerley, B.J. et al. (1998) Systematic identification of essential genes by in vitro mariner mutagenesis. Proc. Natl. Acad. Sci. U. S. A. 95, 8927-8932
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 8927-8932
-
-
Akerley, B.J.1
-
9
-
-
0028031548
-
Efficient integration of artificial transposons into plasmid targets in vitro. A useful tool for DNA mapping, sequencing and genetic analysis
-
Devine, S.E. and Boeke, J.D. (1994) Efficient integration of artificial transposons into plasmid targets in vitro. A useful tool for DNA mapping, sequencing and genetic analysis. Nucleic Acids Res. 22, 3765-3772
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 3765-3772
-
-
Devine, S.E.1
Boeke, J.D.2
-
10
-
-
0029117137
-
Simultaneous identification of bacterial virulence genes by negative selection
-
Hensel, M. et al. (1995) Simultaneous identification of bacterial virulence genes by negative selection. Science 269, 400-403
-
(1995)
Science
, vol.269
, pp. 400-403
-
-
Hensel, M.1
-
11
-
-
0031784044
-
A genome-based approach for the identification of essential bacterial genes
-
Arigoni, F. et al. (1998) A genome-based approach for the identification of essential bacterial genes. Nat. Biotechnol. 16, 851-856
-
(1998)
Nat. Biotechnol.
, vol.16
, pp. 851-856
-
-
Arigoni, F.1
-
12
-
-
0029789824
-
A minimal gene set for cellular life derived by comparison of complete bacterial genomes
-
Mushegian, A.R. and Koonin, E.V. (1996) A minimal gene set for cellular life derived by comparison of complete bacterial genomes. Proc. Natl. Acad. Sci. U. S. A. 93, 10268-10273
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 10268-10273
-
-
Mushegian, A.R.1
Koonin, E.V.2
-
13
-
-
0030660581
-
A genomic perspective on protein families
-
Tatusov, R.L. et al. (1997) A genomic perspective on protein families. Science 278, 631-637
-
(1997)
Science
, vol.278
, pp. 631-637
-
-
Tatusov, R.L.1
-
14
-
-
0032953228
-
Comparative genomes of Chlamydia pneumoniae and C. trachomatis
-
Kalman, S. et al. (1999) Comparative genomes of Chlamydia pneumoniae and C. trachomatis. Nat. Genet. 21, 385-389
-
(1999)
Nat. Genet.
, vol.21
, pp. 385-389
-
-
Kalman, S.1
-
15
-
-
0032173615
-
Comparative mycobacterial genomics
-
Cole, S.T. (1998) Comparative mycobacterial genomics. Curr. Opin. Microbiol. 1, 567-571
-
(1998)
Curr. Opin. Microbiol.
, vol.1
, pp. 567-571
-
-
Cole, S.T.1
-
16
-
-
0033552961
-
Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori
-
Alm, R.A. et al. (1999) Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori. Nature 397, 176-180
-
(1999)
Nature
, vol.397
, pp. 176-180
-
-
Alm, R.A.1
-
17
-
-
0033612136
-
Comparative genomics of BCG vaccines by whole-genome DNA microarray
-
Behr, M.A. et al. (1999) Comparative genomics of BCG vaccines by whole-genome DNA microarray. Science 284, 1520-1523
-
(1999)
Science
, vol.284
, pp. 1520-1523
-
-
Behr, M.A.1
-
18
-
-
0025183708
-
Basic local alignment search tool
-
Altschul S.F. et al. (1990) Basic local alignment search tool. J. Mol. Biol. 215, 403-410
-
(1990)
J. Mol. Biol.
, vol.215
, pp. 403-410
-
-
Altschul, S.F.1
-
19
-
-
0033168258
-
Integrated pathway-genome databases and their role in drug discovery
-
Karp, P.D. et al. (1999) Integrated pathway-genome databases and their role in drug discovery. Trends Biotechnol. 17, 275-281
-
(1999)
Trends Biotechnol.
, vol.17
, pp. 275-281
-
-
Karp, P.D.1
-
20
-
-
0030681279
-
The Escherichia coli genome sequence: The end of an era or the start of the FUN?
-
Hinton, J.C.D. (1997) The Escherichia coli genome sequence: The end of an era or the start of the FUN? Mol. Microbiol. 26, 417-422
-
(1997)
Mol. Microbiol.
, vol.26
, pp. 417-422
-
-
Hinton, J.C.D.1
-
21
-
-
15444350252
-
The complete genome sequence of Escherichia coli K-12
-
Blattner, F.R. et al. (1997) The complete genome sequence of Escherichia coli K-12. Science 277, 1453-1462
-
(1997)
Science
, vol.277
, pp. 1453-1462
-
-
Blattner, F.R.1
-
23
-
-
9444236174
-
Small peptides as potent mimetics of the protein hormone erythropoietin
-
Wrighton, N.C. (1996) Small peptides as potent mimetics of the protein hormone erythropoietin. Science 273, 458-464
-
(1996)
Science
, vol.273
, pp. 458-464
-
-
Wrighton, N.C.1
-
24
-
-
0034092470
-
Detection of small-molecule enzyme inhibitors with peptides isolated from phage displayed combinatorial peptide libraries
-
Hyde-DeRuyscher et al. (1999) Detection of small-molecule enzyme inhibitors with peptides isolated from phage displayed combinatorial peptide libraries. Chem. Biol. 7, 17-25
-
(1999)
Chem. Biol.
, vol.7
, pp. 17-25
-
-
Hyde-DeRuyscher1
-
25
-
-
0029876415
-
Genetic selection of peptide aptamers that recognize and inhibit cyclin-dependent kinase 2
-
Colas, P. et al. (1996) Genetic selection of peptide aptamers that recognize and inhibit cyclin-dependent kinase 2. Nature 380, 548-550
-
(1996)
Nature
, vol.380
, pp. 548-550
-
-
Colas, P.1
-
26
-
-
0032564350
-
An artificial cell cycle inhibitor isolated from a combinatorial library
-
Cohen, B.A. et al. (1998) An artificial cell cycle inhibitor isolated from a combinatorial library. Proc. Natl. Acad. Sci. U. S. A. 95, 14272-14277
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 14272-14277
-
-
Cohen, B.A.1
-
27
-
-
0032564418
-
Targeting cyclin-dependent kinases in Drosophila with peptide aptamers
-
Kolonin, M.G. and Finley, R.L. (1998) Targeting cyclin-dependent kinases in Drosophila with peptide aptamers. Proc. Natl. Acad. Sci. U. S. A. 95, 14266-14271
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 14266-14271
-
-
Kolonin, M.G.1
Finley, R.L.2
-
28
-
-
0032404491
-
The impact of two-hybrid and related methods on biotechnology
-
Colas, P. and Brent, R. (1998) The impact of two-hybrid and related methods on biotechnology. Trends Biotechnol. 16, 355-363
-
(1998)
Trends Biotechnol.
, vol.16
, pp. 355-363
-
-
Colas, P.1
Brent, R.2
-
29
-
-
0027255909
-
Elimination of false positives that arise in using the two-hybrid system
-
Bartel, P. et al. (1993) Elimination of false positives that arise in using the two-hybrid system. Biotechniques 14, 920-924
-
(1993)
Biotechniques
, vol.14
, pp. 920-924
-
-
Bartel, P.1
-
30
-
-
0031472251
-
A yeast genetic system for selecting small molecule inhibitors of protein-protein interactions in nanodroplets
-
Huang, J. and Schreiber, S.L. (1997) A yeast genetic system for selecting small molecule inhibitors of protein-protein interactions in nanodroplets. Proc. Natl. Acad. Sci. U. S. A. 94, 13396-13401
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 13396-13401
-
-
Huang, J.1
Schreiber, S.L.2
-
31
-
-
0030862012
-
Automated array technologies for gene expression profiling
-
Maier, E. et al. (1997) Automated array technologies for gene expression profiling. Drug Discovery Today 2, 315-324
-
(1997)
Drug Discovery Today
, vol.2
, pp. 315-324
-
-
Maier, E.1
-
32
-
-
0032563315
-
Exploiting chemical libraries, structure and genomics in the search for kinase inhibitors
-
Gray, N.S. et al. (1998) Exploiting chemical libraries, structure and genomics in the search for kinase inhibitors. Science 281, 533-538
-
(1998)
Science
, vol.281
, pp. 533-538
-
-
Gray, N.S.1
-
33
-
-
0033607188
-
Exploring drug-induced alterations in gene expression in Mycobacterium tuberculosis by microarray hybridization
-
Wilson, M. et al. (1999) Exploring drug-induced alterations in gene expression in Mycobacterium tuberculosis by microarray hybridization. Proc. Natl. Acad. Sci. U. S. A. 96, 12833-12838
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 12833-12838
-
-
Wilson, M.1
-
34
-
-
0032538603
-
Microchip arrays put DNA on the spot
-
Service, R.F. (1998) Microchip arrays put DNA on the spot. Science 282, 396-399
-
(1998)
Science
, vol.282
, pp. 396-399
-
-
Service, R.F.1
-
35
-
-
0032901303
-
Microarrays and toxicology: The advent of toxicogenomics
-
Nuwaysir, E.F. et al. (1999) Microarrays and toxicology: The advent of toxicogenomics. Mol. Carcinog. 24, 153-159
-
(1999)
Mol. Carcinog.
, vol.24
, pp. 153-159
-
-
Nuwaysir, E.F.1
-
36
-
-
0032948177
-
A human IFNGR1 small deletion hotspot associated with dominant susceptibility to mycobacterial infection
-
Jouanguy, E. et al. (1999) A human IFNGR1 small deletion hotspot associated with dominant susceptibility to mycobacterial infection. Nat. Genet. 21, 370-378
-
(1999)
Nat. Genet.
, vol.21
, pp. 370-378
-
-
Jouanguy, E.1
|