Does atopic disease start in foetal life?

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 55, Issue 1, 2000, Pages 2-10

  Jones, C A ^a,b   Holloway, J A ^a   Warner, J O ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G;

ATOPY; AUTOIMMUNE DISEASE; DISEASE PREDISPOSITION; FETUS; HUMAN; IMMUNE RESPONSE; IMMUNOGLOBULIN PRODUCTION; INTESTINE FLORA; PATHOGENESIS; PREGNANCY; PRENATAL DEVELOPMENT; PRIORITY JOURNAL; REVIEW;

ALLERGENS; AMNIOTIC FLUID; ANTIGENS; DIGESTIVE SYSTEM; EMBRYONIC AND FETAL DEVELOPMENT; FEMALE; FETUS; HUMANS; HYPERSENSITIVITY, IMMEDIATE; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; INFANT; INFANT, NEWBORN; MILK, HUMAN; PLACENTA; PREGNANCY;

EID: 0033971261     PISSN: 01054538     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1398-9995.2000.00109.x     Document Type: Review

References (80)

1. 1. HOLGATE ST. The cellular and mediator basis of asthma in relation to natural history. Lancet 1997;350:5-9.
2. 2. VON MUTIUS E. The rising trends in asthma and allergic disease. Clin Exp Allergy 1998;28 Suppl 5:45-49.
3. 3. CRONER S, KJELLMAN N-IM, ERIKSSON B, ROTH A. IgE screening in 1701 newborn infants and the development of atopic disease during pregnancy. Arch Dis Child 1982;57:364-368.
4. 4. MAGNUSSON CGM. Cord serum IgE in relation to family history of atopic disease in early infancy. Allergy 1988;43:241-251.
5. 5. MICHEL FB, BOUSQUET J, GREILLER P, ROBINET-LEVY M, COULOMB Y. Comparison of cord blood immunoglobulin E concentrations and maternal allergy for the prediction of atopic diseases in infancy. J Allergy Clin Immunol 1980;65:422-430.
6. 6. HALONEN M, STERN D, TAUSSIG LM, et al. The predictive relationship between serum IgE levels at birth and subsequent incidences of lower respiratory illnesses and eczema in infants. Am Rev Respir Dis 1992;146:866-870.
7. 7. WARNER JA, MILES EA, JONES AC, QUINT DJ, COLWELL BM, WARNER JO. Is deficiency of interferon gamma production by allergen triggered cord blood cells a predictor of atopic eczema? Clin Exp Allergy 1994;24:423-430.
8. 8. VAN DUREN-SCHMIDT K, PICHLER J, EBNER C, et al. Prenatal contact with inhalant allergens. Pediatr Res 1997;41:128-131.
9. 9. SZEPFALUSI Z, NENTWICH I, GERSTMAYR M, et al. Prenatal allergen contact with milk proteins. Clin Exp Allergy 1997;27:28-35.
10. 10. PRESCOTT SL, MACAUBAS C, HOLT BJ, et al. Transplacental priming of the human immune system to environmental allergens: universal skewing of initial T cell responses towards the Th2-cytokine profile. J Immunol 1998;160:4730-4737.
11. 11. Ruiz RGG, KEMENY DM, PRICE JF. Higher risk of infantile atopic dermatitis from maternal atopy than from paternal atopy. Clin Exp Allergy 1992;22:762-766.
12. 12. JOHNSON CC, OWNBY DR, PETERSON EL. Parental history of atopic disease and concentration of cord blood IgE. Clin Exp Allergy 1996;26:624-629.
13. 13. BERGMANN KE, BERGMANN RL, SCHULZ J, GRAB T, WAHN U. Prediction of atopic disease in the newborn: methodological aspects. Clin Exp Allergy 1990;20:21-26.
14. 14. BERGMANN RL, EDENHARTER G, BERGMANN KE, et al. Predictability of early atopy by cord blood-IgE and parental history. Clin Exp Allergy 1997;27:752-760.
15. 15. CARTER CO. Genetics of common disorders. Br Med Bull 1969;25:52-57.
16. 16. BARKER DJP, editor. Fetal and infant origins of adult disease. London: British Medical Journal, 1992.
17. 17. DIMMETTE JE. Studies of human pregnancy. I. Immunoglobulins attached to the trophoblast. Obstet Gynecol 1976;47:730-732.
18. 18. MILLER DL, HIRVONEN T, GITLIN D. Synthesis of IgE by the human conceptus. J Allergy Clin Immunol 1973;52:182-188.
19. 19. KING CL, MALHOTRA I, MUNGAI P, et al. B cell sensitisation to helminthic infection develops in utero in humans. J Immunol 1998;160:3578-3584.
20. 20. WEIL GJ, HUSSAIN R, KUMARASWAMI V, TRIPATHY SP, PHILLIPS KSD, OTTESEN EA. Prenatal allergic sensitisation to helminth antigens in the offspring of parasite infected mothers. J Clin Invest 1983;71:1124-1129.
21. 21. PASTORELLI G, ROUSSET F, PENE J, et al. Cord blood B cells are mature in their capacity to switch to IgE-producing cells in response to interleukin-4 in vitro. Clin Exp Immunol 1990;82:114-119.
22. 22. MiGUEZ-BURBANO MJ, HUTTO C, SHOR-POSNER G, et al. IgE-based assay for early detection of HIV-1 infection in infants. Lancet 1997;350:782-783.
23. 23. BERGMANN RL, SCHULZ J, GUNTHER S, et al. Determinants of cord-blood IgE concentrations in 6401 German neonates. Allergy 1995;50:65-71.
24. 24. COOKSON WOCM, YOUNG EP, SANDFORD AJ, et al. Maternal inheritance of atopic IgE responsiveness on chromosome 11q. Lancet 1992;340:381-384.
25. 25. RIDGE JP, FUCHS EJ, MATZINGER P. Neonatal tolerance revisited: turning on newborn T cells with dendritic cells. Science 1996;271:1723-1726.
26. 26. SARZOTTI M, ROBBINS DS, HOFFMAN PM. Induction of protective CTL responses in newborn mice by a murine retrovirus. Science 1996;271:1726-1728.
27. 27. FORSTHUBER T, YIP HC, LEHMANN PV. Induction of Th1 and Th2 immunity in neonatal mice. Science 1996;271:1728-1730.
28. 28. SUDO N, SAWAMURA S, TANAKA K, AIBA Y, KUBO C, KOGA Y. The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction. J Immunol 1997;159:1739-1745.
29. 29. SECRIST H, DEKRUYFF RH, UMETSU DT. IL-4 production by CD4+ T cells from allergic individuals is modulated by antigen concentration and antigen-presenting cell type. J Exp Med 1995;181:1081-1089.
30. 30. CARBADILLO JM, FAITH A, CARBADILLO-PERRIG N, BLASER K. The intensity of T cell receptor engagement determines the cytokine pattern of human allergen-specific T helper cells. Eur J Immunol 1997;27:515-521.
31. 31. O'GARRA A. Cytokines induce the development of functionally heterogeneous T helper subsets. Immunity 1998;8:275-283.
32. 2 synergizes with inflammatory cytokines in the induction of dendritic cells but induces cells with a Th2 cell-promoting function. J Immunol 1998;161:2804-2809.
33. 33. PRESCOTT SL, MACAUBAS C, SMALLACOMBE T, HOLT BJ, SLY PD, HOLT PG. Development of allergen-specific T cell memory in atopic and normal children. Lancet 1999;353:196-200.
34. 34. WILSON CB, WESTALL J, JOHNSTON L, et al. Decreased production of interferon-gamma by human neonatal cells. Intrinsic and extrinsic defects. J Clin Invest 1986;77:860-867.
35. 35. FRENKEL L, BRYSON YJ. Ontogeny of phytohemagglutinin-induced gamma inlerferon by leukocytes of healthy infants and children: evidence for decreased production in infants younger than 2 months of age. Clin Lab Obs 1987;11:97-100.
36. 36. LEWIS DB, YU CC, MEYER J, et al. Cellular and molecular mechanisms for reduced interleukin 4 and interferon-γ production by neonatal T cells. J Clin Invest 1991;87:194-202.
37. 37. TANG MLK, KEMP AS, THORBURN J, HILL DJ. Reduced interferon-γ secretion in neonates and subsequent atopy. Lancet 1994;344:983-985.
38. 38. KONDO N, KOBOYASHI Y, SHINODA S, et al. Cord blood lymphocyte responses to food antigens for the prediction of allergic disorders. Arch Dis Child 1992;67:1003-1007.
39. 39. KONDO N, KOBAYASHI Y, SHINODA S, et al. Reduced Interferon gamma production by antigen-stimulated cord blood mononuclear cells is a risk factor of allergic disorders - 6-year follow-up study. Clin Exp Allergy 1998;28:1340-1344.
40. 40. JUJO K, RENZ, H, ABE J, GELFAND EW, LEUNG DY. Decreased interferon gamma and increased interleukin-4 production in atopic dermatitis promotes IgE synthesis. J Allergy Clin Immunol 1992;90:323-331.
41. 41. JUNG T, LACK G, SCHAUER U, et al. Decreased frequency of interferon-γ and interleukin-2-producing cells in patients with atopic diseases measured at the single cell level. J Allergy Clin Immunol 1995;96:515-527.
42. 42. WILLIAMS TJ, JONES CA, WARNER JO, WARNER JA. Interleukin-13 production during pregnancy and at birth and subsequent development of atopic symptoms 1999 (in press).
43. 43. RICHARDSON VF, LARCHER VF, PRICE JF. Yeast opsonisation in newborn infants and its relationship to parental atopy. Clin Exp Immunol 1982;48:411-416.
44. 44. VAN ASPEREN PP, GLEESON M, KEMP AS, et al. The relationship between atopy and salivary IgA deficiency in infancy. Clin Exp Immunol 1985;62:753-757.
45. 45. HOLT PG, CLOUGH JB, HOLT BJ, et al. Genetic risk for atopy is associated with delayed postnatal maturation of T-cell competence. Clin Exp Allergy 1992;22:1093-1099.
46. 46. PALFI M, SELBING A. Placental transport of maternal immunoglobulin G. Am J Reprod Immunol 1998;39:24-26.
47. 47. SIMISTER NE, STORY CM, CHEN HL, HUNT JS. An IgG-transporting Fc receptor expressed in the syncytiotrophoblast of human placenta. Eur J Immunol 1996;26:1527-1531.
48. 48. SIMISTER NE, STORY CM. Human placental Fc receptors and the transmission of antibodies from mother to fetus. J Reprod Immunol 1997;37:1-23.
49. 49. MALEK A, SAGER R, KUHN P, NICOLAIDES KH, SCHNEIDFR H. Evolution of maternofetal transport during human pregnancy. Am J Reprod Immunol 1996;36:248-255.
50. 50. FUKAMATSU Y, TOMITA K, FUKUTA T. Further evidence of prolactin production from human decidua and its transport across fetal membrane. Gynecol Obstet Invest 1984;17:309-316.
51. 51. JONES CA, WARNER JA, WARNER JO. Fetal swallowing of IgE. Lancet 1998;351:1859.
52. 52. ISRAEL EJ, TAYLOR S, WU Z, et al. Expression of the neonatal Fc receptor, FcRn, on human intestinal epithelial cells. Immunology 1997;92:69-74.
53. 53. SPENCER J, MACDONALD TT, FINN T, ISAACSON PG. Development of Peyer's patches in the human fetal terminal ileum. Clin Exp Immunol 1986;64:536-543.
54. 54. SPENCER J, DILLON SB, ISAACSON PG, MACDONALD TT. T cell subclasses in fetal human ileum. Clin Exp Immunol 1986;65:553-558.
55. 55. BUDDINGTON RK. Nutrition and ontogenetic development of the intestine. Can J Physiol Pharmacol 1994;72:251-259.
56. 56. GITLIN D, KUMATE J, MORALES C, NORIEGA L, AREVALO N. The turnover of amniotic fluid protein in the human conceptus. Am J Obstet Gynecol 1972;113:632-645.
57. 57. GODFREY KM, BARKER DJP, OSMOND C. Disproportionate fetal growth and raised IgE concentration in adult life. Clin Exp Allergy 1994;24:641-648.
58. 58. GREGORY A, DOULL I, PEARCE N, et al. The relationship between anthropometric measurements at birth: asthma and atopy in childhood. Clin Exp Allergy 1999;29:330-333.
59. 59. ORYSZCZYN MP, ANNESI-MAESANO I, CAMPAGNA D, SAHUQUILLO J, HUEL G, KAUFFMAN F. Head circumference at birth and maternal factors related to cord blood total IgE. Clin Exp Allergy 1999;29:334-341.
60. 60. NOVATO-SILVA E, GAZZINELLI G, COLLEY DG. Immune responses during human schistosomiasis mansoni. XVIII. Immunologic status of pregnant women and their neonates. Scand J Immunol 1992;35:429-437.
61. 61. FIEVET N, RINGWALD P, BICKII J, et al. Malaria cellular immune responses in neonates from Cameroon. Parasite Immunol 1996;18:483-490.
62. 62. YU M, FREDRIKSON S, LINK J, LINK H. High numbers of autoantigen-reactive mononuclear cells expressing interferon-gamma, IL-4 and transforming growth factor-beta are present in cord blood. Clin Exp Immunol 1995;101:190-196.
63. 63. JONES AC, MILES EA, WARNER JO, COLWELL BM, BRYANT TN, WARNER JA. Fetal peripheral blood mononuclear cell proliferative responses to mitogenic and allergenic stimuli during gestation. Pediatr Allergy Immunol 1996;7:109-116.
64. 64. BYRNE JA, STANKOVIC AK, COOPER MD. A novel subpopulation of primed T cells in the human fetus. J Immunol 1993;152:3098-3106.
65. 65. DURANDY A, DE SAINT BASILE G, LISOWSKA-GROSPIERRE B, et al. Undetectable CD40 ligand expression on T cells and low B cell responses to CD40 binding agonists in human newborns. J Immunol 1994;154:1560-1568.
66. 66. STROBEL S, MOWAT AM. Immune responses to dietary antigens: oral tolerance. Immunol Today 1998;19:173-181.
67. 67. WIERENGA EA, SNOEK M, DE GROOT C, et al. Evidence for compartmentalisation of functional subsets of CD4+ lymphocytes in atopic patients. J Immunol 1990;144:4651-1656.
68. 68. GARDNER SG, BINGLEY PJ, SAWTELL PA, et al. Rising incidence of insulin dependent diabetes in children under 5 years in the Oxford region: time trend analysis. BMJ 1997;315:713-717.
69. 69. SEPP E, JULGE V, VASAR M, NAABER P, BJÖRKSTÉN B, MIKELSAAR M. Intestinal microflora of Estonian and Swedish infants. Acta Paediatr 1997;86:956-961.
70. 70. BJÖRKSTÉN B, NAABER P, SEPP E, MIKELSAAR M. The intestinal microflora in allergic Estonian and Swedish 2-year-old children. Clin Exp Allergy 1999;29:342-346.
71. 71. PRESCOTT SL, SLY PD, HOLT PG. Raised serum IgE associated with reduced responsiveness to DPT vaccination during infancy. Lancet 1998;351:1489.
72. 72. SHIRAKAWA T, ENOMOTO T, SHIMAZU SI, HOPKIN JM. The inverse association between tuberculin responses and atopic disorder. Science 1997;275:77-79.
73. 73. MARTINEZ FD. Maturation of immune responses at the beginning of asthma. J Allergy Clin Immunol 1999;103:355-361.
74. 74. BALDINI M, LOHMAN IC, HALONEN M, ERICKSON RP, HOLT PG, MARTINEZ FD. A polymorphism in the 5′ flanking region of the CD14 gene is associated with circulating soluble CD14 levels and with total serum immunoglobulin E. Am J Respir Cell Mol Biol 1999;20:976-983.
75. 75. WARNER JA, JONES CA, JONES AC, MILES EA, FRANCIS T, WARNER JO. Immune responses during pregnancy and the development of allergic disease. Pediatr Allergy Immunol 1997;8:5-10.
76. 76. JENMALM MC, HOLT PG, BJÖRKSTÉN B. Maternal influence on IgG subclass antibodies to Bet v 1 during the first 18 months of life as detected with a sensitive ELISA. Int Arch Allergy Immunol 1997;114:175-184.
77. 77. JARRETT EEE, HALL E. IgE suppression by maternal IgG. Immunology 1983;48:49-58.
78. εRI) mediates IgE dependent allergen presentation. J Immunol 1995;154:6285-6290.
79. 79. MUDDE GC, BHEEKHA R, BRUIJNZEEL-KOOMEN CAFM. Consequences of IgE/ CD23-mediated antigen presentation in allergy. Immunol Today 1995;16:380-383.
80. 80. VASSELLA CC, ODELRAM H, KJELLMAN M, BORRES MP, VANTO T, BJÖRKSTÉN B. High anti-IgE levels at birth are associated with a reduced allergy prevalence in infants at risk: a prospective study. Clin Exp Allergy 1992;24:771-777.