-
1
-
-
0029913340
-
Insulin receptor substrate 1 binds two novel splice variants of the regulatory subunit of phosphatidylinositol 3-kinase in muscle and brain
-
Antonetti, D. A., Algenstaedt, P. and Kahn, C. R. (1996). Insulin receptor substrate 1 binds two novel splice variants of the regulatory subunit of phosphatidylinositol 3-kinase in muscle and brain. Mol. Cell Biol. 16, 2195-2203.
-
(1996)
Mol. Cell Biol.
, vol.16
, pp. 2195-2203
-
-
Antonetti, D.A.1
Algenstaedt, P.2
Kahn, C.R.3
-
2
-
-
0032007313
-
In vivo functions of actin-binding proteins
-
Ayscough, K. R. (1998). In vivo functions of actin-binding proteins. Curr. Opin. Cell Biol. 10, 102-111.
-
(1998)
Curr. Opin. Cell Biol.
, vol.10
, pp. 102-111
-
-
Ayscough, K.R.1
-
3
-
-
0032537743
-
Lymphocyte signalling: A coordinating role for Vav?
-
Cantrell, D. (1998). Lymphocyte signalling: a coordinating role for Vav? Curr. Biol. 8, R535-538.
-
(1998)
Curr. Biol.
, vol.8
-
-
Cantrell, D.1
-
4
-
-
0027309278
-
Phosphoinositide 3-kinase is activated by phosphopeptides that bind to the SH2 domains of the 85-kDa subunit
-
Carpenter, C. L., Auger, K. R., Chanudhuri, M., Yoakim, M., Schaffhausen, B., Shoelson, S. and Cantley, L. C. (1993). Phosphoinositide 3-kinase is activated by phosphopeptides that bind to the SH2 domains of the 85-kDa subunit. J. Biol. Chem. 268, 9478-9483.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 9478-9483
-
-
Carpenter, C.L.1
Auger, K.R.2
Chanudhuri, M.3
Yoakim, M.4
Schaffhausen, B.5
Shoelson, S.6
Cantley, L.C.7
-
5
-
-
0028308412
-
Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 s6 kinase, DNA synthesis, and glucose transporter translocation
-
Cheatham, B., Vlahos, C. J., Cheatham, L., Wang, L., Blenis, J. and Kahn, C. R. (1994). Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation. Mol. Cell Biol. 14, 4902-4911.
-
(1994)
Mol. Cell Biol.
, vol.14
, pp. 4902-4911
-
-
Cheatham, B.1
Vlahos, C.J.2
Cheatham, L.3
Wang, L.4
Blenis, J.5
Kahn, C.R.6
-
6
-
-
0018607228
-
Rapid induction of morphological changes in human carcinoma cells A-431 by epidermal growth factors
-
Chinkers, M., McKanna, J. A. and Cohen, S. (1979). Rapid induction of morphological changes in human carcinoma cells A-431 by epidermal growth factors. J. Cell Biol. 83, 260-265.
-
(1979)
J. Cell Biol.
, vol.83
, pp. 260-265
-
-
Chinkers, M.1
McKanna, J.A.2
Cohen, S.3
-
7
-
-
0033174034
-
Phosphatidylinositol-3-OH kinases are Rab5 effectors
-
Christoforidis, S., Miaczynska, M., Ashman, K., Wilm, M., Zhao, L., Yip, S., Waterfield, M. D., Backer, J. M. and Zerial, M. (1999). Phosphatidylinositol-3-OH kinases are Rab5 effectors. Nature Cell Biol. 1, 249-252.
-
(1999)
Nature Cell Biol.
, vol.1
, pp. 249-252
-
-
Christoforidis, S.1
Miaczynska, M.2
Ashman, K.3
Wilm, M.4
Zhao, L.5
Yip, S.6
Waterfield, M.D.7
Backer, J.M.8
Zerial, M.9
-
8
-
-
0028589148
-
Platelet-derived growth factor receptor signals
-
Claesson-Welsh, L. (1994). Platelet-derived growth factor receptor signals. J. Biol. Chem. 269, 32023-6.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 32023-32026
-
-
Claesson-Welsh, L.1
-
9
-
-
0028895654
-
Modular binding domains in signal transduction proteins
-
Cohen, G. B., Ren, R. and Baltimore, D. (1995). Modular binding domains in signal transduction proteins. Cell 80, 237-248.
-
(1995)
Cell
, vol.80
, pp. 237-248
-
-
Cohen, G.B.1
Ren, R.2
Baltimore, D.3
-
10
-
-
0032211844
-
Direct targets of phosphoinositide 3-kinase products in membrane traffic and signal transduction
-
Corvera, S. and Czech, M. P. (1998). Direct targets of phosphoinositide 3-kinase products in membrane traffic and signal transduction. Trends Cell Biol. 8, 442-446.
-
(1998)
Trends Cell Biol.
, vol.8
, pp. 442-446
-
-
Corvera, S.1
Czech, M.P.2
-
11
-
-
0032491398
-
A redox-triggered ras-effector interaction. Recruitment of phosphatidylinositol 3′-kinase to ras by redox stress
-
Deora, A. A., Win, T., Vanhaesebroeck, B. and Lander, H. M. (1998). A Redox-triggered Ras-Effector Interaction. Recruitment of phosphatidylinositol 3′-kinase to ras by redox stress. J. Biol. Chem. 273, 29923-29928.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 29923-29928
-
-
Deora, A.A.1
Win, T.2
Vanhaesebroeck, B.3
Lander, H.M.4
-
12
-
-
0026652899
-
Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways
-
Fantl, W. J., Escobedo, J. A., Martin, G. A., Turck, C. W., del Rosario, M., McCormick, F. and Williams, L. T. (1992). Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways. Cell 69, 413-423.
-
(1992)
Cell
, vol.69
, pp. 413-423
-
-
Fantl, W.J.1
Escobedo, J.A.2
Martin, G.A.3
Turck, C.W.4
Del Rosario, M.5
McCormick, F.6
Williams, L.T.7
-
13
-
-
0031022582
-
Differential effects of constitutively active phosphatidylinositol 3-kinase on glucose transport, glycogen synthase activity, and DNA synthesis in 3T3-L1 adipocytes
-
Frevert, E. U. and Kahn, B. B. (1997). Differential effects of constitutively active phosphatidylinositol 3-kinase on glucose transport, glycogen synthase activity, and DNA synthesis in 3T3-L1 adipocytes. Mol. Cell Biol. 17, 190-198.
-
(1997)
Mol. Cell Biol.
, vol.17
, pp. 190-198
-
-
Frevert, E.U.1
Kahn, B.B.2
-
14
-
-
0028095620
-
Structure, regulation and function of phosphoinositide 3-kinases
-
Fry, M. J. (1994). Structure, regulation and function of phosphoinositide 3-kinases. Biochim. Biophys. Acta 1226, 237-268.
-
(1994)
Biochim. Biophys. Acta
, vol.1226
, pp. 237-268
-
-
Fry, M.J.1
-
15
-
-
0025308055
-
The actin-binding protein prufilin binds to PIP2 and inhibits its hydrolysis by phospholipase C
-
Goldschmidt-Clermont, P. J., Machesky, L. M., Baldassare, J. J. and Pollard, T. D. (1990). The actin-binding protein prufilin binds to PIP2 and inhibits its hydrolysis by phospholipase C. Science 247, 1575-1578.
-
(1990)
Science
, vol.247
, pp. 1575-1578
-
-
Goldschmidt-Clermont, P.J.1
Machesky, L.M.2
Baldassare, J.J.3
Pollard, T.D.4
-
16
-
-
0025760751
-
Regulation of phospholipase C-gamma 1 by profilin and tyrosine phosphorylation
-
Goldschmidt-Clermont, P. J., Kim, J. W., Machesky, L. M., Rhee, S. G. and Pollard, T. D. (1991). Regulation of phospholipase C-gamma 1 by profilin and tyrosine phosphorylation. Science 251, 1231-1233.
-
(1991)
Science
, vol.251
, pp. 1231-1233
-
-
Goldschmidt-Clermont, P.J.1
Kim, J.W.2
Machesky, L.M.3
Rhee, S.G.4
Pollard, T.D.5
-
17
-
-
0028951464
-
Integrin-dependent translocation of phosphoinositide 3-kinase to the cytoskeleton of thrombin-activated platelets involves specific interactions of p85α with actin filaments and focal adhesion kinase
-
Guinebault, C., Payrastre, B., Racaud-Sultan, C., Mazarguil, H., Breton, M., Mauco, G., Plantavid, M. and Chap, H. (1995). Integrin-dependent translocation of phosphoinositide 3-kinase to the cytoskeleton of thrombin-activated platelets involves specific interactions of p85α with actin filaments and focal adhesion kinase. J. Cell Biol. 129, 831-842.
-
(1995)
J. Cell Biol.
, vol.129
, pp. 831-842
-
-
Guinebault, C.1
Payrastre, B.2
Racaud-Sultan, C.3
Mazarguil, H.4
Breton, M.5
Mauco, G.6
Plantavid, M.7
Chap, H.8
-
18
-
-
0029117595
-
Thrombin receptor ligation and activated Rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets
-
Hartwig, J. H., Bokoch, G. M., Carpenter, C. L., Janmey, P. A., Taylor, L. A., Toker, A. and Stossel, T. P. (1995). Thrombin receptor ligation and activated Rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets. Cell 82, 643-653.
-
(1995)
Cell
, vol.82
, pp. 643-653
-
-
Hartwig, J.H.1
Bokoch, G.M.2
Carpenter, C.L.3
Janmey, P.A.4
Taylor, L.A.5
Toker, A.6
Stossel, T.P.7
-
19
-
-
0032547385
-
Signal transduction via platelet-derived growth factor receptors
-
Heldin, C. H., Östman, A. and Rönnstrand, L. (1998). Signal transduction via platelet-derived growth factor receptors. Biochim. Biophys. Acta 1378, F79-113.
-
(1998)
Biochim. Biophys. Acta
, vol.1378
-
-
Heldin, C.H.1
Östman, A.2
Rönnstrand, L.3
-
20
-
-
0026720350
-
Phosphatidylinositol 3-kinase: Structure and expression of the 110 kd catalytic subunit
-
Hiles, I. D., Otsu, M., Volinia, S., Fry, M. J., Gout, I., Dhand, R., Panayotou, G., Ruiz-Larrea, F., Thompson, A., Totty, N. F., Hsuan, J. J., Courtneidge, S. A., Parker, P. J. and Waterfield, M. D. (1992). Phosphatidylinositol 3-kinase: structure and expression of the 110 kd catalytic subunit. Cell 70, 419-429.
-
(1992)
Cell
, vol.70
, pp. 419-429
-
-
Hiles, I.D.1
Otsu, M.2
Volinia, S.3
Fry, M.J.4
Gout, I.5
Dhand, R.6
Panayotou, G.7
Ruiz-Larrea, F.8
Thompson, A.9
Totty, N.F.10
Hsuan, J.J.11
Courtneidge, S.A.12
Parker, P.J.13
Waterfield, M.D.14
-
21
-
-
0019305440
-
Visualization of the peripheral weave of microfilaments in glia cells
-
Höglund, A. S., Karlsson, R., Arro, E., Fredriksson, B. A. and Lindberg, U. (1980). Visualization of the peripheral weave of microfilaments in glia cells. J. Muscle Res. Cell Motil. 1, 127-146.
-
(1980)
J. Muscle Res. Cell Motil.
, vol.1
, pp. 127-146
-
-
Höglund, A.S.1
Karlsson, R.2
Arro, E.3
Fredriksson, B.A.4
Lindberg, U.5
-
22
-
-
0031214960
-
Involvement of phosphatidylinositide 3′-kinase and rac in platelet-derived growth factor-induced actin reorganization and chemotaxis
-
Hooshmand-Rad, R., Claesson-Welsh, L., Wennström, S., Yokote, K., Siegbahn, A. and Heldin, C. H. (1997). Involvement of phosphatidylinositide 3′-kinase and Rac in platelet-derived growth factor-induced actin reorganization and chemotaxis. Exp. Cell Res. 234, 434-441.
-
(1997)
Exp. Cell Res.
, vol.234
, pp. 434-441
-
-
Hooshmand-Rad, R.1
Claesson-Welsh, L.2
Wennström, S.3
Yokote, K.4
Siegbahn, A.5
Heldin, C.H.6
-
23
-
-
0027361002
-
Cloning of a novel, ubiquitously expressed human phosphatidylinositol 3-kinase and identification of its binding site on p85
-
Hu, P., Mondino, A., Skolnik, E. Y. and Schlessinger, J. (1993). Cloning of a novel, ubiquitously expressed human phosphatidylinositol 3-kinase and identification of its binding site on p85. Mol. Cell Biol. 13, 7677-7688.
-
(1993)
Mol. Cell Biol.
, vol.13
, pp. 7677-7688
-
-
Hu, P.1
Mondino, A.2
Skolnik, E.Y.3
Schlessinger, J.4
-
24
-
-
0031473726
-
Phosphorylation of cb1 after stimulation of Nb2 cells with prolactin and its association with phosphatidylinositol 3-kinase
-
Hunter, S., Koch, B. L. and Anderson, S. M. (1997). Phosphorylation of cb1 after stimulation of Nb2 cells with prolactin and its association with phosphatidylinositol 3-kinase. Mol. Endocrinol. 11, 1213-1222.
-
(1997)
Mol. Endocrinol.
, vol.11
, pp. 1213-1222
-
-
Hunter, S.1
Koch, B.L.2
Anderson, S.M.3
-
25
-
-
0030615068
-
p85α gene generates three isoforms of regulatory subunit for phosphatidylinositol 3-kinase (PI 3-kinase). P50α, p55α, and p85α, with different PI 3-kinase activity elevating responses to insulin
-
Inukai, K., Funaki, M., Ogihara, T., Katagiri, H., Kanda, A., Anai, M., Fukushima, Y., Hosaka, T., Suzuki, M., Shin, B. C., Takata, K., Yazaki, Y., Kikuchi, M., Oka, Y. and Asano, T. (1997). p85α gene generates three isoforms of regulatory subunit for phosphatidylinositol 3-kinase (PI 3-Kinase). p50α, p55α, and p85α, with different PI 3-kinase activity elevating responses to insulin. J. Biol. Chem. 272, 7873-7882.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 7873-7882
-
-
Inukai, K.1
Funaki, M.2
Ogihara, T.3
Katagiri, H.4
Kanda, A.5
Anai, M.F.Y.6
Hosaka, T.7
Suzuki, M.8
Shin, B.C.9
Takata, K.10
Yazaki, Y.11
Kikuchi, M.12
Oka, Y.13
Asano, T.14
-
26
-
-
0028143039
-
Microinjection of the SH2 domain of the 85-kilodalton subunit of phosphatidylinositol 3-kinase inhibits insulin-induced DNA synthesis and c-fos expression
-
Jhun, B. H., Rose, D. W., Seely, B. L., Rameh, L., Cantley, L., Saltiel, A. R. and Olefsky, J. M. (1994). Microinjection of the SH2 domain of the 85-kilodalton subunit of phosphatidylinositol 3-kinase inhibits insulin-induced DNA synthesis and c-fos expression. Mol. Cell Biol. 14, 7466-7475.
-
(1994)
Mol. Cell Biol.
, vol.14
, pp. 7466-7475
-
-
Jhun, B.H.1
Rose, D.W.2
Seely, B.L.3
Rameh, L.4
Cantley, L.5
Saltiel, A.R.6
Olefsky, J.M.7
-
27
-
-
0031917412
-
Insulin-like growth factors require phosphatidylinositol 3-kinase to signal myogenesis: Dominant negative p85 expression blocks differentiation of L6E9 muscle cells. Mol
-
Kaliman, P., Canicio, J., Shepherd, P. R., Beeton, C. A., Testar, X., Palacin, M. and Zorzano, A. (1998). Insulin-like growth factors require phosphatidylinositol 3-kinase to signal myogenesis: dominant negative p85 expression blocks differentiation of L6E9 muscle cells. Mol. Endocrinol. 12, 66-77.
-
(1998)
Endocrinol.
, vol.12
, pp. 66-77
-
-
Kaliman, P.1
Canicio, J.2
Shepherd, P.R.3
Beeton, C.A.4
Testar, X.5
Palacin, M.6
Zorzano, A.7
-
28
-
-
0026664293
-
GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit
-
Kazlauskas, A., Kashishian, A., Cooper, J. A. and Valius, M. (1992). GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit. Mol. Cell Biol. 12, 2534-2544.
-
(1992)
Mol. Cell Biol.
, vol.12
, pp. 2534-2544
-
-
Kazlauskas, A.1
Kashishian, A.2
Cooper, J.A.3
Valius, M.4
-
29
-
-
2642683510
-
Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse
-
Kerouz, N. J., Horsch, D., Pons, S. and Kahn, C. R. (1997). Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse. J. Clin. Invest. 100, 3164-3172.
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 3164-3172
-
-
Kerouz, N.J.1
Horsch, D.2
Pons, S.3
Kahn, C.R.4
-
30
-
-
0028198330
-
The interaction of small domains between the subunits of phosphatidylinositol 3-kinase determines enzyme activity
-
Klippel, A., Escobedo, J. A., Hirano, M. and Williams, L. T. (1994). The interaction of small domains between the subunits of phosphatidylinositol 3-kinase determines enzyme activity. Mol. Cell Biol. 14, 2675-2685.
-
(1994)
Mol. Cell Biol.
, vol.14
, pp. 2675-2685
-
-
Klippel, A.1
Escobedo, J.A.2
Hirano, M.3
Williams, L.T.4
-
31
-
-
0028264058
-
Involvement of phosphoinositide 3-kinase in insulin-or IGF-induced membrane ruffling
-
Kotani, K., Yonezawa, K., Hara, K., Ueda, H., Kitamura, Y., Sakaue, H., Ando, A., Chavanieu, A., Calas, B., Grigorescu, F., Nishiyama, M., Waterfield, M. D. and Kasuga, M. (1994). Involvement of phosphoinositide 3-kinase in insulin-or IGF-induced membrane ruffling. EMBO J. 13, 2313-2321.
-
(1994)
EMBO J.
, vol.13
, pp. 2313-2321
-
-
Kotani, K.1
Yonezawa, K.2
Hara, K.3
Ueda, H.4
Kitamura, Y.5
Sakaue, H.6
Ando, A.7
Chavanieu, A.8
Calas, B.9
Grigorescu, F.10
Nishiyama, M.11
Waterfield, M.D.12
Kasuga, M.13
-
32
-
-
0028055272
-
Regulation of chemotaxis by the platelet-derived growth factor receptor-beta
-
Kundra, V., Escobedo, J. A., Kazlauskas, A., Kim, H. K., Rhee, S. G., Williams, L. T. and Zetter, B. R. (1994). Regulation of chemotaxis by the platelet-derived growth factor receptor-beta. Nature 367, 474-476.
-
(1994)
Nature
, vol.367
, pp. 474-476
-
-
Kundra, V.1
Escobedo, J.A.2
Kazlauskas, A.3
Kim, H.K.4
Rhee, S.G.5
Williams, L.T.6
Zetter, B.R.7
-
33
-
-
0030869757
-
Heterodimeric phosphoinositide 3-kinase consisting of p85 and p110β is synergistically activated by the βγ subunits of G proteins and phosphotyrosyl peptide
-
Kurosu, H., Maehama, T., Okada, T., Yamamoto, T., Hoshino, S., Fukui, Y., Ui, M., Hazeki, O. and Katada, T. (1997). Heterodimeric phosphoinositide 3-kinase consisting of p85 and p110β is synergistically activated by the βγ subunits of G proteins and phosphotyrosyl peptide. J. Biol. Chem. 272, 24252-24256.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 24252-24256
-
-
Kurosu, H.1
Maehama, T.2
Okada, T.3
Yamamoto, T.4
Hoshino, S.5
Fukui, Y.6
Ui, M.7
Hazeki, O.8
Katada, T.9
-
34
-
-
0021919105
-
Specific interaction between phosphatidylinositol 4, 5-bisphosphate and profilactin
-
Lassing, I. and Lindberg, U. (1985). Specific interaction between phosphatidylinositol 4, 5-bisphosphate and profilactin. Nature 314, 472-474.
-
(1985)
Nature
, vol.314
, pp. 472-474
-
-
Lassing, I.1
Lindberg, U.2
-
35
-
-
0027214258
-
The v-Src SH3 domain binds phosphatidylinositol 3′-kinase
-
Liu, X., Marengere, L. E., Koch, C. A. and Pawson, T. (1993). The v-Src SH3 domain binds phosphatidylinositol 3′-kinase. Mol. Cell Biol. 13, 5225-5232.
-
(1993)
Mol. Cell Biol.
, vol.13
, pp. 5225-5232
-
-
Liu, X.1
Marengere, L.E.2
Koch, C.A.3
Pawson, T.4
-
36
-
-
0029946425
-
Lipid products of phosphoinositide 3-kinase bind human profilin with high affinity
-
Lu, P. J., Shieh, W. R., Rhee, S. G., Yin, H. L. and Chen, C. S. (1996). Lipid products of phosphoinositide 3-kinase bind human profilin with high affinity. Biochemistry 35, 14027-14034.
-
(1996)
Biochemistry
, vol.35
, pp. 14027-14034
-
-
Lu, P.J.1
Shieh, W.R.2
Rhee, S.G.3
Yin, H.L.4
Chen, C.S.5
-
37
-
-
0031035636
-
Specific activation of p85-p110 phosphatidylinositol 3′-kinase stimulates DNA synthesis by ras- and p70 s6 kinase-dependent pathways
-
McIlroy, J., Chen, D., Wjasow, C., Michaeli, T. and Backer, J. M. (1997). Specific activation of p85-p110 phosphatidylinositol 3′-kinase stimulates DNA synthesis by ras- and p70 S6 kinase-dependent pathways. Mol. Cell Biol. 17, 248-255.
-
(1997)
Mol. Cell Biol.
, vol.17
, pp. 248-255
-
-
McIlroy, J.1
Chen, D.2
Wjasow, C.3
Michaeli, T.4
Backer, J.M.5
-
38
-
-
0021034443
-
The effect of platelet-derived growth factor on morphology and motility of human glial cells
-
Mellström, K., Höglund, A. S., Nistér, M., Heldin, C. H., Westermark, B. and Lindberg, U. (1983). the effect of platelet-derived growth factor on morphology and motility of human glial cells. J. Muscle Res. Cell Motil. 4, 589-609.
-
(1983)
J. Muscle Res. Cell Motil.
, vol.4
, pp. 589-609
-
-
Mellström, K.1
Höglund, A.S.2
Nistér, M.3
Heldin, C.H.4
Westermark, B.5
Lindberg, U.6
-
39
-
-
0029811141
-
Compartment-specific regulation of phosphoinositide 3-kinase by platelet-derived growth factor and insulin in 3T3-L1 adipocytes
-
Nave, B. T., Haigh, R. J., Hayward, A. C., Siddle, K. and Shepherd, P. R. (1996). Compartment-specific regulation of phosphoinositide 3-kinase by platelet-derived growth factor and insulin in 3T3-L1 adipocytes. Biochem. J. 318, 55-60.
-
(1996)
Biochem. J.
, vol.318
, pp. 55-60
-
-
Nave, B.T.1
Haigh, R.J.2
Hayward, A.C.3
Siddle, K.4
Shepherd, P.R.5
-
40
-
-
0028837170
-
Activation of the small GTP-binding proteins rho and rac by growth factor receptors
-
Nobes, C. D., Hawkins, P., Stephens, L. and Hall, A. (1995). Activation of the small GTP-binding proteins rho and rac by growth factor receptors. J. Cell Sci. 108, 225-233.
-
(1995)
J. Cell Sci.
, vol.108
, pp. 225-233
-
-
Nobes, C.D.1
Hawkins, P.2
Stephens, L.3
Hall, A.4
-
41
-
-
0028198388
-
Activation of phosphatidylinositol-3′ kinase by Src-family kinase SH3 binding to the p85 subunit
-
Pleiman, C. M., Hertz, W. M. and Cambier, J. C. (1994). Activation of phosphatidylinositol-3′ kinase by Src-family kinase SH3 binding to the p85 subunit. Science 263, 1609-1612.
-
(1994)
Science
, vol.263
, pp. 1609-1612
-
-
Pleiman, C.M.1
Hertz, W.M.2
Cambier, J.C.3
-
42
-
-
0028584245
-
The phosphatidylinositol 3-kinase α is required for DNA synthesis induced by some, but not all, growth factors
-
Roche, S., Koegl, M. and Courtneidge, S. A. (1994). The phosphatidylinositol 3-kinase α is required for DNA synthesis induced by some, but not all, growth factors. Proc. Nat. Acad. Sci. USA 91, 9185-9189.
-
(1994)
Proc. Nat. Acad. Sci. USA
, vol.91
, pp. 9185-9189
-
-
Roche, S.1
Koegl, M.2
Courtneidge, S.A.3
-
43
-
-
0031725052
-
A function for phosphatidylinositol 3-kinase beta (p85α-p110β) in fibroblasts during mitogenesis: Requirement for insulin- and lysophosphatidic acid-mediated signal transduction
-
Roche, S., Downward, J., Raynal, P. and Courtneidge, S. A. (1998). A function for phosphatidylinositol 3-kinase beta (p85α-p110β) in fibroblasts during mitogenesis: requirement for insulin- and lysophosphatidic acid-mediated signal transduction. Mol. Cell Biol. 18, 7119-7129.
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 7119-7129
-
-
Roche, S.1
Downward, J.2
Raynal, P.3
Courtneidge, S.A.4
-
44
-
-
0030854777
-
Differential regulation of phosphoinositide 3-kinase adapter subunit variants by insulin in human skeletal muscle
-
Shepherd, P. R., Nave, B. T., Rincon, J., Nolte, L. A., Bevan, A. P., Siddle, K., Zierath, J. R. and Wallberg-Henriksson, H. (1997). Differential regulation of phosphoinositide 3-kinase adapter subunit variants by insulin in human skeletal muscle. J. Biol. Chem. 272, 19000-19007.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 19000-19007
-
-
Shepherd, P.R.1
Nave, B.T.2
Rincon, J.3
Nolte, L.A.4
Bevan, A.P.5
Siddle, K.6
Zierath, J.R.7
Wallberg-Henriksson, H.8
-
45
-
-
0028050414
-
Phosphatidylinositol 3-kinase binds to α-actinin through the p85 subunit
-
Shibasaki, F., Fukami, K., Fukui, Y. and Takenawa, T. (1994). Phosphatidylinositol 3-kinase binds to α-actinin through the p85 subunit. Biochem. J. 302, 551-557.
-
(1994)
Biochem. J.
, vol.302
, pp. 551-557
-
-
Shibasaki, F.1
Fukami, K.2
Fukui, Y.3
Takenawa, T.4
-
46
-
-
0032517624
-
Distinct roles for the p110α and hVPS34 phosphatidylinositol 3′-kinases in vesicular trafficking, regulation of the actin cytoskeleton, and mitogenesis. J
-
Siddhanta, U., McIlroy, J., Shah, A., Zhang, Y. and Backer, J. M. (1998). Distinct roles for the p110α and hVPS34 phosphatidylinositol 3′-kinases in vesicular trafficking, regulation of the actin cytoskeleton, and mitogenesis. J. Cell Biol. 143, 1647-1659.
-
(1998)
Cell Biol.
, vol.143
, pp. 1647-1659
-
-
Siddhanta, U.1
McIlroy, J.2
Shah, A.3
Zhang, Y.4
Backer, J.M.5
-
47
-
-
0030475263
-
Profilin and gelsolin stimulate phosphatidylinositol 3-kinase activity
-
Singh, S. S., Chauhan, A., Murakami, N. and Chauhan, V. P. (1996). Profilin and gelsolin stimulate phosphatidylinositol 3-kinase activity. Biochemistry 35, 16544-16549.
-
(1996)
Biochemistry
, vol.35
, pp. 16544-16549
-
-
Singh, S.S.1
Chauhan, A.2
Murakami, N.3
Chauhan, V.P.4
-
48
-
-
0019840118
-
Organization of actin in the leading edge of cultured cells: Influence of osmium tetroxide and dehydration on the ultrastructure of actin meshworks
-
Small, J. V. (1981). Organization of actin in the leading edge of cultured cells: influence of osmium tetroxide and dehydration on the ultrastructure of actin meshworks. J. Cell Biol. 91, 695-705.
-
(1981)
J. Cell Biol.
, vol.91
, pp. 695-705
-
-
Small, J.V.1
-
49
-
-
0033004571
-
Functional design in the actin cytoskeleton
-
Small, J. V., Rottner, K. and Kaverina, I. (1999). Functional design in the actin cytoskeleton. Curr. Opin. Cell Biol. 11, 54-60.
-
(1999)
Curr. Opin. Cell Biol.
, vol.11
, pp. 54-60
-
-
Small, J.V.1
Rottner, K.2
Kaverina, I.3
-
50
-
-
0027366440
-
Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphosphate: A new intracellular signalling system?
-
Stephens, L. R., Jackson, T. R. and Hawkins, P. T. (1993). Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphosphate: a new intracellular signalling system? Biochim. Biophys. Acta 1179, 27-75.
-
(1993)
Biochim. Biophys. Acta
, vol.1179
, pp. 27-75
-
-
Stephens, L.R.1
Jackson, T.R.2
Hawkins, P.T.3
-
51
-
-
0028334738
-
A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein βγ subunits
-
Stephens, L., Smrcka, A., Cooke, F. T., Jackson, T. R., Sternweis, P. C. and Hawkins, P. T. (1994). A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein βγ subunits. Cell 77, 83-93.
-
(1994)
Cell
, vol.77
, pp. 83-93
-
-
Stephens, L.1
Smrcka, A.2
Cooke, F.T.3
Jackson, T.R.4
Sternweis, P.C.5
Hawkins, P.T.6
-
52
-
-
0029090212
-
Cloning and characterization of a g protein-activated human phosphoinositide-3 kinase
-
Stoyanov, B., Volinia, S., Hanck, T., Rubio, I., Loubtchenkov, M., Malek, D., Stoyanova, S., Vanhaesebroeck, B., Dhand, R., Nurnberg, B., Gierschik, P., Seedorf, K., Hsuan, J. J., Waterfield, M. D. and Wetzker, R. (1995). Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase. Science 269, 690-693.
-
(1995)
Science
, vol.269
, pp. 690-693
-
-
Stoyanov, B.1
Volinia, S.2
Hanck, T.3
Rubio, I.4
Loubtchenkov, M.5
Malek, D.6
Stoyanova, S.7
Vanhaesebroeck, B.8
Dhand, R.9
Nurnberg, B.10
Gierschik, P.11
Seedorf, K.12
Hsuan, J.J.13
Waterfield, M.D.14
Wetzker, R.15
-
53
-
-
0029080520
-
Wortmannin, a specific phosphatidylinositol 3-kinase inhibitor, inhibits adipocytic differentiation of 3T3-L1 cells
-
Tomiyama, K., Nakata, H., Sasa, H., Arimura, S., Nishio, E. and Watanabe, Y. (1995). Wortmannin, a specific phosphatidylinositol 3-kinase inhibitor, inhibits adipocytic differentiation of 3T3-L1 cells. Biochem. Biophys Res. Commun. 212, 263-269.
-
(1995)
Biochem. Biophys Res. Commun.
, vol.212
, pp. 263-269
-
-
Tomiyama, K.1
Nakata, H.2
Sasa, H.3
Arimura, S.4
Nishio, E.5
Watanabe, Y.6
-
54
-
-
0030805703
-
Phosphoinositide 3-kinases: A conserved family of signal transducers
-
Vanhaesebroeck, B., Leevers, S. J., Panayotou, G. and Waterfield, M. D. (1997a). Phosphoinositide 3-kinases: a conserved family of signal transducers. Trends Biochem. Sci. 22, 267-272.
-
(1997)
Trends Biochem. Sci.
, vol.22
, pp. 267-272
-
-
Vanhaesebroeck, B.1
Leevers, S.J.2
Panayotou, G.3
Waterfield, M.D.4
-
55
-
-
0030611198
-
P110δ, a novel phosphoinositide 3-kinase in leukocytes
-
Vanhaesebroeck, B., Welham, M. J., Kotani, K., Stein, R., Warne, P. H., Zvelebil, M. J., Higashi, K., Volinia, S., Downward, J. and Waterfield, M. D. (1997b). P110δ, a novel phosphoinositide 3-kinase in leukocytes. Proc. Nat. Acad. Sci. USA 94, 4330-4335.
-
(1997)
Proc. Nat. Acad. Sci. USA
, vol.94
, pp. 4330-4335
-
-
Vanhaesebroeck, B.1
Welham, M.J.2
Kotani, K.3
Stein, R.4
Warne, P.H.5
Zvelebil, M.J.6
Higashi, K.7
Volinia, S.8
Downward, J.9
Waterfield, M.D.10
-
56
-
-
0033128166
-
Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages
-
Vanhaesebroeck, B., Jones, G. E., Allen, W. E., Zicha, D., Hooshmand-Rad, R., Sawyer, C., Wells, C., Waterfield, M. D. and Ridley, A. J. (1999a). Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages. Nature Cell Biol. 1, 69-71.
-
(1999)
Nature Cell Biol.
, vol.1
, pp. 69-71
-
-
Vanhaesebroeck, B.1
Jones, G.E.2
Allen, W.E.3
Zicha, D.4
Hooshmand-Rad, R.5
Sawyer, C.6
Wells, C.7
Waterfield, M.D.8
Ridley, A.J.9
-
57
-
-
0033104502
-
Autophosphorylation of p110δ phosphoinositide 3-kinase: A new paradigm for the regulation of lipid kinases in vitro and in vivo
-
Vanhaesebroeck, B., Higashi, K., Raven, C., Welham, M., Anderson, S., Brennan, P., Ward, S. G. and Waterfield, M. D. (1999b). Autophosphorylation of p110δ phosphoinositide 3-kinase: a new paradigm for the regulation of lipid kinases in vitro and in vivo. EMBO J. 18, 1292-1302.
-
(1999)
EMBO J.
, vol.18
, pp. 1292-1302
-
-
Vanhaesebroeck, B.1
Higashi, K.2
Raven, C.3
Welham, M.4
Anderson, S.B.P.5
Ward, S.G.6
Waterfield, M.D.7
-
58
-
-
0029046983
-
Direct association of Grb2 with the p85 subunit of phosphatidylinositol 3-kinase
-
Wang, J., Auger, K. R., Jarvis, L., Shi, Y. and Roberts, T. M. (1995). Direct association of Grb2 with the p85 subunit of phosphatidylinositol 3-kinase. J. Biol. Chem. 270, 12774-12780.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 12774-12780
-
-
Wang, J.1
Auger, K.R.2
Jarvis, L.3
Shi, Y.4
Roberts, T.M.5
-
59
-
-
0032080114
-
Actin filaments participate in the relocalization of phosphatidylinositol 3-kinase to glucose transporter-containing compartments and in the stimulation of glucose uptake in 3T3-L1 adipocytes
-
Wang, Q., Bilan, P. J., Tsakiridis, T., Hinek, A. and Klip, A. (1998). Actin filaments participate in the relocalization of phosphatidylinositol 3-kinase to glucose transporter-containing compartments and in the stimulation of glucose uptake in 3T3-L1 adipocytes. Biochem. J. 331, 917-928.
-
(1998)
Biochem. J.
, vol.331
, pp. 917-928
-
-
Wang, Q.1
Bilan, P.J.2
Tsakiridis, T.3
Hinek, A.4
Klip, A.5
-
60
-
-
0028429961
-
Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling
-
Wennström, S., Hawkins, P., Cooke, F., Hara, K., Yonezawa, K., Kasuga, M., Jackson, T., Claesson-Welsh, L. and Stephens, L. (1994a). Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling. Curr. Biol. 4, 385-393.
-
(1994)
Curr. Biol.
, vol.4
, pp. 385-393
-
-
Wennström, S.1
Hawkins, P.2
Cooke, F.3
Hara, K.4
Yonezawa, K.5
Kasuga, M.6
Jackson, T.7
Claesson-Welsh, L.8
Stephens, L.9
-
61
-
-
0028089005
-
Membrane ruffling and chemotaxis transduced by the PDGF β-receptor require the binding site for phosphatidylinositol 3′ kinase
-
Wennström, S., Siegbahn, A., Yokote, K., Arvidsson, A. K., Heldin, C. H., Mori, S. and Claesson-Welsh, L. (1994b). Membrane ruffling and chemotaxis transduced by the PDGF β-receptor require the binding site for phosphatidylinositol 3′ kinase. Oncogene 9, 651-660.
-
(1994)
Oncogene
, vol.9
, pp. 651-660
-
-
Wennström, S.1
Siegbahn, A.2
Yokote, K.3
Arvidsson, A.K.4
Heldin, C.H.5
Mori, S.6
Claesson-Welsh, L.7
-
62
-
-
0028963084
-
Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor
-
Yao, R. and Cooper, G. M. (1995). Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor. Science 267, 2003-2006.
-
(1995)
Science
, vol.267
, pp. 2003-2006
-
-
Yao, R.1
Cooper, G.M.2
-
63
-
-
0030810618
-
Inhibition of phosphatidylinositol 3-kinase by c-Abl in the genotoxic stress response
-
Yuan, Z. M., Utsugisawa, T., Huang, Y., Ishiko, T., Nakada, S., Kharbanda, S., Weichselbaum, R. and Kufe, D. (1997). Inhibition of phosphatidylinositol 3-kinase by c-Abl in the genotoxic stress response. J. Biol. Chem. 272, 23485-23488.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 23485-23488
-
-
Yuan, Z.M.1
Utsugisawa, T.2
Huang, Y.3
Ishiko, T.4
Nakada, S.5
Kharbanda, S.6
Weichselbaum, R.7
Kufe, D.8
|