Phosphorylation of cbl after stimulation of Nb2 cells with prolactin and its association with phosphatidylinositol 3-kinase

Molecular Endocrinology

Volumn 11, Issue 9, 1997, Pages 1213-1222

  Hunter, Seija ^a   Koch, Becky L ^a   Anderson, Steven M ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROLACTIN; PROLACTIN RECEPTOR; PROLINE; PROTEIN; TYROSINE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DENSITOMETRY; ENZYME ACTIVATION; ENZYME SUBUNIT; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT;

EID: 0031473726     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/mend.11.9.9980     Document Type: Article

References (46)

1. Langdon WY, Hartley JW, Klinken SP, Ruscetti SK, Morse HC 1989 v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas. Proc Natl Acad Sci USA 86:1168-1172
2. Blake TJ, Shapiro M, Morse HC, Langdon WY 1991 The sequences of human and mouse c-cbl proto-oncogenes show v-cbl was generated by a large truncation encompassing a proline-rich domain and a leucine zipper-like motif. Oncogene 6:653-657
3. Blake TJ, Heath KG, Langdon WY 1993 The truncation that generated the v-cbl oncogene reveals n ability for nuclear transport, DNA binding and acute transformation. EMBO J 12:2017-2026
4. Hartley D, Meisner H, Corvera S 1995 Specific association of the β isoform of the p85 subunit of phosphatidylinositol-3 kinase with the proto-oncogene c-cbl. J Biol Chem 270:18260-18263
5. Donovan JA, Wange RL, Langdon WY, Samelson LE 1994 The protein product of the c-cbl protooncogene is the 120-kDa tyrosine-phosphorylated protein in Jurkat cells activated via the T cell antigen receptor. J Biol Chem 269:22921-22924
6. Fukazawa T, Reedquist KA, Trub T, Soltoff S, Panchamoorthy G, Druker B, Cantley L, Shoelson SE, Band H 1995 The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with fyn, grb2 and phosphatidylinositol 3-kinase. J Biol Chem 270:19141-19150
7. cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with fyn and syk tyrosine kinases, grb2 and she adapters, and the p85 subunit of phosphatidylinositol 3-kinase. J Biol Chem 271:3187-3194
8. Smit L, van Der Horst G, Borst J 1996 Formation of shc/grb2- and crk adapter complexes containing tyrosine phosphorylated cbl upon stimulation of the B-cell antigen receptor. Oncogene 13:381-389
9. Tanaka S, Neff L, Baron R, Levy JB 1995 Tyrosine phosphorylation and translocation of the c-cbl protein after activation of tyrosine kinase signaling pathways. J Biol Chem 270:14347-14351
10. Marcilla A, Rivero-Lezcano OM, Agarwal A, Robbins KC 1995 Identification of the major tyrosine kinase substrate in signaling complexes formed after engagement of Fc-γ receptors. J Biol Chem 270:9115-9120
11. cbl is a cytosolic adapter protein that associates with phosphoinositide 3-kinase in response to epidermal growth factor in PC12 and other cells. J Biol Chem 271:563-567
12. Galisteo ML, Dikic I, Batzer AG, Langdon WY, Schlessinger J 1995 Tyrosine phosphorylation of the c-cbl protooncogene protein product and association with epidermal growth factor (EGF) receptor upon EGF stimulation. J Biol Chem 270:20242-20245
13. Levkowitz G, Klapper LN, Tzahar E, Freywald A, Sela M, Yarden Y 1996 Coupling of the c-cbl protooncogene product to erbB-1/EGF but not to other erbB proteins. Oncogene 12:1117-1125
14. Fukazawa T, Miyake S, Band V, Band H 1996 Tyrosine phosphorylation of cbl upon epidermal growth factor (EGF) stimulation and its association with EGF receptor and downstream signaling proteins. J Biol Chem 271:14554-14559
15. Wang Y, Yeung Y-G, Langdon WY, Stanley ER 1996 c-cbl is transiently tyrosine-phosphorylated, ubiquitinated, and membrane targeted following CSF-1 stimulation of macrophages. J Biol Chem 271:17-20
16. Odai H, Sasaki K, Iwamatsu A, Hanazono Y, Tanaka T, Mitani K, Yazaki Y, Hirai H 1995 The proto-oncogene product c-cbl becomes tyrosine phosphorylated by stimulation with GM-CSF or epo and constitutively binds to the SH3 domain of GRB2/Ash in human hematopoietic cells. J Biol Chem 270:10800-10805
17. Anderson SM, Burton EA, Koch BL 1997 Phosphorylation of cbl following stimulation with interleukin-3 and its association with grb2, fyn, and phosphatidylinositol 3-kinase. J Biol Chem 272:739-745
18. Ribon V, Hubbell S, Herrera R, Saltiel AR 1996 The product of the cbl oncogene forms stable complexes in vivo with endogenous crk in a tyrosine phosphorylation-dependent manner. Mol Cell Biol 16:45-52
19. BCR/ABL to the phosphatidylinositol-3′ kinase pathway. Oncogene 12:839-846
20. de Jong R, ten Hoeve J, Heisterkamp N, Groffen J 1995 Crkl is Complexed with Tyrosine-Phosphorylated Cbl in Ph-positive Leukemia. J Biol Chem 270:21468-21471
21. Kelly PA, Djiane J, Postel-Vinay M-C, Edery M 1991 The prolactin/growth hormone receptor family. Endocr Rev 12:235-251
22. Boutin J-M, Edery M, Shirota M, Jolicoeur C, Lesueur LA, S, Gould D, Djiane J, Kelly PA 1989 Identification of a cDNA encoding a long form of prolactin receptor in human hepatoma and breast cancer cells. Mol Endocrinol 3:1455-1461
23. Boutin J-M, Jolicoeur C, Okamura H, Gagnon J, Edery M, Shirota M, Banville D, Dusanter-Fourt I, Djiane J, Kelly PA 1988 Cloning and expression of the rat prolactin receptor, a member of the growth hormone/prolactin receptor family. Cell 53:69-77
24. Shirota M, Banville D, Ali S, Jolicoeur C, Boutin J-M, Edery M, Djiane J, Kelly PA 1990 Expression of two forms of prolactin receptor in rat ovary and liver. Mol Endocrinol 4:1136-1143
25. Edery M, Jolicoeur C, Levi-Meyers C, Dusanter-Fourt IP, B, Boutin J-M, Lesueur L, Kelly PA, Djiane J 1989 Identification and sequence analysis of a second form of prolactin receptor by molecular cloning of complementary DNA from rabbit mammary gland. Proc Natl Acad Sci USA 86:2112-2116
26. Rui H, Kirken RA, Farrar WL 1994 Activation of receptor-associated tyrosine kinase JAK2 by prolactin. J Biol Chem 269:5364-5368
27. Lebrun J-J, Ali S, Sofer L, Ullrich A, Kelly PA 1994 Prolactin-induced proliferation of Nb2 cells involves tyrosine phosphorylation of the prolactin receptor and its associated tyrosine kinase JAK2. J Biol Chem 269:14021-14026
28. David M, Petricoin EF, III, Igarashi K-I, Feldman GM, Finbloom DS, Larner AC 1994 Prolactin activates the interferon-regulated p91 transcription factor and the JAK2 kinase by tyrosine phosphorylation. Proc Natl Acad Sci USA 91:7174-7178
29. Gale NW, Kaplan S, Lowenstein EJ, Schlessinger J, BarSagi D 1993 Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras. Nature 363:88-92
30. Egan SE, Giddings BW, Brooks MW, Buday L, Sizeland AM, Weinberg RA 1993 Association of Sos ras exchange protein with grb2 is implicated in tyrosine kinase signal transduction and transformation. Nature 363:45-51
31. Li N, Batzer A, Daly R, Yajnik V, Skolnik E, Chardin P, Bar-Sagi D, Margolis B, Schlessinger J 1993 Guanine-nucleotide-releasing factor hSos1 binds to grb2 and links receptor tyrosine kinases to ras signalling. Nature 363:85-88
32. Chardin P, Camonis JH, Gale NW, Van Aelst L, Schlessinger J, Wigler MH, Bar-Sagi D 1993 Human Sos1: a guanine nucleotide exchange factor for ras that binds to GRB2. Science 260:1338-1343
33. Bunday L, Downward J 1993 Epidermal growth factor regulates p21ras through the formation of a complex of receptor, grb2 adapter protein, and Sos nucleotide exchange factor. Cell 73:611-620
34. fyn mediates binding to phosphatidylinositol 3-kinase in T cells. Proc Natl Acad Sci USA 90:7366-7370
35. Yoakim M, Hou W, Songyang Z, Liu Y, Cantley L, Schaffhausen B 1994 Genetic analysis of a phosphotidylinositol 3-kinase SH2 domain reveals determinants of specificity. Mol Cell Biol 14:5929-5938
36. Songyang Z, Shoelson SE, Chaudhuri M, Gish G, Pawson T, Haser WG, King F, Roberts T, Ratnofsky S, Lechleider RJ, et al. 1993 SH2 domains recognize specific phosphopeptide sequences. Cell 72:767-778
37. Songyang Z, Shoelson SE, McGlade J, Olivier P, Pawson T, Bustelo XR, Barbacid M, Sabe H, Hanafusa H, Yi T, Ren R, Baltimore D, Ratnofsky S, Feldman RA, Cantley LC 1994 Specific motifs recognized by the SH2 domains of csk, 3BP2,fps/fes, GRB-2, HCP, SHC, syk, and vav. Mol Cell Biol 14:2777-2785
38. Ren R, Mayer BJ, Cicchetti P, Baltimore D 1993 Identification of a ten-amino acid proline-rich SH3 binding site. Science 259:1157-1161
39. Andoniou CE, Thein CBF, Langdon WY 1995 Tumor induction by activated abl involves tyrosine phosphorylation if he product of the cbl oncogene. J Biol Chem 270:4515-4523
40. Al-Sakkaf KA, Dobson PRM, Brown BL 1996 Activation of phosphatidylinositol 3-kinase by prolactin in Nb2 cells. Biochem Biophys Res Commun 221:779-784
41. Berlanga JJ, Gualillo O, Buteau H, Applanat M, Kelly PA, Edery M 1997 Prolactin activates tyrosyl phosphorylation of insulin receptor substrate 1 and phosphatidylinositol-3-OH kinase. J Biol Chem 272:2050-2052
42. Pleiman CM, Hertz WM, Cambier JC 1994 Activation of phosphatidylinositol-3′ kinase by src-family kinase SH3 binding to the p85 subunit. Science 263:1609-1612
43. Anderson SM, Jorgensen B 1995 Activation of src-related tyrosine kinases by IL-3. J Immunol 155:1660-1670
44. Whitman M, Downs CP, Keeler M, Keller T, Cantley L 1988 Evidence for two distinct phosphatidylinositol kinases in fibroblasts: implication for cellular regulation. Nature 332:644-646
45. src protein. Mol Cell Biol 9:1651-1658
46. Rameh LE, Chen C-S, Cantley L 1995 Phosphatidylinositol (3, 4, 5)P3 interacts with SH2 domains and modulates PI 3-kinase association with tyrosine-phosphorylated proteins. Cell 83:821-830