Transient effects of long-term leptin supplementation in the prevention of diet-induced obesity in mice

Diabetes

Volumn 49, Issue 7, 2000, Pages 1203-1208

  Surwit, Richard S ^a   Edwards, Christopher L ^a   Murthy, Suma ^a   Petro, Ann E ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DIABETIC OBESITY; DISEASE ASSOCIATION; FAT INTAKE; GLUCOSE BLOOD LEVEL; INSULIN BLOOD LEVEL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL;

EID: 0033921914     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.49.7.1203     Document Type: Article

References (38)

1. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman J: Positional cloning of the mouse obese gene and its human homologue. Nature 372:425-432, 1994
2. Tartaglia LA, Dembski M, Weng X, Deng N, Culpepper J, Devos R, Richards GJ, Campfield LA, Clark FT, Deeds J, Muir C, Sanker S, Moriarty A, Moore KJ, Smutko JS, Mays GG, Woolf EA, Monroe CA, Tepper RI: Identification and expression cloning of a leptin receptor, OB-R. Cell 83:1263-1271, 1995
3. Lee GH, Proenca R, Montez JM, Carroll KM, Darvishzadeh JG, Lee JI, Friedman JM: Abnormal splicing of the leptin receptor in diabetic mice. Nature 379:632-635, 1996
4. Chen H, Charlat O, Tartaglia LA, Woolf EA, Weng X, Ellis SJ, Lakey ND, Culpepper J, Moore KJ, Breitbart RE, Duyk GM, Tepper RI, Morgenstern JP: Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell 84:491-495, 1996
5. Pelleymounter MA, Cullen MJ, Baker MB, Hecht R, Winters D, Boone T, Collins F: Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269:540-543, 1995
6. Halaas JL, Gajiwala KS, Maffei M, Cohen SL, Chait BT, Rabinowitz D, Lallone RL, Burley SK, Friedman JM: Weight-reducing effects of the plasma protein encoded by the obese gene. Science 269:543-546, 1995
7. Collins S, Kuhn CM, Petro AE, Swick AG, Chrunyk BA, Surwit RS: Role of leptin in fat regulation (Letter). Nature 380:677, 1996
8. Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P: Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 269:546-549, 1995
9. Bray GA, York DA: Hypothalamic and genetic obesity in experimental animals: an autonomic and endocrine hypothesis. Physiol Rev 59:719-809, 1979
10. Strobel A, Issad T, Camoin L, Ozata M, Strasbourg AD: A leptin missense mutation associated with hypogonadism and morbid obesity. Nat Gen 18:213-215, 1998
11. Montague CT, Farooqi IS, Whitehead JP, Soos MA, Rau H, Wareham NJ, Sewter CP, Digby JE, Mohammed SN, Hurst JA, Cheetham CH, Earley AR, Barnett AH, Prins JB, O'Rahilly S: Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature 387:903-908, 1997
12. Farooqi IS, Jebb SA, Langmack G, Lawrence E, Cheetham CH, Prentice AM, Hughes IA, McCamish MA, O'Rahilly S: Effects of recombinant leptin therapy in a child with congenital leptin deficiency. N Engl J Med 341:879-883, 1999
13. Levin N, Nelson C, Gurney A, Vandlen R, DeSauvage F: Decreased food intake does not completely account for adiposity reduction after ob protein infusion. Proc Natl Acad Sci U S A 93:1726-1730, 1996
14. Sindelar DK, Havel PJ, Seeley RJ, Wilkinson CW, Woods SC, Schwartz MW: Low plasma leptin levels contribute to diabetic hyperphagia in rats. Diabetes 48:1275-1280, 1999
15. Maffei M, Halaas J, Ravussin E, Pratley RE, Lee GH, Zhang Y, Fei H, Kim S, Lallone R, Ranganathan S, Kern PA, Friedman JM: Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med 1:1155-1161, 1995
16. Considine RV, Sinha MK, Heiman ML, Kriaugiunas A, Stephens TW, Nyce MR, Ohannesian JP, Marco CC, McKee LJ, Bauer TL, Caro JF: Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med 334:292-295, 1996
17. Lonnqvist F, Arner P, Nordfors L, Schalling M: Overexpression of the obese (ob) gene in adipose tissue of human obese subjects. Nat Med 1:950-953, 1995
18. Hamilton BS, Paglia D, Kwan AYM, Deitel M: Increased obese mRNA expression in omental fat cells from massively obese humans. Nat Med 1:953-956, 1995
19. Frederich RC, Hamann A, Anderson S, Lollmann B, Lowell BB, Flier J: Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action. Nat Med 1:1311-1314, 1995
20. Ravussin E, Pratley RE, Maffei M, Wang H, Friedman JM, Bennett PH, Bogardus C: Relatively low plasma leptin concentrations precede weight gain in Pima Indians. Nat Med 3:238-240, 1997
21. Matkovic V, Ilich JZ, Badenhop NE, Skugor M, Clairmont A, Klisovic D, Landoll JD: Gain in body fat is inversely related to the nocturnal rise in serum leptin level in young females. J Clin Endocrinol Metab 82:1368-1372, 1997
22. Matkovic V, Ilich JZ, Skugor M, Badenhop NE, Goel P, Clairmont A, Klisovic D, Nahhas RW, Landoll JD: Leptin is inversely related to age at menarche in human females. J Clin Endocrinol Metab 82:3239-3245, 1997
23. Ahmed ML, Ong KKL, Morrell DJ, Cox L, Drayer N, Perry L, Preece MA, Dunger DB: Longitudinal study of leptin concentrations during puberty: sex differences and relationship to changes in body composition. J Clin Endocrinol Metab 84:899-905, 1999
24. Hodge AM, de Courten MP, Dowse GK, Zimmet PZ, Collier GR, Gareeboo H, Chitson P, Fareed D, Hemraj F, Alberti KGMM, Tuomilehto J: Do leptin levels predict weight gain? A 5-year follow-up study in Mauritius. Obes Res 6:319-325, 1990
25. Chessler SD, Fujimoto WY, Shofer JB, Boyko EJ, Weigle DS: Increased plasma leptin levels are associated with fat accumulation in Japanese Americans. Diabetes 47:239-243, 1998
26. Weigle DS, Duell PB, Connor WE, Steiner RA, Soules MR, Kuijper JL: Effect of fasting, refeeding, and dietary fat restriction on plasma leptin levels. J Clin Endocrinol Metab 82:561-565, 1997
27. Schrauwen P, van Marken Lichtenbelt WD, Westerterp KR, Saris WHM: Effect of diet composition on leptin concentration in lean subjects. Metabolism 46:420-424, 1997
28. Havel PJ, Townsend R, Chaump L, Teff K: High-fat meals reduce 24-h circulating leptin concentrations in women. Diabetes 48:334-341, 1999
29. Surwit RS, Kuhn CM, Cochrane C, McCubbin JA, Feinglos MN: Diet-induced type II diabetes in C57BL/6J mice. Diabetes 37:1163-1167, 1988
30. Surwit RS, Feinglos MN, Rodin J, Sutherland A, Petro AE, Opara EC, Kuhn CM, Rebuffe-Scrive M: Differential effects of fat and sucrose on the development of obesity and diabetes in C57BL/6J and A/J mice. Metabolism 44:645-651, 1995
31. Mills E, Kuhn CM, Feinglos MN, Surwit RS: Hypertension in C57BL/6J mouse model of non-insulin dependent diabetes mellitus. Am J Physiol 264:R73-R78, 1993
32. Brownlow BS, Petro A, Feinglos MN, Surwit RS: The role of motor activity in diet-induced obesity in C57BL/6J mice. Physiol Behav 60:37-41, 1996
33. Surwit RS, Petro AE, Parekh P, Collins S: Low plasma leptin in response to dietary fat in diabetes and obesity-prone mice. Diabetes 40:1516-1520, 1997
34. Ring BD, Scully S, Davis CR, Baker MB, Cullen MJ, Pelleymounter MA, Danilenko DM: Systemically and topically administered leptin both accelerate wound healing in diabetic ob/ob mice. Endicrinology 141:446-449, 2000
35. Sierra-Honigmann MR, Nath AK, Murakami C, Garcia-Cardena G, Papapetropoulos A, Sessa WC, Madge LA, Scheduler JS, Schwabb MB, Polverini PJ, Flores-Riveros JR: Biological action of leptin as an angiogenic factor. Science 281:1683-1686, 1998
36. 3 AR agonist treatment of diet-induced obesity in mice. Endocrinology 138:405-413, 1997
37. Heymsfield SB, Greenberg AS, Fujioka K, Dixon RM, Kushner R, Hunt T, Lubina JA, Patane J, Self B, Hunt P, McCamish M: Recombinant leptin for weight loss in obese and lean adults: a randomized, controlled, close-escalation trial. JAMA 282:1568-1575, 1999
38. Friedman JM, Halaas JL: Leptin and the regulation of body weight in mammals. Nature 395:763-770, 1998