Low plasma leptin in response to dietary fat in diabetes- and obesity- prone mice

Diabetes

Volumn 46, Issue 9, 1997, Pages 1516-1520

  Surwit, Richard S ^a,b   Petro, Ann E ^a   Parekh, Priti ^a   Collins, Sheila ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DUKE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN;

ADIPOCYTE; ANIMAL MODEL; ARTICLE; BODY WEIGHT; DIABETES MELLITUS; DIETARY INTAKE; DISEASE PREDISPOSITION; FAT INTAKE; MALE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; WEIGHT GAIN;

EID: 0030804112     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.46.9.1516     Document Type: Article

References (31)

1. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM: Positional cloning of the mouse obese gene and its human homologue. Nature 372:425-479, 1994
2. Tartaglia LA, Dembski M, Weng X, Deng N, Culpepper J, Devos R, Richards GJ, Campfield LA, Clark FT, Deeds J, Muir C, Sanker S, Moriarty A, Moore KJ, Smutko JS, Mays GG, Woolf EA, Monroe CA, Tepper RI: Identification and expression cloning of a leptin receptor, OB-R. Cell 83:1263-1271, 1995
3. Lee G-H; Proenca R, Montez JM, Carrol, KM, Darbishzadeh JG, Lee JI, Friedman JM: Abnormal splicing of the leptin receptor in diabetic mice. Nature 379:632-635, 1996
4. Chen H, Charlat O, Tartaglia LA, Woolf, EA, Weng Z, Ellis SJ, Lakery ND, Culpepper J, Moore KJ, Breitbart TE, Duyk GM, Tepper RI, Morgenstern JP: Evidence that the diabetes gene encodes the leptin receptor identification of a mutation in the leptin receptor gene in db/db mice. Cell 84:491-495, 1996
5. Considine RV, Considine EL, Williams CJ, Nyce MR, Magosin SA, Bauer TL, Rosato EL, Colberg J, Caro JF: Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity. J Clin Invest 95:2986-2988, 1995
6. Considine RV, Considine EL, Williams CJ, Hyde TM, Caro JF: The hypothalamic leptin receptor in humans: identification of incidental sequence polymorphisms and absence of the db/db mouse and fa/fa rat mutations. Diabetes 19:992-994,1996
7. Maffei M, Fei H, Lee G-H, Dani C, Leroy P, Zhang Y, Proenca R, Negrel R, Ailhaud G, Friedman JM: Increased expression in adipocytes of ob RNA in mice with lesions of the hypothalamus and with mutations at the db locus. Nature Genet 92:6957-6960, 1995
8. Ogawa Y, Masuzki H, Isse N, Okazaki T, Mori K, Shigemoto M, Satoh N, Tamura N, Hosoda K, Yoshimasa Y, Jingami H, Kawada T, Nakao K: Molecular cloning of rat obese cDNA and augmented gene expression in genetically obese Zucker Fatty (fa/fa) rats. J Clin Invest 96:1647-1652, 1995
9. Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW, Nyce MR, Ohannesian JP, Marco CC, McKee LJ, Bauer TL, Caro JF: Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med 334:292-295, 1996
10. Collins S, Surwit RS: Pharmacological manipulation of ob gene expression in a dietary model of obesity. J Biol Chem 271:9437-9440, 1996
11. Surwit RS, Kuhn CM, Cochrane C, McCubbin JA, Feinglos MN: Diet-induced type II diabetes in C57BL/6J mice. Diabetes 37:1163-1167, 1988
12. West DB, Boozer CN, Moody DL, Atkinson RL: Dietary obesity in nine inbred mouse strains. Am J Physiol 262:R1025-R1032, 1992
13. Rebuffe-Scrive M, Surwit R, Feinglos M, Kuhn C, Rodin J: Regional fat distribution and metabolism in a new mouse model (C57BL/6J) of non-insulin-dependent diabetes mellitus. Metab Clin Exp 42:1405-1409, 1993
14. Surwit RS, Feinglos MN, Rodin J, Sutherland A, Petro AE, Opara EC, Kuhn CM, Rebuffe-Scrive M: Differential effects of fat and sucrose on the development of obesity and diabetes in C57BL/6J and A/J mice. Metabolism 44:645-651, 1995
15. Coleman DL: Diabetes-obesity syndromes in mice. Diabetes 31:1-6, 1982
16. Mills E, Kuhn CM, Feinglos MN, Surwit RS: Hypertension in C57BL/6J mouse model of non-insulin-dependent diabetes mellitus. Am J Physiol 264:R73-R78, 1993
17. Lee SK, Opara EC, Surwit RS, Feinglos MN, Akwari OE: Defective glucosestimulated insulin release from perifused islets of C57BL/6J mice. Pancreas 11:206-211, 1995
18. Wencel HE, Smothers C, Opara EC, Kuhn CM, Feinglos MS, Surwit RS: Impaired second phase insulin response of diabetes-prone C57BL/6J mouse islets. Physiol Behav 57:1215-1220, 1995
19. Rentsch J, Chiesi M: Regulation of ob gene mRNA levels in cultured adipocytes. FEBS Lett 379:55-59, 1996
20. Leroy P, Dessolin S, Villageois P, Moon BC, Friedman JM, Ailhaud G, Dani C: Expression of ob gene in adipose cells. J Biol Chem 271:2365-2368, 1996
21. Gettys TW, Harkness PJ, Watson PM: The beta3-adrenergic receptor inhibits insulin-stimulated leptin secretion from isolated rat adipocytes. Endocrinology 137:4054-4057, 1996
22. Saladin R, de Vos P, Guerre-Millo M, Leturque A, Girard J, Staels B, Auwerx J: Transient increase in obese gene expression after food intake or insulin administration. Nature 377:527-529, 1995
23. Collins S, Kuhn CM, Petro AE, Swick AG, Chrunyk BA, Surwit RS: Role of leptin in fat regulation. Nature 380:677, 1996
24. Fleury C, Neverova M, Collins S, Raimbault S, Champigny O, Levi-Meyrueis C, Bouillard F, Seldin MF, Surwit RS, Ricquier D, Warden CH: Uncoupling protein-2: a novel gene linked to obesity and diabetes. Nature Genet 15:269-272, 1997
25. Pelleymounter MA, Cullen MJ, Baker MB, Hecht R, Winters D, Boone T, Collins F: Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269:540-543, 1995
26. Halaas JL, Gajiwala KS, Maffei M, Cohen SL, Chait BT, Rabinowitz D, Lallone RL, Burley SK, Friedman JM: Weight-reducing effects of the plasma protein encoded by the obese gene. Science 269:543-546, 1995
27. Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P: Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 269:546-549, 1995
28. Rothwell NJ, Stock MJ: A role for brown adipose tissue in diet-induced thermogenesis. Nature 281:31-35, 1979
29. Brooks SL, Rothwell NJ, Stock MJ, Goodbody AE, Trayhurn P: Increased proton conductance pathway in brown adipose tissue mitochondria of rats exhibiting diet-induced thermogenesis. Nature 286:274-276, 1980
30. Ravussin E, Pratley RE, Maffei M, Wang H, Friedman JM, Bennett PH, Bogardus C: Low plasma leptin concentrations precede weight gain in Pima Indians. Nature Med 3:238-240, 1997
31. Spraul M, Ravussin E, Fontwieille AM, Rising R, Larson DE, Anderson EA: Reduced sympathetic nervous system activity: a potential mechanism predisposing to body weight gain. J Clin Invest 92:1730-1735, 1993