메뉴 건너뛰기




Volumn 57, Issue 3, 2000, Pages 863-874

Understanding hypertension through genetic manipulation in mice

Author keywords

Animal models; Genetics of disease; Hypertension; Knockout mouse; Mouse models; Renin angiotensin system; Transgenic mouse

Indexed keywords

BRADYKININ B2 RECEPTOR; DOPAMINE RECEPTOR; ENDOTHELIN 1; NITRIC OXIDE SYNTHASE;

EID: 0033917514     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2000.057003863.x     Document Type: Conference Paper
Times cited : (38)

References (103)
  • 1
    • 0020645067 scopus 로고
    • Gene transfers into mouse embryos: Production of transgenic mice by pronuclear injection
    • GORDON JW, RUDDLE FH: Gene transfers into mouse embryos: Production of transgenic mice by pronuclear injection. Methods Enzymol 101:411-433, 1983
    • (1983) Methods Enzymol , vol.101 , pp. 411-433
    • Ruddle Fh, G.J.W.1
  • 3
    • 0027386012 scopus 로고
    • Manipulating genes to understand cardiovascular diseases: Major approaches for introducing genes into cells
    • SIGMUND CD: Manipulating genes to understand cardiovascular diseases: Major approaches for introducing genes into cells. Hypertension 22:599-607, 1993
    • (1993) Hypertension , vol.22 , pp. 599-607
    • Sigmund, C.D.1
  • 4
    • 0023663887 scopus 로고
    • Position-independent, high-level expression of the human betaglobin gene in transgenic mice
    • GROSVELD F, VAN ASSENDELFT GB, GREAVES DR, KOLLIAS G: Position-independent, high-level expression of the human betaglobin gene in transgenic mice. Cell 51:975-985, 1987
    • (1987) Cell , vol.51 , pp. 975-985
    • Grosveld, F.1    Van Assendelft, G.B.2    Greaves, D.R.3    Kollias, G.4
  • 5
    • 0031910886 scopus 로고    scopus 로고
    • Regulatory elements required for human 1 angiotensinogen expression in HepG2 cells are dispensable in transgenic mice
    • YANG G, SIGMUND CD: Regulatory elements required for human 1 angiotensinogen expression in HepG2 cells are dispensable in transgenic mice. Hypertension 31:734-740, 1998
    • (1998) Hypertension , vol.31 , pp. 734-740
    • Sigmund Cd, Y.G.1
  • 6
    • 0028135079 scopus 로고
    • Altering mice by homologous recombination using embryonic stem cells
    • BRONSON SK, SMITHIES O: Altering mice by homologous recombination using embryonic stem cells. J Biol Cliem 269:27155-27158, 1994
    • (1994) J Biol Cliem , vol.269 , pp. 27155-27158
    • Smithies O, B.S.K.1
  • 7
    • 0019826665 scopus 로고    scopus 로고
    • Establishment in culture of pluripotential cells from mouse embryos
    • EVANS MJ, KAUFMAN MH: Establishment in culture of pluripotential cells from mouse embryos. Nature 292:154-156, 19S1
    • Nature , vol.292 , pp. 154-156
    • Kaufman Mh, E.M.J.1
  • 8
    • 0024328536 scopus 로고
    • Altering the genome by homologous recombination
    • CAPECCIII MR: Altering the genome by homologous recombination. Science 244:1288-1292, 1989
    • (1989) Science , vol.244 , pp. 1288-1292
    • Capecciii, M.R.1
  • 11
    • 0025322560 scopus 로고
    • Generation of transgenic mice \vilh elevated blood pressure by introduction of the rat renin and angiotensinogen genes
    • YOKOYAMA M, NOMURA T, KATSUKi M, NAKANisiii S: Generation of transgenic mice \vilh elevated blood pressure by introduction of the rat renin and angiotensinogen genes. Proc Nail Acad Sei USA 87:5153-5157, 1990
    • (1990) Proc Nail Acad Sei USA , vol.87 , pp. 5153-5157
    • Yokoyama, M.1    Nomura, T.2    Katsuki, M.3    Nakanisiii, S.4
  • 13
    • 0027361720 scopus 로고
    • Expression of the human renin gene in transgenic mice throughout ontogeny
    • SIGMUND CD: Expression of the human renin gene in transgenic mice throughout ontogeny. Pediatr Nephrol 7:639-645, 1993
    • (1993) Pediatr Nephrol , vol.7 , pp. 639-645
    • Sigmund, C.D.1
  • 14
    • 0026514648 scopus 로고
    • Regulated tissue- And cell-specific expression of the human renin gene in transgenic mice
    • SIGMUND CD, JONES CA, KANE CM, Wu C, LANG JA, GROSS KW: Regulated tissue- and cell-specific expression of the human renin gene in transgenic mice. Circ Res 70:1070-1079, 1992
    • (1992) Circ Res , vol.70 , pp. 1070-1079
    • Sigmund, C.D.1    Jones, C.A.2    Kane, C.M.3    Wu C4    Lang, J.A.5    Gross, K.W.6
  • 16
    • 0031804598 scopus 로고    scopus 로고
    • Developmental expression of human angiotensinogen in transgenic mice
    • YANG G, SIGMUND CD: Developmental expression of human angiotensinogen in transgenic mice. Am J Pliysiol 274:F932-F939, 1998
    • (1998) Am J Pliysiol , vol.274
    • Sigmund Cd, Y.G.1
  • 18
    • 0028301777 scopus 로고
    • Comparative studies on species-specific reactivity between renin and angiotensinogen
    • HATAE T, TAKIMOTO E, MURAKAMI K, FUKAMIZU A: Comparative studies on species-specific reactivity between renin and angiotensinogen. Mol Cell Biochem 131:43-47, 1994
    • (1994) Mol Cell Biochem , vol.131 , pp. 43-47
    • Hatae, T.1    Takimoto, E.2    Murakami, K.3    Fukamizu, A.4
  • 19
    • 0027190950 scopus 로고
    • Chimeric renin-angiotensin system demonstrates sustained increase in blood pressure of transgenic mice carrying both human renin and human aneiotensinogen eenes.7
    • FUKAMIZU A, SUGI.MURA K, TAKIMOTO E, SUGIYAMA F, SEO M-S, TAKAIIASIII S, HATAE T, KAJIWARA N, YAGAMI K, MURAKAMI K: Chimeric renin-angiotensin system demonstrates sustained increase in blood pressure of transgenic mice carrying both human renin and human aneiotensinogen eenes.7 Biol Chem 268:1161711621, 1993
    • (1993) Biol Chem , vol.268 , pp. 1161711621
    • Fukamizu, A.1    Sugi.mura, K.2    Takimoto, E.3    Sugiyama, F.4    Seo, M.-S.5    Takaiiasiii, S.6    Hatae, T.7    Kajiwara, N.8    Yagami, K.9    Murakami, K.10
  • 20
    • 0030049446 scopus 로고    scopus 로고
    • Chronic hypertension and altered baroreflex responses in transgenic mice containing the human renin and human angiotensinogen genes
    • MERRILL DC,THOMPSON MW, CAR.NEY C, SCHLAGER G, ROBILLARD JE, SIGMUND CD: Chronic hypertension and altered baroreflex responses in transgenic mice containing the human renin and human angiotensinogen genes. J Clin Invest 97:1047-1055, 1996
    • (1996) J Clin Invest , vol.97 , pp. 1047-1055
    • Merrill, D.C.1    Thompson, M.W.2    Car.ney, C.3    Schlager, G.4    Robillard, J.E.5    Sigmund, C.D.6
  • 21
    • 0030575910 scopus 로고    scopus 로고
    • Hypertension induced in pregnant mice by placental renin and maternal angiotensinogen
    • TAKIMOTO E, ISIIIDA J, SUGIYAMA F, HORIGUCHI H, MURAKAMI K, FUKAMIZU A: Hypertension induced in pregnant mice by placental renin and maternal angiotensinogen. Science 274:995-998, 1996
    • (1996) Science , vol.274 , pp. 995-998
    • Takimoto, E.1    Isiiida, J.2    Sugiyama, F.3    Horiguchi, H.4    Murakami, K.5    Fukamizu, A.6
  • 22
    • 0033616351 scopus 로고    scopus 로고
    • The angiotensinogen gene is expressed in both astrocytes and neurons in murine central nervous system
    • YANG G, GRAY TS, SIGMUND CD, CASSELL MD: The angiotensinogen gene is expressed in both astrocytes and neurons in murine central nervous system. Brain Res 817:123-131, 1999
    • (1999) Brain Res , vol.817 , pp. 123-131
    • Yang, G.1    Gray, T.S.2    Sigmund, C.D.3    Cassell, M.D.4
  • 23
    • 0032538972 scopus 로고    scopus 로고
    • The brain renin-angiotensin system contributes to the hypertension exhibited by mice containing both human renin and human angiotensinogen transgenes
    • DAVISSON RL, YANG G, BELTZ TG, CASSELL MD, JOHNSON AK, SIGMUND CD: The brain renin-angiotensin system contributes to the hypertension exhibited by mice containing both human renin and human angiotensinogen transgenes. Circ Res 83:1047-1058, 1998
    • (1998) Circ Res , vol.83 , pp. 1047-1058
    • Davisson, R.L.1    Yang, G.2    Beltz, T.G.3    Cassell, M.D.4    Johnson, A.K.5    Sigmund, C.D.6
  • 24
    • 0030736087 scopus 로고    scopus 로고
    • The kidney androgen-regulated protein (KAP) promoter confers renal proximal tubule cell-specific and highly androgen-responsive expression on the human angiotensinogen gene in transgenic mice
    • DING Y, DAVISSON RL, HARDY DO, Znu L-J, MERRILL DC, CATTERALL JF, SIGMUND CD: The kidney androgen-regulated protein (KAP) promoter confers renal proximal tubule cell-specific and highly androgen-responsive expression on the human angiotensinogen gene in transgenic mice./ Biol Cliem 272:28142-28148,1997
    • (1997) Biol Cliem , vol.272 , pp. 28142-28148
    • Ding, Y.1    Davisson, R.L.2    Hardy, D.O.3    Znu, L.-J.4    Merrill, D.C.5    Catterall, J.F.6    Sigmund, C.D.7
  • 25
    • 0033564984 scopus 로고    scopus 로고
    • Novel mechanism of hypertension revealed by cell-specific targeting of human angiotensinogen in transgenic mice
    • DAVISSON RL, DING Y, STEC DE, CATTERALL JF, SIGMUND CD: Novel mechanism of hypertension revealed by cell-specific targeting of human angiotensinogen in transgenic mice. Pliysiol Genome 1:3-9, 1999
    • (1999) Pliysiol Genome , vol.1 , pp. 3-9
    • Davisson, R.L.1    Ding, Y.2    Catterall, J.F.3    Sigmund, C.D.4
  • 26
    • 0025239301 scopus 로고
    • Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene
    • MULLINS JJ, PETERS J, GANTEN D: Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene. Nature 344:541544, 1990
    • (1990) Nature , vol.344 , pp. 541544
    • Mullins, J.J.1    Peters, J.2    Ganten, D.3
  • 28
    • 0020427036 scopus 로고
    • A DNA polymorphism, consistent with gene duplication, correlates with high renin levels in the mouse submaxillary gland
    • PICCINI N, KNOPF JL, GROSS KW: A DNA polymorphism, consistent with gene duplication, correlates with high renin levels in the mouse submaxillary gland. Cell 30:205-213, 1982
    • (1982) Cell , vol.30 , pp. 205-213
    • Piccini, N.1    Knopf, J.L.2    Gross, K.W.3
  • 29
    • 0024296566 scopus 로고
    • Close physical linkage of the murine Ren-1 and Ren-2 loci
    • ABEL KJ, GROSS KW: Close physical linkage of the murine Ren-1 and Ren-2 loci. Nucleic Acids Res 16:2111-2126, 1988
    • (1988) Nucleic Acids Res , vol.16 , pp. 2111-2126
    • Gross Kw, A.K.J.1
  • 32
    • 0030952323 scopus 로고    scopus 로고
    • Complementation of reduced survival, hypotension and renal abnormalities in angiotensinogen deficient mice by the human renin and human angiotensinogen genes
    • DAVISSON RL, KIM HS, KREGE JH, LAGER DJ, SMITHIES O, SIGMUND CD: Complementation of reduced survival, hypotension and renal abnormalities in angiotensinogen deficient mice by the human renin and human angiotensinogen genes. J Clin Invest 99:1258-1264, 1997
    • (1997) J Clin Invest , vol.99 , pp. 1258-1264
    • Davisson, R.L.1    Kim, H.S.2    Krege, J.H.3    Lager, D.J.4    Smithies, O.5    Sigmund, C.D.6
  • 34
    • 0031917365 scopus 로고    scopus 로고
    • Angiotensinogen gene null-mutant mice lack homeostatic regulation of glomerular filtration and tubular reabsorption
    • OKUBO S, NIIMURA F, MATSUSAKA T, FOGO A, HOGAN BL, IcinKAWA I: Angiotensinogen gene null-mutant mice lack homeostatic regulation of glomerular filtration and tubular reabsorption. Kidney bit 53:617-625, 1998
    • (1998) Kidney Bit , vol.53 , pp. 617-625
    • Okubo, S.1    Niimura, F.2    Matsusaka, T.3    Fogo, A.4    Hogan, B.L.5    Icinkawa, I.6
  • 36
    • 0029925360 scopus 로고    scopus 로고
    • Mice lacking angiotensin-converting enzyme have low blood pressure, renal pathology, and reduced male fertility
    • ESTHER CR JR, HOWARD TE, MARINO EM, GODDARD JM, CAPECCHI MR, BERNSTEIN KE: Mice lacking angiotensin-converting enzyme have low blood pressure, renal pathology, and reduced male fertility. Lab Invest 74:953-965, 1996
    • (1996) Lab Invest , vol.74 , pp. 953-965
    • Esther, C.R.R.1    Howard, T.E.2    Marino, E.M.3    Goddard, J.M.4    Capecchi, M.R.5    Bernstein, K.E.6
  • 41
    • 0030851754 scopus 로고    scopus 로고
    • Effects of angiotensin II in mice lacking AT1A angiotensin receptors: A role for ATI B receptors in blood pressure regulation
    • OLIVERIO MI, BEST CF, KIM H-S, ARENDSHORST WJ, SMITHIES O, COFFMAN TM: Effects of angiotensin II in mice lacking AT1A angiotensin receptors: A role for ATI B receptors in blood pressure regulation. Am J Pliysiol 272:F515-F520, 1997
    • (1997) Am J Pliysiol , vol.272
    • Oliverio, M.I.1    Best, C.F.2    Kim, H.-S.3    Arendshorst, W.J.4    Smithies, O.5    Coffman, T.M.6
  • 42
  • 47
    • 0032416477 scopus 로고    scopus 로고
    • Reduced growth, abnormal kidney structure, and type 2 (AT2) angiotensin receptor-mediated blood pressure regulation in mice lacking both ATI a and AT1B receptors for angiotensin II
    • OLIVERIO MI, KIM HS, ITO M, LE T, AUDOLY L, BEST CF, HILLER S, KLUCKMAN K, MAEDA N, SMITHIES O, COFFMAN TM: Reduced growth, abnormal kidney structure, and type 2 (AT2) angiotensin receptor-mediated blood pressure regulation in mice lacking both ATI A and AT1B receptors for angiotensin II. Proc Nat! Acad Sei USA 95:15496-15501, 1998
    • (1998) Proc Nat! Acad Sei USA , vol.95 , pp. 15496-15501
    • Oliverio, M.I.1    Kim, H.S.2    Ito, M.3    Audoly, L.4    Best, C.F.5    Hiller, S.6    Kluckman, K.7    Maeda, N.8    Smithies, O.9    Coffman, T.M.10
  • 48
    • 0028885773 scopus 로고
    • Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor in mice
    • HEIN L, BARSH GS, PRATT RE, DZAU VJ, KOBILKA BK: Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor in mice. Nature 377:744-747, 1995
    • (1995) Nature , vol.377 , pp. 744-747
    • Hein, L.1    Barsh, G.S.2    Pratt, R.E.3    Dzau, V.J.4    Kobilka, B.K.5
  • 50
    • 0030740380 scopus 로고    scopus 로고
    • Renin-1 is essential for normal renal juxtaglomerular cell granulation and macula densa morphology
    • CLARK AF, SHARP MF, MORLEY SD, FLEMING S, PETERS J, MULLINS JJ: Renin-1 is essential for normal renal juxtaglomerular cell granulation and macula densa morphology. J Biol Cliem 272:1818518190, 1997
    • (1997) J Biol Cliem , vol.272 , pp. 1818518190
    • Clark, A.F.1    Sharp, M.F.2    Morley, S.D.3    Fleming, S.4    Peters, J.5    Mullins, J.J.6
  • 52
    • 0023505509 scopus 로고
    • Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide
    • IGNARRO LJ, BUGA GM, WOOD KS, BYRNS RE, CHAUDHURI G: Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc Natl Acad Sei USA 84:92659269, 1987
    • (1987) Proc Natl Acad Sei USA , vol.84 , pp. 92659269
    • Ignarro, L.J.1    Buga, G.M.2    Wood, K.S.3    Byrns, R.E.4    Chaudhuri, G.5
  • 53
    • 0023198721 scopus 로고
    • Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
    • PALMER RM, FERRIGE AG, MONCADA S: Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 327:524-526, 1987
    • (1987) Nature , vol.327 , pp. 524-526
    • Palmer, R.M.1    Ferrige, A.G.2    Moncada, S.3
  • 54
    • 0028889439 scopus 로고
    • Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death
    • LAUBACII VE, SHESELY EG, SMITHIES O, SHERMAN PA: Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death. Proc Natl Acad Sei USA 92:10688-10692, 1995
    • (1995) Proc Natl Acad Sei USA , vol.92 , pp. 10688-10692
    • Laubacii, V.E.1    Shesely, E.G.2    Smithies, O.3    Sherman, P.A.4
  • 55
  • 57
    • 0032520153 scopus 로고    scopus 로고
    • Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling
    • Runic RD, SHESELY EG, MAEDA N, SMITHIES O, SEGAL SS, SESSA WC: Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling. J Clin Invest 101:731-736, 1998
    • (1998) J Clin Invest , vol.101 , pp. 731-736
    • Runic, R.D.1    Shesely, E.G.2    Maeda, N.3    Smithies, O.4    Segal, S.S.5    Sessa, W.C.6
  • 58
    • 0031952267 scopus 로고    scopus 로고
    • Responses of carotid artery in mice deficient in expression of the gene for endothelial NO synthase
    • FARACI FM, SIGMUND CD, SIIESELY EG, MAEDA N, HEISTAD DD: Responses of carotid artery in mice deficient in expression of the gene for endothelial NO synthase. Am J Pliysiol 274:H564-H570, 1998
    • (1998) Am J Pliysiol , vol.274
    • Faraci, F.M.1    Sigmund, C.D.2    Siiesely, E.G.3    Maeda, N.4    Heistad, D.D.5
  • 59
    • 0029005588 scopus 로고
    • Effect of inhibiting renal kallikrein on prostaglandin E2, water, and sodium excretion
    • SAITOII S, SCICLI AG, PETERSON E, CARRETERO OA: Effect of inhibiting renal kallikrein on prostaglandin E2, water, and sodium excretion. Hypertension 25:1008-1013, 1995
    • (1995) Hypertension , vol.25 , pp. 1008-1013
    • Saitoii, S.1    Scicli, A.G.2    Peterson, E.3    Carretero, O.A.4
  • 60
    • 0027263226 scopus 로고
    • Kinin actions on renal papillary blood flow and sodium excretion
    • MATTSON DL, COWLEY AW JR: Kinin actions on renal papillary blood flow and sodium excretion. Hypertension 21:961-965,1993
    • (1993) Hypertension , vol.21 , pp. 961-965
    • Cowley Aw, M.D.L.1
  • 61
    • 85026151937 scopus 로고    scopus 로고
    • Effect of high salt intake in mutant mice lacking bradykinin-B2 receptors
    • ALFIE ME, SIGMON DH, POMPOSIELLO SI, CARRETERO OA: Effect of high salt intake in mutant mice lacking bradykinin-B2 receptors. Hypertension 29:483-487, 1997
    • (1997) Hypertension , vol.29 , pp. 483-487
    • Alfie, M.E.1    Sigmon, D.H.2    Pomposiello, S.I.3    Carretero, O.A.4
  • 68
    • 0022975962 scopus 로고    scopus 로고
    • Release of atrial natriuretic factor: Effects of repetitive stretch and temperature
    • BILDER GE, SCHOFIELD TL, BLAINE EH: Release of atrial natriuretic factor: Effects of repetitive stretch and temperature. Am J Pliysiol 251:F817-F821, 19S6
    • Am J Pliysiol , vol.251 , pp. 817-821
    • Bilder, G.E.1    Schofield, T.L.2    Blaine, E.H.3
  • 69
    • 0022599561 scopus 로고
    • The character of the atrial natriuretic response: Pressure and volume effects
    • BLAINE EH, HEINEL LA, SCIIORN T\V, MARSH EA, WIHNNERY MA: The character of the atrial natriuretic response: Pressure and volume effects. J Hypertens (Suppl 4):S17-S24, 1986
    • (1986) J Hypertens Suppl , vol.4
    • Blaine, E.H.1    Heinel, L.A.2    Marsh, E.A.3    Wihnnery, M.A.4
  • 70
    • 0023272139 scopus 로고
    • Atrial natriuretic peptide inhibits angiotensin-stimulated proximal tubular sodium and water reabsorption
    • HARRIS PJ, THOMAS D, MORGAN TO: Atrial natriuretic peptide inhibits angiotensin-stimulated proximal tubular sodium and water reabsorption. Nature 326:697-698, 1987
    • (1987) Nature , vol.326 , pp. 697-698
    • Harris, P.J.1    Thomas, D.2    Morgan, T.O.3
  • 72
    • 0031939535 scopus 로고    scopus 로고
    • Salt-sensitive hypertension in ANP knockout mice: Potential role of abnormal plasma renin activity
    • MELO LG, VERESS AT, CIIONG CK, PANG SC, FLYNN TG, SONNENBERG H: Salt-sensitive hypertension in ANP knockout mice: Potential role of abnormal plasma renin activity. Am J Pliysiol 274:R255-R261, 1998
    • (1998) Am J Pliysiol , vol.274
    • Melo, L.G.1    Veress, A.T.2    Ciiong, C.K.3    Pang, S.C.4    Flynn, T.G.5    Sonnenberg, H.6
  • 73
    • 0028973389 scopus 로고
    • Salt-resistant hypertension in mice lacking the guanylyl cyclase-A receptor for atrial natriuretic peptide
    • LOPEZ MJ, WONG SKF, KISIIIMOTO I, DUBOIS S, MACH V, FRIESEN J, GARBERS DL, BEUVE A: Salt-resistant hypertension in mice lacking the guanylyl cyclase-A receptor for atrial natriuretic peptide. Nature 378:65-68, 1995
    • (1995) Nature , vol.378 , pp. 65-68
    • Lopez, M.J.1    Skf, W.2    Kisiiimoto, I.3    Dubois, S.4    Mach, V.5    Friesen, J.6    Garbers, D.L.7    Beuve, A.8
  • 83
    • 0031797909 scopus 로고    scopus 로고
    • Modifiable gene expression in kidney: Kidney-specific deletion of a target gene via the cre-loxP system
    • STEC DE, SIGMUND CD: Modifiable gene expression in kidney: Kidney-specific deletion of a target gene via the cre-loxP system. Exp Nephrol 6:568-575, 1998
    • (1998) Exp Nephrol , vol.6 , pp. 568-575
    • Sigmund Cd, S.D.E.1
  • 84
    • 0031799964 scopus 로고    scopus 로고
    • Ventricular muscle-restricted targeting of the RXRalpha gene reveals a non-cell-autonomous requirement in cardiac chamber morphogenesis
    • CIIEN J, KUBALAK SW, CHIEN KR: Ventricular muscle-restricted targeting of the RXRalpha gene reveals a non-cell-autonomous requirement in cardiac chamber morphogenesis. Development 125:1943-1949, 199S
    • Development , vol.125 , pp. 1943-1949
    • Ciien, J.1    Kubalak, S.W.2    Chien, K.R.3
  • 86
    • 0033534685 scopus 로고    scopus 로고
    • The influence of chromosomal location on the expression of two transgenes in mice
    • HATADA S, KUZIEL W, SMITHIES O, MAEDA N: The influence of chromosomal location on the expression of two transgenes in mice. J Biol Cliem 274:948-955, 1999
    • (1999) J Biol Cliem , vol.274 , pp. 948-955
    • Hatada, S.1    Kuziel, W.2    Smithies, O.3    Maeda, N.4
  • 87
    • 0027422291 scopus 로고
    • Site-specific recombinases: Tools for genome engineering
    • KILBY NJ, SNAITII MR, MURRAY JAH: Site-specific recombinases: Tools for genome engineering. Trends Genet 9:413-421, 1994
    • (1994) Trends Genet , vol.9 , pp. 413-421
    • Kilby, N.J.1    Snaitii, M.R.2    Jah, M.3
  • 89
    • 0028059099 scopus 로고
    • Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting
    • Gu H, MARTII JD,ORBAN PC, MOSSMAN H, RAJEWSKY K: Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting. Science 265:103-106, 1994
    • (1994) Science , vol.265 , pp. 103-106
    • Gu, H.1    Martii, J.D.2    Orban, P.C.3    Mossman, H.4    Rajewsky, K.5
  • 90
    • 0030425881 scopus 로고    scopus 로고
    • Conditional mutagenesis in mice: The Cre/loxP recombination system. 1m
    • PLUCK A: Conditional mutagenesis in mice: The Cre/loxP recombination system. 1m J Exp Patlwl 77:269-278, 1996
    • (1996) J Exp Patlwl , vol.77 , pp. 269-278
    • Pluck, A.1
  • 92
    • 0029865151 scopus 로고    scopus 로고
    • Ecdysonc-inducible gene expression in mammalian cells and transcenic mice
    • No D, YAOTP, EVANS RM: Ecdysonc-inducible gene expression in mammalian cells and transcenic mice. Proc NatlAcad Sei USA 93:3346-3351, 1996
    • (1996) Proc NatlAcad Sei USA , vol.93 , pp. 3346-3351
    • No, D.1    Evans, R.M.2
  • 95
    • 0032481124 scopus 로고    scopus 로고
    • Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase
    • DANIELIAN PS, MUCCINO D, ROWITCII DH, MICHAEL SK, McMAHON AP: Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase. Cnrr Biol 8:1323-1326, 1998
    • (1998) Cnrr Biol , vol.8 , pp. 1323-1326
    • Danielian, P.S.1    Muccino, D.2    Rowitcii, D.H.3    Michael, S.K.4    McMahon, A.P.5
  • 96
    • 0029836033 scopus 로고    scopus 로고
    • Characterization of the rat NHE3 promoter
    • CANO A: Characterization of the rat NHE3 promoter. Am J Pltys/o/271:F629-F636, 1996
    • (1996) Am J Pltys/o , vol.271
    • Cano, A.1
  • 98
    • 0030985971 scopus 로고    scopus 로고
    • A 346-base pair region of the mouse gamma-glutamyl transpeptidase type II promoter contains sufficient cis-acting elements for kidney-restricted expression in transgenic mice
    • SEPULVEDA AR, HUANG SL, LEBOVITZ RM, LIEBER.MAN MW: A 346-base pair region of the mouse gamma-glutamyl transpeptidase type II promoter contains sufficient cis-acting elements for kidney-restricted expression in transgenic mice. J Biol Chem 272:11959-11967, 1997
    • (1997) J Biol Chem , vol.272 , pp. 11959-11967
    • Sepulveda, A.R.1    Huang, S.L.2    Lebovitz, R.M.3    Lieber.man, M.W.4
  • 99
    • 0029919180 scopus 로고    scopus 로고
    • Cloning and kidney cell-specific activity of the promoter of the murine renal Na-KCl cotransporter gene.
    • IGARASHI P, WIIYTE DA, Li K, NAGAMI GT: Cloning and kidney cell-specific activity of the promoter of the murine renal Na-KCl cotransporter gene. / Biol Chem 271:9666-9674, 1996
    • (1996) Biol Chem , vol.271 , pp. 9666-9674
    • Igarashi, P.1    Wiiyte, D.A.2    Li, K.3    Nagami, G.T.4
  • 100
    • 0028819686 scopus 로고
    • DARPP-32 promoter directs transgene expression to renal thick ascending limb of loop of Henle
    • BLAU S, DALY L, FIENBERG A, TEITELMAN G, EHRLICH ME: DARPP-32 promoter directs transgene expression to renal thick ascending limb of loop of Henle. Am J Physiol 269:F564-F570, 1995
    • (1995) Am J Physiol , vol.269
    • Blau, S.1    Daly, L.2    Fienberg, A.3    Teitelman, G.4    Ehrlich, M.E.5
  • 101
    • 0032925933 scopus 로고    scopus 로고
    • Targeting collecting tubules using the aquaporin-2 promoter
    • STRICKLETT PK, NELSON RD, KOIIAN DE: Targeting collecting tubules using the aquaporin-2 promoter. Exp Nephrol 7:67-74, 1999
    • (1999) Exp Nephrol , vol.7 , pp. 67-74
    • Stricklett, P.K.1    Nelson, R.D.2
  • 102
    • 0029988266 scopus 로고    scopus 로고
    • Identification of the proximal erythroid promoter region of the mouse anion exchanger gene
    • SAUR KE, DANIELS BP, HANSPAL M: Identification of the proximal erythroid promoter region of the mouse anion exchanger gene. Blood 88:4500-4509, 1996
    • (1996) Blood , vol.88 , pp. 4500-4509
    • Saur, K.E.1    Daniels, B.P.2    Hanspal, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.