Complementation of reduced survival, hypotension, and renal abnormalities in angiotensinogen-deficient mice by the human renin and human angiotensinogen genes

Journal of Clinical Investigation

Volumn 99, Issue 6, 1997, Pages 1258-1264

  Davisson, Robin L ^a   Kim, Hyung Suk ^b   Krege, John H ^b   Lager, Donna J ^a   Smithies, Oliver ^b   Sigmund, Curt D ^a  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

gene targeting; genetics; hypertension; renin angiotensin system; transgenic animals

Indexed keywords

ANGIOTENSINOGEN; RENIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE NUMBER; GENETIC COMPLEMENTATION; HYPOTENSION; KIDNEY DISEASE; LYMPHOCYTIC INFILTRATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SURVIVAL; TRANSGENIC MOUSE;

EID: 0030952323     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119283     Document Type: Article

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