메뉴 건너뛰기




Volumn 1999, Issue 1, 1999, Pages 3-9

Novel mechanism of hypertension revealed by cell-specific targeting of human angiotensinogen in transgenic mice

Author keywords

Angiotensin II; Blood pressure regulation; Renal function; Transgenic mice

Indexed keywords

MUS MUSCULUS;

EID: 0033564984     PISSN: 15312267     EISSN: None     Source Type: Journal    
DOI: 10.1152/physiolgenomics.1999.1.1.3     Document Type: Article
Times cited : (109)

References (31)
  • 1
    • 0027157347 scopus 로고
    • Proximal tubular secretion of angiotensin II in rats
    • Renal Fluid Electrolyte Physiol. 33
    • Braam, B., K. D. Mitchell, J. Fox, and L. G. Navar. Proximal tubular secretion of angiotensin II in rats. Am. J. Physiol. 264 (Renal Fluid Electrolyte Physiol. 33): F891-F898, 1993.
    • (1993) Am. J. Physiol. , vol.264
    • Braam, B.1    Mitchell, K.D.2    Fox, J.3    Navar, L.G.4
  • 2
    • 0001989107 scopus 로고
    • Oral angiotensin-converting enzyme inhibitor in long-term treatment of hypertensive patients
    • Brunner, H. R., H. Gavras, and A. Waeber. Oral angiotensin-converting enzyme inhibitor in long-term treatment of hypertensive patients. Ann. Intern. Med. 2: 1317-1325, 1979.
    • (1979) Ann. Intern. Med. , vol.2 , pp. 1317-1325
    • Brunner, H.R.1    Gavras, H.2    Waeber, A.3
  • 3
    • 0025236941 scopus 로고
    • Angiotensin II: A powerful controller of sodium transport in the early proximal tubule
    • Cogan, M. G. Angiotensin II: a powerful controller of sodium transport in the early proximal tubule. Hypertension 15: 451-458, 1990.
    • (1990) Hypertension , vol.15 , pp. 451-458
    • Cogan, M.G.1
  • 4
    • 0030004732 scopus 로고    scopus 로고
    • The role of the kidney in hypertension
    • Cowley, A. W. J., and R. J. Roman. The role of the kidney in hypertension. JAMA 275: 1581-1589, 1996.
    • (1996) JAMA , vol.275 , pp. 1581-1589
    • Cowley, A.W.J.1    Roman, R.J.2
  • 5
    • 0032538972 scopus 로고    scopus 로고
    • The brain renin-angiotensin system contributes to the hypertension exhibited by mice containing both human renin and human angiotensinogen transgenes
    • Davisson, R. L., G. Yang, T. G. Beltz, M. D. Cassell, A. K. Johnson, and C. D. Sigmund. The brain renin-angiotensin system contributes to the hypertension exhibited by mice containing both human renin and human angiotensinogen transgenes. Circ. Res. 83: 1047-1058, 1998.
    • (1998) Circ. Res. , vol.83 , pp. 1047-1058
    • Davisson, R.L.1    Yang, G.2    Beltz, T.G.3    Cassell, M.D.4    Johnson, A.K.5    Sigmund, C.D.6
  • 6
    • 0030736087 scopus 로고    scopus 로고
    • The kidney androgen-regulated protein (KAP) promoter confers renal proximal tubule cell-specific and highly androgen-responsive expression on the human angiotensinogen gene in transgenic mice
    • Ding, Y., R. L. Davisson, D. O. Hardy, L.-J. Zhu, D. C. Merrill, J. F. Catterall, and C. D. Sigmund. The kidney androgen-regulated protein (KAP) promoter confers renal proximal tubule cell-specific and highly androgen-responsive expression on the human angiotensinogen gene in transgenic mice. J. Biol. Chem. 272: 28142-28148, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 28142-28148
    • Ding, Y.1    Davisson, R.L.2    Hardy, D.O.3    Zhu, L.-J.4    Merrill, D.C.5    Catterall, J.F.6    Sigmund, C.D.7
  • 7
    • 0025184049 scopus 로고
    • Signaling mechanisms coupled to the angiotensin receptor of proximal tubular epithelium
    • Douglas, J. G., M. Romero, and U. Hopfer. Signaling mechanisms coupled to the angiotensin receptor of proximal tubular epithelium. Kidney Int. 30: S43-S47, 1990.
    • (1990) Kidney Int. , vol.30
    • Douglas, J.G.1    Romero, M.2    Hopfer, U.3
  • 8
    • 0023922776 scopus 로고
    • Circulating versus local renin-angiotensin system in cardiovascular homeostasis
    • Dzau, V. J. Circulating versus local renin-angiotensin system in cardiovascular homeostasis. Circulation 77: I4-I13, 1988.
    • (1988) Circulation , vol.77
    • Dzau, V.J.1
  • 9
    • 0027190950 scopus 로고
    • Chimeric renin-angiotensin system demonstrates sustained increase in blood pressure of transgenic mice carrying both human renin and human angiotensinogen genes
    • Fukamizu, A., K Sugimura, E. Takimoto, F. Sugiyama, M.-S. Seo, S. Takahashi, T. Hatae, N. Kajiwara, K. Yagami, and K. Murakami. Chimeric renin-angiotensin system demonstrates sustained increase in blood pressure of transgenic mice carrying both human renin and human angiotensinogen genes. J. Biol. Chem. 268: 11617-11621, 1993.
    • (1993) J. Biol. Chem. , vol.268 , pp. 11617-11621
    • Fukamizu, A.1    Sugimura, K.2    Takimoto, E.3    Sugiyama, F.4    Seo, M.-S.5    Takahashi, S.6    Hatae, T.7    Kajiwara, N.8    Yagami, K.9    Murakami, K.10
  • 11
    • 0028301777 scopus 로고
    • Comparative studies on species-specific reactivity between renin and angiotensinogen
    • Hatae, T., E. Takimoto, K. Murakami, and A. Fukamizu. Comparative studies on species-specific reactivity between renin and angiotensinogen. Mol. Cell. Biochem. 131: 43-47, 1994.
    • (1994) Mol. Cell. Biochem. , vol.131 , pp. 43-47
    • Hatae, T.1    Takimoto, E.2    Murakami, K.3    Fukamizu, A.4
  • 13
    • 0025056511 scopus 로고
    • In situ hybridization evidence for angiotensinogen messenger RNA in the rat proximal tubule. An hypothesis for the intrarenal renin angiotensin system
    • Ingelfinger, J. R., W. M. Zuo, E. A. Fon, K. E. Ellison, and V. J. Dzau. In situ hybridization evidence for angiotensinogen messenger RNA in the rat proximal tubule. An hypothesis for the intrarenal renin angiotensin system. J. Clin. Invest. 85: 417-423, 1990.
    • (1990) J. Clin. Invest. , vol.85 , pp. 417-423
    • Ingelfinger, J.R.1    Zuo, W.M.2    Fon, E.A.3    Ellison, K.E.4    Dzau, V.J.5
  • 16
    • 0029810060 scopus 로고    scopus 로고
    • Comparative cardiovascular effects of the angiotensin II type 1 receptor antagonists ZD 7155 and losartan in the rat
    • Junggren, I. L., X. Zhao, X. Sun, and T. Hedner. Comparative cardiovascular effects of the angiotensin II type 1 receptor antagonists ZD 7155 and losartan in the rat. J. Pharm. Pharmacol. 48: 829-833, 1996.
    • (1996) J. Pharm. Pharmacol. , vol.48 , pp. 829-833
    • Junggren, I.L.1    Zhao, X.2    Sun, X.3    Hedner, T.4
  • 17
    • 0019723176 scopus 로고
    • Role of the intrarenal renin-angiotensin system in the control of renal function
    • Levens, N. R., M. J. Peach, and R. M. Carey. Role of the intrarenal renin-angiotensin system in the control of renal function. Circ. Res. 48: 157-167, 1981.
    • (1981) Circ. Res. , vol.48 , pp. 157-167
    • Levens, N.R.1    Peach, M.J.2    Carey, R.M.3
  • 18
    • 0030049446 scopus 로고    scopus 로고
    • Chronic hypertension and altered baroreflex responses in transgenic mice containing the human renin and human angiotensinogen genes
    • Merrill, D. C., M. W. Thompson, C. Carney, G. Schlager, J. E. Robillard, and C. D. Sigmund. Chronic hypertension and altered baroreflex responses in transgenic mice containing the human renin and human angiotensinogen genes. J. Clin. Invest. 97: 1047-1055, 1996.
    • (1996) J. Clin. Invest. , vol.97 , pp. 1047-1055
    • Merrill, D.C.1    Thompson, M.W.2    Carney, C.3    Schlager, G.4    Robillard, J.E.5    Sigmund, C.D.6
  • 19
    • 0023386760 scopus 로고
    • Androgen regulated expression of kidney androgen-regulated protein mRNAis localized in the epithelial cells of the murine renal proximal convoluted tubules
    • Meseguer, A., and J. F. Catterall. Androgen regulated expression of kidney androgen-regulated protein mRNAis localized in the epithelial cells of the murine renal proximal convoluted tubules. Mol. Endocrinol. 1: 535-541, 1987.
    • (1987) Mol. Endocrinol. , vol.1 , pp. 535-541
    • Meseguer, A.1    Catterall, J.F.2
  • 20
    • 0025096120 scopus 로고
    • Cell-specific expression of kidney androgen-regulated protein messenger RNA is under multihormonal control
    • Meseguer, A., and J. F. Catterall. Cell-specific expression of kidney androgen-regulated protein messenger RNA is under multihormonal control. Mol. Endocrinol. 4: 1240-1248, 1990.
    • (1990) Mol. Endocrinol. , vol.4 , pp. 1240-1248
    • Meseguer, A.1    Catterall, J.F.2
  • 21
    • 0030867545 scopus 로고    scopus 로고
    • Angiotensinogen T235 expression is elevated in decidual spiral arteries
    • Morgan, T., C. Craven, L. Nelson, J. M. Lalouel, and K. Ward. Angiotensinogen T235 expression is elevated in decidual spiral arteries. J. Clin. Invest. 100: 1406-1415, 1997.
    • (1997) J. Clin. Invest. , vol.100 , pp. 1406-1415
    • Morgan, T.1    Craven, C.2    Nelson, L.3    Lalouel, J.M.4    Ward, K.5
  • 22
    • 0030885195 scopus 로고    scopus 로고
    • Intrarenal production of angiotensin II
    • Navar, L. G., J. D. Imig, and C. T. Wang. Intrarenal production of angiotensin II. Semin. Nephrol. 17: 412-422, 1997.
    • (1997) Semin. Nephrol. , vol.17 , pp. 412-422
    • Navar, L.G.1    Imig, J.D.2    Wang, C.T.3
  • 23
    • 0021982860 scopus 로고
    • Correction of abnormal renal blood flow response to angiotensin II by converting enzyme inhibition in essential hypertensives
    • Redgrave, J., S. Rabinowe, N. K. Hollenberg, and G. H. Williams. Correction of abnormal renal blood flow response to angiotensin II by converting enzyme inhibition in essential hypertensives. J. Clin. Invest. 75: 1285-1290, 1985.
    • (1985) J. Clin. Invest. , vol.75 , pp. 1285-1290
    • Redgrave, J.1    Rabinowe, S.2    Hollenberg, N.K.3    Williams, G.H.4
  • 24
    • 0025279257 scopus 로고
    • + exchange in proximal tubule cells
    • Renal Fluid Electrolyte Physiol. 27
    • + exchange in proximal tubule cells. Am. J. Physiol. 258 (Renal Fluid Electrolyte Physiol. 27): F1188-F1195, 1990.
    • (1990) Am. J. Physiol. , vol.258
    • Saccomani, G.1    Mitchell, K.D.2    Navar, L.G.3
  • 25
    • 0026463585 scopus 로고
    • Evidence for tissue-specific activation of renal angiotensinogen mRNA expression in chronic stable experimental heart failure
    • Schunkert, H., J. R. Ingelfinger, A. T. Hirsch, S. S. Tang, S. E. Litwin, C. E. Talsness, and V. J. Dzau. Evidence for tissue-specific activation of renal angiotensinogen mRNA expression in chronic stable experimental heart failure. J. Clin. Invest. 90: 1523-1529, 1992.
    • (1992) J. Clin. Invest. , vol.90 , pp. 1523-1529
    • Schunkert, H.1    Ingelfinger, J.R.2    Hirsch, A.T.3    Tang, S.S.4    Litwin, S.E.5    Talsness, C.E.6    Dzau, V.J.7
  • 27
    • 0026514648 scopus 로고
    • Regulated tissue- and cell-specific expression of the human renin gene in transgenic mice
    • Sigmund, C. D., C. A. Jones, C. M. Kane, C. Wu, J. A. Lang, and K. W. Gross. Regulated tissue- and cell-specific expression of the human renin gene in transgenic mice. Circ. Res. 70: 1070-1079, 1992.
    • (1992) Circ. Res. , vol.70 , pp. 1070-1079
    • Sigmund, C.D.1    Jones, C.A.2    Kane, C.M.3    Wu, C.4    Lang, J.A.5    Gross, K.W.6
  • 29
    • 0025373857 scopus 로고
    • Combined intrarenal blockade of the renin-angiotensin system in the conscious dog
    • Renal Fluid Electrolyte Physiol. 27
    • Siragy, H. M., N. L. Howell, M. J. Peach, and R. M. Carey. Combined intrarenal blockade of the renin-angiotensin system in the conscious dog. Am. J. Physiol. 258 (Renal Fluid Electrolyte Physiol. 27): F522-F529,1990.
    • (1990) Am. J. Physiol. , vol.258
    • Siragy, H.M.1    Howell, N.L.2    Peach, M.J.3    Carey, R.M.4
  • 31
    • 0028608104 scopus 로고
    • Functional expression of the human angiotensinogen gene in transgenic mice
    • Yang, G., D. C. Merrill, M. W. Thompson, J. E. Robillard, and C. D. Sigmund. Functional expression of the human angiotensinogen gene in transgenic mice. J. Biol. Chem. 269: 32497-32502, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 32497-32502
    • Yang, G.1    Merrill, D.C.2    Thompson, M.W.3    Robillard, J.E.4    Sigmund, C.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.