Targeting deletion of angiotensin type 1B receptor gene in the mouse

American Journal of Physiology - Renal Physiology

Volumn 272, Issue 3 41-3, 1997, Pages

  Chen, Xiangmei ^a   Li, Wenge ^a   Yoshida, Hiroaki ^a   Tsuchida, Shinya ^a   Nishimura, Hideki ^a   Takemoto, Fumi ^a   Okubo, Soichiro ^a   Fogo, Agnes ^a   Matsusaka, Taiji ^a   Ichikawa, Iekuni ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Aldosterone; Blood pressure; Gene knock out; Hypertension; Kidney

Indexed keywords

ANGIOTENSIN RECEPTOR;

ANIMAL EXPERIMENT; ARTERIAL PRESSURE; ARTICLE; BLOOD PRESSURE REGULATION; GENE DELETION; GENE TARGETING; HORMONAL REGULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DENSITY; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; REPORTER GENE; TISSUE DISTRIBUTION; TRANSCRIPTION REGULATION;

EID: 0000264140     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.1997.272.3.f299     Document Type: Article

References (39)

1. Burson, J. M., G. Aguilera, K. W. Gross, and C. D. Sigmund. Differential expression of angiotensin receptor 1A and 1B in mouse. Am. J. Physiol. 267 (Endocrinol. Metab. 30): E260-E267, 1994.
2. Chiu, A. T., W. F. Herblin, D. E. McCall, R. J. Ardecky, D. J. Carini, J. V. Duncia, L. J. Pease, P. C. Wong, R. R. Wexler, A. L. Johnson, and P. B. Timmermans. Identification of angiotensin II receptor subtypes. Biochem. Biophys. Res. Commun. 165: 196-203, 1989.
3. Clark A. J., T. Balla, M. R. Jones, and K. J. Catt. Stimulation of early gene expression by angiotensin II in bovine adrenal glomerulosa cells: roles of calcium and protein kinase C. Mol. Endocrinol. 6: 1889-1898, 1992.
4. Clauser E., C. Bihoreau, C. Monnot, B. Teutsch, S. Conchon, E. Davies, and P. Corvol. Is angiotensin II a growth factor? Diabetes Metab. 18: 129-136, 1992.
5. Esther, C. R., Jr., T. E. Howard, E. M. Marino, J. M. Goddard, M. R. Capecchi, and K. E. Bernstein. Mice lacking angiotensin-converting enzyme have low blood pressure, renal pathology, and reduced male fertility. Lab. Invest. 74: 953-965, 1996.
6. Gasc, J. M., S. Shanmugam, M. Sibony, and P. Corvol. Tissue-specific expression of type 1 angiotensin II receptor subtypes: an in situ hybridization study. Hypertension 24: 531-537, 1994.
7. Gill G. N., C. R. Ill, and M. H. Simonian. Angiotensin stimulation of bovine adrenocortical cell growth. Proc. Natl. Acad. Sci. USA 74: 5569-5573, 1977.
8. Gomez, R. A., A. C. Pupilli, and A. D. Everett. Molecular and cellular aspects of renin during kidney ontogeny. Pediatr. Nephrol. 5: 80-87, 1991.
9. Healy, D. P., M. Q. Ye, and M. Troyanovskaya. Localization of angiotensin II type 1 receptor subtype mRNA in rat kidney. Am. J. Physiol. 268 (Renal Fluid Electrolyte Physiol. 37): F220-F226, 1995.
10. Hein, L., G. S. Barsh, R. E. Pratt, V. J. Dzau, and B. K. Kobilka. Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor in mice. Nature 377: 744-747, 1995.
11. Hogan, B., R. Beddington, F. Costantini, and E. Lacy. Manipulating the Mouse Embryo (2nd ed.). Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 1994.
12. Hooper, M., K. Hardy, A. Handyside, S. Hunter, and M. Monk. HPRT-deficient (Lesh-Nyhan) mouse embryos derived from germline colonization by cultured cells. Nature 326: 292-295, 1987.
13. Huckle W. R., and H. S. Earp. Regulation of cell proliferation and growth by angiotensin II. Prog. Growth Factor Res. 5: 177-194, 1994.
14. Ichikawa, I., and R. C. Harris. Angiotensin actions in the kidney: renewed insight into the old hormone. Kidney Int. 40: 583-596, 1991.
15. Ichiki, T., P.A. Labosky, C. Shiota, S. Okuyama, Y. Imagawa, A. Fogo, F. Nirmura, I. Ichikawa, B. L. M. Hogan, and T. Inagami. Effects on blood pressure and exploratory behavior of mice lacking angiotensin II type 2 receptor. Nature 377: 748-750, 1995.
16. Ito, M., M. I. Oliverio, P. J. Mannon, C. F. Best, N. Maeda, O. Smithies, and T. M. Coffman. Regulation of blood pressure by the type 1A angiotensin II receptor gene. Proc. Natl. Acad. Sci. USA 92: 3521-3525, 1995.
17. Iwai, N., and T. Inagami. Identification of two subtypes in the rat type 1 angiotensin II receptor. FEBS Lett. 298: 257-260, 1992.
18. Kakar, S. S., K. K. Riel, and J. D. Neill. Differential expression of angiotensin II receptor subtype mRNAs (AT1A and AT1B) in the brain. Biochem. Biophys. Res. Commun. 185: 688-692, 1992.
19. Kakar, S. S., J. C. Sellers, D. C. Devor, L. C. Musgrove, and J. D. Neill. Angiotensin II type 1 receptor subtype cDNAs: differential tissue expression and hormonal regulation. Biochem. Biophys. Res. Commun. 183: 1090-1096, 1992.
20. Kakar, S. S., J. C. Sellers, L. C. Musgrove, and J. D. Neill. Angiotensin II type 1 receptor subtypes: cloning and expression (Abstract). FASEB J. 6: 1173, 1992.
21. Kaufman, R. J., M. V. Davies, L. C. Wasley, and D. Michnick. Improved vectors for stable expression of foreign genes in mammalian cells by use of the untranslated leader sequence from EMC virus. Nucleic Acids Res. 19: 4485-4490, 1991.
22. Kim, H. S., J. H. Krege, K. D. Kluchman, J. R. Hagaman, J. B. Hodgin, C. F. Best, J. C. Jennette, T. M. Coffman, N. Maeda, and O. Smithies. Genetic control of blood pressure and the angiotensinogen locus. Proc. Natl. Acad. Sci. USA 92: 2735-2739, 1995.
23. Kitami, Y., T. Okura, K. Marumoto, R. Wakamiya, and, K. Hiwada. Differential gene expression and regulation of type 1 angiotensin II receptor subtypes in the rat. Biochem. Biophys. Res. Commun. 188: 446-452, 1992.
24. Krege, J. H., S. W. M. John, L. L. Langenbach, J. B. Hodgin, J. R. Hagaman, E. S. Bachman, J. C. Jennette, D. A. O'Brien, and O. Smithies. Male-female differences in fertility and blood pressure in ACE-deficient mice. Nature 375: 146-148, 1995.
25. Llorens-Cortes, C., B. Greenberg, H. Huang, and P. Corvol. Tissular expression and regulation of type 1 angiotensin II receptor subtypes by quantitative reverse transcriptase-polymerase chain reaction analysis. Hypertension. 24: 538-548, 1994.
26. Matsusaka, T., H. Nishimura, H. Utsunomiya, J. Kakuchi, F. Niimura, T. Inagami, A. Fogo, and I. Ichikawa. Chimeric mice carrying 'regional' targeted deletion of the angiotensin type 1A receptor gene: evidence against the role for local angiotensin in the in vivo feedback regulation of renin synthesis in juxtaglomerular cells. J. Clin. Invest. 98: 1867-1877, 1996.
27. Murphy, T. J., K. Takeuchi, and R. W. Alexander. Molecular cloning of AT1 angiotensin receptors. Am. J. Hypertens. 5: 236-242, 1992.
28. Natarajan, R., N. Gonzales, P. J. Hornsby, and J. Nadler. Mechanism of angiotensin II-induced proliferation in bovine adrenocortical cells. Endocrinology 131: 1174-1180, 1992.
29. Niimura, F., P. A. Labosky, J. Kakuchi, S. Okubo, H. Yoshida, T. Oikawa, T. Ichiki, A. J. Naftilan, A. Fogo, T. Inagami, B. L. M. Hogan, and I. Ichikawa. Gene targeting in mice reveals a requirement for angiotensin in the development and maintenance of kidney morphology and growth foctor regulation. J. Clin. Invest. 96: 2947-2954, 1995.
30. Nishimura, H., T. Matsusaka, H. Utsunomiya, A. Fogo, V. Kon, T. Inagami, and I. Ichikawa. Gene targeting reveals that angiotensin type 2 receptor is not essential for embryonic development of the kidney (Abstract). J. Am. Soc. Nephrol. In press.
31. Okubo, S., H. Nishimura, T. Matsusaka, F. Takemoto, A. Fogo, and I. Ichikawa. Evidence from angiotensinogen knock out (Atg-KO) mice that a potent angiotensin-independent mechanism exists for the secondary hyperaldosteronism during dietary salt restriction (Abstract). J. Am. Soc. Nephrol. In press.
32. Penhoat, A., P. Leduque, C. Jaillard, P. G. Chatelain, P. M. Dubois, and J. M. Saez. ACTH and angiotensin II regulation of insulin-like growth factor-I and its binding proteins in cultured bovine adrenal cells. J. Mol. Endocrinol. 7: 223-232, 1991.
33. Remirez-Solis, R., A. C. Davis, and A. Bradley. Gene targeting in embryonic stem cells. Methods Enzymol. 225: 855-878, 1993.
34. Sasamura, H., L. Hein, J. E. Krieger, R. E. Pratt, B. K. Kobilka, and V. J. Dzau. Cloning, characterization, and expression of two angiotensin receptor (AT1) isoforms from the mouse genome. Bochem. Biophys. Res. Commun. 185: 253-259, 1992.
35. Shanmugam, S., P. Corvol, and J. M. Gasc. Ontogeny of the two angiotesin II receptor subtypes in rats. Am. J. Physiol. 267 (Endocrinol. Metab. 30): E828-E836, 1994.
36. Shanmugam, S., C. Monnot, P. Corvol, and J. M. Gasc. Distribution of type 1 angiotensin II receptor subtype messenger RNAs in the rat fetus. Hypertension 23: 137-141, 1994.
37. Sugaya, T., S. Nishimatsu, K. Tanimoto, E. Takimoto, T. Yamagishi, K. Imamura, S. Goto, K. Imaizumi, Y. Hisada, A. Ostuka, H. Uchida, M. Sugiura, K. Fukuta, A. Fukamizu, and K. Murakami. Angiotensin II type 1a receptor-deficient mice with hypotension and hyperrenimemia. J. Biol. Chem. 270: 18719-18722, 1995.
38. Tian, Y., T. Balla, A. J. Baukal, and K. J. Catt. Growth responses to angiotensin II in bovine adrenal glomerulosa cells. Am. J. Physiol. 268 (Endocrinol. Metab. 31): E135-E144, 1995.
39. Ye, M. Q., and D. P. Healy. Characterization of an angiotensin type 1 receptor partial cDNA from rat kidney: Evidence for a novel AT1B receptor subtype. Biochem. Biophys. Res. Commun. 185: 204-210, 1992.