메뉴 건너뛰기




Volumn 62, Issue 1, 2000, Pages 1-13

Prostaglandins and fatty acids regulate transcriptional signaling via the peroxisome proliferator activated receptor nuclear receptors

Author keywords

[No Author keywords available]

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; 4 [4 [3 (4 ACETYL 3 HYDROXY 2 PROPYLPHENOXY)PROPOXY]PHENOXY]ACETIC ACID; ANTIDIABETIC AGENT; CARBACYCLIN; CELL NUCLEUS RECEPTOR; INDOMETACIN; L 796449; N (2 BENZOYLPHENYL) O [2 (METHYL 2 PYRIDINYLAMINO)ETHYL]TYROSINE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PIOGLITAZONE; POLYUNSATURATED FATTY ACID; PROSTACYCLIN DERIVATIVE; PROSTAGLANDIN DERIVATIVE; RECEPTOR SUBTYPE; ROSIGLITAZONE; TROGLITAZONE; UNCLASSIFIED DRUG;

EID: 0033885498     PISSN: 00906980     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0090-6980(00)00071-X     Document Type: Review
Times cited : (58)

References (85)
  • 1
    • 0024558198 scopus 로고
    • The eicosanoids and their biochemical mechanisms of action
    • Smith W.L. The eicosanoids and their biochemical mechanisms of action. Biochem J. 259:1989;315-324.
    • (1989) Biochem J , vol.259 , pp. 315-324
    • Smith, W.L.1
  • 2
    • 0026761179 scopus 로고
    • Prostanoid biosynthesis and mechanisms of action
    • Smith W.L. Prostanoid biosynthesis and mechanisms of action. Am J Physiol. 263:1992;F181-F191.
    • (1992) Am J Physiol , vol.263 , pp. 181-F191
    • Smith, W.L.1
  • 3
    • 0023796962 scopus 로고
    • Occurrence of 9-deoxy-δ 9, delta 12-13,14-dihydroprostaglandin D2 in human urine
    • Hirata Y., Hayashi H., Ito S., et al. Occurrence of 9-deoxy-δ 9, delta 12-13,14-dihydroprostaglandin D2 in human urine. J Biol Chem. 263:1988;16619-16625.
    • (1988) J Biol Chem , vol.263 , pp. 16619-16625
    • Hirata, Y.1    Hayashi, H.2    Ito, S.3
  • 4
    • 0023031770 scopus 로고
    • Site and mechanism of growth inhibition by prostaglandins. II. Temperature-dependent transfer of a cyclopentenone prostaglandin to nuclei
    • Narumiya S., Ohno K., Fujiwara M., Fukushima M. Site and mechanism of growth inhibition by prostaglandins. II. Temperature-dependent transfer of a cyclopentenone prostaglandin to nuclei. J Pharmacol Exp Ther. 239:1986;506-511.
    • (1986) J Pharmacol Exp Ther , vol.239 , pp. 506-511
    • Narumiya, S.1    Ohno, K.2    Fujiwara, M.3    Fukushima, M.4
  • 5
    • 0023176538 scopus 로고
    • Site and mechanism of growth inhibition by prostaglandins. III. Distribution and binding of prostaglandin A2 and delta 12-prostaglandin J2 in nuclei
    • Narumiya S., Ohno K., Fukushima M., Fujiwara M. Site and mechanism of growth inhibition by prostaglandins. III. Distribution and binding of prostaglandin A2 and delta 12-prostaglandin J2 in nuclei. J Pharmacol Exp Ther. 242:1987;306-311.
    • (1987) J Pharmacol Exp Ther , vol.242 , pp. 306-311
    • Narumiya, S.1    Ohno, K.2    Fukushima, M.3    Fujiwara, M.4
  • 6
    • 0028972025 scopus 로고
    • 15-Deoxy-δ 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma
    • Forman B.M., Tontonoz P., Chen J., Brun R.P., Spiegelman B.M., Evans R.M. 15-Deoxy-δ 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Cell. 83:1995;803-812.
    • (1995) Cell , vol.83 , pp. 803-812
    • Forman, B.M.1    Tontonoz, P.2    Chen, J.3    Brun, R.P.4    Spiegelman, B.M.5    Evans, R.M.6
  • 7
    • 0028972026 scopus 로고
    • A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation
    • Kliewer S.A., Lenhard J.M., Willson T.M., Patel I., Morris D.C., Lehmann J.M. A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation. Cell. 83:1995;813-819.
    • (1995) Cell , vol.83 , pp. 813-819
    • Kliewer, S.A.1    Lenhard, J.M.2    Willson, T.M.3    Patel, I.4    Morris, D.C.5    Lehmann, J.M.6
  • 8
    • 0026754728 scopus 로고
    • Biological activities and mechanisms of action of PGJ2 and related compounds: An update
    • Fukushima M. Biological activities and mechanisms of action of PGJ2 and related compounds an update . Prostaglandins Leukotrienes Essent Fatty Acids. 47:1992;1-12.
    • (1992) Prostaglandins Leukotrienes Essent Fatty Acids , vol.47 , pp. 1-12
    • Fukushima, M.1
  • 9
    • 0024209566 scopus 로고
    • Induction of 68,000-dalton heat shock proteins by cyclopentenone prostaglandins. Its association with prostaglandin-induced G1 block in cell cycle progression
    • Ohno K., Fukushima M., Fujiwara M., Narumiya S. Induction of 68,000-dalton heat shock proteins by cyclopentenone prostaglandins. Its association with prostaglandin-induced G1 block in cell cycle progression. J Biol Chem. 263:1988;19764-19770.
    • (1988) J Biol Chem , vol.263 , pp. 19764-19770
    • Ohno, K.1    Fukushima, M.2    Fujiwara, M.3    Narumiya, S.4
  • 10
    • 0023575292 scopus 로고
    • Selective synthesis and retention of 66k protein in a human neuroblastoma cell line (NCG) treated with a cytotoxic dosage of delta 12-prostaglandin J2
    • Shimizu Y., Todo S., Imashuku S. Selective synthesis and retention of 66k protein in a human neuroblastoma cell line (NCG) treated with a cytotoxic dosage of delta 12-prostaglandin J2. Prostaglandins. 34:1987;769-781.
    • (1987) Prostaglandins , vol.34 , pp. 769-781
    • Shimizu, Y.1    Todo, S.2    Imashuku, S.3
  • 11
    • 0001065185 scopus 로고
    • Prostaglandins with antiproliferative activity induce the synthesis of a heat shock protein in human cells
    • Santoro M.G., Garaci E., Amici C. Prostaglandins with antiproliferative activity induce the synthesis of a heat shock protein in human cells. Proc Natl Acad Sci USA. 86:1989;8407-8411.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 8407-8411
    • Santoro, M.G.1    Garaci, E.2    Amici, C.3
  • 12
    • 0012473279 scopus 로고
    • The nuclear receptor superfamily: The second decade
    • Mangelsdorf D.J., Thummel C., Beato M., et al. The nuclear receptor superfamily the second decade . Cell. 83:1995;835-839.
    • (1995) Cell , vol.83 , pp. 835-839
    • Mangelsdorf, D.J.1    Thummel, C.2    Beato, M.3
  • 13
    • 0029562554 scopus 로고
    • The RXR heterodimers and orphan receptors
    • Mangelsdorf D.J., Evans R.M. The RXR heterodimers and orphan receptors. Cell. 83:1995;841-850.
    • (1995) Cell , vol.83 , pp. 841-850
    • Mangelsdorf, D.J.1    Evans, R.M.2
  • 14
    • 0023913120 scopus 로고
    • The steroid and thyroid hormone receptor superfamily
    • Evans R.M. The steroid and thyroid hormone receptor superfamily. Science. 240:1988;889-895.
    • (1988) Science , vol.240 , pp. 889-895
    • Evans, R.M.1
  • 15
    • 0023797380 scopus 로고
    • Nuclear receptors enhance our understanding of transcription regulation
    • Green S., Chambon P. Nuclear receptors enhance our understanding of transcription regulation. Trends Genet. 4:1988;309-314.
    • (1988) Trends Genet , vol.4 , pp. 309-314
    • Green, S.1    Chambon, P.2
  • 16
    • 0030768745 scopus 로고    scopus 로고
    • Steroid receptor coactivator-1 is a histone acetyltransferase
    • Spencer T.E., Jenster G., Burcin M.M., et al. Steroid receptor coactivator-1 is a histone acetyltransferase. Nature (London). 389:1997;194-198.
    • (1997) Nature (London) , vol.389 , pp. 194-198
    • Spencer, T.E.1    Jenster, G.2    Burcin, M.M.3
  • 17
    • 0029758906 scopus 로고    scopus 로고
    • Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex
    • Fondell J.D., Ge H., Roeder R.G. Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex. Proc Natl Acad Sci USA. 93:1996;8329-8333.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 8329-8333
    • Fondell, J.D.1    Ge, H.2    Roeder, R.G.3
  • 18
    • 0032525781 scopus 로고    scopus 로고
    • A novel protein complex that interacts with the vitamin D3 receptor in a ligand-dependent manner and enhances VDR transactivation in a cell- free system
    • Rachez C., Suldan Z., Ward J., et al. A novel protein complex that interacts with the vitamin D3 receptor in a ligand-dependent manner and enhances VDR transactivation in a cell- free system. Genes Dev. 12:1998;1787-1800.
    • (1998) Genes Dev , vol.12 , pp. 1787-1800
    • Rachez, C.1    Suldan, Z.2    Ward, J.3
  • 19
    • 0032564424 scopus 로고    scopus 로고
    • The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion
    • [published erratum appears USA Nov 24;
    • Yuan CX, Ito M, Fondell JD, Fu ZY, Roeder RG. The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion [published erratum appears in Proc Natl Acad Sci USA 1998 Nov 24;95:14584]. Proc Natl Acad Sci USA 1998; 95:7939-44.
    • (1998) In Proc Natl Acad Sci , vol.95 , pp. 14584
    • Yuan, C.X.1    Ito, M.2    Fondell, J.D.3    Fu, Z.Y.4    Roeder, R.G.5
  • 20
    • 0032493455 scopus 로고    scopus 로고
    • Yuan CX, Ito M, Fondell JD, Fu ZY, Roeder RG. The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion [published erratum appears in Proc Natl Acad Sci USA 1998 Nov 24;95:14584]. Proc Natl Acad Sci USA 1998; 95:7939-44.
    • (1998) Proc Natl Acad Sci , vol.95 , pp. 7939-7944
  • 21
    • 0023857147 scopus 로고
    • Identification of a new class of steroid hormone receptors
    • Giguere V., Yang N., Segui P., Evans R.M. Identification of a new class of steroid hormone receptors. Nature (London). 331:1988;91-94.
    • (1988) Nature (London) , vol.331 , pp. 91-94
    • Giguere, V.1    Yang, N.2    Segui, P.3    Evans, R.M.4
  • 22
    • 0023712331 scopus 로고
    • The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function
    • Webster N.J., Green S., Jin J.R., Chambon P. The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function. Cell. 54:1988;199-207.
    • (1988) Cell , vol.54 , pp. 199-207
    • Webster, N.J.1    Green, S.2    Jin, J.R.3    Chambon, P.4
  • 23
    • 0018751062 scopus 로고
    • Depletion of L-3,5,3′-triiodothyronine and L-thyroxine in euthyroid calf serum for use in cell culture studies of the action of thyroid hormone
    • Samuels H.H., Stanley F., Casanova J. Depletion of L-3,5,3′-triiodothyronine and L-thyroxine in euthyroid calf serum for use in cell culture studies of the action of thyroid hormone. Endocrinology. 105:1979;80-85.
    • (1979) Endocrinology , vol.105 , pp. 80-85
    • Samuels, H.H.1    Stanley, F.2    Casanova, J.3
  • 24
    • 0022929864 scopus 로고
    • Stimulation of facilitated [3H]uridine transport by thyroid hormone in GH1 cells. Evidence for regulation by the thyroid hormone nuclear receptor
    • Stanley F., Tsai J.S., Samuels H.H. Stimulation of facilitated [3H]uridine transport by thyroid hormone in GH1 cells. Evidence for regulation by the thyroid hormone nuclear receptor. J Biol Chem. 261:1986;9400-9404.
    • (1986) J Biol Chem , vol.261 , pp. 9400-9404
    • Stanley, F.1    Tsai, J.S.2    Samuels, H.H.3
  • 25
    • 0030952937 scopus 로고    scopus 로고
    • Hypolipidemic drugs, polyunsaturated fatty acids and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ
    • Forman B.M., Chen J., Evans R.M. Hypolipidemic drugs, polyunsaturated fatty acids and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ Proc Natl Acad Sci USA. 94:1997;4312-4317.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4312-4317
    • Forman, B.M.1    Chen, J.2    Evans, R.M.3
  • 26
    • 0030985318 scopus 로고    scopus 로고
    • Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay
    • Krey G., Braissant O., L'Horset F., et al. Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay. Mol Endocrinol. 11:1997;779-791.
    • (1997) Mol Endocrinol , vol.11 , pp. 779-791
    • Krey, G.1    Braissant, O.2    L'Horset, F.3
  • 27
    • 0013854955 scopus 로고
    • Nature of the hepatomegalic effect produced by ethyl-chlorophenoxy-isobutyrate in the rat
    • Hess R., Staubli W., Riess W. Nature of the hepatomegalic effect produced by ethyl-chlorophenoxy-isobutyrate in the rat. Nature (London). 208:1965;856-858.
    • (1965) Nature (London) , vol.208 , pp. 856-858
    • Hess, R.1    Staubli, W.2    Riess, W.3
  • 28
    • 0030468075 scopus 로고    scopus 로고
    • Structural diversity of peroxisome proliferators and their effects on mammalian liver cells in vivo
    • de la Iglesia F., McGuire E.J., Haskins J.R., Lalwani N.D. Structural diversity of peroxisome proliferators and their effects on mammalian liver cells in vivo. Ann N Y Acad Sci. 804:1996;310-327.
    • (1996) Ann N Y Acad Sci , vol.804 , pp. 310-327
    • De La Iglesia, F.1    McGuire, E.J.2    Haskins, J.R.3    Lalwani, N.D.4
  • 29
    • 0025132245 scopus 로고
    • Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
    • Issemann I., Green S. Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature (London). 347:1990;645-650.
    • (1990) Nature (London) , vol.347 , pp. 645-650
    • Issemann, I.1    Green, S.2
  • 30
    • 0026517010 scopus 로고
    • Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors
    • Dreyer C., Krey G., Keller H., Givel F., Helftenbein G., Wahli W. Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors. Cell. 68:1992;879-887.
    • (1992) Cell , vol.68 , pp. 879-887
    • Dreyer, C.1    Krey, G.2    Keller, H.3    Givel, F.4    Helftenbein, G.5    Wahli, W.6
  • 31
    • 0028321529 scopus 로고
    • Differential expression and activation of a family of murine peroxisome proliferator-activated receptors
    • Kliewer S.A., Forman B.M., Blumberg B., et al. Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. Proc Natl Acad Sci USA. 91:1994;7355-7359.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7355-7359
    • Kliewer, S.A.1    Forman, B.M.2    Blumberg, B.3
  • 32
    • 0027749599 scopus 로고
    • Cloning of a new member of the peroxisome proliferator-activated receptor gene family from mouse liver
    • Zhu Y., Alvares K., Huang Q., Rao M.S., Reddy J.K. Cloning of a new member of the peroxisome proliferator-activated receptor gene family from mouse liver. J Biol Chem. 268:1993;26817-26820.
    • (1993) J Biol Chem , vol.268 , pp. 26817-26820
    • Zhu, Y.1    Alvares, K.2    Huang, Q.3    Rao, M.S.4    Reddy, J.K.5
  • 33
    • 0027504874 scopus 로고
    • Identification of two mPPAR related receptors and evidence for the existence of five subfamily members
    • Chen F., Law S.W., O'Malley B.W. Identification of two mPPAR related receptors and evidence for the existence of five subfamily members. Biochem Biophys Res Commun. 196:1993;671-677.
    • (1993) Biochem Biophys Res Commun , vol.196 , pp. 671-677
    • Chen, F.1    Law, S.W.2    O'Malley, B.W.3
  • 34
    • 0028641559 scopus 로고
    • Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor
    • Tontonoz P., Hu E., Spiegelman B.M. Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor. Cell. 79:1994;1147-1156.
    • (1994) Cell , vol.79 , pp. 1147-1156
    • Tontonoz, P.1    Hu, E.2    Spiegelman, B.M.3
  • 35
    • 0026785388 scopus 로고
    • Identification of a new member of the steroid hormone receptor superfamily that is activated by a peroxisome proliferator and fatty acids
    • Schmidt A., Endo N., Rutledge S.J., Vogel R., Shinar D., Rodan G.A. Identification of a new member of the steroid hormone receptor superfamily that is activated by a peroxisome proliferator and fatty acids. Mol Endocrinol. 6:1992;1634-1641.
    • (1992) Mol Endocrinol , vol.6 , pp. 1634-1641
    • Schmidt, A.1    Endo, N.2    Rutledge, S.J.3    Vogel, R.4    Shinar, D.5    Rodan, G.A.6
  • 36
    • 0026705751 scopus 로고
    • Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors
    • Kliewer S.A., Umesono K., Noonan D.J., Heyman R.A., Evans R.M. Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature (London). 358:1992;771-774.
    • (1992) Nature (London) , vol.358 , pp. 771-774
    • Kliewer, S.A.1    Umesono, K.2    Noonan, D.J.3    Heyman, R.A.4    Evans, R.M.5
  • 37
    • 0029066447 scopus 로고
    • Novel sequence determinants in peroxisome proliferator signaling
    • Palmer C.N.A., Hsu M.H., Griffin K.J., Johnson E.F. Novel sequence determinants in peroxisome proliferator signaling. J Biol Chem. 270:1995;16114-16121.
    • (1995) J Biol Chem , vol.270 , pp. 16114-16121
    • Palmer, C.N.A.1    Hsu, M.H.2    Griffin, K.J.3    Johnson, E.F.4
  • 38
    • 0029152375 scopus 로고
    • Isolation of the human peroxisome proliferator activated receptor gamma cDNA: Expression in hematopoietic cells and chromosomal mapping
    • Greene M.E., Blumberg B., McBride O.W., et al. Isolation of the human peroxisome proliferator activated receptor gamma cDNA expression in hematopoietic cells and chromosomal mapping . Gene Expr. 4:1995;281-299.
    • (1995) Gene Expr , vol.4 , pp. 281-299
    • Greene, M.E.1    Blumberg, B.2    McBride, O.W.3
  • 40
    • 0032540012 scopus 로고    scopus 로고
    • PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL
    • Tontonoz P., Nagy L., Alvarez J.G., Thomazy V.A., Evans R.M. PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell. 93:1998;241-252.
    • (1998) Cell , vol.93 , pp. 241-252
    • Tontonoz, P.1    Nagy, L.2    Alvarez, J.G.3    Thomazy, V.A.4    Evans, R.M.5
  • 42
    • 0030747895 scopus 로고    scopus 로고
    • Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-α In humans: No alteration in adipose tissue of obese and NIDDM patients
    • Auboeuf D., Rieusset J., Fajas L., et al. Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-α in humans no alteration in adipose tissue of obese and NIDDM patients . Diabetes. 46:1997;1319-1327.
    • (1997) Diabetes , vol.46 , pp. 1319-1327
    • Auboeuf, D.1    Rieusset, J.2    Fajas, L.3
  • 43
    • 0027525576 scopus 로고
    • The peroxisome proliferator-activated receptor:retinoid X receptor heterodimer is activated by fatty acids and fibrate hypolipidaemic drugs
    • Issemann I., Prince R.A., Tugwood J.D., Green S. The peroxisome proliferator-activated receptor:retinoid X receptor heterodimer is activated by fatty acids and fibrate hypolipidaemic drugs. J Mol Endocrinol. 11:1993;37-47.
    • (1993) J Mol Endocrinol , vol.11 , pp. 37-47
    • Issemann, I.1    Prince, R.A.2    Tugwood, J.D.3    Green, S.4
  • 44
    • 0006132932 scopus 로고    scopus 로고
    • Fatty acids and eicosanoids regulate gene expression through direct interactions with perxisome proliferator-activated receptors α and γ
    • Kliewer S.A., Sundseth S.S., Jones S.A., et al. Fatty acids and eicosanoids regulate gene expression through direct interactions with perxisome proliferator-activated receptors α and γ Proc Natl Acad Sci USA. 94:1997;4318-4323.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4318-4323
    • Kliewer, S.A.1    Sundseth, S.S.2    Jones, S.A.3
  • 45
    • 0028802627 scopus 로고
    • Differential activation of peroxisome proliferator-activated receptors by eicosanoids
    • Yu K., Bayona W., Kallen C.B., et al. Differential activation of peroxisome proliferator-activated receptors by eicosanoids. J Biol Chem. 270:1995;23975-23983.
    • (1995) J Biol Chem , vol.270 , pp. 23975-23983
    • Yu, K.1    Bayona, W.2    Kallen, C.B.3
  • 46
    • 0026045925 scopus 로고
    • Characterization of an 8-lipoxygenase activity induced by the phorbol ester tumor promoter 12-O-tetradecanoylphorbol-13-acetate in mouse skin in vivo
    • Furstenberger G., Hagedorn H., Jacobi T., et al. Characterization of an 8-lipoxygenase activity induced by the phorbol ester tumor promoter 12-O-tetradecanoylphorbol-13-acetate in mouse skin in vivo. J Biol Chem. 266:1991;15738-15745.
    • (1991) J Biol Chem , vol.266 , pp. 15738-15745
    • Furstenberger, G.1    Hagedorn, H.2    Jacobi, T.3
  • 47
    • 0026079030 scopus 로고
    • Investigation of the mechanism of biosynthesis of 8-hydroxyeicosatetraenoic acid in mouse skin
    • Hughes M.A., Brash A.R. Investigation of the mechanism of biosynthesis of 8-hydroxyeicosatetraenoic acid in mouse skin. Biochim Biophys Acta. 1081:1991;347-354.
    • (1991) Biochim Biophys Acta , vol.1081 , pp. 347-354
    • Hughes, M.A.1    Brash, A.R.2
  • 48
    • 0030827131 scopus 로고    scopus 로고
    • Molecular cloning and functional expression of a phorbol ester-inducible 8S-lipoxygenase from mouse skin
    • Jisaka M., Kim R.B., Boeglin W.E., Nanney L.B., Brash A.R. Molecular cloning and functional expression of a phorbol ester-inducible 8S-lipoxygenase from mouse skin. J Biol Chem. 272:1997;24410-24416.
    • (1997) J Biol Chem , vol.272 , pp. 24410-24416
    • Jisaka, M.1    Kim, R.B.2    Boeglin, W.E.3    Nanney, L.B.4    Brash, A.R.5
  • 50
    • 0031793850 scopus 로고    scopus 로고
    • A novel insulin sensitizer acts as a coligand for peroxisome proliferator-activated receptor-alpha (PPAR-alpha) and PPAR-gamma: Effect of PPAR-alpha activation on abnormal lipid metabolism in liver of Zucker fatty rats
    • Murakami K., Tobe K., Ide T., et al. A novel insulin sensitizer acts as a coligand for peroxisome proliferator-activated receptor-alpha (PPAR-alpha) and PPAR-gamma effect of PPAR-alpha activation on abnormal lipid metabolism in liver of Zucker fatty rats . Diabetes. 47:1998;1841-1847.
    • (1998) Diabetes , vol.47 , pp. 1841-1847
    • Murakami, K.1    Tobe, K.2    Ide, T.3
  • 51
    • 0033554001 scopus 로고    scopus 로고
    • Evidence for direct binding of fatty acids and eicosanoids to human peroxisome proliferators-activated receptor alpha
    • Murakami K., Ide T., Suzuki M., Mochizuki T., Kadowaki T. Evidence for direct binding of fatty acids and eicosanoids to human peroxisome proliferators-activated receptor alpha. Biochem Biophys Res Commun. 260:1999;609-613.
    • (1999) Biochem Biophys Res Commun , vol.260 , pp. 609-613
    • Murakami, K.1    Ide, T.2    Suzuki, M.3    Mochizuki, T.4    Kadowaki, T.5
  • 52
    • 0028997684 scopus 로고
    • Targeted disruption of the alpha Isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
    • Lee S.S.T., Pineau T., Drago J., et al. Targeted disruption of the alpha Isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol Cell Biol. 15:1995;3012-3022.
    • (1995) Mol Cell Biol , vol.15 , pp. 3012-3022
    • Lee, S.S.T.1    Pineau, T.2    Drago, J.3
  • 53
    • 0028988487 scopus 로고
    • PPAR gamma 2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene
    • Tontonoz P., Hu E., Devine J., Beale E.G., Spiegelman B.M. PPAR gamma 2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene. Mol Cell Biol. 15:1995;351-357.
    • (1995) Mol Cell Biol , vol.15 , pp. 351-357
    • Tontonoz, P.1    Hu, E.2    Devine, J.3    Beale, E.G.4    Spiegelman, B.M.5
  • 54
    • 0033137322 scopus 로고    scopus 로고
    • Prostaglandin J2 and 15-deoxy-δ12,14-prostaglandin J2 induce proliferation of cyclooxygenase-depleted colorectal cancer cells
    • Chinery R., Coffey R.J., Graves-Deal R., et al. Prostaglandin J2 and 15-deoxy-δ12,14-prostaglandin J2 induce proliferation of cyclooxygenase-depleted colorectal cancer cells. Cancer Res. 59:1999;2739-2746.
    • (1999) Cancer Res , vol.59 , pp. 2739-2746
    • Chinery, R.1    Coffey, R.J.2    Graves-Deal, R.3
  • 55
    • 0023818314 scopus 로고
    • Prostaglandin D2 formation and characterization of its synthetases in various tissues of adult rats
    • Ujihara M., Urade Y., Eguchi N., Hayashi H., Ikai K., Hayaishi O. Prostaglandin D2 formation and characterization of its synthetases in various tissues of adult rats. Arch Biochem Biophys. 260:1988;521-531.
    • (1988) Arch Biochem Biophys , vol.260 , pp. 521-531
    • Ujihara, M.1    Urade, Y.2    Eguchi, N.3    Hayashi, H.4    Ikai, K.5    Hayaishi, O.6
  • 56
    • 0030895048 scopus 로고    scopus 로고
    • A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection
    • Suzuki H., Kurihara Y., Takeya M., et al. A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection. Nature (London). 386:1997;292-296.
    • (1997) Nature (London) , vol.386 , pp. 292-296
    • Suzuki, H.1    Kurihara, Y.2    Takeya, M.3
  • 57
    • 0025612173 scopus 로고
    • Human macrophage scavenger receptors: Primary structure, expression, and localization in atherosclerotic lesions
    • Matsumoto A., Naito M., Itakura H., et al. Human macrophage scavenger receptors primary structure, expression, and localization in atherosclerotic lesions . Proc Natl Acad Sci USA. 87:1990;9133-9137.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 9133-9137
    • Matsumoto, A.1    Naito, M.2    Itakura, H.3
  • 58
    • 0031848185 scopus 로고    scopus 로고
    • Scavenger receptor family proteins: Roles for atherosclerosis, host defence and disorders of the central nervous system
    • Yamada Y., Doi T., Hamakubo T., Kodama T. Scavenger receptor family proteins roles for atherosclerosis, host defence and disorders of the central nervous system . Cell Mol Life Sci. 54:1998;628-640.
    • (1998) Cell Mol Life Sci , vol.54 , pp. 628-640
    • Yamada, Y.1    Doi, T.2    Hamakubo, T.3    Kodama, T.4
  • 59
    • 0030758289 scopus 로고    scopus 로고
    • Native and modified low density lipoproteins increase the functional expression of the macrophage class B scavenger receptor, CD36
    • Han J., Hajjar D.P., Febbraio M., Nicholson A.C. Native and modified low density lipoproteins increase the functional expression of the macrophage class B scavenger receptor, CD36. J Biol Chem. 272:1997;21654-21659.
    • (1997) J Biol Chem , vol.272 , pp. 21654-21659
    • Han, J.1    Hajjar, D.P.2    Febbraio, M.3    Nicholson, A.C.4
  • 60
    • 0032540325 scopus 로고    scopus 로고
    • Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma
    • Nagy L., Tontonoz P., Alvarez J.G., Chen H., Evans R.M. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. Cell. 93:1998;229-240.
    • (1998) Cell , vol.93 , pp. 229-240
    • Nagy, L.1    Tontonoz, P.2    Alvarez, J.G.3    Chen, H.4    Evans, R.M.5
  • 61
    • 0033595261 scopus 로고    scopus 로고
    • IL-4-dependent production of PPAR-γ ligands in macrophages by 12/15-lipoxygenase
    • Huang J.T., Welch J.S., Ricote M., et al. IL-4-dependent production of PPAR-γ ligands in macrophages by 12/15-lipoxygenase. Nature (London). 400:1999;378-382.
    • (1999) Nature (London) , vol.400 , pp. 378-382
    • Huang, J.T.1    Welch, J.S.2    Ricote, M.3
  • 62
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
    • Ricote M., Li A.C., Willson T.M., Kelly C.J., Glass C.K. The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation. Nature (London). 391:1998;79-82.
    • (1998) Nature (London) , vol.391 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 63
    • 0031888958 scopus 로고    scopus 로고
    • PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
    • Jiang C., Ting A.T., Seed B. PPAR-γ agonists inhibit production of monocyte inflammatory cytokines. Nature (London). 391:1998;82-86.
    • (1998) Nature (London) , vol.391 , pp. 82-86
    • Jiang, C.1    Ting, A.T.2    Seed, B.3
  • 64
    • 0032555196 scopus 로고    scopus 로고
    • Ligands for peroxisome proliferator-activated receptor gamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice
    • Elstner E., Muller C., Koshizuka K., et al. Ligands for peroxisome proliferator-activated receptor gamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice. Proc Natl Acad Sci USA. 95:1998;8806-8811.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8806-8811
    • Elstner, E.1    Muller, C.2    Koshizuka, K.3
  • 65
    • 0033546190 scopus 로고    scopus 로고
    • Endothelial cell apoptosis induced by the peroxisome proliferator-activated receptor (PPAR) ligand 15-deoxy-Delta12, 14-prostaglandin J2
    • Bishop-Bailey D., Hla T. Endothelial cell apoptosis induced by the peroxisome proliferator-activated receptor (PPAR) ligand 15-deoxy-Delta12, 14-prostaglandin J2. J Biol Chem. 274:1999;17042-17048.
    • (1999) J Biol Chem , vol.274 , pp. 17042-17048
    • Bishop-Bailey, D.1    Hla, T.2
  • 66
    • 0032586875 scopus 로고    scopus 로고
    • Activation of PPARgamma inhibits cell growth and induces apoptosis in human gastric cancer cells
    • Takahashi N., Okumura T., Motomura W., Fujimoto Y., Kawabata I., Kohgo Y. Activation of PPARgamma inhibits cell growth and induces apoptosis in human gastric cancer cells. FEBS Lett. 455:1999;135-139.
    • (1999) FEBS Lett , vol.455 , pp. 135-139
    • Takahashi, N.1    Okumura, T.2    Motomura, W.3    Fujimoto, Y.4    Kawabata, I.5    Kohgo, Y.6
  • 67
    • 0033533535 scopus 로고    scopus 로고
    • 15-Deoxy-Delta(12,14)-prostaglandin J(2), a ligand for peroxisome proliferator-activated receptor-γ, induces apoptosis in JEG3 choriocarcinoma cells
    • Keelan J.A., Sato T.A., Marvin K.W., Lander J., Gilmour R.S., Mitchell M.D. 15-Deoxy-Delta(12,14)-prostaglandin J(2), a ligand for peroxisome proliferator-activated receptor-γ, induces apoptosis in JEG3 choriocarcinoma cells. Biochem Biophys Res Commun. 262:1999;579-585.
    • (1999) Biochem Biophys Res Commun , vol.262 , pp. 579-585
    • Keelan, J.A.1    Sato, T.A.2    Marvin, K.W.3    Lander, J.4    Gilmour, R.S.5    Mitchell, M.D.6
  • 68
    • 0033605677 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo
    • Xin X., Yang S., Kowalski J., Gerritsen M.E. Peroxisome proliferator-activated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo. J Biol Chem. 274:1999;9116-9121.
    • (1999) J Biol Chem , vol.274 , pp. 9116-9121
    • Xin, X.1    Yang, S.2    Kowalski, J.3    Gerritsen, M.E.4
  • 69
    • 0027988554 scopus 로고
    • [[omega-(Heterocyclylamino)alkoxy]benzyl]-2,4-thiazolidinediones as potent antihyperglycemic agents
    • Cantello B.C., Cawthorne M.A., Cottam G.P., et al. [[omega-(Heterocyclylamino)alkoxy]benzyl]-2,4-thiazolidinediones as potent antihyperglycemic agents. J Med Chem. 37:1994;3977-3985.
    • (1994) J Med Chem , vol.37 , pp. 3977-3985
    • Cantello, B.C.1    Cawthorne, M.A.2    Cottam, G.P.3
  • 70
    • 0026664271 scopus 로고
    • New oral thiazolidinedione antidiabetic agents act as insulin sensitizers
    • Hofmann C.A., Colca J.R. New oral thiazolidinedione antidiabetic agents act as insulin sensitizers. Diabetes Care. 15:1992;1075-1078.
    • (1992) Diabetes Care , vol.15 , pp. 1075-1078
    • Hofmann, C.A.1    Colca, J.R.2
  • 71
    • 0027983920 scopus 로고
    • Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone
    • Nolan J.J., Ludvik B., Beerdsen P., Joyce M., Olefsky J. Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone. N Engl J Med. 331:1994;1188-1193.
    • (1994) N Engl J Med , vol.331 , pp. 1188-1193
    • Nolan, J.J.1    Ludvik, B.2    Beerdsen, P.3    Joyce, M.4    Olefsky, J.5
  • 72
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)
    • Lehmann J.M., Moore L.B., Smith-Oliver T.A., Wilkison W.O., Willson T.M., Kliewer S.A. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J Biol Chem. 270:1995;12953-12956.
    • (1995) J Biol Chem , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkison, W.O.4    Willson, T.M.5    Kliewer, S.A.6
  • 73
    • 0032989265 scopus 로고    scopus 로고
    • A novel N-aryl tyrosine activator of peroxisome proliferator-activated receptor-γ reverses the diabetic phenotype of the Zucker diabetic fatty rat
    • Brown K.K., Henke B.R., Blanchard S.G., et al. A novel N-aryl tyrosine activator of peroxisome proliferator-activated receptor-γ reverses the diabetic phenotype of the Zucker diabetic fatty rat. Diabetes. 48:1999;1415-1424.
    • (1999) Diabetes , vol.48 , pp. 1415-1424
    • Brown, K.K.1    Henke, B.R.2    Blanchard, S.G.3
  • 74
    • 0033525535 scopus 로고    scopus 로고
    • Novel peroxisome proliferator-activated receptor (PPAR) gamma and PPARdelta ligands produce distinct biological effects
    • Berger J., Leibowitz M.D., Doebber T.W., et al. Novel peroxisome proliferator-activated receptor (PPAR) gamma and PPARdelta ligands produce distinct biological effects. J Biol Chem. 274:1999;6718-6725.
    • (1999) J Biol Chem , vol.274 , pp. 6718-6725
    • Berger, J.1    Leibowitz, M.D.2    Doebber, T.W.3
  • 75
    • 0029793540 scopus 로고    scopus 로고
    • Hypoglycemic activity of a series of α-alkylthio and α-alkoxy carboxylic acids related to ciglitazone
    • Hulin B., Newton L.S., Lewis D.M., Genereux P.E., Gibbs E.M., Clark D.A. Hypoglycemic activity of a series of α-alkylthio and α-alkoxy carboxylic acids related to ciglitazone. J Med Chem. 39:1996;3897-3907.
    • (1996) J Med Chem , vol.39 , pp. 3897-3907
    • Hulin, B.1    Newton, L.S.2    Lewis, D.M.3    Genereux, P.E.4    Gibbs, E.M.5    Clark, D.A.6
  • 76
    • 0031013395 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs
    • Lehmann J.M., Lenhard J.M., Oliver B.B., Ringold G.M., Kliewer S.A. Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs. J Biol Chem. 272:1997;3406-3410.
    • (1997) J Biol Chem , vol.272 , pp. 3406-3410
    • Lehmann, J.M.1    Lenhard, J.M.2    Oliver, B.B.3    Ringold, G.M.4    Kliewer, S.A.5
  • 77
    • 0031694577 scopus 로고    scopus 로고
    • Activation of the peroxisome proliferator-activated receptor gamma promotes the development of colon tumors in C57BL/6J-APCMin/+ mice
    • Lefebvre A.M., Chen I., Desreumaux P., et al. Activation of the peroxisome proliferator-activated receptor gamma promotes the development of colon tumors in C57BL/6J-APCMin/+ mice. Nat Med. 4:1998;1053-1057.
    • (1998) Nat Med , vol.4 , pp. 1053-1057
    • Lefebvre, A.M.1    Chen, I.2    Desreumaux, P.3
  • 78
    • 0031667938 scopus 로고    scopus 로고
    • Activators of the nuclear receptor PPARgamma enhance colon polyp formation
    • Saez E., Tontonoz P., Nelson M.C., et al. Activators of the nuclear receptor PPARgamma enhance colon polyp formation. Nat Med. 4:1998;1058-1061.
    • (1998) Nat Med , vol.4 , pp. 1058-1061
    • Saez, E.1    Tontonoz, P.2    Nelson, M.C.3
  • 79
    • 0031595670 scopus 로고    scopus 로고
    • Activation of PPARgamma leads to inhibition of anchorage-independent growth of human colorectal cancer cells [see comments]
    • Brockman J.A., Gupta R.A., Dubois R.N. Activation of PPARgamma leads to inhibition of anchorage-independent growth of human colorectal cancer cells [see comments]. Gastroenterology. 115:1998;1049-1055.
    • (1998) Gastroenterology , vol.115 , pp. 1049-1055
    • Brockman, J.A.1    Gupta, R.A.2    Dubois, R.N.3
  • 80
    • 0031671246 scopus 로고    scopus 로고
    • Differentiation and reversal of malignant changes in colon cancer through PPARgamma [see comments]
    • Sarraf P., Mueller E., Jones D., et al. Differentiation and reversal of malignant changes in colon cancer through PPARgamma [see comments]. Nat Med. 4:1998;1046-1052.
    • (1998) Nat Med , vol.4 , pp. 1046-1052
    • Sarraf, P.1    Mueller, E.2    Jones, D.3
  • 81
    • 0031993322 scopus 로고    scopus 로고
    • Terminal differentiation of human breast cancer through PPAR gamma
    • Mueller E., Sarraf P., Tontonoz P., et al. Terminal differentiation of human breast cancer through PPAR gamma. Mol Cell. 1:1998;465-470.
    • (1998) Mol Cell , vol.1 , pp. 465-470
    • Mueller, E.1    Sarraf, P.2    Tontonoz, P.3
  • 82
    • 12644265334 scopus 로고    scopus 로고
    • Terminal differentiation of human liposarcoma cells induced by ligands for the peroxisome proliferator-activated receptor γ and the retinoid X receptor
    • Tontonoz P., Singer S., Forman B.M., et al. Terminal differentiation of human liposarcoma cells induced by ligands for the peroxisome proliferator-activated receptor γ and the retinoid X receptor. Proc Natl Acad Sci USA. 94:1997;237-241.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 237-241
    • Tontonoz, P.1    Singer, S.2    Forman, B.M.3
  • 83
    • 0033616795 scopus 로고    scopus 로고
    • Induction of solid tumor differentiation by the peroxisome proliferator- activated receptor-γ ligand troglitazone in patients with liposarcoma
    • Demetri G.D., Fletcher C.D., Mueller E., et al. Induction of solid tumor differentiation by the peroxisome proliferator- activated receptor-γ ligand troglitazone in patients with liposarcoma. Proc Natl Acad Sci USA. 96:1999;3951-3956.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 3951-3956
    • Demetri, G.D.1    Fletcher, C.D.2    Mueller, E.3
  • 84
    • 0033564698 scopus 로고    scopus 로고
    • Cyclo-oxygenase-2-derived prostacyclin mediates embryo implantation in the mouse via PPARdelta
    • Lim H., Gupta R.A., Ma W.G., et al. Cyclo-oxygenase-2-derived prostacyclin mediates embryo implantation in the mouse via PPARdelta. Genes Dev. 13:1999;1561-1574.
    • (1999) Genes Dev , vol.13 , pp. 1561-1574
    • Lim, H.1    Gupta, R.A.2    Ma, W.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.